Publikationer i DiVA – Claes Wadelius

Machine Learning-Based Analysis of Glioma Grades Reveals Co-Enrichment

Garbulowski, Mateusz; Smolinska Garbulowska, Karolina; Cabuk, Ugur; Younes, Sara et al.

Ingår i Cancers, 2022.

DOI för Machine Learning-Based Analysis of Glioma Grades Reveals Co-Enrichment Ladda ner fulltext (pdf) av Machine Learning-Based Analysis of Glioma Grades Reveals Co-Enrichment

Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

Diamanti, Klev; Cavalli, Marco; Pereira, Maria J.; Pan, Gang et al.

Ingår i Cell Reports Medicine, 2022.

DOI för Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues Ladda ner fulltext (pdf) av Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation

Raine, Amanda; Lundmark, Anders; Annett, Alva; Wiman, Ann-Christin et al.

Ingår i Scientific Reports, 2022.

DOI för scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation Ladda ner fulltext (pdf) av scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation

Functional annotation of noncoding mutations in cancer

Umer, Husen Muhammad; Smolinska, Karolina; Komorowski, Jan; Wadelius, Claes

Ingår i Life Science Alliance, 2021.

DOI för Functional annotation of noncoding mutations in cancer Ladda ner fulltext (pdf) av Functional annotation of noncoding mutations in cancer

Genome-wide association study of liver enzyme elevation in rheumatoid arthritis patients starting methotrexate

Karlsson Sundbaum, Johanna; Baecklund, Eva; Eriksson, Niclas; Kohnke, Hugo et al.

Ingår i Pharmacogenomics (London), s. 973-982, 2021.

DOI för Genome-wide association study of liver enzyme elevation in rheumatoid arthritis patients starting methotrexate Ladda ner fulltext (pdf) av Genome-wide association study of liver enzyme elevation in rheumatoid arthritis patients starting methotrexate

Multifaceted regulation of hepatic lipid metabolism by YY1

Pan, Gang; Diamanti, Klev; Cavalli, Marco; Gutierrez, Ariadna Lara et al.

Ingår i Life Science Alliance, 2021.

DOI för Multifaceted regulation of hepatic lipid metabolism by YY1 Ladda ner fulltext (pdf) av Multifaceted regulation of hepatic lipid metabolism by YY1

Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding

Pan, Gang; Cavalli, Marco; Wadelius, Claes

Ingår i Biochimica et Biophysica Acta. Gene Regulatory Mechanisms, 2021.

DOI för Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding Ladda ner fulltext (pdf) av Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding

Single nucleus transcriptomics data integration recapitulates the major cell types in human liver

Diamanti, Klev; Inda Díaz, Juan Salvador; Raine, Amanda; Pan, Gang et al.

Ingår i Hepatology Research, s. 233-238, 2021.

DOI för Single nucleus transcriptomics data integration recapitulates the major cell types in human liver Ladda ner fulltext (pdf) av Single nucleus transcriptomics data integration recapitulates the major cell types in human liver

The Thioesterase ACOT1 as a Regulator of Lipid Metabolism in Type 2 Diabetes Detected in a Multi-Omics Study of Human Liver

Cavalli, Marco; Diamanti, Klev; Dang, Yonglong; Xing, Pengwei et al.

Ingår i Omics, s. 652-659, 2021.

DOI för The Thioesterase ACOT1 as a Regulator of Lipid Metabolism in Type 2 Diabetes Detected in a Multi-Omics Study of Human Liver Ladda ner fulltext (pdf) av The Thioesterase ACOT1 as a Regulator of Lipid Metabolism in Type 2 Diabetes Detected in a Multi-Omics Study of Human Liver

A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver

Cavalli, Marco; Diamanti, Klev; Pan, Gang; Spalinskas, Rapolas et al.

Ingår i Omics, s. 180-194, 2020.

DOI för A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver Ladda ner fulltext (pdf) av A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Rheinbay, Esther; Nielsen, Morten Muhlig; Abascal, Federico; Wala, Jeremiah A. et al.

Ingår i Nature, s. 102-111, 2020.

