Publikationer i DiVA – Patrick Micke

An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers

Mezheyeuski, Artur; Backman, Max; Mattsson, Johanna Sofia Margareta; Martin-Bernabe, Alfonso et al.

Ingår i EBioMedicine, 2023.

DOI för An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers Ladda ner fulltext (pdf) av An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers

Fibroblast subsets in non-small cell lung cancer: Associations with survival, mutations, and immune features

Pellinen, Teijo; Paavolainen, Lassi; Martín-Bernabé, Alfonso; Papatella Araujo, Renata et al.

Ingår i Journal of the National Cancer Institute, s. 71-82, 2023.

DOI för Fibroblast subsets in non-small cell lung cancer: Associations with survival, mutations, and immune features Ladda ner fulltext (pdf) av Fibroblast subsets in non-small cell lung cancer: Associations with survival, mutations, and immune features

Matched Analyses of Brain Metastases versus Primary Non-Small Cell Lung Cancer Reveal a Unique microRNA Signature

Tsakonas, Georgios; Koulouris, Andreas; Kazmierczak, Dominika; Botling, Johan et al.

Ingår i International Journal of Molecular Sciences, 2023.

DOI för Matched Analyses of Brain Metastases versus Primary Non-Small Cell Lung Cancer Reveal a Unique microRNA Signature Ladda ner fulltext (pdf) av Matched Analyses of Brain Metastases versus Primary Non-Small Cell Lung Cancer Reveal a Unique microRNA Signature

Phenotypic characterization of spatial immune infiltration niches in non-small cell lung cancer

Gerdtsson, Anna Sandstrom; Knulst, Mattis; Botling, Johan; Mezheyeuski, Artur et al.

Ingår i Oncoimmunology, 2023.

DOI för Phenotypic characterization of spatial immune infiltration niches in non-small cell lung cancer Ladda ner fulltext (pdf) av Phenotypic characterization of spatial immune infiltration niches in non-small cell lung cancer

Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer

Backman, Max; Strell, Carina; Lindberg, Amanda; Mattsson, Johanna Sofia Margareta et al.

Ingår i European Journal of Cancer, s. 40-52, 2023.

DOI för Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer Ladda ner fulltext (pdf) av Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer

A Novel Pancreatic Cancer Mini-tumor Model to Study Desmoplasia and Myofibroblastic Cancer-Associated Fibroblast Differentiation

Harryvan, T.J.; Hawinkels, L.J.A.C.; Östman, A.; ten Dijke, P. et al.

Ingår i Gastro Hep Advances, s. 678-681, 2022.

DOI för A Novel Pancreatic Cancer Mini-tumor Model to Study Desmoplasia and Myofibroblastic Cancer-Associated Fibroblast Differentiation Ladda ner fulltext (pdf) av A Novel Pancreatic Cancer Mini-tumor Model to Study Desmoplasia and Myofibroblastic Cancer-Associated Fibroblast Differentiation

Comparison of ROS1-rearrangement detection methods in a cohort of surgically resected non-small cell lung carcinomas.

Thurfjell, Viktoria; Micke, Patrick; Yu, Hui; Krupar, Rosemarie et al.

Ingår i Translational lung cancer research, s. 2477-2494, 2022.

DOI för Comparison of ROS1-rearrangement detection methods in a cohort of surgically resected non-small cell lung carcinomas.

Difficulties in diagnostics of lung tumours in biopsies: an interpathologist concordance study evaluating the international diagnostic guidelines

Ericson Lindquist, Kajsa; Ciornei, Cristina; Westbom-Fremer, Sofia; Gudinaviciene, Inga et al.

Ingår i Journal of Clinical Pathology, s. 302-309, 2022.

DOI för Difficulties in diagnostics of lung tumours in biopsies: an interpathologist concordance study evaluating the international diagnostic guidelines Ladda ner fulltext 1 (pdf) av Difficulties in diagnostics of lung tumours in biopsies: an interpathologist concordance study evaluating the international diagnostic guidelines Ladda ner fulltext 2 (pdf) av Difficulties in diagnostics of lung tumours in biopsies: an interpathologist concordance study evaluating the international diagnostic guidelines

Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion

Papadakos, Konstantinos S.; Lundgren, Sebastian; Gialeli, Chrysostomi; Micke, Patrick et al.

Ingår i Oncoimmunology, 2022.

DOI för Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion Ladda ner fulltext (pdf) av Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion

Highly elevated systemic inflammation is a strong independent predictor of early mortality in advanced non-small cell lung cancer

Isaksson, Johan; Wennström, Leo; Brandén, Eva; Koyi, Hirsh et al.

Ingår i Cancer Treatment and Research Communications, 2022.

DOI för Highly elevated systemic inflammation is a strong independent predictor of early mortality in advanced non-small cell lung cancer Ladda ner fulltext (pdf) av Highly elevated systemic inflammation is a strong independent predictor of early mortality in advanced non-small cell lung cancer

Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma

Khadse, Anand; Haakensen, Vilde D.; Silwal-Pandit, Laxmi; Hamfjord, Julian et al.

Ingår i Frontiers in Oncology, 2022.

DOI för Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma Ladda ner fulltext (pdf) av Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma

Spatial Immunology in Liver Metastases from Colorectal Carcinoma according to the Histologic Growth Pattern

Garcia-Vicien, Gemma; Mezheyeuski, Artur; Micke, Patrick; Ruiz, Nuria et al.

