Publikationer i DiVA – Christer Betsholtz

  • Castro, Marco; Laviña, Bàrbara; Ando, Koji; Alvarez-Aznar, Alberto et al.

    CDC42 deletion elicits cerebral vascular malformations via increased MEKK3-dependent KLF4 expression

    Ingår i Circulation Research, s. 1240-1252, 2019.

  • Dias, Mariana Castro; Coisne, Caroline; Lazarevic, Ivana; Baden, Pascale et al.

    Claudin-3-deficient C57BL/6J mice display intact brain barriers

    Ingår i Scientific Reports, 2019.

    Open access
  • Hu, Xuchen; Matsumoto, Ken; Jung, Rachel S.; Weston, Thomas A. et al.

    GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients

    Ingår i eLIFE, 2019.

    Open access
  • van Kuijk, Kim; Kuppe, Christoph; Betsholtz, Christer; Vanlandewijck, Michael et al.

    Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single-cell sequencing

    Ingår i Cardiovascular Research, s. 1705-1715, 2019.

  • Glicksberg, Benjamin S.; Amadori, Letizia; Akers, Nicholas K.; Sukhavasi, Katyayani et al.

    Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits

    Ingår i BMC Medical Genomics, 2019.

    Open access
  • Munk, Anne Sofie; Wang, Wei; Bechet, Nicholas Burdon; Eltanahy, Ahmed M. et al.

    PDGF-B Is Required for Development of the Glymphatic System

    Ingår i Cell reports, s. 2955-+, 2019.

    Open access
  • Ando, Koji; Wang, Weili; Peng, Di; Chiba, Ayano et al.

    Peri-arterial specification of vascular mural cells from naive mesenchyme requires Notch signaling

    Ingår i Development, 2019.

  • Dang, Thanh Chung; Ishii, Yoko; Nguyen, Van De; Yamamoto, Seiji et al.

    Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFR alpha in Adult Brain

    Ingår i Cell reports, s. 1073-1089, 2019.

    Open access
  • Kotini, Maria Paraskevi; Mäe, Maarja Andaloussi; Belting, Heinz-Georg; Betsholtz, Christer et al.

    Sprouting and anastomosis in the Drosophila trachea and the vertebrate vasculature: Similarities and differences in cell behaviour

    Ingår i Vascular pharmacology, s. 8-16, 2019.

  • Vanlandewijck, Michael; He, Liqun; Mäe, Maarja Andaloussi; Andrae, Johanna et al.

    A molecular atlas of cell types and zonation in the brain vasculature

    Ingår i Nature, s. 475-480, 2018.

  • Loganathan, Krishnapriya; Salem Said, Ebtisam; Winterrowd, Emily; Orebrand, Martina et al.

    Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice

    Ingår i PLoS ONE, 2018.

    Open access
  • Betsholtz, Christer

    Cell-cell signaling in blood vessel development and function

    Ingår i EMBO Molecular Medicine, 2018.

    Open access
  • Laviña, Bàrbara; Castro, Marco; Niaudet, Colin; Cruys, Bert et al.

    Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations

    Ingår i Development, 2018.

  • Tannenberg, Philip; Chang, Ya-Ting; Muhl, Lars; Laviña, Bàrbara et al.

    Extracellular retention of PDGF-B directs vascular remodeling in mouse hypoxia-induced pulmonary hypertension

    Ingår i American Journal of Physiology - Lung cellular and Molecular Physiology, s. 1593-1605, 2018.

  • Franzen, Oscar; Ermel, Raili; Sukhavasi, Katyayani; Jain, Rajeev et al.

    Global analysis of A-to-I RNA editing reveals association with common disease variants

    Ingår i PeerJ, 2018.

    Open access
  • Honkura, Naoki; Richards, Mark; Laviña, Bàrbara; Sainz-Jaspeado, Miguel et al.

    Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events

    Ingår i Nature Communications, 2018.

    Open access
  • Kuppe, Christoph; Rohlfs, Wilko; Grepl, Martin; Schulte, Kevin et al.

    Inverse correlation between vascular endothelial growth factor back-filtration and capillary filtration pressures

    Ingår i Nephrology, Dialysis and Transplantation, s. 1514-1525, 2018.