DOI för Analyses of non-coding somatic drivers in 2,658 cancer whole genomes Ladda ner fulltext (pdf) av Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Carlevaro-Fita, Joana; Lanzos, Andres; Feuerbach, Lars; Hong, Chen et al.

Ingår i Communications Biology, 2020.

DOI för Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis Ladda ner fulltext (pdf) av Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Combined burden and functional impact tests for cancer driver discovery using DriverPower

Shuai, Shimin; Gallinger, Steven; Stein, Lincoln

Ingår i Nature Communications, 2020.

DOI för Combined burden and functional impact tests for cancer driver discovery using DriverPower Ladda ner fulltext (pdf) av Combined burden and functional impact tests for cancer driver discovery using DriverPower

Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment.

Rasmussen, Eva Rye; Hallberg, Pär; Baranova, Ekaterina V; Eriksson, Niclas et al.

Ingår i The Pharmacogenomics Journal, s. 770-783, 2020.

DOI för Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment. Ladda ner fulltext (pdf) av Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment.

Integration of whole-body [¹⁸F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes

Diamanti, Klev; Visvanathar, Robin; Pereira, Maria J.; Cavalli, Marco et al.

Ingår i Scientific Reports, 2020.

DOI för Integration of whole-body [¹⁸F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes Ladda ner fulltext (pdf) av Integration of whole-body [¹⁸F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes

Integrative pathway enrichment analysis of multivariate omics data.

Paczkowska, Marta; Barenboim, Jonathan; Sintupisut, Nardnisa; Fox, Natalie S et al.

Ingår i Nature Communications, 2020.

DOI för Integrative pathway enrichment analysis of multivariate omics data.

Pan-cancer analysis of whole genomes

Campbell, Peter J.; Diamanti, Klev; Komorowski, Jan; Umer, Husen Muhammad et al.

Ingår i Nature, s. 82-93, 2020.

DOI för Pan-cancer analysis of whole genomes Ladda ner fulltext (pdf) av Pan-cancer analysis of whole genomes

Pathway and network analysis of more than 2500 whole cancer genomes.

Reyna, Matthew A; Haan, David; Paczkowska, Marta; Verbeke, Lieven P C et al.

Ingår i Nature Communications, 2020.

DOI för Pathway and network analysis of more than 2500 whole cancer genomes. Ladda ner fulltext (pdf) av Pathway and network analysis of more than 2500 whole cancer genomes.

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.

Bailey, Matthew H; Meyerson, William U; Dursi, Lewis Jonathan; Wang, Liang-Bo et al.

Ingår i Nature Communications, 2020.

DOI för Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples. Ladda ner fulltext (pdf) av Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.

rs953413 Regulates Polyunsaturated Fatty Acid Metabolism by Modulating ELOVL2 Expression

Pan, Gang; Cavalli, Marco; Carlsson, Björn; Skrtic, Stanko et al.

Ingår i iScience, 2020.

DOI för rs953413 Regulates Polyunsaturated Fatty Acid Metabolism by Modulating ELOVL2 Expression Ladda ner fulltext (pdf) av rs953413 Regulates Polyunsaturated Fatty Acid Metabolism by Modulating ELOVL2 Expression

Sex differences in oncogenic mutational processes.

Li, Constance H; Prokopec, Stephenie D; Sun, Ren X; Yousif, Fouad et al.

Ingår i Nature Communications, 2020.

DOI för Sex differences in oncogenic mutational processes.

Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases

Cavalli, Marco; Baltzer, Nicholas; Umer, Husen Muhammad; Grau, Jan et al.

Ingår i Scientific Reports, 2019.

DOI för Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases Ladda ner fulltext (pdf) av Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases

Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease.

Karlsson, Torgny; Rask-Andersen, Mathias; Pan, Gang; Höglund, Julia et al.

Ingår i Nature Medicine, s. 1390-1395, 2019.

DOI för Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease.

Detailed Functional Characterization of a Waist-Hip Ratio Locus in 7p15.2 Defines an Enhancer Controlling Adipocyte Differentiation

Castillejo-Lopez, Casimiro; Pjanic, Milos; Pirona, Anna Chiara; Hetty, Susanne et al.

Ingår i iScience, s. 42-59, 2019.

