Publikationer i DiVA – Fredrik Pontén

An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers

Mezheyeuski, Artur; Backman, Max; Mattsson, Johanna Sofia Margareta; Martin-Bernabe, Alfonso et al.

Ingår i EBioMedicine, 2023.

DOI för An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers Ladda ner fulltext (pdf) av An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers

Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β

Wegrzyniak, Olivia; Zhang, Bo; Rokka, Johanna; Rosestedt, Maria et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2023.

DOI för Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β Ladda ner fulltext (pdf) av Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β

Next generation pan-cancer blood proteome profiling using proximity extension assay

Alvez, Maria Bueno; Edfors, Fredrik; von Feilitzen, Kalle; Zwahlen, Martin et al.

Ingår i Nature Communications, 2023.

DOI för Next generation pan-cancer blood proteome profiling using proximity extension assay Ladda ner fulltext (pdf) av Next generation pan-cancer blood proteome profiling using proximity extension assay

Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer

Backman, Max; Strell, Carina; Lindberg, Amanda; Mattsson, Johanna Sofia Margareta et al.

Ingår i European Journal of Cancer, s. 40-52, 2023.

DOI för Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer Ladda ner fulltext (pdf) av Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer

A human adipose tissue cell-type transcriptome atlas

Norreen-Thorsen, Marthe; Struck, Eike Christopher; Oling, Sofia; Zwahlen, Martin et al.

Ingår i Cell reports, 2022.

DOI för A human adipose tissue cell-type transcriptome atlas Ladda ner fulltext (pdf) av A human adipose tissue cell-type transcriptome atlas

Antibody Validation for Estrogen Receptor Beta

Birgersson, Madeleine; Katona, Borbala; Lindskog, Cecilia; Pontén, Fredrik et al.

Ingår i Estrogen Receptors. Methods in Molecular Biology, s. 1-23, 2022.

DOI för Antibody Validation for Estrogen Receptor Beta

Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors

Bergman-Larsson, Julia; Gustafsson, Sofie; Méar, Loren; Huvila, Jutta et al.

Ingår i Annals of Diagnostic Pathology, 2022.

DOI för Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors Ladda ner fulltext (pdf) av Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors

Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level

Wang, Fei; Ding, Peiwen; Liang, Xue; Ding, Xiangning et al.

Ingår i Nature Communications, 2022.

DOI för Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level Ladda ner fulltext (pdf) av Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level

Genome-wide annotation of protein-coding genes in pig

Karlsson, Max; Sjöstedt, Evelina; Oksvold, Per; Sivertsson, Asa et al.

Ingår i BMC Biology, 2022.

DOI för Genome-wide annotation of protein-coding genes in pig Ladda ner fulltext (pdf) av Genome-wide annotation of protein-coding genes in pig

A single-cell type transcriptomics map of human tissues

Karlsson, Max; Zhang, Cheng; Méar, Loren; Zhong, Wen et al.

Ingår i Science Advances, 2021.

DOI för A single-cell type transcriptomics map of human tissues Ladda ner fulltext (pdf) av A single-cell type transcriptomics map of human tissues

Annotation of pituitary neuroendocrine tumors with genome-wide expression analysis

Tebani, Abdellah; Jotanovic, Jelena; Hekmati, Neda; Sivertsson, Åsa et al.

Ingår i Acta neuropathologica communications, 2021.

DOI för Annotation of pituitary neuroendocrine tumors with genome-wide expression analysis

ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.

Huang, Hua; Georganaki, Maria; Conze, Lei Liu; Laviña, Bàrbara et al.

Ingår i Neuro-Oncology, s. 398-411, 2021.

DOI för ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma. Ladda ner fulltext (pdf) av ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.

Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer

Backman, Max; La Fleur, Linnea; Kurppa, Pinja; Djureinovic, Dijana et al.

Ingår i Journal of Pathology, s. 243-256, 2021.

