Publikationer i DiVA – Bo Nilsson

How COVID-19 and other pathological conditions and medical treatments activate our intravascular innate immune system

Nilsson, Bo; Eriksson, Oskar; Fromell, Karin; Persson, Barbro et al.

Ingår i Frontiers in Immunology, 2023.

DOI för How COVID-19 and other pathological conditions and medical treatments activate our intravascular innate immune system Ladda ner fulltext (pdf) av How COVID-19 and other pathological conditions and medical treatments activate our intravascular innate immune system

A Robust Method to Store Complement C3 With Superior Ability to Maintain the Native Structure and Function of the Protein

Adler, Anna; Manivel, Vivek Anand; Fromell, Karin; Teramura, Yuji et al.

Ingår i Frontiers in Immunology, 2022.

DOI för A Robust Method to Store Complement C3 With Superior Ability to Maintain the Native Structure and Function of the Protein Ladda ner fulltext (pdf) av A Robust Method to Store Complement C3 With Superior Ability to Maintain the Native Structure and Function of the Protein

Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation: A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients

Hultström, Michael; Fromell, Karin; Larsson, Anders; Persson, Barbro et al.

Ingår i Biomedicines, 2022.

DOI för Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation: A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients Ladda ner fulltext (pdf) av Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation: A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients

Blood compatibility of widely used central venous catheters; an experimental study

Thorarinsdottir, Hulda; Kander, Thomas; Johansson, Dorota; Nilsson, Bo et al.

Ingår i Scientific Reports, 2022.

DOI för Blood compatibility of widely used central venous catheters; an experimental study Ladda ner fulltext (pdf) av Blood compatibility of widely used central venous catheters; an experimental study

Complement C3 activation in the ICU: Disease and therapy as Bonnie and Clyde

Mannes, Marco; Mastellos, Dimitrios C.; Ekdahl, Kristina N.; Nilsson, Bo et al.

Ingår i Seminars in Immunology, 2022.

DOI för Complement C3 activation in the ICU: Disease and therapy as Bonnie and Clyde

Complement C3 inhibition in severe COVID-19 using compstatin AMY-101

Skendros, Panagiotis; Germanidis, Georgios; Mastellos, Dimitrios C.; Antoniadou, Christina et al.

Ingår i Science Advances, 2022.

DOI för Complement C3 inhibition in severe COVID-19 using compstatin AMY-101 Ladda ner fulltext (pdf) av Complement C3 inhibition in severe COVID-19 using compstatin AMY-101

Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases

Lundtoft, Christian; Pucholt, Pascal; Martin, Myriam; Bianchi, Matteo et al.

Ingår i Arthritis & Rheumatology, s. 1440-1450, 2022.

DOI för Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases Ladda ner fulltext (pdf) av Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases

Effect of liposome surface modification with water-soluble phospholipid polymer chain-conjugated lipids on interaction with human plasma proteins

Adler, Anna; Inoue, Yuuki; Nilsson Ekdahl, Kristina; Baba, Teruhiko et al.

Ingår i Journal of materials chemistry. B, s. 2512-2522, 2022.

DOI för Effect of liposome surface modification with water-soluble phospholipid polymer chain-conjugated lipids on interaction with human plasma proteins

Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19

Hultström, Michael; Frithiof, Robert; Grip, Jonathan; Lindelöf, Linnea et al.

Ingår i Nature Immunology, s. 861-864, 2022.

DOI för Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19

How the Innate Immune System of the Blood Contributes to Systemic Pathology in COVID-19-Induced ARDS and Provides Potential Targets for Treatment

Nilsson, Bo; Persson, Barbro; Eriksson, Oskar; Fromell, Karin et al.

Ingår i Frontiers in Immunology, 2022.

DOI för How the Innate Immune System of the Blood Contributes to Systemic Pathology in COVID-19-Induced ARDS and Provides Potential Targets for Treatment Ladda ner fulltext (pdf) av How the Innate Immune System of the Blood Contributes to Systemic Pathology in COVID-19-Induced ARDS and Provides Potential Targets for Treatment

Impact of spontaneous liposome modification with phospholipid polymer-lipid conjugates on protein interactions

Suzuki, Haruna; Adler, Anna; Huang, Tianwei; Kuramochi, Akiko et al.

Ingår i Science and Technology of Advanced Materials, s. 845-857, 2022.

DOI för Impact of spontaneous liposome modification with phospholipid polymer-lipid conjugates on protein interactions Ladda ner fulltext (pdf) av Impact of spontaneous liposome modification with phospholipid polymer-lipid conjugates on protein interactions

Impaired Antibody Response Is Associated with Histone-Release, Organ Dysfunction and Mortality in Critically Ill COVID-19 Patients.

Lagedal, Rickard; Eriksson, Oskar; Sörman, Anna; Huckriede, Joram B et al.

Ingår i Journal of clinical medicine, 2022.

DOI för Impaired Antibody Response Is Associated with Histone-Release, Organ Dysfunction and Mortality in Critically Ill COVID-19 Patients. Ladda ner fulltext (pdf) av Impaired Antibody Response Is Associated with Histone-Release, Organ Dysfunction and Mortality in Critically Ill COVID-19 Patients.