Ingår i Cancers, 2022.

DOI för Spatial Immunology in Liver Metastases from Colorectal Carcinoma according to the Histologic Growth Pattern Ladda ner fulltext (pdf) av Spatial Immunology in Liver Metastases from Colorectal Carcinoma according to the Histologic Growth Pattern

Tumour-infiltrating lymphocytes add prognostic information for patients with low-risk DCIS: findings from the SweDCIS randomised radiotherapy trial

Schiza, Aglaia; Thurfjell, Viktoria; Stenmark Tullberg, Axel; Olofsson, Helena et al.

Ingår i European Journal of Cancer, s. 128-137, 2022.

DOI för Tumour-infiltrating lymphocytes add prognostic information for patients with low-risk DCIS: findings from the SweDCIS randomised radiotherapy trial Ladda ner fulltext (pdf) av Tumour-infiltrating lymphocytes add prognostic information for patients with low-risk DCIS: findings from the SweDCIS randomised radiotherapy trial

An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation

Sabatier, Pierre; Beusch, Christian M.; Saei, Amir A.; Aoun, Mike et al.

Ingår i Nature Communications, 2021.

DOI för An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation Ladda ner fulltext (pdf) av An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation

Evaluation of NTRK immunohistochemistry as a screening method for NTRK gene fusion detection in non-small cell lung cancer

Elfving, Hedvig; Broström, Erika; Moens, Lotte N.J.; Almlöf, Jonas et al.

Ingår i Lung Cancer, s. 53-59, 2021.

DOI för Evaluation of NTRK immunohistochemistry as a screening method for NTRK gene fusion detection in non-small cell lung cancer

FGFR1 overexpression in non-small cell lung cancer is mediated by genetic and epigenetic mechanisms and is a determinant of FGFR1 inhibitor response

Bogatyrova, Olga; Mattsson, Johanna S M; Ross, Edith M.; Sanderson, Michael P. et al.

Ingår i European Journal of Cancer, s. 136-149, 2021.

DOI för FGFR1 overexpression in non-small cell lung cancer is mediated by genetic and epigenetic mechanisms and is a determinant of FGFR1 inhibitor response Ladda ner fulltext (pdf) av FGFR1 overexpression in non-small cell lung cancer is mediated by genetic and epigenetic mechanisms and is a determinant of FGFR1 inhibitor response

High Density of NRF2 Expression in Malignant Cells Is Associated with Increased Risk of CNS Metastasis in Early-Stage NSCLC

Tsakonas, Georgios; Martin-Bernabe, Alfonso; Rounis, Konstantinos; Moreno-Ruiz, Pablo et al.

Ingår i Cancers, 2021.

DOI för High Density of NRF2 Expression in Malignant Cells Is Associated with Increased Risk of CNS Metastasis in Early-Stage NSCLC Ladda ner fulltext (pdf) av High Density of NRF2 Expression in Malignant Cells Is Associated with Increased Risk of CNS Metastasis in Early-Stage NSCLC

Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene

Doffe, Flora; Carbonnier, Vincent; Tissier, Manon; Leroy, Bernard et al.

Ingår i Cell Death and Differentiation, s. 1477-1492, 2021.

DOI för Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene Ladda ner fulltext (pdf) av Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene

Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer

Backman, Max; La Fleur, Linnea; Kurppa, Pinja; Djureinovic, Dijana et al.

Ingår i Journal of Pathology, s. 243-256, 2021.

DOI för Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer Ladda ner fulltext (pdf) av Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer

PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung

Goldmann, Torsten; Marwitz, Sebastian; Nitschkowski, Dorte; Krupar, Rosemarie et al.

Ingår i Cancer Immunology and Immunotherapy, s. 2577-2587, 2021.

DOI för PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung Ladda ner fulltext (pdf) av PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung

Plasma Proteome Fingerprints Reveal Distinctiveness and Clinical Outcome of SARS-CoV-2 Infection

Bauer, Wolfgang; Weber, Marcus; Diehl-Wiesenecker, Eva; Galtung, Noa et al.

Ingår i Viruses, 2021.

DOI för Plasma Proteome Fingerprints Reveal Distinctiveness and Clinical Outcome of SARS-CoV-2 Infection Ladda ner fulltext (pdf) av Plasma Proteome Fingerprints Reveal Distinctiveness and Clinical Outcome of SARS-CoV-2 Infection

Plasma Proteomic Analysis in Non-Small Cell Lung Cancer Patients Treated with PD-1/PD-L1 Blockade

Eltahir, Mohamed; Isaksson, Johan; Mattsson, Johanna Sofia Margareta; Karre, Klas et al.

Ingår i Cancers, 2021.

DOI för Plasma Proteomic Analysis in Non-Small Cell Lung Cancer Patients Treated with PD-1/PD-L1 Blockade Ladda ner fulltext (pdf) av Plasma Proteomic Analysis in Non-Small Cell Lung Cancer Patients Treated with PD-1/PD-L1 Blockade

Programmed Cell Death Ligand 1 Expression in Resected Non-Small Cell Lung Cancer

Yu, Hui; Brustugun, Odd Terje; Ekman, Simon; Botling, Johan et al.

Ingår i Clinical Lung Cancer, s. 555-562, 2021.