DOI för Detailed Functional Characterization of a Waist-Hip Ratio Locus in 7p15.2 Defines an Enhancer Controlling Adipocyte Differentiation Ladda ner fulltext (pdf) av Detailed Functional Characterization of a Waist-Hip Ratio Locus in 7p15.2 Defines an Enhancer Controlling Adipocyte Differentiation

Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes

Diamanti, Klev; Cavalli, Marco; Pan, Gang; Pereira, Maria J et al.

Ingår i Scientific Reports, 2019.

DOI för Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes Ladda ner fulltext (pdf) av Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes

Pandemrix-induced narcolepsy is associated with genes related to immunity and neuronal survival

Hallberg, Pär; Smedje, Hans; Eriksson, Niclas; Kohnke, Hugo et al.

Ingår i EBioMedicine, s. 595-604, 2019.

DOI för Pandemrix-induced narcolepsy is associated with genes related to immunity and neuronal survival Ladda ner fulltext (pdf) av Pandemrix-induced narcolepsy is associated with genes related to immunity and neuronal survival

Studies of liver tissue identify functional gene regulatory elements associated to gene expression, type 2 diabetes, and other metabolic diseases

Cavalli, Marco; Baltzer, Nicholas; Pan, Gang; Walls, Jose Ramon Barcenas et al.

Ingår i Human Genomics, 2019.

DOI för Studies of liver tissue identify functional gene regulatory elements associated to gene expression, type 2 diabetes, and other metabolic diseases Ladda ner fulltext (pdf) av Studies of liver tissue identify functional gene regulatory elements associated to gene expression, type 2 diabetes, and other metabolic diseases

Genetic prevention of hepatitis C virus-induced liver fibrosis by allele-specific downregulation of MERTK

Cavalli, Marco; Pan, Gang; Nord, Helena; Wallén Arzt, Emelie et al.

Ingår i Hepatology Research, s. 826-830, 2017.

DOI för Genetic prevention of hepatitis C virus-induced liver fibrosis by allele-specific downregulation of MERTK

Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population

Hallberg, Pär; Persson, Matilda; Axelsson, Tomas; Cavalli, Marco et al.

Ingår i Pharmacogenomics (London), s. 201-213, 2017.

DOI för Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population Ladda ner fulltext (pdf) av Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population

PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c

Pan, Gang; Ameur, Adam; Enroth, Stefan; Bysani, Madhusudhan et al.

Ingår i Nucleic Acids Research, s. 2408-2422, 2017.

DOI för PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c

A Significant Regulatory Mutation Burden at a High-Affinity Position of the CTCF Motif in Gastrointestinal Cancers

Umer, Husen M.; Cavalli, Marco; Dabrowski, Michal J.; Diamanti, Klev et al.

Ingår i Human Mutation, s. 904-913, 2016.

DOI för A Significant Regulatory Mutation Burden at a High-Affinity Position of the CTCF Motif in Gastrointestinal Cancers

Allele-specific transcription factor binding in liver and cervix cells unveils many likely drivers of GWAS signals

Cavalli, Marco; Pan, Gang; Nord, Helena; Arzt, Emelie Wallén et al.

Ingår i Genomics, s. 248-254, 2016.

DOI för Allele-specific transcription factor binding in liver and cervix cells unveils many likely drivers of GWAS signals Ladda ner fulltext (pdf) av Allele-specific transcription factor binding in liver and cervix cells unveils many likely drivers of GWAS signals

Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression

Cavalli, Marco; Pan, Gang; Nord, Helena; Wallerman, Ola et al.

Ingår i Human Genetics, s. 485-497, 2016.

DOI för Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression Ladda ner fulltext (pdf) av Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression

Genetic determinants of warfarin maintenance dose and time in therapeutic treatment range: a RE-LY genomics substudy

Eriksson, Niclas; Wallentin, Lars; Berglund, Lars; Axelsson, Tomas et al.

Ingår i Pharmacogenomics (London), s. 1425-1439, 2016.