Modulation of Neutrophil Activity by Soluble Complement Cleavage Products-An In-Depth Analysis

Wohlgemuth, Lisa; Stratmann, Alexander Elias Paul; Muennich, Frederik; Bernhard, Stefan et al.

Ingår i Cells, 2022.

DOI för Modulation of Neutrophil Activity by Soluble Complement Cleavage Products-An In-Depth Analysis Ladda ner fulltext (pdf) av Modulation of Neutrophil Activity by Soluble Complement Cleavage Products-An In-Depth Analysis

Variation of Complement Protein Levels in Maternal Plasma and Umbilical Cord Blood during Normal Pregnancy: An Observational Study

Saleh, Muna; Compagno, Michele; Pihl, Sofia; Strevens, Helena et al.

Ingår i Journal of Clinical Medicine, 2022.

DOI för Variation of Complement Protein Levels in Maternal Plasma and Umbilical Cord Blood during Normal Pregnancy: An Observational Study Ladda ner fulltext (pdf) av Variation of Complement Protein Levels in Maternal Plasma and Umbilical Cord Blood during Normal Pregnancy: An Observational Study

Cell Surface Functionalization with Heparin-Conjugated Lipid to Suppress Blood Activation

Asawa, Kenta; Ishihara, Kazuhiko; Nilsson Ekdahl, Kristina; Nilsson, Bo et al.

Ingår i Advanced Functional Materials, 2021.

DOI för Cell Surface Functionalization with Heparin-Conjugated Lipid to Suppress Blood Activation

Complement as driver of systemic inflammation and organ failure in trauma, burn, and sepsis

Mannes, Marco; Schmidt, Christoph Q.; Nilsson, Bo; Nilsson Ekdahl, Kristina et al.

Ingår i Seminars in Immunopathology, s. 773-788, 2021.

DOI för Complement as driver of systemic inflammation and organ failure in trauma, burn, and sepsis Ladda ner fulltext (pdf) av Complement as driver of systemic inflammation and organ failure in trauma, burn, and sepsis

Harnessing hyaluronic acid-based nanoparticles for combination therapy: A novel approach for suppressing systemic inflammation and to promote antitumor macrophage polarization

Rangasami, Vignesh K.; Samanta, Sumanta; Parihar, Vijay Singh; Asawa, Kenta et al.

Ingår i Carbohydrate Polymers, 2021.

DOI för Harnessing hyaluronic acid-based nanoparticles for combination therapy: A novel approach for suppressing systemic inflammation and to promote antitumor macrophage polarization

Hemocompatibility of Nanotitania-Nanocellulose Hybrid Materials

Svensson, Fredric G.; Manivel, Vivek Anand; Seisenbaeva, Gulaim A.; Kessler, Vadim G. et al.

Ingår i Nanomaterials, 2021.

DOI för Hemocompatibility of Nanotitania-Nanocellulose Hybrid Materials Ladda ner fulltext (pdf) av Hemocompatibility of Nanotitania-Nanocellulose Hybrid Materials

Immunopathophysiology of trauma-related acute kidney injury

Messerer, David A. C.; Halbgebauer, Rebecca; Nilsson, Bo; Pavenstaedt, Hermann et al.

Ingår i Nature Reviews Nephrology, s. 91-111, 2021.

DOI för Immunopathophysiology of trauma-related acute kidney injury

Induction of Spontaneous Liposome Adsorption by Exogenous Surface Modification with Cell-Penetrating Peptide-Conjugated Lipids

Sato, Yuya; Asawa, Kenta; Huang, Tianwei; Noiri, Makoto et al.

Ingår i Langmuir, s. 9711-9723, 2021.

DOI för Induction of Spontaneous Liposome Adsorption by Exogenous Surface Modification with Cell-Penetrating Peptide-Conjugated Lipids

Interdialytic weight gain of less than 2.5% seems to limit cardiac damage during hemodialysis

Goto, Junko; Forsberg, Ulf; Jonsson, Per; Matsuda, Kenichi et al.

Ingår i International Journal of Artificial Organs, s. 539-550, 2021.

DOI för Interdialytic weight gain of less than 2.5% seems to limit cardiac damage during hemodialysis Ladda ner fulltext (pdf) av Interdialytic weight gain of less than 2.5% seems to limit cardiac damage during hemodialysis

Interleukin 8 Elicits Rapid Physiological Changes in Neutrophils That Are Altered by Inflammatory Conditions

Bernhard, Stefan; Hug, Stefan; Stratmann, Alexander Elias Paul; Erber, Maike et al.

Ingår i Journal of Innate Immunity, s. 225-241, 2021.

DOI för Interleukin 8 Elicits Rapid Physiological Changes in Neutrophils That Are Altered by Inflammatory Conditions Ladda ner fulltext (pdf) av Interleukin 8 Elicits Rapid Physiological Changes in Neutrophils That Are Altered by Inflammatory Conditions

Pluronic Micelle-Mediated Tissue Factor Silencing Enhances Hemocompatibility, Stemness, Differentiation Potential, and Paracrine Signaling of Mesenchymal Stem Cells

Rangasami, Vignesh K.; Nawale, Ganesh N.; Asawa, Kenta; Kadekar, Sandeep et al.

Ingår i Biomacromolecules, s. 1980-1989, 2021.

