Publikationer i DiVA – Magnus Essand

CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers

Jin, Chuan; Ma, Jing; Ramachandran, Mohanraj; Yu, Di et al.

Ingår i Nature Biomedical Engineering, s. 830-841, 2022.

DOI för CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers Ladda ner fulltext (pdf) av CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers

CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation

Konstantinidis, Evangelos; Molisak, Agnieszka; Perrin, Florian; Streubel-Gallasch, Linn et al.

Ingår i Molecular Therapy - Nucleic Acids, s. 450-461, 2022.

DOI för CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation Ladda ner fulltext (pdf) av CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation

Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response

Jin, Chuan; Ali, Arwa; Iskantar, Alexandros; Fotaki, Grammatiki et al.

Ingår i Oncoimmunology, 2022.

DOI för Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response Ladda ner fulltext (pdf) av Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response

Ixovex-1, a novel oncolytic E1B-mutated adenovirus

Anwar, Mohiemen; Arendt, Maja-Louise; Ramachandran, Mohanraj; Carlsson, Anette et al.

Ingår i Cancer Gene Therapy, s. 1628-1635, 2022.

DOI för Ixovex-1, a novel oncolytic E1B-mutated adenovirus Ladda ner fulltext (pdf) av Ixovex-1, a novel oncolytic E1B-mutated adenovirus

Targeting circulating monocytes with CCL2-loaded liposomes armed with an oncolytic adenovirus

Iscaro, Alessandra; Jones, Christian; Forbes, Neil; Mughal, Amina et al.

Ingår i Nanomedicine, 2022.

DOI för Targeting circulating monocytes with CCL2-loaded liposomes armed with an oncolytic adenovirus

Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy

Sjöholm, Therese; Korenyushkin, Alexander; Gammelgård, Gustav; Sarén, Tina et al.

Ingår i Cancer Imaging, 2022.

DOI för Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy Ladda ner fulltext (pdf) av Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy

ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression

Darweesh, Mahmoud; Younis, Shady; Hajikhezri, Zamaneh; Ali, Arwa et al.

Ingår i Frontiers in Immunology, 2022.

DOI för ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression Ladda ner fulltext (pdf) av ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression

Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma

van Hooren, Luuk; Vaccaro, Alessandra; Ramachandran, Mohanraj; Vazaios, Konstantinos et al.

Ingår i Nature Communications, 2021.

DOI för Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma Ladda ner fulltext (pdf) av Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma

Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy

Deng, Siyuan; Iscaro, Alessandra; Zambito, Giorgia; Mijiti, Yimin et al.

Ingår i Nanomaterials, 2021.

DOI för Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy Ladda ner fulltext (pdf) av Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy

IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma

Martikainen, Miika; Ramachandran, Mohanraj; Lugano, Roberta; Ma, Jing et al.

Ingår i MOLECULAR THERAPY-ONCOLYTICS, s. 37-46, 2021.

DOI för IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma Ladda ner fulltext (pdf) av IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma

Perivascular macrophages regulate blood flow following tissue damage

Vågesjö, Evelina; Parv, Kristel; Ahl, David; Seignez, Cedric et al.

Ingår i Circulation Research, s. 1694-1707, 2021.

DOI för Perivascular macrophages regulate blood flow following tissue damage

Tertiary Lymphoid Structures in the Central Nervous System: Implications for Glioblastoma

van de Walle, Tiarne; Vaccaro, Alessandra; Ramachandran, Mohanraj; Pietilä, Ilkka et al.

Ingår i Frontiers in Immunology, 2021.

DOI för Tertiary Lymphoid Structures in the Central Nervous System: Implications for Glioblastoma Ladda ner fulltext (pdf) av Tertiary Lymphoid Structures in the Central Nervous System: Implications for Glioblastoma

Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain

Rostami, Jinar; Fotaki, Grammatiki; Sirois, Julien; Mzezewa, Ropafadzo et al.

Ingår i Journal of Neuroinflammation, 2020.

DOI för Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain Ladda ner fulltext (pdf) av Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain

Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer

Ma, Jing; Ramachandran, Mohanraj; Jin, Chuan; Quijano-Rubio, Clara et al.

Ingår i Cell Death and Disease, 2020.

