Recent research papers from IGP
Burman, Pia; Casar Borota, Olivera; Perez-Rivas, Luis Gustavo; Dekkers, Olaf M.
Aggressive Pituitary Tumors and Pituitary Carcinomas: From Pathology to Treatment
Naslunda, Olivia; Lipatnikova, Anna; Denes, Anna; Lindskog, Cecilia; Bontell, Thomas Olsson; Smits, Anja; Jakola, Asgeir S.; Corell, Alba
Meningioma classification by immunohistochemistry: A replicability study
Letter to the editor
Kruse, Bastian; Buzzai, Anthony C.; Shridhar, Naveen; Braun, Andreas D.; Gellert, Susan; Knauth, Kristin; Pozniak, Joanna; Peters, Johannes; Dittmann, Paulina; Mengoni, Miriam; van der Sluis, Tetje Cornelia; Höhn, Simon; Antoranz, Asier; Krone, Anna; Fu, Yan; Yu, Di; Essand, Magnus; Geffers, Robert; Mougiakakos, Dimitrios; Kahlfuss, Sascha; Kashkar, Hamid; Gaffal, Evelyn; Bosisio, Francesca M.; Bechter, Oliver; Rambow, Florian; Marine, Jean-Christophe; Kastenmüller, Wolfgang; Müller, Andreas J.; Tüting, Thomas
CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours
Nesti, Cedric; Bräutigam, Konstantin; Benavent, Marta; Bernal, Laura; Boharoon, Hessa; Botling, Johan; Bouroumeau, Antonin; Brcic, Iva; Brunner, Maximilian; Cadiot, Guillaume; Camara, Maria; Christ, Emanuel; Clerici, Thomas; Clift, Ashley K.; Clouston, Hamish; Cobianchi, Lorenzo; Cwikla, Jaroslaw B.; Daskalakis, Kosmas; Frilling, Andrea; Garcia-Carbonero, Rocio; Grozinsky-Glasberg, Simona; Hernando, Jorge; Hervieu, Valerie; Hofland, Johannes; Holmager, Pernille; Inzani, Frediano; Jann, Henning; Jimenez-Fonseca, Paula; Kacmaz, Enes; Kaemmerer, Daniel; Kaltsas, Gregory; Klimàcek, Branislav; Knigge, Ulrich; Kolasinska-Cwikla, Agnieszka; Kolb, Walter; Kos-Kudla, Beata; Kunze, Catarina Alisa; Landolfi, Stefania; La Rosa, Stefano; Lopez, Carlos Lopez; Lorenz, Kerstin; Matter, Maurice; Mazal, Peter; Mestre-Alagarda, Claudia; del Burgo, Patricia Morales; van Dijkum, Els J. M. Nieveen; Oleinikov, Kira; Orci, Lorenzo A.; Panzuto, Francesco; Pavel, Marianne; Perrier, Marine; Reims, Henrik Mikael; Rindi, Guido; Rinke, Anja; Rinzivillo, Maria; Sagaert, Xavier; Satiroglu, Ilker; Selberherr, Andreas; Siebenhuener, Alexander R.; Tesselaar, Margot E. T.; Thalhammer, Michael J.; Thiis-Evensen, Espen; Toumpanakis, Christos; Vandamme, Timon; van den Berg, José G.; Vanoli, Alessandro; van Velthuysen, Marie-Louise F.; Verslype, Chris; Vorburger, Stephan A.; Lugli, Alessandro; Ramage, John; Zwahlen, Marcel; Perren, Aurel; Kaderli, Reto M.
Hemicolectomy versus appendectomy for patients with appendiceal neuroendocrine tumours 1-2 cm in size: a retrospective, Europe-wide, pooled cohort study
Gear, Jonathan; Stokke, Caroline; Terwinghe, Christelle; Gnesin, Silvano; Sandström, Mattias; Tran-Gia, Johannes; Cremonesi, Marta; Cicone, Francesco; Verburg, Fredrik; Hustinx, Roland; Giovanella, Luca; Herrmann, Ken; Gabina, Pablo Minguez
EANM enabling guide: how to improve the accessibility of clinical dosimetry
Welcome to IGP
The department conducts advanced research and education in areas such as clinical immunology, medical genetics and genomics, pathology, oncology, neuro-oncology, vascular biology, molecular tools and medical radiation sciences.
Some of our activities are integrated with clinics at Uppsala University Hospital.
Find examples of research at the Department in Our research in images.
Follow us on Twitter: @IgpUu
New research findings from IGP
New mechanism behind cancer cell growth revealed
The protein EZH2 can interact with a specific RNA molecule to block genes that are important for tumour growth. This is shown in a new study from IGP that reveals one of the mechanisms behind the growth of cancer cells in the blood cancer multiple myeloma. These findings might contribute to the development of new treatments for multiple myeloma patients. The study is published in the journal Haematologica.
Improved tumour killing immune cells against brain cancers
Researchers at IGP have demonstrated a mechanism for how cancer killing immune cells called CAR- T cells sometimes are prematurely exhausted and fail to kill the cancer cells. They also present new CAR-T cells against brain tumours that lack this unwanted exhaustion feature. The future aim is to use these CAR-T cells to treat brain cancer. The study has been published in the journal Nature Communications.
New method to identify mutations in childhood brain tumours
Researchers at IGP have developed a new method to find mutations in brain tumours in children. They could also show that the mutations identified by them changes how cancer cells respond to a cancer drug. These findings could lead to better diagnostics and more individualized treatment of children with brain tumours.