DOI för Programmed Cell Death Ligand 1 Expression in Resected Non-Small Cell Lung Cancer

Stromal FAP is an independent poor prognosis marker in non-small cell lung adenocarcinoma and associated with p53 mutation

Moreno-Ruiz, Pablo; Corvigno, Sara; te Grootenhuis, Nienke C.; La Fleur, Linnéa et al.

Ingår i Lung Cancer, s. 10-19, 2021.

DOI för Stromal FAP is an independent poor prognosis marker in non-small cell lung adenocarcinoma and associated with p53 mutation Ladda ner fulltext (pdf) av Stromal FAP is an independent poor prognosis marker in non-small cell lung adenocarcinoma and associated with p53 mutation

Targeting hepatocyte growth factor in epithelial-stromal interactions in an in vitro experimental model of human periodontitis

Yamaguchi, Yoko; Saito, Akira; Horie, Masafumi; Aoki, Akira et al.

Ingår i Odontology, s. 912-920, 2021.

DOI för Targeting hepatocyte growth factor in epithelial-stromal interactions in an in vitro experimental model of human periodontitis Ladda ner fulltext (pdf) av Targeting hepatocyte growth factor in epithelial-stromal interactions in an in vitro experimental model of human periodontitis

Targeting MARCO and IL-37R on immunosuppressive macrophages in lung cancer blocks regulatory T cells and supports cytotoxic lymphocyte function

La Fleur, Linnea; Botling, Johan; He, Fei; Pelicano, Catarina et al.

Ingår i Cancer Research, s. 956-967, 2021.

DOI för Targeting MARCO and IL-37R on immunosuppressive macrophages in lung cancer blocks regulatory T cells and supports cytotoxic lymphocyte function

TGF-beta-mediated epithelial-mesenchymal transition and tumor-promoting effects in CMT64 cells are reflected in the transcriptomic signature of human lung adenocarcinoma

Miyashita, Naoya; Enokido, Takayoshi; Horie, Masafumi; Fukuda, Kensuke et al.

Ingår i Scientific Reports, 2021.

DOI för TGF-beta-mediated epithelial-mesenchymal transition and tumor-promoting effects in CMT64 cells are reflected in the transcriptomic signature of human lung adenocarcinoma Ladda ner fulltext (pdf) av TGF-beta-mediated epithelial-mesenchymal transition and tumor-promoting effects in CMT64 cells are reflected in the transcriptomic signature of human lung adenocarcinoma

The Immune Landscape of Colorectal Cancer

Mezheyeuski, Artur; Micke, Patrick; Martin-Bernabe, Alfonso; Backman, Max et al.

Ingår i Cancers, 2021.

DOI för The Immune Landscape of Colorectal Cancer Ladda ner fulltext (pdf) av The Immune Landscape of Colorectal Cancer

The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types

Micke, Patrick; Strell, Carina; Mattsson, Johanna Sofia Margareta; Martin-Bernabe, Alfonso et al.

Ingår i EBioMedicine, 2021.

DOI för The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types Ladda ner fulltext (pdf) av The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types

An immune gene expression signature distinguishes central nervous system metastases from primary tumours in non-small-cell lung cancer

Tsakonas, Georgios; Lewensohn, Rolf; Botling, Johan; Ortiz-Villalon, Cristian et al.

Ingår i European Journal of Cancer, s. 24-34, 2020.

DOI för An immune gene expression signature distinguishes central nervous system metastases from primary tumours in non-small-cell lung cancer Ladda ner fulltext (pdf) av An immune gene expression signature distinguishes central nervous system metastases from primary tumours in non-small-cell lung cancer

ASCL1 promotes tumor progression through cell-autonomous signaling and immune modulation in a subset of lung adenocarcinoma

Miyashita, Naoya; Horie, Masafumi; Mikami, Yu; Urushiyama, Hirokazu et al.

Ingår i Cancer Letters, s. 121-132, 2020.

DOI för ASCL1 promotes tumor progression through cell-autonomous signaling and immune modulation in a subset of lung adenocarcinoma

Comprehensive analysis of RNA binding motif protein 3 (RBM3) in non-small cell lung cancer

Salomonsson, Annette; Micke, Patrick; Mattsson, Johanna S M; La Fleur, Linnéa et al.

Ingår i Cancer Medicine, s. 5609-5619, 2020.

DOI för Comprehensive analysis of RNA binding motif protein 3 (RBM3) in non-small cell lung cancer Ladda ner fulltext (pdf) av Comprehensive analysis of RNA binding motif protein 3 (RBM3) in non-small cell lung cancer

Diagnostic Value of Insulinoma-Associated Protein 1 (INSM1) and Comparison With Established Neuroendocrine Markers in Pulmonary Cancers: A Comprehensive Study and Review of the Literature

Staaf, Johan; Tran, Lena; Söderlund, Linnea; Nodin, Björn et al.

Ingår i Archives of Pathology & Laboratory Medicine, s. 1075-1085, 2020.

DOI för Diagnostic Value of Insulinoma-Associated Protein 1 (INSM1) and Comparison With Established Neuroendocrine Markers in Pulmonary Cancers: A Comprehensive Study and Review of the Literature

PD-L1 expression in gastroenteropancreatic neuroendocrine neoplasms grade 3

Ali, Abir Salwa; Langer, Seppo W.; Federspiel, Birgitte; Hjortland, Geir Olav et al.

Ingår i PLOS ONE, 2020.