DOI för Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer Ladda ner fulltext (pdf) av Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer

TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment

Depreter, Barbara; Weening, Karin E.; Vandepoele, Karl; Essand, Magnus et al.

Ingår i Haematologica, s. 1306-1316, 2020.

DOI för TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment Ladda ner fulltext (pdf) av TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment

Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

Georganaki, Maria; Ramachandran, Mohanraj; Tuit, Sander; Nunez, Nicolas Gonzalo et al.

Ingår i Oncoimmunology, 2020.

DOI för Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy Ladda ner fulltext (pdf) av Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

Čančer, Matko; Hutter, Sonja; Holmberg Olausson, Karl; Rosén, Gabriela et al.

Ingår i Cell Stem Cell, s. 855-870, 2019.

DOI för Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy Ladda ner fulltext (pdf) av Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Xie, Yuan; Sundström, Anders; Maturi, Naga P; Tan, E-Jean et al.

Ingår i Journal of Pathology, s. 228-240, 2019.

DOI för LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Virus-Based Immunotherapy of Glioblastoma

Martikainen, Miika; Essand, Magnus

Ingår i Cancers, 2019.

DOI för Virus-Based Immunotherapy of Glioblastoma Ladda ner fulltext (pdf) av Virus-Based Immunotherapy of Glioblastoma

A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia

Enblad, Gunilla; Karlsson, Hannah; Gammelgård, Gustav; Wenthe, Jessica et al.

Ingår i Clinical Cancer Research, s. 6185-6194, 2018.

DOI för A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia

Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models

Fotaki, Grammatiki; Jin, Chuan; Kerzeli, Iliana Kyriaki; Ramachandran, Mohanraj et al.

Ingår i Oncoimmunology, 2018.

DOI för Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models Ladda ner fulltext (pdf) av Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models

CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis

Lugano, Roberta; Vemuri, Kalyani; Yu, Di; Bergqvist, Michael et al.

Ingår i Journal of Clinical Investigation, s. 3280-3297, 2018.

DOI för CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis Ladda ner fulltext (pdf) av CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis

Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

Roche, Francis P.; Pietilä, Ilkka; Kaito, Hiroshi; Sjöström, Elisabet O. et al.

Ingår i Molecular Cancer Therapeutics, s. 1961-1972, 2018.

DOI för Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity Ladda ner fulltext (pdf) av Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

Modifying melanoma immune microenvironment by heterologous prime-boost vaccination with adenovirus and Modified Vaccinia Ankara virus vectors

Shridhar, N.; Ruotsalainen, J.; van der Sluis, T.; Rogava, M. et al.

Ingår i Experimental dermatology, s. E54-E55, 2018.

Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth

Younis, Shady; Kamel, Wael; Falkeborn, Tina; Wang, Hao et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. E3808-E3816, 2018.

DOI för Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth

Perivascular macrophages regulate blood flow following tissue damage

Vågesjö, Evelina; Seignez, Cedric; Christoffersson, Gustaf; Herrera Hidalgo, Carmen et al.

Ingår i European Journal of Clinical Investigation, s. 44-45, 2018.

DOI för Perivascular macrophages regulate blood flow following tissue damage

Pro-inflammatory allogeneic DCs promote activation of bystander immune cells and thereby license antigen-specific T-cell responses

Fotaki, Grammatiki; Jin, Chuan; Ramachandran, Mohanraj; Kerzeli, Iliana Kyriaki et al.

Ingår i Oncoimmunology, 2018.

DOI för Pro-inflammatory allogeneic DCs promote activation of bystander immune cells and thereby license antigen-specific T-cell responses

Adenovirus, Semliki Forest virus and vaccinia virus-induced immunogenic cell death augments oncolytic virus immunotherapy

Ma, Jing; Ramachandran, Mohanraj; Jin, Chuan; Essand, Magnus et al.

Ingår i Scandinavian Journal of Immunology, s. 341-341, 2017.

CAR T-Cells with Induced Secretion of Helicobacter Pylori Neutrophil-Activating Protein (HP-NAP) Yields Improved Anti-Tumor Activity and Reduced Immunosuppression

Essand, Magnus; Ma, Jing; Jin, Chuan; Ramachandran, Mohanraj et al.

Ingår i Molecular Therapy, s. 288-288, 2017.