DOI för Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer Ladda ner fulltext (pdf) av Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer

Spatiotemporal dissection of the cell cycle with single-cell proteogenomics

Mahdessian, Diana; Cesnik, Anthony J.; Gnann, Christian; Danielsson, Frida et al.

Ingår i Nature, s. 649-654, 2021.

DOI för Spatiotemporal dissection of the cell cycle with single-cell proteogenomics

The Immune Landscape of Colorectal Cancer

Mezheyeuski, Artur; Micke, Patrick; Martin-Bernabe, Alfonso; Backman, Max et al.

Ingår i Cancers, 2021.

DOI för The Immune Landscape of Colorectal Cancer Ladda ner fulltext (pdf) av The Immune Landscape of Colorectal Cancer

The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor beta signaling

Papoutsoglou, Panagiotis; Rodrigues Junior, Dorival Mendes; Morén, Anita; Bergman, Andrew et al.

Ingår i Oncogene, s. 3748-3765, 2021.

DOI för The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor beta signaling Ladda ner fulltext (pdf) av The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor beta signaling

The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types

Micke, Patrick; Strell, Carina; Mattsson, Johanna Sofia Margareta; Martin-Bernabe, Alfonso et al.

Ingår i EBioMedicine, 2021.

DOI för The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types Ladda ner fulltext (pdf) av The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types

An atlas of the protein-coding genes in the human, pig, and mouse brain

Sjostedt, Evelina; Zhong, Wen; Fagerberg, Linn; Karlsson, Max et al.

Ingår i Science, s. 1090-+, 2020.

DOI för An atlas of the protein-coding genes in the human, pig, and mouse brain

Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy

Strandberg, Kristin; Ayoglu, Burcu; Roos, Andreas; Reza, Mojgan et al.

Ingår i JOURNAL OF NEUROMUSCULAR DISEASES, s. 231-246, 2020.

DOI för Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy Ladda ner fulltext (pdf) av Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy

CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup

Aasebo, Kristine; Dragomir, Anca; Sundström, Magnus; Mezheyeuski, Artur et al.

Ingår i Frontiers in Oncology, 2020.

DOI för CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup Ladda ner fulltext (pdf) av CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup

Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study

Mezheyeuski, Artur; Pontén, Fredrik; Edqvist, Per-Henrik D; Sundström, Magnus et al.

Ingår i Acta Oncologica, s. 284-290, 2020.

DOI för Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study Ladda ner fulltext (pdf) av Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study

Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis

Nunes, Luís; Aasebø, Kristine; Mathot, Lucy; Ljungström, Viktor et al.

Ingår i Acta Oncologica, s. 417-426, 2020.

DOI för Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis Ladda ner fulltext (pdf) av Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis

Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues

Lindskog, Cecilia; Backman, Max; Zieba, Agata; Asplund, Anna et al.

Ingår i Journal of Histochemistry and Cytochemistry, s. 515-529, 2020.

DOI för Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues

A deep proteome and transcriptome abundance atlas of 29 healthy human tissues

Wang, Dongxue; Eraslan, Basak; Wieland, Thomas; Hallstrom, Bjorn et al.

Ingår i Molecular Systems Biology, 2019.

DOI för A deep proteome and transcriptome abundance atlas of 29 healthy human tissues Ladda ner fulltext (pdf) av A deep proteome and transcriptome abundance atlas of 29 healthy human tissues

A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

Uhlen, Mathias; Karlsson, Max J.; Zhong, Wen; Tebani, Abdellah et al.

Ingår i Science, s. 1471-+, 2019.

DOI för A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients

Aasebö, Kristine Ö.; Dragomir, Anca; Sundström, Magnus; Mezheyeuski, Artur et al.

Ingår i Cancer Medicine, s. 3623-3635, 2019.

DOI för Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients Ladda ner fulltext (pdf) av Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients

LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer

Cadenas, Cristina; Vosbeck, Sonja; Edlund, Karolina; Grgas, Katharina et al.

Ingår i International Journal of Cancer, s. 901-915, 2019.