DOI för Pluronic Micelle-Mediated Tissue Factor Silencing Enhances Hemocompatibility, Stemness, Differentiation Potential, and Paracrine Signaling of Mesenchymal Stem Cells Ladda ner fulltext (pdf) av Pluronic Micelle-Mediated Tissue Factor Silencing Enhances Hemocompatibility, Stemness, Differentiation Potential, and Paracrine Signaling of Mesenchymal Stem Cells

Synthesis of poly(2-methacryloyloxyethyl phosphorylcholine)-conjugated lipids and their characterization and surface properties of modified liposomes for protein interactions

Adler, Anna; Inoue, Yuuki; Sato, Yuya; Ishihara, Kazuhiko et al.

Ingår i Biomaterials Science, s. 5854-5867, 2021.

DOI för Synthesis of poly(2-methacryloyloxyethyl phosphorylcholine)-conjugated lipids and their characterization and surface properties of modified liposomes for protein interactions

The Complex Relationship between C4b-Binding Protein, Warfarin, and Antiphospholipid Antibodies

Grosso, Giorgia; Sandholm, Kerstin; Antovic, Aleksandra; Gunnarsson, Iva et al.

Ingår i Thrombosis and Haemostasis, s. 1299-1309, 2021.

DOI för The Complex Relationship between C4b-Binding Protein, Warfarin, and Antiphospholipid Antibodies

The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System

Lipcsey, Miklós; Persson, Barbro; Eriksson, Oskar; Blom, Anna M. et al.

Ingår i Frontiers in Immunology, 2021.

DOI för The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System Ladda ner fulltext (pdf) av The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System

Transcriptome analysis of post-mortem brain tissue reveals up-regulation of the complement cascade in a subgroup of schizophrenia patients

Lindholm Carlström, Eva; Niazi, Adnan; Etemadikhah, Mitra; Halvardson, Jonatan et al.

Ingår i Genes, 2021.

DOI för Transcriptome analysis of post-mortem brain tissue reveals up-regulation of the complement cascade in a subgroup of schizophrenia patients Ladda ner fulltext (pdf) av Transcriptome analysis of post-mortem brain tissue reveals up-regulation of the complement cascade in a subgroup of schizophrenia patients

Animal-Free Human Whole Blood Sepsis Model to Study Changes in Innate Immunity

Messerer, David Alexander Christian; Vidoni, Laura; Erber, Maike; Stratmann, Alexander Elias Paul et al.

Ingår i Frontiers in Immunology, 2020.

DOI för Animal-Free Human Whole Blood Sepsis Model to Study Changes in Innate Immunity Ladda ner fulltext (pdf) av Animal-Free Human Whole Blood Sepsis Model to Study Changes in Innate Immunity

Assessment of the Role of C3(H2O) in the Alternative Pathway

Fromell, Karin; Adler, Anna; Åman, Amanda; Manivel, Vivek Anand et al.

Ingår i Frontiers in Immunology, 2020.

DOI för Assessment of the Role of C3(H2O) in the Alternative Pathway Ladda ner fulltext (pdf) av Assessment of the Role of C3(H2O) in the Alternative Pathway

Blood type A associates with critical COVID-19 and death in a Swedish cohort

Hultström, Michael; Persson, Barbro; Eriksson, Oskar; Lipcsey, Miklós et al.

Ingår i Critical Care, 2020.

DOI för Blood type A associates with critical COVID-19 and death in a Swedish cohort Ladda ner fulltext (pdf) av Blood type A associates with critical COVID-19 and death in a Swedish cohort

Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy

Mastellos, Dimitrios C.; Pires da Silva, Bruno G. P.; Fonseca, Benedito A. L.; Fonseca, Natasha P. et al.

Ingår i Clinical Immunology, 2020.

DOI för Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy

Complement deposition, C4d, on platelets is associated with vascular events in systemic lupus erythematosus

Svenungsson, Elisabet; Gustafsson, Johanna T.; Grosso, Giorgia; Rossides, Marios et al.

Ingår i Rheumatology, s. 3264-3274, 2020.

DOI för Complement deposition, C4d, on platelets is associated with vascular events in systemic lupus erythematosus Ladda ner fulltext (pdf) av Complement deposition, C4d, on platelets is associated with vascular events in systemic lupus erythematosus

Discrepancies in plasma levels of complement components measured by a newly introduced commercially available magnetic bead technique compared to presently available clinical reference intervals

Sandholm, Kerstin; Carlsson, Hanna; Persson, Barbro; Skattum, Lillemor et al.

Ingår i Scandinavian Journal of Immunology, 2020.

DOI för Discrepancies in plasma levels of complement components measured by a newly introduced commercially available magnetic bead technique compared to presently available clinical reference intervals

Identification of Metal-Binding Peptides and Their Conjugation onto Nanoparticles of Superparamagnetic Iron Oxides and Liposomes

Kodama, Tomonobu; Yoshihara, Akifumi; Goel, Isha; Sekino, Masaki et al.

Ingår i ACS Applied Materials and Interfaces, s. 24623-24634, 2020.

DOI för Identification of Metal-Binding Peptides and Their Conjugation onto Nanoparticles of Superparamagnetic Iron Oxides and Liposomes

Mannose-Binding Lectin is Associated with Thrombosis and Coagulopathy in Critically Ill COVID-19 Patients

Eriksson, Oskar; Hultström, Michael; Persson, Barbro; Lipcsey, Miklós et al.