DOI för Genetic determinants of warfarin maintenance dose and time in therapeutic treatment range: a RE-LY genomics substudy Ladda ner fulltext (pdf) av Genetic determinants of warfarin maintenance dose and time in therapeutic treatment range: a RE-LY genomics substudy

Looking beyond GWAS: allele-specific transcription factor binding drives the association of GALNT2 to HDL-C plasma levels

Cavalli, Marco; Pan, Gang; Nord, Helena; Wadelius, Claes

Ingår i Lipids in Health and Disease, 2016.

DOI för Looking beyond GWAS: allele-specific transcription factor binding drives the association of GALNT2 to HDL-C plasma levels Ladda ner fulltext (pdf) av Looking beyond GWAS: allele-specific transcription factor binding drives the association of GALNT2 to HDL-C plasma levels

Maps of context-dependent putative regulatory regions and genomic signal interactions

Diamanti, Klev; Umer, Husen M.; Kruczyk, Marcin; Dabrowski, Michal J. et al.

Ingår i Nucleic Acids Research, s. 9110-9120, 2016.

DOI för Maps of context-dependent putative regulatory regions and genomic signal interactions Ladda ner fulltext (pdf) av Maps of context-dependent putative regulatory regions and genomic signal interactions

Novel regulatory variant detected on the VKORC1 haplotype that is associated with warfarin dose

Cavalli, Marco; Pan, Gang; Nord, Helena; Eriksson, Niclas et al.

Ingår i Pharmacogenomics (London), s. 1305-1314, 2016.

DOI för Novel regulatory variant detected on the VKORC1 haplotype that is associated with warfarin dose Ladda ner fulltext (pdf) av Novel regulatory variant detected on the VKORC1 haplotype that is associated with warfarin dose

Different distribution of histone modifications in genes with unidirectional and bidirectional transcription and a role of CTCF and cohesin in directing transcription

Bornelöv, Susanne; Komorowski, Jan; Wadelius, Claes

Ingår i BMC Genomics, 2015.

DOI för Different distribution of histone modifications in genes with unidirectional and bidirectional transcription and a role of CTCF and cohesin in directing transcription Ladda ner fulltext (pdf) av Different distribution of histone modifications in genes with unidirectional and bidirectional transcription and a role of CTCF and cohesin in directing transcription

lobChIP: from cells to sequencing ready ChIP libraries in a single day

Wallerman, Ola; Nord, Helena; Bysani, Madhusudhan; Borghini, Lisa et al.

Ingår i Epigenetics & Chromatin, 2015.

DOI för lobChIP: from cells to sequencing ready ChIP libraries in a single day Ladda ner fulltext (pdf) av lobChIP: from cells to sequencing ready ChIP libraries in a single day

Best vitelliform macular dystrophy in a Swedish family: genetic analysis and a seven-year follow-up of photodynamic treatment of a young boy with choroidal neovascularization

Frennesson, Christina I.; Wadelius, Claes; Nilsson, Sven Erik G.

Ingår i Acta Ophthalmologica, s. 238-242, 2014.

DOI för Best vitelliform macular dystrophy in a Swedish family: genetic analysis and a seven-year follow-up of photodynamic treatment of a young boy with choroidal neovascularization

Integration of genome-wide of Stat3 binding and epigenetic modification mapping with transcriptome reveals novel Stat3 target genes in glioma cells

Kruczyk, Marcin; Przanowski, Piotr; Dabrowski, Michal; Swiatek-Machado, Karolina et al.

Ingår i Biochimica et Biophysica Acta, s. 1341-1350, 2014.

DOI för Integration of genome-wide of Stat3 binding and epigenetic modification mapping with transcriptome reveals novel Stat3 target genes in glioma cells

Nucleosome regulatory dynamics in response to TGF beta

Enroth, Stefan; Andersson, Robin; Bysani, Madhusudhan; Wallerman, Ola et al.

Ingår i Nucleic Acids Research, s. 6921-6934, 2014.

DOI för Nucleosome regulatory dynamics in response to TGF beta

Nucleosome regulatory dynamics in response to TGF-beta treatment in HepG2 cells

Enroth, Stefan; Andersson, Robin; Bysani, Madhusudhan Reddy; Wallerman, Ola et al.

Ingår i Nucleic Acids Research, s. 6921-6934, 2014.