Immunological biomarkers correlate to survival in CAR19-treated patients

Lövgren, Tanja; Wenthe, Jessica; Karlsson, S. C. Hannah; Gammelgård, Gustav et al.

Ingår i Scandinavian Journal of Immunology, s. 337-337, 2017.

Oncolytic alphavirus SFV-VA7 efficiently eradicates subcutaneous and orthotopic human prostate tumours in mice

Martikainen, Miika; Ruotsalainen, Janne; Tuomela, Johanna; Harkonen, Pirkko et al.

Ingår i British Journal of Cancer, s. 51-55, 2017.

DOI för Oncolytic alphavirus SFV-VA7 efficiently eradicates subcutaneous and orthotopic human prostate tumours in mice

PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c

Pan, Gang; Ameur, Adam; Enroth, Stefan; Bysani, Madhusudhan et al.

Ingår i Nucleic Acids Research, s. 2408-2422, 2017.

DOI för PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c

Preclinical Evaluation of AdVince, an Oncolytic Adenovirus Adapted for Treatment of Liver Metastases from Neuroendocrine Cancer

Yu, Di; Leja, Justyna; Loskog, Angelica S.; Hellman, Per et al.

Ingår i Neuroendocrinology, s. 54-66, 2017.

DOI för Preclinical Evaluation of AdVince, an Oncolytic Adenovirus Adapted for Treatment of Liver Metastases from Neuroendocrine Cancer

Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus

Ramachandran, Mohanraj; Yu, Di; Dyczynski, Matheus; Baskaran, Sathishkumar et al.

Ingår i Clinical Cancer Research, s. 1519-1530, 2017.

DOI för Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus

The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells

Ramachandran, Mohanraj; Dimberg, Anna; Essand, Magnus

Ingår i Seminars in Cancer Biology, s. 23-35, 2017.

DOI för The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells Ladda ner fulltext (pdf) av The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells

A Clinical Trial Using Third Generation CD19 Targeting CAR T Cells for Relapsed Lymphoma and Leukemia

Enblad, Gunilla; Karlsson, Hannah; Wenthe, Jessica; Wikström, Kristina I. et al.

Ingår i Molecular Therapy, s. S295-S296, 2016.

Allogeneic dendritic cells (AlloDCs) transduced with an infection enhanced adenovirus as adjuvant for cancer immunotherapy

Fotaki, Grammatiki; Jin, Chuan; Karlsson-Parra, Alex; Yu, Di et al.

Ingår i CANCER IMMUNOLOGY RESEARCH, 2016.

DOI för Allogeneic dendritic cells (AlloDCs) transduced with an infection enhanced adenovirus as adjuvant for cancer immunotherapy

Avidity characterization of genetically engineered T-cells with novel and established approaches

Hillerdal, Victoria; Boura, Vanessa F.; Björkelund, Hanna; Andersson, Karl et al.

Ingår i BMC Immunology, 2016.

DOI för Avidity characterization of genetically engineered T-cells with novel and established approaches Ladda ner fulltext (pdf) av Avidity characterization of genetically engineered T-cells with novel and established approaches

CD19-targeting third generation CAR T cells for relapsed and refractory lymphoma and leukemia: report from the Swedish phase Ulla trial

Enblad, Gunilla; Karlsson, Hannah; Wikström, Kristina I.; Essand, Magnus et al.

Ingår i CANCER IMMUNOLOGY RESEARCH, 2016.

DOI för CD19-targeting third generation CAR T cells for relapsed and refractory lymphoma and leukemia: report from the Swedish phase Ulla trial

HAdV-2-suppressed growth of SV40 T antigen-transformed mouse mammary epithelial cell-induced tumours in SCID mice

Wu, Chengjun; Cao, Xiaofang; Yu, Di; Huijbers, Elisabeth J. M. et al.

Ingår i Virology, s. 44-50, 2016.

DOI för HAdV-2-suppressed growth of SV40 T antigen-transformed mouse mammary epithelial cell-induced tumours in SCID mice

Heparanase Promotes Glioma Progression and is Inversely Correlated with Patient Survival.

Kundu, Soumi; Xiong, Anqi; Spyrou, Argyris; Wicher, Grzegorz et al.

Ingår i Molecular Cancer Research, s. 1243-1253, 2016.

DOI för Heparanase Promotes Glioma Progression and is Inversely Correlated with Patient Survival.