  • Bovay, Esther; Sabine, Amelie; Prat-Luri, Borja; Kim, Sudong et al.

    Multiple roles of lymphatic vessels in peripheral lymph node development

    Ingår i Journal of Experimental Medicine, s. 2760-2777, 2018.

  • Gouveia, Leonor; Betsholtz, Christer; Andrae, Johanna

    PDGF-A signaling is required for secondary alveolar septation and controls epithelial proliferation in the developing lung

    Ingår i Development, 2018.

  • Mihajlica, Nebojsa; Betsholtz, Christer; Hammarlund-Udenaes, Margareta

    Pharmacokinetics of Pericyte Involvement in Small-Molecular Drug Transport Across the Blood-Brain Barrier

    Ingår i European Journal of Pharmaceutical Sciences, s. 77-84, 2018.

  • Mäe, Maarja Andaloussi; Li, Tian; Bertuzzi, Giacomo; Raschperger, Elisabeth et al.

    Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier

    Ingår i Scientific Reports, 2018.

    Open access
  • Mihajlica, Nebojsa; Betsholtz, Christer; Hammarlund-Udenaes, Margareta

    Rate of Small-Molecular Drug Transport Across the Blood-Brain Barrier in a Pericyte-Deficient State

    Ingår i European Journal of Pharmaceutical Sciences, s. 182-187, 2018.

  • He, Liqun; Vanlandewijck, Michael; Mäe, Maarja Andaloussi; Andrae, Johanna et al.

    Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

    Ingår i Scientific Data, 2018.

    Open access
  • Jung, Bongnam; Arnold, Thomas D.; Raschperger, Elisabeth; Gaengel, Konstantin et al.

    Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice

    Ingår i Journal of Cerebral Blood Flow and Metabolism, s. 456-468, 2018.

    Open access
  • Dias, Mariana; Coisne, Caroline; Baden, Pascale; Lazarevic, Ivana et al.

    Claudin 3-Deficient C57BL/6 Mice Display Intact Brain Barriers

    Ingår i Journal of Vascular Research, s. 63-63, 2017.

  • Jin, Yi; Muhl, Lars; Burmakin, Mikhail; Wang, Yixin et al.

    Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling

    Ingår i Nature Cell Biology, s. 639-652, 2017.

  • Gouveia, Leonor; Betsholtz, Christer; Andrae, Johanna

    Expression analysis of platelet-derived growth factor receptor alpha and its ligands in the developing mouse lung

    Ingår i Physiological Reports, 2017.

    Open access
  • Jones, Gregory T.; Tromp, Gerard; Kuivaniemi, Helena; Gretarsdottir, Solveig et al.

    Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

    Ingår i Circulation Research, s. 341-+, 2017.

    Open access
  • Andrae, Johanna; Betsholtz, Christer; Gouveia, Maria Leonor Seguardo

    PDGFR alpha signaling is required for alveolar development in the mouse lung

    Ingår i Mechanisms of Development, s. S147-S147, 2017.

  • Guzman, A.; Lange, S.; Silva, M. E.; Gonzalez, G. A. et al.

    Pericytes promote the generation of oligodendrocytes during remyelination

    Ingår i Glia, s. E541-E542, 2017.

  • De La Fuente, Alerie Guzman; Lange, Simona; Silva, Maria Elena; Gonzalez, Ginez A. et al.

    Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination

    Ingår i Cell reports, s. 1755-1764, 2017.

  • Wang, Yixin; Jin, Yi; Mäe, Maarja Andaloussi; Zhang, Yang et al.

    Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity

    Ingår i Development, s. 3590-3601, 2017.

  • Webb, Thomas R.; Erdmann, Jeanette; Stirrups, Kathleen E.; Stitziel, Nathan O. et al.

    Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

    Ingår i Journal of the American College of Cardiology, s. 823-836, 2017.

    Open access
  • Keller, A.; Zarb, Y.; Johannson, B.; Betsholtz, Christer et al.

    The role of microglia in microvascular calcification in the brain

    Ingår i Glia, s. E509-E509, 2017.

  • Liu, Peidi; Lassen, Emelie; Nair, Viji; Berthier, Celine C. et al.