DOI för Nucleosome regulatory dynamics in response to TGF-beta treatment in HepG2 cells

ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer

Bysani, Madhu Sudhan Reddy; Wallerman, Ola; Bornelöv, Susanne; Zatloukal, Kurt et al.

Ingår i BMC Medical Genomics, s. 50-, 2013.

DOI för ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer

Genetic Determinants of Dabigatran Plasma Levels and Their Relation to Bleeding

Paré, Guillaume; Eriksson, Niclas; Lehr, Thorsten; Connolly, Stuart et al.

Ingår i Circulation, s. 1404-, 2013.

DOI för Genetic Determinants of Dabigatran Plasma Levels and Their Relation to Bleeding

A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements

Enroth, Stefan; Andersson, Claes R.; Andersson, Robin; Wadelius, Claes et al.

Ingår i Algorithms for Molecular Biology, s. 2-, 2012.

DOI för A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements Ladda ner fulltext (pdf) av A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements

Combinations of histone modifications mark exon inclusion levels

Enroth, Stefan; Bornelöv, Susanne; Wadelius, Claes; Komorowski, Jan

Ingår i PLOS ONE, 2012.

DOI för Combinations of histone modifications mark exon inclusion levels Ladda ner fulltext (pdf) av Combinations of histone modifications mark exon inclusion levels

Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa

Enroth, Stefan; Rada-Iglesisas, Alvaro; Andersson, Robin; Wallerman, Ola et al.

Ingår i BMC Cancer, s. 450-, 2011.

DOI för Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa Ladda ner fulltext (pdf) av Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

Thorleifsson, Gudmar; Walters, G. Bragi; Hewitt, Alex W.; Masson, Gisli et al.

Ingår i Nature Genetics, s. 906-909, 2010.

DOI för Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

Integrative epigenomic and genomic analysis of malignant pheochromocytoma.

Sandgren, Johanna; Andersson, A; Rada-Iglesias, A; Enroth, S et al.

Ingår i Experimental and Molecular Medicine, s. 484-502, 2010.

Integrative epigenomic and genomic analysis of malignant pheochromocytoma

Sandgren, Johanna; Andersson, Robin; Rada-Iglesias, Alvaro; Enroth, Stefan et al.

Ingår i Experimental and Molecular Medicine, s. 484-502, 2010.

DOI för Integrative epigenomic and genomic analysis of malignant pheochromocytoma

SICTIN: Rapid footprinting of massively parallel sequencing data

Enroth, Stefan; Andersson, Robin; Wadelius, Claes; Komorowski, Jan

Ingår i BioData Mining, 2010.

DOI för SICTIN: Rapid footprinting of massively parallel sequencing data Ladda ner fulltext (pdf) av SICTIN: Rapid footprinting of massively parallel sequencing data

Two polypyrimidine tracts in the nitric oxide synthase 2 gene: similar regulatory sequences with different properties

Motallebipour, Mehdi; Rada-Iglesias, Alvaro; Westin, Gunnar; Wadelius, Claes

Ingår i Molecular Biology Reports, s. 2021-2030, 2010.

DOI för Two polypyrimidine tracts in the nitric oxide synthase 2 gene: similar regulatory sequences with different properties

Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq

Motallebipour, Mehdi; Ameur, Adam; Bysani, Madhusudhan Reddy; Patra, Kalicharan et al.

Ingår i Genome Biology, s. R129-, 2009.

DOI för Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq

Histone H3 lysine 27 trimethylation in adult differentiated colon associated to cancer DNA hypermethylation

Rada-Iglesias, Alvaro; Enroth, Stefan; Andersson, Robin; Wanders, Alkwin et al.

Ingår i Epigenetics, s. 107-113, 2009.

Identification of candidate regulatory SNPs by combination of transcription-factor-binding site prediction, SNP genotyping and haploChIP

Ameur, Adam; Rada-Iglesias, Alvaro; Komorowski, Jan; Wadelius, Claes

Ingår i Nucleic Acids Research, s. e85-, 2009.

DOI för Identification of candidate regulatory SNPs by combination of transcription-factor-binding site prediction, SNP genotyping and haploChIP

Integrating genome and epigenome in human disease

Wadelius, Claes

Ingår i Epigenomics, s. 343-368, 2009.