DOI för LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer Ladda ner fulltext (pdf) av LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer

Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC

Edlund, Karolina; Madjar, Katrin; Mattsson, Johanna Sofia Margareta; Djureinovic, Dijana et al.

Ingår i Journal of Thoracic Oncology, s. 628-640, 2019.

DOI för Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC Ladda ner fulltext (pdf) av Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC

Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues

Eraslan, Basak; Wang, Dongxue; Gusic, Mirjana; Prokisch, Holger et al.

Ingår i Molecular Systems Biology, 2019.

DOI för Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues Ladda ner fulltext (pdf) av Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues

Stroma-normalised vessel density predicts benefit from adjuvant fluorouracil-based chemotherapy in patients with stage II/III colon cancer

Mezheyeuski, Artur; Hrynchyk, Ina; Herrera, Mercedes; Karlberg, Mia et al.

Ingår i British Journal of Cancer, s. 303-311, 2019.

DOI för Stroma-normalised vessel density predicts benefit from adjuvant fluorouracil-based chemotherapy in patients with stage II/III colon cancer

Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles

Fredolini, Claudia; Byström, Sanna; Sanchez-Rivera, Laura; Ioannou, Marina et al.

Ingår i Scientific Reports, 2019.

DOI för Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles Ladda ner fulltext (pdf) av Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles

The human secretome

Uhlen, Mathias; Karlsson, Max J.; Hober, Andreas; Svensson, Anne-Sophie et al.

Ingår i Science Signaling, 2019.

DOI för The human secretome

Tumoral pyruvate kinase L/R as a predictive marker for the treatment of renal cancer patients with sunitinib and sorafenib

Niinivirta, Marjut; Enblad, Gunilla; Lindskog, Cecilia; Pontén, Fredrik et al.

Ingår i Journal of Cancer, s. 3224-3231, 2019.

DOI för Tumoral pyruvate kinase L/R as a predictive marker for the treatment of renal cancer patients with sunitinib and sorafenib Ladda ner fulltext (pdf) av Tumoral pyruvate kinase L/R as a predictive marker for the treatment of renal cancer patients with sunitinib and sorafenib

Combined ASRGL1 and p53 immunohistochemistry as an independent predictor of survival in endometrioid endometrial carcinoma

Huvila, Jutta; Laajala, Teemu D.; Edqvist, Per-Henrik D; Mardinoglu, Adil et al.

Ingår i Gynecologic Oncology, s. 173-180, 2018.

DOI för Combined ASRGL1 and p53 immunohistochemistry as an independent predictor of survival in endometrioid endometrial carcinoma

Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer

Djureinovic, Dijana; Dodig-Crnkovic, Tea; Hellström, Cecilia; Holgersson, Georg et al.

Ingår i Lung Cancer, s. 157-163, 2018.

DOI för Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer

Immunohistochemistry for transcription factor T-Pit as a tool in diagnostics of corticotroph pituitary tumours

Casar Borota, Olivera; Bollerslev, Jens; Pontén, Fredrik

Ingår i Pituitary, s. 443-443, 2018.

DOI för Immunohistochemistry for transcription factor T-Pit as a tool in diagnostics of corticotroph pituitary tumours

In situ protein detection with enhanced specificity using DNA-conjugated antibodies and proximity ligation

Zieba, Agata; Ponten, Fredrik; Uhlen, Mathias; Landegren, Ulf

Ingår i Modern Pathology, s. 253-263, 2018.

DOI för In situ protein detection with enhanced specificity using DNA-conjugated antibodies and proximity ligation

Mining the Human Tissue Proteome for Protein Citrullination

Lee, Chien-Yun; Wang, Dongxue; Wilhelm, Mathias; Zolg, Daniel P. et al.

Ingår i Molecular & Cellular Proteomics, s. 1378-1391, 2018.

DOI för Mining the Human Tissue Proteome for Protein Citrullination

Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage

Matic, Ljubica Perisic; Iglesias, Maria Jesus; Vesterlund, Mattias; Lengquist, Mariette et al.