DOI för PD-L1 expression in gastroenteropancreatic neuroendocrine neoplasms grade 3 Ladda ner fulltext (pdf) av PD-L1 expression in gastroenteropancreatic neuroendocrine neoplasms grade 3

Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis

Kramer, Frederike; Dernedde, Jens; Mezheyeuski, Artur; Tauber, Rudolf et al.

Ingår i Haematologica, s. 2083-2094, 2020.

DOI för Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis Ladda ner fulltext (pdf) av Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis

Quantitative, qualitative and spatial analysis of lymphocyte infiltration in periampullary and pancreatic adenocarcinoma

Lundgren, Sebastian; Elebro, Jacob; Heby, Margareta; Nodin, Björn et al.

Ingår i International Journal of Cancer, s. 3461-3473, 2020.

DOI för Quantitative, qualitative and spatial analysis of lymphocyte infiltration in periampullary and pancreatic adenocarcinoma Ladda ner fulltext (pdf) av Quantitative, qualitative and spatial analysis of lymphocyte infiltration in periampullary and pancreatic adenocarcinoma

The Novel Anti-cMet Antibody seeMet 12 Potentiates Sorafenib Therapy and Radiotherapy in a Colorectal Cancer Model

Spiegelberg, Diana; Lundgren Mortensen, Anja Charlotte; Palupi, Kartika Dyah; Micke, Patrick et al.

Ingår i Frontiers in Oncology, 2020.

DOI för The Novel Anti-cMet Antibody seeMet 12 Potentiates Sorafenib Therapy and Radiotherapy in a Colorectal Cancer Model Ladda ner fulltext (pdf) av The Novel Anti-cMet Antibody seeMet 12 Potentiates Sorafenib Therapy and Radiotherapy in a Colorectal Cancer Model

The protein expression profile of ACE2 in human tissues

Noraddin, Feria Hikmet; Méar, Loren; Edvinsson, Åsa; Micke, Patrick et al.

Ingår i Molecular Systems Biology, 2020.

DOI för The protein expression profile of ACE2 in human tissues

Topographical Distribution and Spatial Interactions of Innate and Semi-Innate Immune Cells in Pancreatic and Other Periampullary Adenocarcinoma

Lundgren, Sebastian; Micke, Patrick; Elebro, Jacob; Heby, Margareta et al.

Ingår i Frontiers in Immunology, 2020.

DOI för Topographical Distribution and Spatial Interactions of Innate and Semi-Innate Immune Cells in Pancreatic and Other Periampullary Adenocarcinoma Ladda ner fulltext (pdf) av Topographical Distribution and Spatial Interactions of Innate and Semi-Innate Immune Cells in Pancreatic and Other Periampullary Adenocarcinoma

A clonal expression biomarker associates with lung cancer mortality

Biswas, Dhruva; Birkbak, Nicolai J.; Rosenthal, Rachel; Hiley, Crispin T. et al.

Ingår i Nature Medicine, s. 1540-1548, 2019.

DOI för A clonal expression biomarker associates with lung cancer mortality

A combined gene expression tool for parallel histological prediction and gene fusion detection in non-small cell lung cancer

Karlsson, Anna; Cirenajwis, Helena; Ericson-Lindquist, Kajsa; Brunnström, Hans et al.

Ingår i Scientific Reports, 2019.

DOI för A combined gene expression tool for parallel histological prediction and gene fusion detection in non-small cell lung cancer Ladda ner fulltext (pdf) av A combined gene expression tool for parallel histological prediction and gene fusion detection in non-small cell lung cancer

Cancer stemness, intratumoral heterogeneity, and immune response across cancers

Miranda, Alex; Hamilton, Phineas T.; Zhang, Allen W.; Pattnaik, Swetansu et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 9020-9029, 2019.

DOI för Cancer stemness, intratumoral heterogeneity, and immune response across cancers

c-MET as a biomarker in patients with surgically resected non-small cell lung cancer

Tsakonas, Georgios; Botling, Johan; Micke, Patrick; Rivard, Chris et al.

Ingår i Lung Cancer, s. 69-74, 2019.

DOI för c-MET as a biomarker in patients with surgically resected non-small cell lung cancer

Immunohistochemical profiles in primary lung cancers and epithelial pulmonary metastases

Vidarsdottir, Halla; Tran, Lena; Nodin, Björn; Jirström, Karin et al.

Ingår i Human Pathology, s. 221-230, 2019.

DOI för Immunohistochemical profiles in primary lung cancers and epithelial pulmonary metastases

LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer

Cadenas, Cristina; Vosbeck, Sonja; Edlund, Karolina; Grgas, Katharina et al.

Ingår i International Journal of Cancer, s. 901-915, 2019.

DOI för LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer Ladda ner fulltext (pdf) av LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer

Mucin staining is of limited value in addition to basic immunohistochemical analyses in the diagnostics of non-small cell lung cancer

Micke, Patrick; Botling, Johan; Mattsson, Johanna Sofia Margareta; Planck, Maria et al.

Ingår i Scientific Reports, 2019.

DOI för Mucin staining is of limited value in addition to basic immunohistochemical analyses in the diagnostics of non-small cell lung cancer Ladda ner fulltext (pdf) av Mucin staining is of limited value in addition to basic immunohistochemical analyses in the diagnostics of non-small cell lung cancer

Multiplex plasma protein profiling identifies novel markers to discriminate patients with adenocarcinoma of the lung

Djureinovic, Dijana; Pontén, Victor; Landelius, Per; Al Sayegh, Sahar et al.