Ingår i Thrombosis and haemostasis, s. 1720-1724, 2020.

DOI för Mannose-Binding Lectin is Associated with Thrombosis and Coagulopathy in Critically Ill COVID-19 Patients

Poly(2-aminoethyl methacrylate)-based polyampholyte brush surface with carboxylic groups to improve blood compatibility

Azuma, Tomoyuki; Matsushita, Taishi; Manivel, Vivek Anand; Nilsson Ekdahl, Kristina et al.

Ingår i Journal of Biomaterials Science. Polymer Edition, s. 679-693, 2020.

DOI för Poly(2-aminoethyl methacrylate)-based polyampholyte brush surface with carboxylic groups to improve blood compatibility

Potential of Cell Surface Engineering with Biocompatible Polymers for Biomedical Applications

Teramura, Yuji; Nilsson Ekdahl, Kristina; Fromell, Karin; Nilsson, Bo et al.

Ingår i Langmuir, s. 12088-12106, 2020.

DOI för Potential of Cell Surface Engineering with Biocompatible Polymers for Biomedical Applications

Promotion of cell membrane fusion by cell-cell attachment through cell surface modification with functional peptide-PEG-lipids

Yoshihara, Akifumi; Watanabe, Sayumi; Goel, Isha; Ishihara, Kazuhiko et al.

Ingår i Biomaterials, 2020.

DOI för Promotion of cell membrane fusion by cell-cell attachment through cell surface modification with functional peptide-PEG-lipids

Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock

Halbgebauer, Rebecca; Karasu, Ebru; Braun, Christian K.; Palmer, Annette et al.

Ingår i Frontiers in Immunology, 2020.

DOI för Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock Ladda ner fulltext (pdf) av Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock

A case of systemic lupus erythematosus with C1q deficiency, increased serum interferon-a levels and high serum interferogenic activity

Bolin, Karin; Eloranta, Maija-Leena; Kozyrev, Sergey V.; Dahlqvist, Johanna et al.

Ingår i Rheumatology, s. 918-919, 2019.

DOI för A case of systemic lupus erythematosus with C1q deficiency, increased serum interferon-a levels and high serum interferogenic activity

A human whole-blood model to study the activation of innate immunity system triggered by nanoparticles as a demonstrator for toxicity

N.Ekdahl, Kristina; Fromell, Karin; Mohlin, Camilla; Teramura, Yuji et al.

Ingår i Science and Technology of Advanced Materials, s. 688-698, 2019.

DOI för A human whole-blood model to study the activation of innate immunity system triggered by nanoparticles as a demonstrator for toxicity Ladda ner fulltext (pdf) av A human whole-blood model to study the activation of innate immunity system triggered by nanoparticles as a demonstrator for toxicity

C3-Glomerulopathy Autoantibodies Mediate Distinct Effects on Complement C3-and C5-Convertases

Zhao, Fei; Afonso, Sara; Lindner, Susanne; Hartmann, Andrea et al.

Ingår i Frontiers in Immunology, 2019.

DOI för C3-Glomerulopathy Autoantibodies Mediate Distinct Effects on Complement C3-and C5-Convertases Ladda ner fulltext (pdf) av C3-Glomerulopathy Autoantibodies Mediate Distinct Effects on Complement C3-and C5-Convertases

Current and Future Approaches for Monitoring Responses to Anti-complement Therapeutics

Mohebnasab, Maedeh; Eriksson, Oskar; Persson, Barbro; Sandholm, Kerstin et al.

Ingår i Frontiers in Immunology, 2019.

DOI för Current and Future Approaches for Monitoring Responses to Anti-complement Therapeutics Ladda ner fulltext (pdf) av Current and Future Approaches for Monitoring Responses to Anti-complement Therapeutics

Evaluation of a Novel Immunoassay for Quantification of C1q for Clinical Diagnostic Use

Sandholm, Kerstin; Persson, Barbro; Skattum, Lillemor; Eggertsen, Gosta et al.

Ingår i Frontiers in Immunology, 2019.

DOI för Evaluation of a Novel Immunoassay for Quantification of C1q for Clinical Diagnostic Use Ladda ner fulltext (pdf) av Evaluation of a Novel Immunoassay for Quantification of C1q for Clinical Diagnostic Use

Exposure of von Willebrand Factor on Isolated Hepatocytes Promotes Tethering of Platelets to the Cell Surface

Gustafson, Elisabet K.; Hamad, Osama A.; Deckmyn, Hans; Barbu, Andreea R et al.

Ingår i Transplantation, s. 1630-1638, 2019.

DOI för Exposure of von Willebrand Factor on Isolated Hepatocytes Promotes Tethering of Platelets to the Cell Surface

Is generation of C3(H₂O) necessary for activation of the alternative pathway in real life?

Nilsson Ekdahl, Kristina; Mohlin, Camilla; Adler, Anna; Åman, Amanda et al.

Ingår i Molecular Immunology, s. 353-361, 2019.

DOI för Is generation of C3(H₂O) necessary for activation of the alternative pathway in real life? Ladda ner fulltext (pdf) av Is generation of C3(H₂O) necessary for activation of the alternative pathway in real life?