Ingår i JACC-BASIC TO TRANSLATIONAL SCIENCE, s. 464-480, 2018.

DOI för Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage Ladda ner fulltext (pdf) av Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage

U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Glimelius, Bengt; Melin, Beatrice; Enblad, Gunilla; Alafuzoff, Irina et al.

Ingår i Acta Oncologica, s. 187-194, 2018.

DOI för U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden. Ladda ner fulltext (pdf) av U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

A nonsense mutation in CEP55 defines a new locus for a Meckel-like syndrome, an autosomal recessive lethal fetal ciliopathy.

Bondeson, Marie-Louise; Ericson, Katharina; Gudmundsson, Sanna; Ameur, Adam et al.

Ingår i Clinical Genetics, s. 510-516, 2017.

DOI för A nonsense mutation in CEP55 defines a new locus for a Meckel-like syndrome, an autosomal recessive lethal fetal ciliopathy.

A pathology atlas of the human cancer transcriptome

Uhlen, Mathias; Zhang, Cheng; Lee, Sunjae; Sjöstedt, Evelina et al.

Ingår i Science, 2017.

DOI för A pathology atlas of the human cancer transcriptome

A specific antibody to detect transcription factor T-Pit: a reliable marker of corticotroph cell differentiation and a tool to improve the classification of pituitary neuroendocrine tumours

Sjöstedt, Evelina; Bollerslev, Jens; Mulder, Jan; Lindskog, Cecilia et al.

Ingår i Acta Neuropathologica, s. 675-677, 2017.

DOI för A specific antibody to detect transcription factor T-Pit: a reliable marker of corticotroph cell differentiation and a tool to improve the classification of pituitary neuroendocrine tumours

A subcellular map of the human proteome

Thul, Peter J.; åkesson, Lovisa; Wiking, Mikaela; Mahdessian, Diana et al.

Ingår i Science, 2017.

DOI för A subcellular map of the human proteome

A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma

Gremel, Gabriela; Djureinovic, Dijana; Niinivirta, Marjut; Laird, Alexander et al.

Ingår i BMC Cancer, 2017.

DOI för A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma Ladda ner fulltext (pdf) av A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma

Affinity Proteomics Exploration of Melanoma Identifies Proteins in Serum with Associations to T-Stage and Recurrence

Byström, Sanna; Fredolini, Claudia; Edqvist, Per-Henrik D; Nyaiesh, Etienne-Nicholas et al.

Ingår i Translational Oncology, s. 385-395, 2017.

DOI för Affinity Proteomics Exploration of Melanoma Identifies Proteins in Serum with Associations to T-Stage and Recurrence

Breast cancer in young women and prognosis: How important are proliferation markers?

Fredholm, Hanna; Magnusson, Kristina; Lindstrom, Linda S.; Tobin, Nicholas P. et al.

Ingår i European Journal of Cancer, s. 278-289, 2017.

DOI för Breast cancer in young women and prognosis: How important are proliferation markers?

Cetuximab sensitivity of head and neck squamous cell carcinoma xenografts is associated with treatment-induced reduction in EGFR, pEGFR, and pSrc.

Jedlinski, Adam; Garvin, Stina; Johansson, Ann-Charlotte; Edqvist, Per-Henrik D et al.

Ingår i Journal of Oral Pathology & Medicine, s. 717-724, 2017.

DOI för Cetuximab sensitivity of head and neck squamous cell carcinoma xenografts is associated with treatment-induced reduction in EGFR, pEGFR, and pSrc.

High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer

Siesing, Christina; Sorbye, Halfdan; Dragomir, Anca; Pfeiffer, Per et al.

Ingår i PLOS ONE, 2017.

DOI för High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer Ladda ner fulltext (pdf) av High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer

Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential

Roy, Ananya; Libard, Sylwia; Weishaupt, Holger; Gustavsson, Ida et al.

