Research and education at IGP
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Recent research papers from IGP
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Karlsson, Ida; Mellqvist, Eva; Persson, Paula
Temporal and spatial dynamics of Fusarium spp. and mycotoxins in Swedish cereals during 16 years
2023
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Guenter, Alexander; Sothilingam, Vithiyanjali; Orlich, Michael M.; Nordheim, Alfred; Seeliger, Mathias W.; Muehlfriedel, Regine
Mural Serum Response Factor (SRF) Deficiency Provides Insights into Retinal Vascular Functionality and Development
2023
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Ali, Arwa; Gao, Menghan; Iskantar, Alexandros; Wang, Hai; Karlsson-Parra, Alex; Yu, Di; Jin, Chuan
Proinflammatory allogeneic dendritic cells enhance the therapeutic efficacy of systemic anti-4-1BB treatment
2023
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Bonfiglio, Silvia; Sutton, Lesley-Ann; Ljungström, Viktor; Capasso, Antonella; Pandzic, Tatjana; Weström, Simone; Foroughi-Asl, Hassan; Skaftason, Aron; Gellerbring, Anna; Lyander, Anna; Gandini, Francesca; Gaidano, Gianluca; Trentin, Livio; Bonello, Lisa; Reda, Gianluigi; Bodor, Csaba; Stavroyianni, Niki; Tam, Constantine S.; Marasca, Robert; Forconi, Francesco; Panayiotidis, Pahayiotis; Ringshausen, Ingo; Kaksic, Ozren; Frustaci, Anna Maria; Iyengar, Sunil; Coscia, Marta; Mulligan, Stephen P.; Ysebaert, Loic; Strugov, Vladimir; Pavlovsky, Carolina; Walewska, Reneta; Osterborg, Anders; Cortese, Diego; Ranghetti, Pamela; Baliakas, Panagiotis; Stamatopoulos, Kostas; Scarfo, Lydia; Rosenquist, Richard; Ghia, Paolo
BTK and PLCG2 remain unmutated in one-third of patients with CLL relapsing on ibrutinib
2023
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van de Vegte, Yordi; Eppinga, Ruben P.; van der Ende, M. Yldau; Hagemeijer, Yanick; Mahendran, Yuvaraj V.; Salfati, Elias Y.; Smith, Albert E.; Tan, Vanessa; Arking, Dan V.; Ntalla, Ioanna; Appel, Emil A.; Schurmann, Claudia; Brody, Jennifer; Rueedi, Rico; Polasek, Ozren; Sveinbjornsson, Gardar; Lecoeur, Cecile; Ladenvall, Claes; Zhao, Jing Hua; Isaacs, Aaron; Wang, Lihua; Luan, Jian'an; Hwang, Shih-Jen; Mononen, Nina U.; Auro, Kirsi F.; Jackson, Anne; Bielak, Lawrence; Zeng, Linyao; Shah, Nabi; Nethander, Maria; Campbell, Archie; Rankinen, Tuomo; Pechlivanis, Sonali; Qi, Lu; Zhao, Wei; Rizzi, Federica; Tanaka, Toshiko; Robino, Antonietta; Cocca, Massimiliano; Lange, Leslie; Mueller-Nurasyid, Martina; Roselli, Carolina E.; Zhang, Weihua; Kleber, Marcus J.; Guo, Xiuqing; Lin, Henry E.; Pavani, Francesca; Galesloot, Tessel; Noordam, Raymond E.; Milaneschi, Yuri; Schraut, Katharina; den Hoed, Marcel; Degenhardt, Frauke E.; Trompet, Stella; van den Berg, Marten; Pistis, Giorgio; Tham, Yih-Chung S.; Weiss, Stefan L.; Sim, Xueling J.; Li, Hengtong M.; van der Most, Peter; Nolte, Ilja; Lyytikaeinen, Leo-Pekka R.; Said, M. Abdullah; Witte, Daniel; Iribarren, Carlos M.; Launer, Lenore S.; Ring, Susan; de Vries, Paul; Sever, Peter P.; Linneberg, Allan; Bottinger, Erwin M.; Padmanabhan, Sandosh; Psaty, Bruce; Sotoodehnia, Nona; Kolcic, Ivana; Roshandel, Delnaz D.; Paterson, Andrew O.; Arnar, David F.; Gudbjartsson, Daniel; Holm, Hilma; Balkau, Beverley T.; Silva, Claudia H.; Newton-Cheh, Christopher; Nikus, Kjell; Salo, Perttu L.; Mohlke, Karen A.; Peyser, Patricia; Schunkert, Heribert; Lorentzon, Mattias; Lahti, Jari C.; Rao, Dabeeru C.; Cornelis, Marilyn D.; Faul, Jessica A.; Smith, Jennifer; Stolarz-Skrzypek, Katarzyna; Bandinelli, Stefania; Concas, Maria Pina; Sinagra, Gianfranco; Meitinger, Thomas; Waldenberger, Melanie F.; Sinner, Moritz; Strauch, Konstantin E.; Delgado, Graciela D.; Taylor, Kent; Yao, Jie; Foco, Luisa; Melander, Olle; de Graaf, Jacqueline; de Mutsert, Renee; de Geus, Eco J. C.; Johansson, Åsa; Joshi, Peter