Modification of human MSC surface with oligopeptide-PEG-lipids for selective binding to activated endothelium

Noiri, Makoto; Asawa, Kenta; Okada, Naoya; Kodama, Tomonobu et al.

Ingår i Journal of Biomedical Materials Research. Part A, s. 1779-1792, 2019.

DOI för Modification of human MSC surface with oligopeptide-PEG-lipids for selective binding to activated endothelium

Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation

von Zur-Mühlen, Bengt; Lundgren, Torbjorn; Bayman, Levent; Berne, Christian et al.

Ingår i Transplantation, s. 630-637, 2019.

DOI för Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation Ladda ner fulltext (pdf) av Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation

Optimization of Islet Microencapsulation with Thin Polymer Membranes for Long-Term Stability

Toda, Shota; Fattah, Artin; Asawa, Kenta; Nakamura, Naoko et al.

Ingår i Micromachines, 2019.

DOI för Optimization of Islet Microencapsulation with Thin Polymer Membranes for Long-Term Stability Ladda ner fulltext (pdf) av Optimization of Islet Microencapsulation with Thin Polymer Membranes for Long-Term Stability

Polyvinylalcohol-carbazate (PVAC) reduces red blood cell hemolysis

Sellberg, Felix; Fredriksson, Fanny; Engstrand, Thomas; Bowden, Tim et al.

Ingår i PLOS ONE, 2019.

DOI för Polyvinylalcohol-carbazate (PVAC) reduces red blood cell hemolysis Ladda ner fulltext (pdf) av Polyvinylalcohol-carbazate (PVAC) reduces red blood cell hemolysis

PROTECTIVE EFFECTS OF THE COMPLEMENT INHIBITOR COMPSTATIN CP40 IN HEMORRHAGIC SHOCK

van Griensven, Martijn; Ricklin, Daniel; Denk, Stephanie; Halbgebauer, Rebecca et al.

Ingår i Shock, s. 78-87, 2019.

DOI för PROTECTIVE EFFECTS OF THE COMPLEMENT INHIBITOR COMPSTATIN CP40 IN HEMORRHAGIC SHOCK

'Stealth' corporate innovation: an emerging threat for therapeutic drug development

Mastellos, Dimitrios C.; Blom, Anna M.; Connolly, E. Sander; Daha, Mohamed R. et al.

Ingår i Nature Immunology, s. 1409-1413, 2019.

DOI för 'Stealth' corporate innovation: an emerging threat for therapeutic drug development

Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction

Karasu, Ebru; Nilsson, Bo; Köhl, Jörg; Lambris, John D. et al.

Ingår i Frontiers in Immunology, 2019.

DOI för Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction Ladda ner fulltext (pdf) av Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction

The Human Platelet as an Innate Immune Cell: Interactions Between Activated Platelets and the Complement System

Eriksson, Oskar; Mohlin, Camilla; Nilsson, Bo; N. Ekdahl, Kristina

Ingår i Frontiers in Immunology, 2019.

DOI för The Human Platelet as an Innate Immune Cell: Interactions Between Activated Platelets and the Complement System Ladda ner fulltext (pdf) av The Human Platelet as an Innate Immune Cell: Interactions Between Activated Platelets and the Complement System

Two subgroups in systemic lupus erythematosus with features of antiphospholipid or Sjogren's syndrome differ in molecular signatures and treatment perspectives

Idborg, Helena; Zandian, Arash; Sandberg, Ann-Sofi; Nilsson, Bo et al.

Ingår i Arthritis Research & Therapy, 2019.

DOI för Two subgroups in systemic lupus erythematosus with features of antiphospholipid or Sjogren's syndrome differ in molecular signatures and treatment perspectives Ladda ner fulltext (pdf) av Two subgroups in systemic lupus erythematosus with features of antiphospholipid or Sjogren's syndrome differ in molecular signatures and treatment perspectives

Validation of an MPC polymer coating to attenuate surface- induced cross-talk between the complement and coagulation systems in whole blood in in vitro and in vivo models

Asif, Sana; Asawa, Kenta; Yuuki, Inoue; Ishihara, Kazuhiko et al.

Ingår i Macromolecular Bioscience, 2019.

DOI för Validation of an MPC polymer coating to attenuate surface- induced cross-talk between the complement and coagulation systems in whole blood in in vitro and in vivo models

Author Correction: Dispersion of TiO₂ nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins

Seisenbaeva, Gulaim A.; Fromell, Karin; Vinogradov, Vasiliy V.; Terekhov, Aleksey N. et al.

Ingår i Scientific Reports, 2018.

DOI för Author Correction: Dispersion of TiO₂ nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins Ladda ner fulltext (pdf) av Author Correction: Dispersion of TiO₂ nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins

Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions

Huber-Lang, Markus; Nilsson Ekdahl, Kristina; Wiegner, Rebecca; Fromell, Karin et al.

Ingår i Seminars in Immunopathology, s. 87-102, 2018.

DOI för Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions Ladda ner fulltext (pdf) av Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions

Contact (kallikrein/kinin) system activation in whole human blood induced by low concentrations of α-Fe2O3 nanoparticles.

Nilsson Ekdahl, Kristina; Davoodpour, Padideh; Ekstrand-Hammarström, Barbro; Fromell, Karin et al.

Ingår i Nanomedicine, s. 735-744, 2018.