Ingår i Frontiers in Oncology, 2017.

DOI för Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential Ladda ner fulltext (pdf) av Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential

Principles of Systems Biology, No. 21: Editorial

Cao, Junyue; Packer, Jonathan; Waterston, Robert; Trapnell, Cole et al.

Ingår i CELL SYSTEMS, s. 158-160, 2017.

DOI för Principles of Systems Biology, No. 21: Editorial

Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters.

Grinberg, Marianna; Djureinovic, Dijana; Brunnström, Hans R R; Mattsson, Johanna Sofia Margareta et al.

Ingår i Modern Pathology, s. 964-977, 2017.

DOI för Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters.

Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression

Roy, Ananya; Attarha, Sanaz; Weishaupt, Holger; Edqvist, Per-Henrik et al.

Ingår i OncoTarget, s. 24815-24827, 2017.

DOI för Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression Ladda ner fulltext (pdf) av Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression

Serotonin, ATRX, and DAXX Expression in Pituitary Adenomas: Markers in the Differential Diagnosis of Neuroendocrine Tumors of the Sellar Region.

Casar Borota, Olivera; Botling, Johan; Granberg, Dan; Stigare, Jerker et al.

Ingår i American Journal of Surgical Pathology, s. 1238-1246, 2017.

DOI för Serotonin, ATRX, and DAXX Expression in Pituitary Adenomas: Markers in the Differential Diagnosis of Neuroendocrine Tumors of the Sellar Region.

The human adrenal gland proteome defined by transcriptomics and antibody-based profiling

Bergman, Julia; Botling, Johan; Fagerberg, Linn; Hallström, Björn M. et al.

Ingår i Endocrinology, s. 239-251, 2017.

DOI för The human adrenal gland proteome defined by transcriptomics and antibody-based profiling

Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients

Niinivirta, Marjut; Enblad, Gunilla; Edqvist, Per-Henrik D; Pontén, Fredrik et al.

Ingår i Journal of Cancer, s. 3975-3983, 2017.

DOI för Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients Ladda ner fulltext (pdf) av Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients

Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib

Niinivirta, Marjut; Enblad, Gunilla; Edqvist, Per-Henrik; Pontén, Fredrik et al.

Ingår i Journal of Cancer Research and Clinical Oncology, s. 961-970, 2017.

DOI för Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib Ladda ner fulltext (pdf) av Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib

A stromal cell population in the large intestine identified by tissue factor expression that is lost during colorectal cancer progression

Eriksson, Oskar; Asplund, Anna; Hegde, Geeta; Edqvist, Per-Henrik D et al.

Ingår i Thrombosis and Haemostasis, s. 1050-1059, 2016.

DOI för A stromal cell population in the large intestine identified by tissue factor expression that is lost during colorectal cancer progression

Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome.

Butler, Lynn Marie; Hallström, Björn Mikael; Fagerberg, Linn; Pontén, Fredrik C et al.

Ingår i Cell systems, s. 287-301.e3, 2016.

DOI för Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome.

ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer

Magnusson, Kristina; Gremel, Gabriela; Rydén, Lisa; Pontén, Victor et al.

Ingår i BMC Cancer, 2016.

DOI för ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer Ladda ner fulltext (pdf) av ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer

Extension of diffuse low-grade gliomas beyond radiological borders as shown by the coregistration of histopathological and magnetic resonance imaging data

Zetterling, Maria; Roodakker, Kenney Roy; Berntsson, Shala Ghaderi; Edqvist, Per-Henrik D et al.

Ingår i Journal of Neurosurgery, s. 1155-1166, 2016.

DOI för Extension of diffuse low-grade gliomas beyond radiological borders as shown by the coregistration of histopathological and magnetic resonance imaging data

Gene-specific correlation of RNA and protein levels in human cells and tissues

Edfors, Fredrik; Danielsson, Frida; Hallström, Björn M.; Käll, Lukas et al.