DOI för Integrating genome and epigenome in human disease

Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing

Wallerman, Ola; Motallebipour, Mehdi; Enroth, Stefan; Patra, Kalicharan et al.

Ingår i Nucleic Acids Research, s. 7498-7508, 2009.

DOI för Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing

Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing

Wallerman, Ola; Motallebipour, Mehdi; Enroth, Stefan; Patra, Kalicharan et al.

Ingår i Nucleic Acids Research, s. 7498-7508, 2009.

DOI för Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing

Novel genes in cell cycle control and lipid metabolism with dynamically regulated binding sites for sterol regulatory element-binding protein 1 and RNA polymerase II in HepG2 cells detected by chromatin immunoprecipitation with microarray detection

Motallebipour, Mehdi; Enroth, Stefan; Punga, Tanel; Ameur, Adam et al.

Ingår i The FEBS Journal, s. 1878-1890, 2009.

DOI för Novel genes in cell cycle control and lipid metabolism with dynamically regulated binding sites for sterol regulatory element-binding protein 1 and RNA polymerase II in HepG2 cells detected by chromatin immunoprecipitation with microarray detection

Nucleosomes are well positioned in exons and carry characteristic histone modifications

Andersson, Robin; Enroth, Stefan; Rada-Iglesias, Alvaro; Wadelius, Claes et al.

Ingår i Genome Research, s. 1732-1741, 2009.

DOI för Nucleosomes are well positioned in exons and carry characteristic histone modifications

Two polypyrimidine tracts in the nitric oxide synthase 2 gene: similar regulatory sequences with different properties.

Motallebipour, M; Rada-Iglesias, A; Westin, Gunnar; Wadelius, Claes

Ingår i Molecular Biology Reports, s. 2021-2030, 2009.

ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth

Markljung, Ellen; Jiang, Lin; Jaffe, Jacob D.; Mikkelsen, Tarjei S. et al.

Ingår i PLoS biology, s. e1000256-, 2009.

DOI för ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth

Influence of adenosine triphosphate and ABCB1 (MDR1) genotype on the P-glycoprotein-dependent transfer of saquinavir in the dually perfused human placenta

Rahi, M.; Heikkinen, T.; Hakkola, J.; Hakala, K. et al.

Ingår i Human and Experimental Toxicology, s. 65-71, 2008.

DOI för Influence of adenosine triphosphate and ABCB1 (MDR1) genotype on the P-glycoprotein-dependent transfer of saquinavir in the dually perfused human placenta

Monte Carlo feature selection for supervised classification

Draminski, Michal; Rada-Iglesias, Alvaro; Enroth, Stefan; Wadelius, Claes et al.

Ingår i Bioinformatics, s. 110-117, 2008.

DOI för Monte Carlo feature selection for supervised classification

ORegAnno: an open-access community-driven resource for regulatory annotation

Griffith, Obi L.; Montgomery, Stephen B.; Bernier, Bridget; Chu, Bryan et al.

Ingår i Nucleic Acids Research, s. D107-D113, 2008.

DOI för ORegAnno: an open-access community-driven resource for regulatory annotation

Whole-genome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders

Rada-Iglesias, Alvaro; Ameur, Adam; Kapranov, Philipp; Enroth, Stefan et al.

Ingår i Genome Research, s. 380-392, 2008.

DOI för Whole-genome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders

Association of warfarin dose with genes involved in its action and metabolism

Wadelius, Mia; Chen, Leslie Y.; Eriksson, Niclas; Bumpstead, Suzannah et al.

Ingår i Human Genetics, s. 23-34, 2007.

DOI för Association of warfarin dose with genes involved in its action and metabolism

Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes

Rada-Iglesias, Alvaro; Enroth, Stefan; Ameur, Adam; Koch, Christoph M. et al.

Ingår i Genome Research, s. 708-719, 2007.

DOI för Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes

Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma

Thorleifsson, Gudmar; Magnusson, Kristinn P.; Sulem, Patrick; Walters, G. Bragi et al.

Ingår i Science, s. 1397-1400, 2007.