DOI för Contact (kallikrein/kinin) system activation in whole human blood induced by low concentrations of α-Fe2O3 nanoparticles.

Generation of an alternative pathway convertase by contact-activated C3 is dependent on the conformation of C3

Fromell, Karin; Johansson, Ulrika; Dührkop, Claudia; Adler, Anna et al.

Ingår i Molecular Immunology, s. 193-193, 2018.

DOI för Generation of an alternative pathway convertase by contact-activated C3 is dependent on the conformation of C3

Interpretation of Serological Complement Biomarkers in Disease

Nilsson Ekdahl, Kristina; Persson, Barbro; Mohlin, Camilla; Sandholm, Kerstin et al.

Ingår i Frontiers in Immunology, 2018.

DOI för Interpretation of Serological Complement Biomarkers in Disease Ladda ner fulltext (pdf) av Interpretation of Serological Complement Biomarkers in Disease

Is the polarized secretion of complement factor H of importance in age-related macular degeneration?

Mohlin, Camilla; Petrus-Reurer, Sandra; Lanner, Fredrik; Sandholm, Kerstin et al.

Ingår i Investigative Ophthalmology and Visual Science, 2018.

PROTECTIVE EFFECTS OF THE COMPLEMENT INHIBITOR COMPSTATIN CP40 IN HEMORRHAGIC SHOCK

van Griensven, Martijn; Ricklin, Daniel; Denk, Stephanie; Halbgebauer, Rebecca et al.

Ingår i Shock, s. 117-118, 2018.

DOI för PROTECTIVE EFFECTS OF THE COMPLEMENT INHIBITOR COMPSTATIN CP40 IN HEMORRHAGIC SHOCK

Safety profile after prolonged C3 inhibition

Reis, Edimara S.; Berger, Nadja; Wang, Xin; Koutsogiannaki, Sophia et al.

Ingår i Clinical Immunology, s. 96-106, 2018.

DOI för Safety profile after prolonged C3 inhibition

Shiga toxin 2a binds antithrombin and heparin, but does not directly activate platelets

Knabl, Ludwig; Berktold, Michael; Hamad, Osama A.; Fromell, Karin et al.

Ingår i International Journal of Medical Microbiology, s. 969-976, 2018.

DOI för Shiga toxin 2a binds antithrombin and heparin, but does not directly activate platelets

The lectin pathway of complement and the contact/kallikrein system are integrated

Fromell, Karin; Dührkop, Claudia; Kozarcanin, Huda; Johansson, Ulrika et al.

Ingår i Molecular Immunology, s. 151-152, 2018.

DOI för The lectin pathway of complement and the contact/kallikrein system are integrated

The multifaceted role of complement in kidney transplantation

Biglarnia, Ali-Reza; Huber-Lang, Markus; Mohlin, Camilla; Nilsson Ekdahl, Kristina et al.

Ingår i Nature Reviews Nephrology, s. 767-781, 2018.

DOI för The multifaceted role of complement in kidney transplantation

The Optimization of the Hepatocyte Surface Modification Procedures in Terms of Heparin and Apyrase for Improving Hepatocyte Engraftment

Ogasawara, Hiroyuki; Teramura, Yuji; Imura, Takehiro; Inagaki, Akiko et al.

Ingår i Transplantation, s. S727-S727, 2018.

DOI för The Optimization of the Hepatocyte Surface Modification Procedures in Terms of Heparin and Apyrase for Improving Hepatocyte Engraftment

A protective role of complement regulators linked to a PEG phospholipid construct in reducing ischemic reperfusion injury in transplantation

Nilsson, Bo; Asif, Sana; Ekdahl N., Kristina; Manell, Elin et al.

Ingår i Molecular Immunology, s. 208-208, 2017.

DOI för A protective role of complement regulators linked to a PEG phospholipid construct in reducing ischemic reperfusion injury in transplantation

Absence of conformational change in complement factor 3 and factor XII adsorbed to acrylate polymers is related to a high degree of polymer backbone flexibility

Fromell, Karin; Yang, Yi; Nilsson Ekdahl, Kristina; Nilsson, Bo et al.

Ingår i Biointerphases, 2017.

DOI för Absence of conformational change in complement factor 3 and factor XII adsorbed to acrylate polymers is related to a high degree of polymer backbone flexibility Ladda ner fulltext (pdf) av Absence of conformational change in complement factor 3 and factor XII adsorbed to acrylate polymers is related to a high degree of polymer backbone flexibility

Cardiovascular disease in haemodialysis: role of the intravascular innate immune system.

Ekdahl, Kristina N; Soveri, Inga; Hilborn, Jöns; Fellström, Bengt et al.

Ingår i Nature Reviews Nephrology, s. 285-296, 2017.

DOI för Cardiovascular disease in haemodialysis: role of the intravascular innate immune system.

Cell Adhesion Induced Using Surface Modification with Cell-Penetrating Peptide-Conjugated Poly(ethylene glycol)-Lipid: A New Cell Glue for 3D Cell-Based Structures

Teramura, Yuji; Asif, Sana; Nilsson Ekdahl, Kristina; Gustafson, Elisabet K. et al.

Ingår i ACS Applied Materials and Interfaces, s. 244-254, 2017.