Ingår i Molecular Systems Biology, 2016.

DOI för Gene-specific correlation of RNA and protein levels in human cells and tissues Ladda ner fulltext (pdf) av Gene-specific correlation of RNA and protein levels in human cells and tissues

GPR44 is a pancreatic protein restricted to the human beta cell

Hellström-Lindahl, Ewa; Danielsson, Angelika; Pontén, Fredrik; Czernichow, Paul et al.

Ingår i Acta Diabetologica, s. 413-421, 2016.

DOI för GPR44 is a pancreatic protein restricted to the human beta cell

Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages

Wallerius, Majken; Wallmann, Tatjana; Bartish, Margarita; Ostling, Jeanette et al.

Ingår i Cancer Research, s. 3166-3178, 2016.

DOI för Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages

Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer

Mattsson, Johanna Sofia Margareta; Brunnström, Hans; Jabs, Verena; Edlund, Karolina et al.

Ingår i BMC Cancer, 2016.

DOI för Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer Ladda ner fulltext (pdf) av Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer

Long-term outcome in young women with breast cancer: a population-based study

Fredholm, Hanna; Magnusson, Kristina; Lindström, Linda S.; Garmo, Hans et al.

Ingår i Breast Cancer Research and Treatment, s. 131-143, 2016.

DOI för Long-term outcome in young women with breast cancer: a population-based study Ladda ner fulltext (pdf) av Long-term outcome in young women with breast cancer: a population-based study

Oncogene-Induced Senescence in Pituitary Adenomas-an Immunohistochemical Study.

Manojlovic-Gacic, Emilija; Skender-Gazibara, Milica; Popovic, Vera; Soldatovic, Ivan et al.

Ingår i Endocrine pathology, s. 1-11, 2016.

DOI för Oncogene-Induced Senescence in Pituitary Adenomas-an Immunohistochemical Study.

Profiling cancer testis antigens in non-small-cell lung cancer

Djureinovic, Dijana; Hallström, Bjorn M.; Horie, Masafumi; Mattsson, Johanna Sofia Margareta et al.

Ingår i JCI INSIGHT, 2016.

DOI för Profiling cancer testis antigens in non-small-cell lung cancer

PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.

Roodakker, Kenney R.; Elsir, Tamador; Edqvist, Per-Henrik D; Hägerstrand, Daniel et al.

Ingår i OncoTarget, s. 72431-72442, 2016.

DOI för PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status. Ladda ner fulltext (pdf) av PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.

SATB2 is expressed in Merkel cell carcinoma

Fukuhara, Mari; Agnarsdottir, Margret; Edqvist, Per-Henrik; Coter, Anna et al.

Ingår i Archives of Dermatological Research, s. 449-454, 2016.

DOI för SATB2 is expressed in Merkel cell carcinoma

Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer

Mezheyeuski, Artur; Lindh, Maja Bradic; Guren, Tormod Kyrre; Dragomir, Anca et al.

Ingår i OncoTarget, s. 41948-41958, 2016.

DOI för Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer

System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis

Pozniak, Yair; Balint-Lahat, Nora; Rudolph, Jan Daniel; Lindskog, Cecilia et al.

Ingår i CELL SYSTEMS, s. 172-184, 2016.

DOI för System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis

The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene

van Kempen, Leon C. L.; Redpath, Margaret; Elchebly, Mounib; Klein, Kathleen Oros et al.

Ingår i Science Translational Medicine, 2016.

DOI för The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene

Transcriptomics resources of human tissues and organs

Uhlen, Mathias; Hallstrom, Bjorn M.; Lindskog Bergström, Cecilia; Mardinoglu, Adil et al.

Ingår i Molecular Systems Biology, 2016.

DOI för Transcriptomics resources of human tissues and organs Ladda ner fulltext (pdf) av Transcriptomics resources of human tissues and organs

Visualization and analysis of gene expression in tissue sections by spatial transcriptomics

Stahl, Patrik L.; Salmen, Fredrik; Vickovic, Sanja; Lundmark, Anna et al.