DOI för Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma

Enhanced accumulation of A2E in individuals homozygous or heterozygous for mutations in BEST1 (VMD2)

Bakall, Benjamin; Radu, R.A.; Stanton, J. B.; Burke, J. M. et al.

Ingår i Experimental Eye Research, s. 34-43, 2007.

DOI för Enhanced accumulation of A2E in individuals homozygous or heterozygous for mutations in BEST1 (VMD2)

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Birney, Ewan; Stamatoyannopoulos, John A.; Dutta, Anindya; Guigó, Roderic et al.

Ingår i Nature, s. 799-816, 2007.

DOI för Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

In vitro analysis of DNA-protein interactions by proximity ligation

Gustafsdottir, Sigrun M.; Schlingemann, Jörg; Rada-Iglesias, Alvaro; Schallmeiner, Edith et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 3067-3072, 2007.

DOI för In vitro analysis of DNA-protein interactions by proximity ligation

Placental transfer of quetiapine in relation to P-glycoprotein activity

Rahi, Melissa; Heikkinen, Tuija; Härtter, Sebastian; Hakkola, Jukka et al.

Ingår i Journal of Psychopharmacology, s. 751-756, 2007.

DOI för Placental transfer of quetiapine in relation to P-glycoprotein activity

Expression of bestrophin-1, the product of the VMD2 gene, modulates voltage-dependent Ca2+ channels in retinal pigment epithelial cells

Rosenthal, Rita; Bakall, Benjamin; Kinnick, Tyson; Peachy, Neal et al.

Ingår i The FASEB Journal, s. 178-80, 2006.

DOI för Expression of bestrophin-1, the product of the VMD2 gene, modulates voltage-dependent Ca2+ channels in retinal pigment epithelial cells

Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays

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Ingår i Human Molecular Genetics, s. 3435-3447, 2005.

DOI för Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays

Common VKORC1 and GGCX polymorphisms associated with warfarin dose

Wadelius, Mia; Chen, L.Y.; Downes, K.; Ghori, J. et al.

Ingår i The Pharmacogenomics Journal, s. 262-70, 2005.

DOI för Common VKORC1 and GGCX polymorphisms associated with warfarin dose

Functional role of P-glycoprotein in the human blood-placental barrier

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Ingår i Clinical Pharmacology and Therapeutics, s. 123-31, 2005.

DOI för Functional role of P-glycoprotein in the human blood-placental barrier

Warfarin sensitivity related to CYP2C9, CYP3A5, ABCB1 (MDR1) and other factors

Wadelius, Mia; Sörlin, Kristina; Wallerman, Ola; Karlsson, Jacob et al.

Ingår i The Pharmacogenomics Journal, s. 40-8, 2004.

DOI för Warfarin sensitivity related to CYP2C9, CYP3A5, ABCB1 (MDR1) and other factors

Polymorphisms in NAT2, CYP2D6, CYP2C19 and GSTP1 and their association with prostate cancer

Wadelius, Mia; Autrup, J.L.; Stubbins, M.J.; Andersson, S.O. et al.

Ingår i Pharmacogenetics, s. 333-40, 1999.

Prostate cancer associated with CYP17 genotype

Wadelius, Mia; Andersson, S.O.; Johansson, J.E.; Wadelius, Claes et al.

Ingår i Pharmacogenetics, s. 635-9, 1999.

Lamotrigine and toxic epidermal necrolysis

Wadelius, Mia; Karlsson, Torbjörn; Wadelius, Claes; Rane, Anders

Ingår i The Lancet, s. 1041-, 1996.

DOI för Lamotrigine and toxic epidermal necrolysis

Molecular analysis of chromosome 21 in a patient with a phenotype of down syndrome and apparently normal karyotype

Edman Ahlbom, Bodil; Goetz, P; Korenberg, JR; Pettersson, Ulf et al.

Ingår i American Journal of Medical Genetics. Part A, s. 566-572, 1996.

DOI för Molecular analysis of chromosome 21 in a patient with a phenotype of down syndrome and apparently normal karyotype

Single Nuclei Transcriptome Analysis of Human Liver with Integration of Proteomics and Capture Hi-C Bulk Tissue Data

Cavalli, Marco; Diamanti, Klev; Pan, Gang; Rapolas, Spalinskas et al.