Long-term episomal gene transfer for safe engineering of T cells for adoptive cell therapy of cancer

Jin, Chuan; Ramachandran, Mohanraj; Fotaki, Grammatiki; Nilsson, Berith et al.

Ingår i CANCER IMMUNOLOGY RESEARCH, 2016.

DOI för Long-term episomal gene transfer for safe engineering of T cells for adoptive cell therapy of cancer

miR-196a Is Specifically Regulated in FDG-PET Positive and Negative Small Intestinal Neuroendocrine Tumor Patients at Late Stage of Disease

Giandomenico, V; Li, Su-Chen; Lind, Thomas; Boccherini, M. et al.

Ingår i Neuroendocrinology, s. 115-115, 2016.

Prospects to improve chimeric antigen receptor T-cell therapy for solid tumors

Jin, Chuan; Yu, Di; Essand, Magnus

Ingår i Immunotherapy, s. 1355-1361, 2016.

DOI för Prospects to improve chimeric antigen receptor T-cell therapy for solid tumors

Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer

Jin, Chuan; Fotaki, Grammatiki; Ramachandran, Mohanraj; Nilsson, Berith et al.

Ingår i EMBO Molecular Medicine, s. 702-711, 2016.

DOI för Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer Ladda ner fulltext (pdf) av Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer

Chimeric Antigen Receptor-Engineered T Cells for the Treatment of Metastatic Prostate Cancer

Hillerdal, Victoria; Essand, Magnus

Ingår i BioDrugs, s. 75-89, 2015.

DOI för Chimeric Antigen Receptor-Engineered T Cells for the Treatment of Metastatic Prostate Cancer Ladda ner fulltext (pdf) av Chimeric Antigen Receptor-Engineered T Cells for the Treatment of Metastatic Prostate Cancer

Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Langenkamp, Elise; Zhang, Lei; Lugano, Roberta; Huang, Hua et al.

Ingår i Cancer Research, s. 4504-4516, 2015.

DOI för Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Immunological shielding by induced recruitment of regulatory T lymphocytes delays rejection of islets transplanted to muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Waldén, Tomas B; Carlsson, Per-Ola et al.

Ingår i Cell Transplantation, s. 263-276, 2015.

DOI för Immunological shielding by induced recruitment of regulatory T lymphocytes delays rejection of islets transplanted to muscle

Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Waldén, Tomas B; Carlsson, Per-Ola et al.

Ingår i Cell Transplantation, s. 263-276, 2015.

DOI för Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle

Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model

Fransson, Moa; Brännström, Johan; Duprez, Ida; Essand, Magnus et al.

Ingår i Regenerative Medicine Research, 2015.

DOI för Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model Ladda ner fulltext (pdf) av Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model

Other Novel Therapies: Biomarkers, microRNAs and microRNA Inhibitors, DNA Methylation, Epigenetics, Immunotherapy and Virotherapy

Giandomenico, Valeria; Thirlwell, Chrissie; Essand, Magnus

Ingår i Neuroendocrine Tumors, s. 248-262, 2015.

DOI för Other Novel Therapies: Biomarkers, microRNAs and microRNA Inhibitors, DNA Methylation, Epigenetics, Immunotherapy and Virotherapy

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Zhang, Lei; Kundu, Soumi; Feenstra, Tjerk; Li, Xiujuan et al.

Ingår i Science Signaling, 2015.

DOI för Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Third Generation CD19-CAR T Cells for Relapsed and Refractory Lymphoma and Leukemia Report from the Swedish Phase I/IIa Trial

Enblad, Gunilla; Karlsson, Hannah; Wikström, Kristina; Essand, Magnus et al.

Ingår i Blood, 2015.

A Hexon and Fiber-modified Adenovirus Expressing CD40L Improves the Antigen Presentation Capacity of Dendritic Cells

Liljenfeldt, Lina; Yu, Di; Chen, Liye; Essand, Magnus et al.

Ingår i Journal of immunotherapy (1997), s. 155-162, 2014.

DOI för A Hexon and Fiber-modified Adenovirus Expressing CD40L Improves the Antigen Presentation Capacity of Dendritic Cells

Adenovirus Encoded Helicobacter pylori Neutrophil Activating Protein Promotes Maturation of DCs with Th-1 Polarization, Improved Antigen Presentation and Migration

Ramachandran, Mohanraj; Jin, Chuan; Yu, Di; Eriksson, Fredrik et al.