K.; Lind, Lars; Franke, Andre W.; Macfarlane, Peter V.; Tarasov, Kirill; Tan, Nicholas B.; Felix, Stephan; Tai, E-Shyong Q.; Quek, Debra; Snieder, Harold; Ormel, Johan; Ingelsson, Martin; Lindgren, Cecilia P.; Morris, Andrew T.; Raitakari, Olli; Hansen, Torben; Assimes, Themistocles; Gudnason, Vilmundur J.; Timpson, Nicholas C.; Morrison, Alanna B.; Munroe, Patricia P.; Strachan, David; Grarup, Niels; Loos, Ruth J. F. R.; Heckbert, Susan; Vollenweider, Peter; Hayward, Caroline; Stefansson, Kari; Froguel, Philippe; Groop, Leif J.; Wareham, Nicholas M.; van Duijn, Cornelia F.; Feitosa, Mary J.; O'Donnell, Christopher; Kaehoenen, Mika; Perola, Markus; Boehnke, Michael; Kardia, Sharon L. R.; Erdmann, Jeanette; Palmer, Colin N. A.; Ohlsson, Claes J.; Porteous, David G.; Eriksson, Johan; Bouchard, Claude; Moebus, Susanne; Kraft, Peter R.; Weir, David; Cusi, Daniele; Ferrucci, Luigi; Ulivi, Sheila; Girotto, Giorgia; Correa, Adolfo; Kaeaeb, Stefan; Peters, Annette C.; Chambers, John S.; Kooner, Jaspal; Maerz, Winfried I.; Rotter, Jerome A.; Hicks, Andrew; Smith, J. Gustav; Kiemeney, Lambertus A. L. M. O.; Mook-Kanamori, Dennis; Penninx, Brenda W. J. H.; Gyllensten, Ulf B.; Wilson, James; Burgess, Stephen; Sundstroem, Johan; Lieb, Wolfgang; Jukema, J. Wouter; Eijgelsheim, Mark; Lakatta, Edward L. M.; Cheng, Ching-Yu; Doerr, Marcus; Wong, Tien-Yin; Sabanayagam, Charumathi J.; Oldehinkel, Albertine; Riese, Harriette; Lehtimaeki, Terho; Verweij, Niek; van der Harst, Pim
Genetic insights into resting heart rate and its role in cardiovascular disease
2023
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Milosevic, Vladan; Edelmann, Reidunn J.; Winge, Ingeborg; Strell, Carina; Mezheyeuski, Artur; Knutsvik, Gøril; Askeland, Cecilie; Wik, Elisabeth; Akslen, Lars A.; Östman, Arne
Vessel size as a marker of survival in estrogen receptor positive breast cancer
2023
Welcome to IGP
The department conducts advanced research and education in areas such as clinical immunology, medical genetics and genomics, pathology, oncology, neuro-oncology, vascular biology, molecular tools and medical radiation sciences.
Some of our activities are integrated with clinics at Uppsala University Hospital.
Find examples of research at the Department in Our research in images.
Follow us on Twitter: @IgpUu
New research findings from IGP
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Improved tumour killing immune cells against brain cancers
2023-08-22
Researchers at IGP have demonstrated a mechanism for how cancer killing immune cells called CAR- T cells sometimes are prematurely exhausted and fail to kill the cancer cells. They also present new CAR-T cells against brain tumours that lack this unwanted exhaustion feature. The future aim is to use these CAR-T cells to treat brain cancer. The study has been published in the journal Nature Communications.
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New method to identify mutations in childhood brain tumours
2023-08-14
Researchers at IGP have developed a new method to find mutations in brain tumours in children. They could also show that the mutations identified by them changes how cancer cells respond to a cancer drug. These findings could lead to better diagnostics and more individualized treatment of children with brain tumours.
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Newly discovered genetic abnormality affects leukemia prognosis
2023-07-04
The blood cancer form acute myeloid leukemia (AML) is an extremely heterogeneous disease where disease development and therapeutic approach are mainly dictaded by genetic alterations in the malignant cells. In a recent study from IGP, the researchers show that a certain type of abnormality in the gene RUNX1 affects the classification of patients with AML and thereby the optimal therapy selection.