DOI för Cell Adhesion Induced Using Surface Modification with Cell-Penetrating Peptide-Conjugated Poly(ethylene glycol)-Lipid: A New Cell Glue for 3D Cell-Based Structures

Complement C5a Functions as a Master Switch for the pH Balance in Neutrophils Exerting Fundamental Immunometabolic Effects

Denk, Stephanie; Neher, Miriam D.; Messerer, David A. C.; Wiegner, Rebecca et al.

Ingår i Journal of Immunology, s. 4846-4854, 2017.

DOI för Complement C5a Functions as a Master Switch for the pH Balance in Neutrophils Exerting Fundamental Immunometabolic Effects

Complement system proteins in human embryonic stem cell-derived retinal pigment epithelial cells co-cultured with or without porcine retina

Mohlin, C.; Petrus-Reurer, S.; Lanner, F.; Sandholm, K. et al.

Ingår i Molecular Immunology, s. 162-163, 2017.

DOI för Complement system proteins in human embryonic stem cell-derived retinal pigment epithelial cells co-cultured with or without porcine retina

Control of IBMIR induced by fresh and cryopreserved hepatocytes by low molecular weight dextran sulfate

Gustafson, Elisabet; Asif, Sana; Kozarcanin, Huda; Meurling, Staffan et al.

Ingår i Cell Transplantation, s. 71-81, 2017.

DOI för Control of IBMIR induced by fresh and cryopreserved hepatocytes by low molecular weight dextran sulfate Ladda ner fulltext (pdf) av Control of IBMIR induced by fresh and cryopreserved hepatocytes by low molecular weight dextran sulfate

Dispersion of TiO₂ nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins

Seisenbaeva, Gulaim A.; Fromell, Karin; Vinogradov, Vasiliy V.; Terekhov, Aleksey N. et al.

Ingår i Scientific Reports, 2017.

DOI för Dispersion of TiO₂ nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins Ladda ner fulltext (pdf) av Dispersion of TiO₂ nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins

Forms of contact-activated C3 associated with AP convertase formation

Fromell, Karin; Dührkop, Claudia; Johansson, Ulrika; Nilsson Ekdahl, Kristina et al.

Ingår i Molecular Immunology, s. 141-141, 2017.

DOI för Forms of contact-activated C3 associated with AP convertase formation

Method development and validation for the quantitation of the complement inhibitor Cp40 in human and cynomolgus monkey plasma by UPLC-ESI-MS

Primikyri, Alexandra; Papanastasiou, Malvina; Sarigiannis, Yiannis; Koutsogiannaki, Sophia et al.

Ingår i Journal of chromatography. B, s. 19-26, 2017.

DOI för Method development and validation for the quantitation of the complement inhibitor Cp40 in human and cynomolgus monkey plasma by UPLC-ESI-MS

The innate immunity response: A key factor in biocompatibility

Ekdahl, Kristina N; Fromell, Karin; Hilborn, Jöns; Nilsson, Bo

Ingår i Bioresorbable Polymers for Biomedical Applications, s. 85-94, 2017.

The link between morphology and complement in ocular disease

Mohlin, Camilla; Sandholm, Kerstin; Nilsson Ekdahl, Kristina; Nilsson, Bo

Ingår i Molecular Immunology, s. 84-99, 2017.

DOI för The link between morphology and complement in ocular disease

Activation of Complement C3 Does NotHamper the Outcome of Experimental Intramuscular Islet Transplantation

Espes, Daniel; Pekna, Marcela; Nilsson, Bo; Carlsson, Per-Ola

Ingår i Transplantation, s. E6-E7, 2016.

DOI för Activation of Complement C3 Does NotHamper the Outcome of Experimental Intramuscular Islet Transplantation

Characterization of innate immunity in an extended whole blood model of human islet allotransplantation

Hårdstedt, Maria; Lindblom, Susanne; Karlsson-Para, Alex; Nilsson, Bo et al.

Ingår i Cell Transplantation, s. 503-515, 2016.

DOI för Characterization of innate immunity in an extended whole blood model of human islet allotransplantation

Chondroitin sulfate coated gold nanoparticles: a new strategy to resolve multidrug resistance and thromboinflammation

Gurav, Deepanjali; Varghese, Oommen P.; Hamad, Osama A.; Nilsson, Bo et al.

Ingår i Chemical Communications, s. 966-969, 2016.

DOI för Chondroitin sulfate coated gold nanoparticles: a new strategy to resolve multidrug resistance and thromboinflammation

Complement analysis 2016: Clinical indications, laboratory diagnostics and quality control

Prohaszka, Zoltan; Nilsson, Bo; Frazer-Abel, Ashley; Kirschfink, Michael

Ingår i Immunobiology, s. 1247-1258, 2016.

DOI för Complement analysis 2016: Clinical indications, laboratory diagnostics and quality control

Complement inhibition in biomaterial- and biosurface-induced thromboinflammation

Ekdahl, Kristina N.; Huang, Shan; Nilsson, Bo; Teramura, Yuji

Ingår i Seminars in Immunology, s. 268-277, 2016.

DOI för Complement inhibition in biomaterial- and biosurface-induced thromboinflammation

Complement Receptor 2 is increased in cerebrospinal fluid of multiple sclerosis patients and regulates C3 function

Lindblom, Rickard; Aeinehband, Shahin; Ström, Mikael; Al Nimer, Faiez et al.