Ingår i Molecular Therapy, s. S242-S243, 2014.

Allogeneic lymphocyte-licensed DCs expand T cells withimproved antitumor activity and resistance to oxidative stress andimmunosuppressive factors

Jin, Chuan; Yu, Di; Hillerdal, Victoria; Wallgren, AnnaCarin et al.

Ingår i Molecular Therapy Methods & Clinical Development, 2014.

DOI för Allogeneic lymphocyte-licensed DCs expand T cells withimproved antitumor activity and resistance to oxidative stress andimmunosuppressive factors

Allogeneic Lymphocyte-Licensed DCs Expand TCR/CAR-Engineered T Cells, Which Are Insensitive To Oxidative Stress and Immunosuppressive Factors

Jin, Chuan; Yu, Di; Karlsson-Parra, Alex; Essand, Magnus

Ingår i Molecular Therapy, s. S62-S62, 2014.

Engineering Regulatory Cells With a T Cell Receptor for Controlled Activation

Hillerdal, Victoria; Berglund, David; Boura, Vanessa; Jin, Chuan et al.

Ingår i Molecular Therapy, s. S180-S180, 2014.

Histidine-Rich Glycoprotein (HRG): A Novel Gene-Therapy Effector for the Treatment of Cancer

Roche, Francis P.; Ohlin, Elisabet K.; Essand, Magnus; Claesson-Welsh, Lena

Ingår i Molecular Therapy, s. S243-S244, 2014.

Long-term episomal gene transfer for safe engineering of T-cells for adoptive cell therapy of cancer

Jin, Chuan; Ramachandran, Mohanraj; Fotaki, Grammatiki; Nilsson, Bo et al.

Ingår i Human Gene Therapy, s. A50-A50, 2014.

Preclinical Safety Assessment of Ad[I/PPT-E1A], a Novel Oncolytic Adenovirus for Prostate Cancer

Schenk, Ellen; Essand, Magnus; Kraaij, Robert; Adamson, Rachel et al.

Ingår i Human Gene Therapy Clinical Development, s. 7-15, 2014.

DOI för Preclinical Safety Assessment of Ad[I/PPT-E1A], a Novel Oncolytic Adenovirus for Prostate Cancer

Strategical steering of the immune system: induction of leukocyte vascular chaperoning increases functional blood flow responses in ischemic muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Korsgren, Olle; Essand, Magnus et al.

Ingår i The FASEB Journal, 2014.

Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice

Hillerdal, Victoria; Ramachandran, Mohanraj; Leja, Justyna; Essand, Magnus

Ingår i BMC Cancer, s. 30-, 2014.

DOI för Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice Ladda ner fulltext (pdf) av Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice

Vector-Encoded Helicobacter pylori Neutrophil-Activating Protein Promotes Maturation of Dendritic Cells with Th1 Polarization and Improved Migration

Ramachandran, Mohanraj; Jin, Chuan; Yu, Di; Eriksson, Fredrik et al.

Ingår i Journal of Immunology, s. 2287-2296, 2014.

DOI för Vector-Encoded Helicobacter pylori Neutrophil-Activating Protein Promotes Maturation of Dendritic Cells with Th1 Polarization and Improved Migration

Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures

Yu, Di; Jin, Chuan; Ramachandran, Mohanraj; Xu, Jing et al.

Ingår i PLOS ONE, s. e54952-, 2013.

DOI för Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures Ladda ner fulltext (pdf) av Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures

An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors

Ramachandran, Mohanraj; Yu, Di; Wanders, Alkwin; Essand, Magnus et al.

Ingår i Molecular Therapy, s. 2008-2018, 2013.

DOI för An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors Ladda ner fulltext (pdf) av An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors

Combining CAR T cells and the Bcl-2 family apoptosis inhibitor ABT-737 for treating B-cell malignancy

Karlsson, S. C. Hannah; Lindqvist, A. C.; Fransson, Moa; Paul-Wetterberg, Gabriella et al.

Ingår i Cancer Gene Therapy, s. 386-393, 2013.