Ingår i BMC Cancer, 2019.

DOI för Multiplex plasma protein profiling identifies novel markers to discriminate patients with adenocarcinoma of the lung Ladda ner fulltext (pdf) av Multiplex plasma protein profiling identifies novel markers to discriminate patients with adenocarcinoma of the lung

Mutation patterns in a population-based non-small cell lung cancer cohort and prognostic impact of concomitant mutations in KRAS and TP53 or STK11

La Fleur, Linnea; Falk-Sörqvist, Elin; Smeds, Patrik; Berglund, Anders et al.

Ingår i Lung Cancer, s. 50-58, 2019.

DOI för Mutation patterns in a population-based non-small cell lung cancer cohort and prognostic impact of concomitant mutations in KRAS and TP53 or STK11 Ladda ner fulltext (pdf) av Mutation patterns in a population-based non-small cell lung cancer cohort and prognostic impact of concomitant mutations in KRAS and TP53 or STK11

NK- and T-cell subsets in malignant mesothelioma patients: Baseline pattern and changes in the context of anti-CTLA-4 therapy

Sottile, Rosa; Tannazi, Milad; Johansson, Maria H.; Cristiani, Costanza Maria et al.

Ingår i International Journal of Cancer, s. 2238-2248, 2019.

DOI för NK- and T-cell subsets in malignant mesothelioma patients: Baseline pattern and changes in the context of anti-CTLA-4 therapy

Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC

Edlund, Karolina; Madjar, Katrin; Mattsson, Johanna Sofia Margareta; Djureinovic, Dijana et al.

Ingår i Journal of Thoracic Oncology, s. 628-640, 2019.

DOI för Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC Ladda ner fulltext (pdf) av Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC

Programmed Cell Death Ligand 1 Immunohistochemistry: A Concordance Study Between Surgical Specimen, Biopsy, and Tissue Microarray

Elfving, Hedvig; Mattsson, Johanna Sofia Margareta; Lindskog, Cecilia; Backman, Max et al.

Ingår i Clinical Lung Cancer, s. 258-262.e1, 2019.

DOI för Programmed Cell Death Ligand 1 Immunohistochemistry: A Concordance Study Between Surgical Specimen, Biopsy, and Tissue Microarray

Real-world prevalence of programmed death ligand 1 expression in locally advanced or metastatic non small-cell lung cancer: The global, multicenter EXPRESS study

Dietel, M.; Savelov, N.; Salanova, R.; Micke, Patrick et al.

Ingår i Lung Cancer, s. 174-179, 2019.

DOI för Real-world prevalence of programmed death ligand 1 expression in locally advanced or metastatic non small-cell lung cancer: The global, multicenter EXPRESS study

30O Real-world prevalence of PD-L1 expression in locally advanced or metastatic non-small cell lung cancer (NSCLC): The global, multicentre EXPRESS study

Dietel, M.; Savelov, N.; Salanova, R.; Micke, Patrick et al.

Ingår i Journal of Thoracic Oncology, s. S74-S75, 2018.

DOI för 30O Real-world prevalence of PD-L1 expression in locally advanced or metastatic non-small cell lung cancer (NSCLC): The global, multicentre EXPRESS study

An Integrative Analysis of Transcriptome and Epigenome Features of ASCL1-Positive Lung Adenocarcinomas

Miyashita, Naoya; Horie, Masafumi; Suzuki, Hiroshi I.; Yoshihara, Masahito et al.

Ingår i Journal of Thoracic Oncology, s. 1676-1691, 2018.

DOI för An Integrative Analysis of Transcriptome and Epigenome Features of ASCL1-Positive Lung Adenocarcinomas

An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer

Horie, Masafumi; Miyashita, Naoya; Mattsson, Johanna Sofia Margareta; Mikami, Yu et al.

Ingår i Journal of Pathology, s. 154-165, 2018.

DOI för An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer

Comparison of Three Different TTF-1 Clones in Resected Primary Lung Cancer and Epithelial Pulmonary Metastase

Vidarsdottir, Halla; Tran, Lena; Nodin, Björn; Jirström, Karin et al.

Ingår i American Journal of Clinical Pathology, s. 533-544, 2018.

DOI för Comparison of Three Different TTF-1 Clones in Resected Primary Lung Cancer and Epithelial Pulmonary Metastase

COX-2 expression and effects of celecoxib in addition to standard chemotherapy in advanced non-small cell lung cancer.

Gulyas, Miklos; Mattsson, Johanna Sofia Margareta; Lindgren, Andrea; Ek, Lars et al.

Ingår i Acta Oncologica, s. 244-250, 2018.

DOI för COX-2 expression and effects of celecoxib in addition to standard chemotherapy in advanced non-small cell lung cancer.

Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer

Djureinovic, Dijana; Dodig-Crnkovic, Tea; Hellström, Cecilia; Holgersson, Georg et al.

Ingår i Lung Cancer, s. 157-163, 2018.

DOI för Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer

Digital multiplex immunofluorescence analysis identifies immune profiles in the tumor stroma associated with clinical outcome

Mezheyeuski, Artur; Bergsland, Christian; Backman, Max; Sjöblom, Tobias et al.