    Transcriptomic and Proteomic Profiling Provides Insight into Mesangial Cell Function in IgA Nephropathy

    Ingår i Journal of the American Society of Nephrology, s. 2961-2972, 2017.

  • Ishibashi, Ryoichi; Takemoto, Minoru; Akimoto, Yoshihiro; Ishikawa, Takahiro et al.

    A novel podocyte gene, semaphorin 3G, protects glomerular podocyte from lipopolysaccharide-induced inflammation

    Ingår i Scientific Reports, 2016.

    Open access
  • Andrae, Johanna; Gouveia, Leonor; Gallini, Radiosa; He, Liqun et al.

    A role for PDGF-C/PDGFR alpha signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex

    Ingår i BIOLOGY OPEN, s. 461-474, 2016.

    Open access
  • Kusumbe, Anjali P.; Ramasamy, Saravana K.; Itkin, Tomer; Mae, Maarja Andaloussi et al.

    Age-dependent modulation of vascular niches for haematopoietic stem cells

    Ingår i Nature, s. 380-+, 2016.

  • Tobin, Nicholas P.; Wennmalm, Kristian; Lindstrom, Linda S.; Foukakis, Theodoros et al.

    An Endothelial Gene Signature Score Predicts Poor Outcome in Patients with Endocrine-Treated, Low Genomic Grade Breast Tumors

    Ingår i Clinical Cancer Research, s. 2417-2426, 2016.

  • He, Liqun; Vanlandewijck, Michael; Raschperger, Elisabeth; Mae, Maarja Andaloussi et al.

    Analysis of the brain mural cell transcriptome

    Ingår i Scientific Reports, 2016.

    Open access
  • Miller, Clint L.; Pjanic, Milos; Wang, Ting; Nguyen, Trieu et al.

    Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci

    Ingår i Nature Communications, 2016.

    Open access
  • Gallini, Radiosa; Huusko, Jenni; Yla-Herttuala, Seppo; Betsholtz, Christer et al.

    Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart

    Ingår i PLoS ONE, 2016.

    Open access
  • Tannenberg, P.; Folestad, E.; Chang, Y. -T; Gladh, H. et al.

    Lack Of Pdgf-B Retention Ameliorates Hypoxia-Induced Pulmonary Hypertension

    Ingår i American Journal of Respiratory and Critical Care Medicine, 2016.

  • Gladh, Hanna; Folestad, Erika Bergsten; Muhl, Lars; Ehnman, Monika et al.

    Mice Lacking Platelet-Derived Growth Factor D Display a Mild Vascular Phenotype

    Ingår i PLoS ONE, 2016.

    Open access
  • Dejana, Elisabetta; Betsholtz, Christer

    Oligodendrocytes follow blood vessel trails in the brain Brain microvasculature is a scaffold for neuroglial migration

    Ingår i Science, s. 341-342, 2016.

  • Gallini, Radiosa; Lindblom, Per; Bondjers, Cecilia; Betsholtz, Christer et al.

    PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice

    Ingår i Experimental Cell Research, s. 282-290, 2016.

    Open access
  • Rivera-Gonzalez, Guillermo C.; Shook, Brett A.; Andrae, Johanna; Holtrup, Brandon et al.

    Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis

    Ingår i Cell Stem Cell, s. 738-751, 2016.

  • Villasenor, Roberto; Ozmen, Laurence; Messaddeq, Nadia; Gruninger, Fiona et al.

    Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier

    Ingår i Scientific Reports, 2016.

    Open access
  • Betsholtz, Christer

    Transcriptional control of endothelial energy

    Ingår i Nature, s. 160-161, 2016.

  • Li, Xiujuan; Padhan, Narendra; Sjöström, Elisabet O.; Roche, Francis P. et al.

    VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread

    Ingår i Nature Communications, 2016.

    Open access
  • Zeisel, Amit; Munoz-Manchado, Ana B.; Codeluppi, Simone; Lonnerberg, Peter et al.

    Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

    Ingår i Science, s. 1138-1142, 2015.

  • Stanczuk, Lukas; Martinez-Corral, Ines; Ulvmar, Maria H.; Zhang, Yang et al.

    cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels

    Ingår i Cell reports, s. 1708-1721, 2015.