DOI för Combining CAR T cells and the Bcl-2 family apoptosis inhibitor ABT-737 for treating B-cell malignancy

Genetically engineered T cells for the treatment of cancer

Essand, Magnus; Loskog, Angelica S I

Ingår i Journal of Internal Medicine, s. 166-181, 2013.

DOI för Genetically engineered T cells for the treatment of cancer

Histidine-Rich Glycoprotein (HRG): A Novel Gene-Therapy Effector for the Treatment of Cancer

Roche, Francis P.; Ohlin, Elisabet; Essand, Magnus; Claesson-Welsh, Lena

Ingår i Molecular Therapy, s. S241-S241, 2013.

Islet Engraftment and Revascularization in Clinical and Experimental Transplantation

Molnár, Christian; Essand, Magnus; Wennberg, Lars; Berne, Christian et al.

Ingår i Cell Transplantation, s. 243-251, 2013.

DOI för Islet Engraftment and Revascularization in Clinical and Experimental Transplantation

Macrophage delivery of an oncolytic virus abolishes tumor regrowth and metastasis after chemotherapy or irradiation

Muthana, M.; Rodrigues, S.; Chen, Y. -Y; Welford, A. et al.

Ingår i Cancer Research, s. 490-495, 2013.

DOI för Macrophage delivery of an oncolytic virus abolishes tumor regrowth and metastasis after chemotherapy or irradiation

Strategic recruitment of proangiogenic leukocytes to the ischemic hindlimb increases functional tissue perfusion

Vågesjö, Evalina; Christoffersson, Gustaf; Korsgren, Olle; Essand, Magnus et al.

Ingår i European Journal of Clinical Investigation, s. 27-27, 2013.

Tat‐PTD‐modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy

Jin, Chuan; Yu, Di; Čančer, Matko; Nilsson, Berith et al.

Ingår i Human Gene Therapy, s. 766-775, 2013.

DOI för Tat‐PTD‐modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy Ladda ner fulltext (pdf) av Tat‐PTD‐modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy

Virotherapy of Neuroendocrine Tumors

Essand, Magnus

Ingår i Neuroendocrinology, s. 26-34, 2013.

DOI för Virotherapy of Neuroendocrine Tumors

Age-related somatic structural changes in the nuclear genome of human blood cells

Forsberg, Lars A.; Rasi, Chiara; Razzaghian, Hamid R; Pakalapati, Geeta et al.

Ingår i American Journal of Human Genetics, s. 217-228, 2012.

DOI för Age-related somatic structural changes in the nuclear genome of human blood cells

CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery

Fransson, Moa; Piras, Elena; Burman, Joachim; Nilsson, Berith et al.

Ingår i Journal of Neuroinflammation, s. 112-, 2012.

DOI för CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery Ladda ner fulltext (pdf) av CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery

In Vitro Primary Cell Culture as a Physiologically Relevant Method for Preclinical Testing of Human Oncolytic Adenovirus

Adamson, R. E.; Frazier, A. A.; Evans, H.; Chambers, K. F. et al.

Ingår i Human Gene Therapy, s. 218-230, 2012.

DOI för In Vitro Primary Cell Culture as a Physiologically Relevant Method for Preclinical Testing of Human Oncolytic Adenovirus

T cells engineered with a T cell receptor against the prostate antigen TARP specifically kill HLA-A2⁺ prostate and breast cancer cells

Hillerdal, Victoria; Nilsson, Berith; Carlsson, Björn; Eriksson, Fredrik et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 15877-15881, 2012.

DOI för T cells engineered with a T cell receptor against the prostate antigen TARP specifically kill HLA-A2⁺ prostate and breast cancer cells

Adenovirus with Hexon Tat-Protein Transduction Domain Modification Exhibits Increased Therapeutic Effect in Experimental Neuroblastoma and Neuroendocrine Tumors

Yu, Di; Jin, Chuan; Leja, Justyna; Majdalani, Nadim et al.

Ingår i Journal of Virology, s. 13114-13123, 2011.

DOI för Adenovirus with Hexon Tat-Protein Transduction Domain Modification Exhibits Increased Therapeutic Effect in Experimental Neuroblastoma and Neuroendocrine Tumors Ladda ner fulltext (pdf) av Adenovirus with Hexon Tat-Protein Transduction Domain Modification Exhibits Increased Therapeutic Effect in Experimental Neuroblastoma and Neuroendocrine Tumors

Oncolytic adenovirus modified with somatostatin motifs for selective infection of neuroendocrine tumor cells

Leja, Justyna; Yu, Di; Nilsson, Berith; Gedda, Lars et al.