Ingår i Science, s. 78-82, 2016.

DOI för Visualization and analysis of gene expression in tissue sections by spatial transcriptomics

A prognosis based classification of undifferentiated uterine sarcomas: Identification of mitotic index, hormone receptors and YWHAE-FAM22 translocation status as predictors of survival

Gremel, Gabriela; Liew, Markus; Hamzei, Farzaneh; Hardell, Elin et al.

Ingår i International Journal of Cancer, s. 1608-1618, 2015.

DOI för A prognosis based classification of undifferentiated uterine sarcomas: Identification of mitotic index, hormone receptors and YWHAE-FAM22 translocation status as predictors of survival

A Tissue-Based Map of the Human Proteome

Pontén, Fredrik

Ingår i Scandinavian Journal of Immunology, s. 329-329, 2015.

ALK Rearrangements in Non-Small Cell Lung Cancer: Comprehensive Integration of Genomic, Gene Expression and Protein Analysis

Mattsson, Johanna S. M.; Svensson, Maria A.; Hallström, Björn; Koyi, Hirsh et al.

Ingår i Journal of Thoracic Oncology, s. S298-S298, 2015.

Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer

O'Hurley, Gillian; Busch, Christer; Fagerberg, Linn; Hallstrom, Bjorn M. et al.

Ingår i PLOS ONE, 2015.

DOI för Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer Ladda ner fulltext (pdf) av Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer

Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium

Yu, Nancy Yiu-Lin; Hallstrom, Bjorn M.; Fagerberg, Linn; Pontén, Fredrik et al.

Ingår i Nucleic Acids Research, s. 6787-6798, 2015.

DOI för Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium Ladda ner fulltext (pdf) av Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium

Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex

Sjöstedt, Evelina; Fagerberg, Linn; Hallstrom, Bjorn M.; Haggmark, Anna et al.

Ingår i PLOS ONE, 2015.

DOI för Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex Ladda ner fulltext (pdf) av Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex

Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Langenkamp, Elise; Zhang, Lei; Lugano, Roberta; Huang, Hua et al.

Ingår i Cancer Research, s. 4504-4516, 2015.

DOI för Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

Vizoso, Miguel; Ferreira, Humberto J.; Lopez-Serra, Paula; Javier Carmona, F. et al.

Ingår i Nature Medicine, s. 741-+, 2015.

DOI för Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

Expression of Human Skin-Specific Genes Defined by Transcriptomics and Antibody-Based Profiling

Edqvist, Per-Henrik D; Fagerberg, Linn; Hallström, Björn M; Danielsson, Angelika et al.

Ingår i Journal of Histochemistry and Cytochemistry, s. 129-141, 2015.

DOI för Expression of Human Skin-Specific Genes Defined by Transcriptomics and Antibody-Based Profiling

FGF2 as a potential prognostic biomarker for proneural glioma patients

Sooman, Linda; Freyhult, Eva; Jaiswal, Archita; Navani, Sanjay et al.

Ingår i Acta Oncologica, s. 385-394, 2015.

DOI för FGF2 as a potential prognostic biomarker for proneural glioma patients

Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier

Reyahi, Azadeh; Nik, Ali M.; Ghiami, Mozhgan; Gritli-Linde, Amel et al.

Ingår i Developmental Cell, s. 19-32, 2015.

DOI för Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier

Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells

Roy, Ananya; Coum, Antoine; Marinescu, Voichita D; Põlajeva, Jelena et al.

Ingår i OncoTarget, s. 23647-23661, 2015.

DOI för Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells Ladda ner fulltext (pdf) av Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells

High BRAF Mutation Frequency and Marked Survival Differences in Subgroups According to KRAS/BRAF Mutation Status and Tumor Tissue Availability in a Prospective Population-Based Metastatic Colorectal Cancer Cohort

Sorbye, Halfdan; Dragomir, Anca; Sundström, Magnus; Pfeiffer, Per et al.