Ingår i CANCER IMMUNOLOGY RESEARCH, 2018.

DOI för Digital multiplex immunofluorescence analysis identifies immune profiles in the tumor stroma associated with clinical outcome

Digital pathology 2.0: a deep learning image analysis tool to identify lung cancer in human tissue samples

Micke, Patrick; Björk, L.; Backman, M.; Elfving, H. et al.

Ingår i Virchows Archiv, s. S106-S107, 2018.

Expression of scavenger receptor MARCO defines a targetable tumor-associated macrophage subset in non-small cell lung cancer

La Fleur, Linnea; Boura, Vanessa F.; Alexeyenko, Andrey; Berglund, Anders et al.

Ingår i International Journal of Cancer, s. 1741-1752, 2018.

DOI för Expression of scavenger receptor MARCO defines a targetable tumor-associated macrophage subset in non-small cell lung cancer

LMO7 and LIMCH1 interact with LRIG proteins in lung cancer, with prognostic implications for early-stage disease

Karlsson, Terese; Kvarnbrink, Samuel; Holmlund, Camilla; Botling, Johan et al.

Ingår i Lung Cancer, s. 174-184, 2018.

DOI för LMO7 and LIMCH1 interact with LRIG proteins in lung cancer, with prognostic implications for early-stage disease

Multispectral imaging for quantitative and compartment-specific immune infiltrates reveals distinct immune profiles that classify lung cancer patients

Mezheyeuski, Artur; Bergsland, Christian Holst; Backman, Max; Djureinovic, Dijana et al.

Ingår i Journal of Pathology, s. 421-431, 2018.

DOI för Multispectral imaging for quantitative and compartment-specific immune infiltrates reveals distinct immune profiles that classify lung cancer patients

Radionuclide Therapy of HER2-Expressing Human Xenografts Using Affibody-Based Peptide Nucleic Acid-Mediated Pretargeting: In Vivo Proof of Principle

Westerlund, Kristina; Altai, Mohamed; Mitran, Bogdan; Konijnenberg, Mark et al.

Ingår i Journal of Nuclear Medicine, s. 1092-1098, 2018.

DOI för Radionuclide Therapy of HER2-Expressing Human Xenografts Using Affibody-Based Peptide Nucleic Acid-Mediated Pretargeting: In Vivo Proof of Principle

Real-World Prevalence of PD-L1 Expression in Advanced NoneSmall-Cell Lung Cancer: The Global, Multicenter EXPRESS Study

Salanova, R.; Dietel, M.; Savelov, N.; Micke, Patrick et al.

Ingår i Journal of Thoracic Oncology, s. S155-S156, 2018.

The Heidelberg compact electron beam ion traps

Micke, Patrick; Kühn, S; Buchauer, L; Harries, J R et al.

Ingår i Review of Scientific Instruments, 2018.

DOI för The Heidelberg compact electron beam ion traps

The Role of TGF- Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis

Saito, Akira; Horie, Masafumi; Micke, Patrick; Nagase, Takahide

Ingår i International Journal of Molecular Sciences, 2018.

DOI för The Role of TGF- Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis Ladda ner fulltext (pdf) av The Role of TGF- Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis

A pathology atlas of the human cancer transcriptome

Uhlen, Mathias; Zhang, Cheng; Lee, Sunjae; Sjöstedt, Evelina et al.

Ingår i Science, 2017.

DOI för A pathology atlas of the human cancer transcriptome

Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel

Sandelin, Martin; Gruden, S.; Räsänen, Veera; Micke, Patrick et al.

Ingår i Annals of Oncology, 2017.

DOI för Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel

Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel

Grudén, Stefan; Sandelin, Martin; Rasanen, Veera; Micke, Patrick et al.

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 186-193, 2017.

DOI för Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel Ladda ner fulltext (pdf) av Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel

Establishing Reflex NGS Testing in NSCLC in a Regional Network of County Hospitals in Central Sweden

Isaksson, Johan; Willen, Linda; La Fleur, Linnea; Mindus, Stephanie et al.

Ingår i Journal of Thoracic Oncology, s. S499-S500, 2017.

DOI för Establishing Reflex NGS Testing in NSCLC in a Regional Network of County Hospitals in Central Sweden

Gene Expression Profiling of Large Cell Lung Cancer Links Transcriptional Phenotypes to the New Histological WHO 2015 Classification

Karlsson, Anna; Brunnström, Hans; Micke, Patrick; Veerla, Srinivas et al.

Ingår i Journal of Thoracic Oncology, s. 1257-1267, 2017.

DOI för Gene Expression Profiling of Large Cell Lung Cancer Links Transcriptional Phenotypes to the New Histological WHO 2015 Classification Ladda ner fulltext (pdf) av Gene Expression Profiling of Large Cell Lung Cancer Links Transcriptional Phenotypes to the New Histological WHO 2015 Classification

Integrative analysis of genome-wide gene copy number changes and gene expression in non-small cell lung cancer

Jabs, Verena; Edlund, Karolina; Koenig, Helena; Grinberg, Marianna et al.

Ingår i PLOS ONE, 2017.

DOI för Integrative analysis of genome-wide gene copy number changes and gene expression in non-small cell lung cancer Ladda ner fulltext (pdf) av Integrative analysis of genome-wide gene copy number changes and gene expression in non-small cell lung cancer

Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC

Horie, Masafumi; Kaczkowski, Bogumil; Ohshima, Mitsuhiro; Matsuzaki, Hirotaka et al.