Ingår i Gene Therapy, s. 1052-1062, 2011.

DOI för Oncolytic adenovirus modified with somatostatin motifs for selective infection of neuroendocrine tumor cells

Oncolytic Viruses for the Treatment of Neuroendocrine Tumors

Essand, Magnus; Leja, Justyna; Giandomenico, Valeria; Öberg, Kjell E.

Ingår i Hormone and Metabolic Research, s. 877-883, 2011.

DOI för Oncolytic Viruses for the Treatment of Neuroendocrine Tumors

The HDAC Inhibitor FK228 Enhances Adenoviral Transgene Expression by a Transduction-Independent Mechanism but Does Not Increase Adenovirus Replication

Danielsson, Angelika; Dzojic, Helena; Rashkova, Victoria; Cheng, Wing-Shing et al.

Ingår i PLoS ONE, s. e14700-, 2011.

DOI för The HDAC Inhibitor FK228 Enhances Adenoviral Transgene Expression by a Transduction-Independent Mechanism but Does Not Increase Adenovirus Replication

Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors

Muthana, Munitta; Giannoudis, Athina; Scott, Simon D.; Fang, Hsin-Yu et al.

Ingår i Cancer Research, s. 1805-1815, 2011.

DOI för Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors

An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

Danielsson, Angelika; Elgue, Graciela; Nilsson, Berith M.; Nilsson, Bo et al.

Ingår i Gene Therapy, s. 752-762, 2010.

DOI för An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

Clinical Adenoviral Gene Therapy for Prostate Cancer

Schenk, Ellen; Essand, Magnus; Bangma, Chris

Ingår i Human Gene Therapy, s. 807-813, 2010.

DOI för Clinical Adenoviral Gene Therapy for Prostate Cancer

Double-detargeted oncolytic adenovirus shows replication arrest in liver cells and retains neuroendocrine cell killing ability

Leja, Justyna; Nilsson, Berith; Yu, Di; Gustafson, Elisabet et al.

Ingår i PLOS ONE, s. e8916-, 2010.

DOI för Double-detargeted oncolytic adenovirus shows replication arrest in liver cells and retains neuroendocrine cell killing ability

Gene Transfer Vectors Targeted to Human Prostate Cancer: Do We Need Better Preclinical Testing Systems?

Maitland, Norman; Chambers, Karen; Georgopoulos, Lindsay; Simpson-Holley, Martha et al.

Ingår i Human Gene Therapy, s. 815-827, 2010.

DOI för Gene Transfer Vectors Targeted to Human Prostate Cancer: Do We Need Better Preclinical Testing Systems?

Generation of antigen-specific cytolytic T cells for prostate cancer therapy

Rashkova, Victoria; Essand, Magnus

Ingår i Human Gene Therapy, s. 1422-1422, 2010.

High frequency of prostate antigen-directed T cells in cancer patients compared to healthy age-matched individuals

Forsberg, Ole; Carlsson, Björn; Malmström, Per-Uno; Ullenhag, Gustav et al.

Ingår i The Prostate, s. 70-81, 2009.

DOI för High frequency of prostate antigen-directed T cells in cancer patients compared to healthy age-matched individuals Ladda ner fulltext (pdf) av High frequency of prostate antigen-directed T cells in cancer patients compared to healthy age-matched individuals

Midgut carcinoid patients display increased numbers of regulatory T cells in peripheral blood with infiltration into tumor tissue

Vikman, Sofia; Sommaggio, Roberta; De La Torre, Manuel; Öberg, Kjell et al.

Ingår i Acta Oncologica, s. 391-400, 2009.

DOI för Midgut carcinoid patients display increased numbers of regulatory T cells in peripheral blood with infiltration into tumor tissue Ladda ner fulltext (pdf) av Midgut carcinoid patients display increased numbers of regulatory T cells in peripheral blood with infiltration into tumor tissue

Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas

Leja, Justyna; Essaghir, Ahmed; Essand, Magnus; Wester, Kenneth et al.

Ingår i Modern Pathology, s. 261-272, 2009.

