Research and education at IGP
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Newsletter
Recent research papers from IGP
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Vaccaro, Alessandra; van de Walle, Tiarne; Ramachandran, Mohanraj; Essand, Magnus; Dimberg, Anna
Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer
2023
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Mannes, Marco; Pechtl, Veronika; Hafner, Susanne; Dopler, Arthur; Eriksson, Oskar; Manivel, Vivek Anand; Wohlgemuth, Lisa; Messerer, David Alexander Christian; Schrezenmeier, Hubert; Nilsson Ekdahl, Kristina; Nilsson, Bo; Jacobsen, Eva -Maria; Hoenig, Manfred; Huber-Lang, Markus; Braun, Christian K.; Schmidt, Christoph Q.
Complement and platelets: prothrombotic cell activation requires membrane attack complex-induced release of danger signals
2023
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Hård, Joanna; Mold, Jeff E; Eisfeldt, Jesper; Tellgren-Roth, Christian; Häggqvist, Susana; Bunikis, Ignas; Contreras-Lopez, Orlando; Chin, Chen-Shan; Nordlund, Jessica; Rubin, Carl-Johan; Feuk, Lars; Michaëlsson, Jakob; Ameur, Adam
Long-read whole-genome analysis of human single cells.
2023
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Lysenkova Wiklander, Mariya; Övernäs, Elin; Lagensjö, Johanna; Raine, Amanda; Petri, Anna; Wiman, Ann-Christin; Ramsell, Jon; Marincevic-Zuniga, Yanara; Gezelius, Henrik; Martin, Tom; Bunikis, Ignas; Ekberg, Sara; Erlandsson, Rikard; Larsson, Pontus; Mosbech, Mai-Britt; Häggqvist, Susana; Kerje, Susanne; Feuk, Lars; Ameur, Adam; Liljedahl, Ulrika; Nordlund, Jessica
Genomic, transcriptomic and epigenomic sequencing data of the B-cell leukemia cell line REH
2023
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Armand, Philippe; Zinzani, Pier Luigi; Lee, Hun Ju; Johnson, Nathalie A.; Brice, Pauline; Radford, John; Ribrag, Vincent; Molin, Daniel; Vassilakopoulos, Theodoros P.; Tomita, Akihiro; von Tresckow, Bastian; Shipp, Margaret A.; Herrera, Alex F.; Lin, Jianxin; Kim, Eunhee; Chakraborty, Samhita; Marinello, Patricia; Moskowitz, Craig H.
Five-year follow-up of KEYNOTE-087: pembrolizumab monotherapy for relapsed/refractory classical Hodgkin lymphoma
2023
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Oroujeni, Maryam; Bezverkhniaia, Ekaterina A.; Xu, Tianqi; Liu, Yongsheng; V. Plotnikov, Evgenii; Klint, Susanne; Ryer, Eva; Karlberg, Ida; Orlova, Anna; Frejd, Fredrik Y.; Tolmachev, Vladimir
Evaluation of affinity matured Affibody molecules for imaging of the immune checkpoint protein B7-H3
2023
Welcome to IGP
The department conducts advanced research and education in areas such as clinical immunology, medical genetics and genomics, pathology, oncology, neuro-oncology, vascular biology, molecular tools and medical radiation sciences.
Some of our activities are integrated with clinics at Uppsala University Hospital.
Find examples of research at the Department in Our research in images.
Follow us on Twitter: @IgpUu
New research findings from IGP
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Genetics influence the risk of blood clots in oral contraceptive users
2023-10-20
Women with a high genetic predisposition for blood clots are six times more likely to develop a blood clot during the first two years of using contraceptive pills according to a new study from IGP. The results have been published in the American Journal of Obstetrics and Gynaecology.
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Contraceptive pills protect against rheumatoid arthritis
2023-10-11
Contraceptive pills can reduce the risk of rheumatoid arthritis, while hormone treatment in connection with menopause can increase the risk later in life. In a new study of more than 200,000 women in the UK, researchers at IGP have discovered connections between the use of sex hormones and the risk of developing rheumatoid arthritis. The results have been published in the journal Rheumatology.
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New mechanism behind cancer cell growth revealed
2023-09-27
The protein EZH2 can interact with a specific RNA molecule to block genes that are important for tumour growth. This is shown in a new study from IGP that reveals one of the mechanisms behind the growth of cancer cells in the blood cancer multiple myeloma. These findings might contribute to the development of new treatments for multiple myeloma patients. The study is published in the journal Haematologica.