Ingår i PLOS ONE, 2015.

DOI för High BRAF Mutation Frequency and Marked Survival Differences in Subgroups According to KRAS/BRAF Mutation Status and Tumor Tissue Availability in a Prospective Population-Based Metastatic Colorectal Cancer Cohort

High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes

Dijksterhuis, Jacomijn P.; Arthofer, Elisa; Marinescu, Voichita D.; Nelander, Sven et al.

Ingår i Experimental Cell Research, s. 280-288, 2015.

DOI för High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes

Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma

Edqvist, Per-Henrik D.; Huvila, Jutta; Forsstrom, Bjorn; Talve, Lauri et al.

Ingår i Gynecologic Oncology, s. 529-537, 2015.

DOI för Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Zhang, Lei; Kundu, Soumi; Feenstra, Tjerk; Li, Xiujuan et al.

Ingår i Science Signaling, 2015.

DOI för Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Prognostic impact of COX-2 in non-small cell lung cancer: A comprehensive compartment-specific evaluation of tumor and stromal cell expression

Mattsson, Johanna Sofia Margareta; Bergman, Bengt; Grinberg, Marianna; Edlund, Karolina et al.

Ingår i Cancer Letters, s. 837-845, 2015.

DOI för Prognostic impact of COX-2 in non-small cell lung cancer: A comprehensive compartment-specific evaluation of tumor and stromal cell expression

The Crux of Molecular Prognostications in NSCLC: An Optimized Biomarker Panel Fails to Outperform Clinical Parameters

Djureinovic, Dijana; Grinberg, Marianna; Mattsson, Johanna Sofia Margareta; Edlund, Karolina et al.

Ingår i Journal of Thoracic Oncology, s. S712-S713, 2015.

The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling

Lindskog, Cecilia; Linné, Jerker; Fagerberg, Linn; Hallstrom, Bjorn M. et al.

Ingår i BMC Genomics, 2015.

DOI för The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling Ladda ner fulltext (pdf) av The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling

The Human Endometrium-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling

Zieba, Agata; Sjöstedt, Evelina; Olovsson, Matts; Fagerberg, Linn et al.

Ingår i Omics, s. 659-668, 2015.

DOI för The Human Endometrium-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling

The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling.

Gremel, Gabriela; Wanders, Alkwin; Cedernaes, Jonathan; Fagerberg, Linn et al.

Ingår i Journal of gastroenterology, s. 46-57, 2015.

DOI för The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling.

The Identification of Therapeutic Targets in Lung Cancer Based on Transcriptomic and Proteomic Characterization of Cancer-Testis Antigens

Djureinovic, Dijana; Hallström, Björn; Mattsson, Johanna Sofia Margareta; La Fleur, Linnea et al.

Ingår i Journal of Thoracic Oncology, s. S256-S256, 2015.

The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling

Habuka, Masato; Fagerberg, Linn; Hallström, Björn M.; Pontén, Fredrik et al.

Ingår i PLOS ONE, 2015.

DOI för The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling Ladda ner fulltext (pdf) av The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling

Tissue-based map of the human proteome

Uhlen, Mathias; Fagerberg, Linn; Hallstroem, Bjoern M.; Lindskog, Cecilia et al.

Ingår i Science, s. 394-+, 2015.

DOI för Tissue-based map of the human proteome

Tumor Vessel Up-Regulation of INSR Revealed by Single-Cell Expression Analysis of the Tyrosine Kinome and Phosphatome in Human Cancers

Kiflemariam, Sara; Ljungström, Viktor; Pontén, Fredrik; Sjöblom, Tobias

Ingår i American Journal of Pathology, s. 1600-1609, 2015.

DOI för Tumor Vessel Up-Regulation of INSR Revealed by Single-Cell Expression Analysis of the Tyrosine Kinome and Phosphatome in Human Cancers