Ingår i Molecular Cancer Research, s. 1354-1365, 2017.

DOI för Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC

Mutation Profiling by Targeted Next Generation Sequencing of an Unselected NSCLC Cohort

La Fleur, Linnea; Falk-Sörqvist, Elin; Smeds, Patrik; Sundström, Magnus et al.

Ingår i Journal of Thoracic Oncology, s. S526-S527, 2017.

DOI för Mutation Profiling by Targeted Next Generation Sequencing of an Unselected NSCLC Cohort

PD-L1 immunohistochemistry in clinical diagnostics: Inter-pathologist variability is as high as assay variability

Micke, Patrick; Johansson, Anna; Westbom-Fremer, Anna; Backman, Max et al.

Ingår i Journal of Clinical Oncology, 2017.

DOI för PD-L1 immunohistochemistry in clinical diagnostics: Inter-pathologist variability is as high as assay variability

PD-L1 immunohistochemistry in clinical diagnostics of lung cancer: inter-pathologist variability is higher than assay variability

Brunnstrom, Hans; Johansson, Anna; Westbom-Fremer, Sofia; Backman, Max et al.

Ingår i Modern Pathology, s. 1411-1421, 2017.

DOI för PD-L1 immunohistochemistry in clinical diagnostics of lung cancer: inter-pathologist variability is higher than assay variability

RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer

Rao, Shuan; Sigl, Verena; Wimmer, Reiner Alois; Novatchkova, Maria et al.

Ingår i Genes & Development, s. 2099-2112, 2017.

DOI för RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer Ladda ner fulltext (pdf) av RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer

Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters.

Grinberg, Marianna; Djureinovic, Dijana; Brunnström, Hans R R; Mattsson, Johanna Sofia Margareta et al.

Ingår i Modern Pathology, s. 964-977, 2017.

DOI för Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters.

Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer

Mathot, Lucy; Kundu, Snehangshu; Ljungström, Viktor; Svedlund, Jessica et al.

Ingår i Cancer Research, s. 1730-1740, 2017.

DOI för Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer

The clinical impact of tumour-infiltrating lymphocytes in colorectal cancer differs by anatomical subsite: A cohort study

Berntsson, Jonna; Svensson, Maria C.; Leandersson, Karin; Nodin, Bjorn et al.

Ingår i International Journal of Cancer, s. 1654-1666, 2017.

DOI för The clinical impact of tumour-infiltrating lymphocytes in colorectal cancer differs by anatomical subsite: A cohort study Ladda ner fulltext (pdf) av The clinical impact of tumour-infiltrating lymphocytes in colorectal cancer differs by anatomical subsite: A cohort study

The integrative clinical impact of tumor-infiltrating T lymphocytes and NK cells in relation to B lymphocyte and plasma cell density in esophageal and gastric adenocarcinoma

Svensson, Maria C.; Warfvinge, Carl Fredrik; Fristedt, Richard; Hedner, Charlotta et al.

Ingår i OncoTarget, s. 72108-72126, 2017.

DOI för The integrative clinical impact of tumor-infiltrating T lymphocytes and NK cells in relation to B lymphocyte and plasma cell density in esophageal and gastric adenocarcinoma Ladda ner fulltext (pdf) av The integrative clinical impact of tumor-infiltrating T lymphocytes and NK cells in relation to B lymphocyte and plasma cell density in esophageal and gastric adenocarcinoma

Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

Tanaka, Nobuyuki; Kanatani, Shigeaki; Tomer, Raju; Sahlgren, Cecilia et al.

Ingår i Nature Biomedical Engineering, s. 796-806, 2017.

DOI för Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

Epsin Family Member 3 and Ribosome-Related Genes Are Associated with Late Metastasis in Estrogen Receptor-Positive Breast Cancer and Long-Term Survival in Non-Small Cell Lung Cancer Using a Genome-Wide Identification and Validation Strategy

Hellwig, Birte; Madjar, Katrin; Edlund, Karolina; Marchan, Rosemarie et al.

Ingår i PLOS ONE, 2016.

DOI för Epsin Family Member 3 and Ribosome-Related Genes Are Associated with Late Metastasis in Estrogen Receptor-Positive Breast Cancer and Long-Term Survival in Non-Small Cell Lung Cancer Using a Genome-Wide Identification and Validation Strategy Ladda ner fulltext (pdf) av Epsin Family Member 3 and Ribosome-Related Genes Are Associated with Late Metastasis in Estrogen Receptor-Positive Breast Cancer and Long-Term Survival in Non-Small Cell Lung Cancer Using a Genome-Wide Identification and Validation Strategy

Fibroblast VEGF-receptor 1 expression as molecular target in periodontitis

Ohshima, Mitsuhiro; Yamaguchi, Yoko; Ambe, Kimiharu; Horie, Masafumi et al.

Ingår i Journal of Clinical Periodontology, s. 128-137, 2016.

DOI för Fibroblast VEGF-receptor 1 expression as molecular target in periodontitis

Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer

Mattsson, Johanna Sofia Margareta; Brunnström, Hans; Jabs, Verena; Edlund, Karolina et al.

Ingår i BMC Cancer, 2016.

DOI för Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer Ladda ner fulltext (pdf) av Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer

Profiling cancer testis antigens in non-small-cell lung cancer

Djureinovic, Dijana; Hallström, Bjorn M.; Horie, Masafumi; Mattsson, Johanna Sofia Margareta et al.