Ingår i Clinical Immunology, s. 89-95, 2016.

DOI för Complement Receptor 2 is increased in cerebrospinal fluid of multiple sclerosis patients and regulates C3 function Ladda ner fulltext (pdf) av Complement Receptor 2 is increased in cerebrospinal fluid of multiple sclerosis patients and regulates C3 function

Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation

Nilsson Ekdahl, Kristina; Teramura, Yuji; Hamad, Osama A.; Asif, Sana et al.

Ingår i Immunological Reviews, s. 245-269, 2016.

DOI för Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation

Development and characterization of an innovtive heparin coating to stabilize and protect liposomes against adverse immune reactions

Duehrkop, Claudia; Leneweit, Gero; Heyder, Christoph; Fromell, Karin et al.

Ingår i Colloids and Surfaces B, s. 576-583, 2016.

DOI för Development and characterization of an innovtive heparin coating to stabilize and protect liposomes against adverse immune reactions

Evidence of contact activation in patients suffering from ST-elevation myocardial infarction

Christensen, Kjeld; Kozarcanin, Huda; Ekdahl, Kristina N.; Nilsson, Bo

Ingår i Thrombosis Research, s. 158-162, 2016.

DOI för Evidence of contact activation in patients suffering from ST-elevation myocardial infarction

Heparinization of cell surfaces with short pepetide-conjugated PEG-lipid regulates thromboinflammation in thransplantation of human MSCs and hepatocytes

Asif, Sana; Ekdahl, Kristina N; Fromell, Karin; Gustafson, Elisabet et al.

Ingår i Acta Biomaterialia, s. 194-205, 2016.

DOI för Heparinization of cell surfaces with short pepetide-conjugated PEG-lipid regulates thromboinflammation in thransplantation of human MSCs and hepatocytes

Multifunctional Hyaluronic Acid and Chondroitin Sulfate Nanoparticles: Impact of Glycosaminoglycan Presentation on Receptor Mediated Cellular Uptake and Immune Activation

Oommen, Oommen Podiyan; Duehrkop, Claudia; Nilsson, Bo; Hilborn, Jöns et al.

Ingår i ACS Applied Materials and Interfaces, s. 20614-20624, 2016.

DOI för Multifunctional Hyaluronic Acid and Chondroitin Sulfate Nanoparticles: Impact of Glycosaminoglycan Presentation on Receptor Mediated Cellular Uptake and Immune Activation

Reciprocal relationship between contact and complement system activation on artificial polymers exposed to whole human blood

Huang, Shan; Engberg, Anna E.; Jonsson, Nina; Sandholm, Kerstin et al.

Ingår i Biomaterials, s. 111-119, 2016.

DOI för Reciprocal relationship between contact and complement system activation on artificial polymers exposed to whole human blood

The lectin complement pathway inhibitor MAP-1 is an upstream regulator of the coagulation cascade

Skjoedt, Mikkel-Ole; Pavlov, Vasile; Kozarcanin, Huda; Willer, Anton et al.

Ingår i Immunobiology, s. 1209-1209, 2016.

DOI för The lectin complement pathway inhibitor MAP-1 is an upstream regulator of the coagulation cascade

The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation

Kozarcanin, Huda; Lood, Christian; Munthe-Fog, Lea; Sandholm, Kerstin et al.

Ingår i Journal of Thrombosis and Haemostasis, s. 531-545, 2016.

DOI för The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation

Type 1 Diabetes Mellitus Donor Mesenchymal. Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro

Davies, Lindsay C.; Alm, Jessica J.; Heldring, Nina; Moll, Guido et al.

Ingår i Stem Cells Translational Medicine, s. 1485-1495, 2016.

DOI för Type 1 Diabetes Mellitus Donor Mesenchymal. Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro

A novel model for studies of blood-mediated long-term responses to cellular transplants

Hårdstedt, Maria; Lindblom, Susanne; Hong, Jaan; Nilsson, Bo et al.

Ingår i Upsala Journal of Medical Sciences, s. 28-39, 2015.

DOI för A novel model for studies of blood-mediated long-term responses to cellular transplants

Cell Surface Engineering for Regulation of Immune Reactions in Cell Therapy

Teramura, Yuji; Asif, Sana; Nilsson Ekdahl, Kristina; Nilsson, Bo

Ingår i Advances in Experimental Medicine and Biology, s. 189-209, 2015.

DOI för Cell Surface Engineering for Regulation of Immune Reactions in Cell Therapy

Complement and platelets: Mutual interference in the immune network

Speth, Cornelia; Rambach, Guenter; Wuerzner, Reinhard; Lass-Floerl, Cornelia et al.

Ingår i Molecular Immunology, s. 108-118, 2015.

DOI för Complement and platelets: Mutual interference in the immune network

Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

Aeinehband, Shahin; Lindblom, Rickard P F; Al Nimer, Faiez; Vijayaraghavan, Swetha et al.

Ingår i PLOS ONE, 2015.

DOI för Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis Ladda ner fulltext (pdf) av Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response

Lindblom, Rickard P. F.; Berg, Alexander; Strom, Mikael; Aeinehband, Shahin et al.

Ingår i Journal of Neuroinflammation, 2015.

DOI för Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response Ladda ner fulltext (pdf) av Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response