    Open access
  • Zhao, Zhen; Nelson, Amy R.; Betsholtz, Christer; Zlokovic, Berislav V.

    Establishment and Dysfunction of the Blood-Brain Barrier

    Ingår i Cell, s. 1064-1078, 2015.

  • Vanlandewijck, Michael; Lebouvier, Thibaud; Mae, Maarja Andaloussi; Nahar, Khayrun et al.

    Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification

    Ingår i PLoS ONE, 2015.

    Open access
  • Niaudet, Colin; Hofmann, Jennifer J.; Mae, Maarja A.; Jung, Bongnam et al.

    Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium

    Ingår i PLoS ONE, 2015.

    Open access
  • Rodriguez, Patricia Q.; Oddsson, Asmundur; Ebarasi, Lwaki; He, Bing et al.

    Knockdown of Tmem234 in zebrafish results in proteinuria

    Ingår i AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, s. F955-F966, 2015.

  • Betsholtz, Christer

    Lipid transport and human brain development

    Ingår i Nature Genetics, s. 699-701, 2015.

  • Henshall, Tanya L; Keller, Annika; He, Liqun; Johansson, Bengt R et al.

    Notch3 Is Necessary for Blood Vessel Integrity in the Central Nervous System

    Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 409-420, 2015.

  • Kok, Fatma O.; Shin, Masahiro; Ni, Chih-Wen; Gupta, Ankit et al.

    Reverse Genetic Screening Reveals Poor Correlation between Morpholino-Induced and Mutant Phenotypes in Zebrafish

    Ingår i Developmental Cell, s. 97-108, 2015.

  • Ishikawa, T.; Takemoto, M.; Akimoto, Y.; Yan, K. et al.

    A novel podocyte gene, R3h domain containing-like inhibits non-canonical TGF-beta signalling

    Ingår i Diabetologia, s. S44-S44, 2014.

  • Betsholtz, Christer

    Double function at the blood-brain barrier

    Ingår i Nature, s. 432-433, 2014.

  • He, Bing; Ebarasi, Lwaki; Zhao, Zhe; Guo, Jing et al.

    Lmx1b and FoxC Combinatorially Regulate Podocin Expression in Podocytes

    Ingår i Journal of the American Society of Nephrology, s. 2764-2777, 2014.

  • Betsholtz, Christer; Keller, Annika

    PDGF, Pericytes and the Pathogenesis of Idiopathic Basal Ganglia Calcification (IBGC)

    Ingår i Brain Pathology, s. 387-395, 2014.

  • Andrae, Johanna; Ehrencrona, Hans; Gallini, Radiosa; Lal, Mark et al.

    Analysis of Mice Lacking the Heparin-Binding Splice Isoform of Platelet-Derived Growth Factor A

    Ingår i Molecular and Cellular Biology, s. 4030-4040, 2013.

  • Gängel, Konstantin; Betsholtz, Christer

    Endocytosis regulates VEGF signalling during angiogenesis

    Ingår i Nature Cell Biology, s. 233-235, 2013.

  • Keller, Annika; Westenberger, Ana; Sobrido, Maria J.; Garcia-Murias, Maria et al.

    Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice

    Ingår i Nature Genetics, s. 1077-+, 2013.

  • Henderson, Neil C.; Arnold, Thomas D.; Katamura, Yoshio; Giacomini, Marilyn M. et al.

    Targeting of alpha(v) integrin identifies a core molecular pathway that regulates fibrosis in several organs

    Ingår i Nature Medicine, s. 1617-1624, 2013.

  • Xiao, Zhijie; Rodriguez, Patricia Q.; He, Liqun; Betsholtz, Christer et al.

    Wtip- and Gadd45a-Interacting Protein Dendrin Is Not Crucial for the Development or Maintenance of the Glomerular Filtration Barrier

    Ingår i PLoS ONE, s. e83133-, 2013.

    Open access
  • Furuhashi, Masao; Sjöblom, Tobias; Abramsson, Alexandra; Ellingsen, Jens et al.

    Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate

    Ingår i Cancer Research, s. 2725-2733, 2004.