DOI för Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas

CD8(+) T cells against multiple tumor-associated antigens in peripheral blood of midgut carcinoid patients

Vikman, Sofia; Giandomenico, Valeria; Sommaggio, Roberta; Öberg, Kjell et al.

Ingår i Cancer Immunology and Immunotherapy, s. 399-409, 2008.

DOI för CD8(+) T cells against multiple tumor-associated antigens in peripheral blood of midgut carcinoid patients

CpG oligonucleotides demonstrate increased therapeutic efficacy compared to BCG in an aggressive orthotopic bladder cancer model

Ninalga, Christina; Mangsbo, Sara; Loskog, Angelica; Essand, Magnus et al.

Ingår i Journal of immunotherapy (1997), s. 34-42, 2008.

DOI för CpG oligonucleotides demonstrate increased therapeutic efficacy compared to BCG in an aggressive orthotopic bladder cancer model

CpG Therapy is Superior to BCG in an Orthotopic Bladder Cancer Model and Generates CD4+ T-cell Immunity

Mangsbo, Sara M; Ninalga, Christina; Essand, Magnus; Loskog, Angelica et al.

Ingår i Journal of immunotherapy (1997), s. 34-42, 2008.

DOI för CpG Therapy is Superior to BCG in an Orthotopic Bladder Cancer Model and Generates CD4+ T-cell Immunity

Increased therapeutic efficacy of the prostate-specific oncolytic adenovirus Ad[I/PPT-E1A] by reduction of the insulator size and introduction of the full-length E3 region

Danielsson, Angelika; Dzojic, H; Nilsson, B; Essand, M

Ingår i Cancer Gene Therapy, s. 203-213, 2008.

DOI för Increased therapeutic efficacy of the prostate-specific oncolytic adenovirus Ad[I/PPT-E1A] by reduction of the insulator size and introduction of the full-length E3 region

Strategic use of an adenoviral vector for rapid and efficient ex vivo-generation of cytomegalovirus pp65-reactive cytolytic and helper T cells

Forsberg, Ole; Carlsson, Björn; Tötterman, Thomas H.; Essand, Magnus

Ingår i British Journal of Haematology, s. 188-199, 2008.

DOI för Strategic use of an adenoviral vector for rapid and efficient ex vivo-generation of cytomegalovirus pp65-reactive cytolytic and helper T cells Ladda ner fulltext (pdf) av Strategic use of an adenoviral vector for rapid and efficient ex vivo-generation of cytomegalovirus pp65-reactive cytolytic and helper T cells

A novel chromogranin-A promoter-driven oncolytic adenovirus for midgut carcinoid therapy

Leja, Justyna; Dzojic, Helena; Gustafson, Elisabet; Öberg, Kjell et al.

Ingår i Clinical Cancer Research, s. 2455-2462, 2007.

DOI för A novel chromogranin-A promoter-driven oncolytic adenovirus for midgut carcinoid therapy

Characterization of human prostate and breast cancer cell lines for experimental T cell-based immunotherapy

Carlsson, Björn; Forsberg, Ole; Bengtsson, Mats; Tötterman, Thomas H. et al.

Ingår i The Prostate, s. 389-395, 2007.

DOI för Characterization of human prostate and breast cancer cell lines for experimental T cell-based immunotherapy Ladda ner fulltext (pdf) av Characterization of human prostate and breast cancer cell lines for experimental T cell-based immunotherapy

Two-step amplification of the human PPT sequence provides specific gene expression in an immunocompetent murine prostate cancer model

Dzojic, Helena; Cheng, Wing-Shing; Essand, Magnus

Ingår i Cancer Gene Therapy, s. 233-240, 2007.

DOI för Two-step amplification of the human PPT sequence provides specific gene expression in an immunocompetent murine prostate cancer model

Adenovirus-Mediated CD40 Ligand Therapy Induces Tumor Cell Apoptosis and Systemic Immunity in the TRAMP-C2 Mouse Prostate Cancer Model

Dzojic, Helena; Loskog, Angelica; Tötterman, Thomas H.; Essand, Magnus

Ingår i The Prostate, s. 831-838, 2006.

DOI för Adenovirus-Mediated CD40 Ligand Therapy Induces Tumor Cell Apoptosis and Systemic Immunity in the TRAMP-C2 Mouse Prostate Cancer Model