Ingår i JCI INSIGHT, 2016.

DOI för Profiling cancer testis antigens in non-small-cell lung cancer

Prognostic impact of tumor-associated B-cells and plasma cells in esophageal and gastric adenocarcinoma

Fristedt, Richard; Hedner, Charlotta; Borg, David; Nodin, Björn et al.

Ingår i Journal of Clinical Oncology, 2016.

Prognostic impact of tumour-associated B cells and plasma cells in epithelial ovarian cancer

Lundgren, Sebastian; Berntsson, Jonna; Nodin, Björn; Micke, Patrick et al.

Ingår i Journal of Ovarian Research, 2016.

DOI för Prognostic impact of tumour-associated B cells and plasma cells in epithelial ovarian cancer Ladda ner fulltext (pdf) av Prognostic impact of tumour-associated B cells and plasma cells in epithelial ovarian cancer

Prognostic impact of tumour-associated B cells and plasma cells in oesophageal and gastric adenocarcinoma

Fristedt, Richard; Borg, David; Hedner, Charlotta; Berntsson, Jonna et al.

Ingår i Journal of Gastrointestinal Oncology, s. 848-859, 2016.

DOI för Prognostic impact of tumour-associated B cells and plasma cells in oesophageal and gastric adenocarcinoma

Prognostic impact of tumour-infiltrating B cells and plasma cells in colorectal cancer

Berntsson, Jonna; Nodin, Björn; Eberhard, Jakob; Micke, Patrick et al.

Ingår i International Journal of Cancer, s. 1129-1139, 2016.

DOI för Prognostic impact of tumour-infiltrating B cells and plasma cells in colorectal cancer

The Impact of the Fourth Edition of the WHO Classification of Lung Tumours on Histological Classification of Resected Pulmonary NSCCs

Micke, Patrick; Mattsson, Johanna Sofia Margareta; Djureinovic, Dijana; Nodin, Björn et al.

Ingår i Journal of Thoracic Oncology, s. 862-872, 2016.

DOI för The Impact of the Fourth Edition of the WHO Classification of Lung Tumours on Histological Classification of Resected Pulmonary NSCCs

The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling

Raja, Erna; Tzavlaki, Kalliopi; Vuilleumier, Robin; Edlund, Karolina et al.

Ingår i OncoTarget, s. 1120-1143, 2016.

DOI för The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling Ladda ner fulltext (pdf) av The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling

Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis

Horie, Masafumi; Yamaguchi, Yoko; Saito, Akira; Nagase, Takahide et al.

Ingår i Scientific Reports, 2016.

DOI för Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis Ladda ner fulltext (pdf) av Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis

Various Antibody Clones of Napsin A, Thyroid Transcription Factor 1, and p40 and Comparisons With Cytokeratin 5 and p63 in Histopathologic Diagnostics of Non-Small Cell Lung Carcinoma

Tran, Lena; Mattsson, Johanna Sofia Margareta; Nodin, Björn; Jönsson, Per et al.

Ingår i Applied immunohistochemistry & molecular morphology (Print), s. 648-659, 2016.

DOI för Various Antibody Clones of Napsin A, Thyroid Transcription Factor 1, and p40 and Comparisons With Cytokeratin 5 and p63 in Histopathologic Diagnostics of Non-Small Cell Lung Carcinoma

ALK Rearrangements in Non-Small Cell Lung Cancer: Comprehensive Integration of Genomic, Gene Expression and Protein Analysis

Mattsson, Johanna S. M.; Svensson, Maria A.; Hallström, Björn; Koyi, Hirsh et al.

Ingår i Journal of Thoracic Oncology, s. S298-S298, 2015.

Clinical Validation of HaloPlex Targeted Resequencing in Formalin-Fixed, Paraffin-Embedded (FFPE) Cancer Biopsies

Moens, Lotte. N.; Falk-Sörqvist, Elin; La Fleur, Linnea; Mattsson, Johanna et al.

Ingår i Journal of Molecular Diagnostics, s. 822-822, 2015.

COX-2 Expression Does Not Predict Outcome of Celecoxib in Addition to Standard Chemotherapy in Advanced Non-Small Cell Lung Cancer

Gulyas, Miklos; Mattsson, Johanna S. M.; Lindgren, Andrea; Sederholm, Christer et al.

Ingår i Journal of Thoracic Oncology, s. S541-S542, 2015.

HaloPlex Targeted Resequencing for Mutation Detection in Clinical Formalin-Fixed, Paraffin-Embedded Tumor Samples

Moens, Lotte N. J.; Falk-Sörqvist, Elin; Ljungström, Viktor; Mattsson, Johanna et al.

Ingår i Journal of Molecular Diagnostics, s. 729-739, 2015.

DOI för HaloPlex Targeted Resequencing for Mutation Detection in Clinical Formalin-Fixed, Paraffin-Embedded Tumor Samples

Identification of sample annotation errors in gene expression datasets

Lohr, Miriam; Hellwig, Birte; Edlund, Karolina; Mattsson, Johanna S. M. et al.

Ingår i Archives of Toxicology, s. 2265-2272, 2015.

DOI för Identification of sample annotation errors in gene expression datasets Ladda ner fulltext (pdf) av Identification of sample annotation errors in gene expression datasets