Publikationer i DiVA – Christer Betsholtz
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Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation
Ingår i Journal of Experimental Medicine, 2023.
DOI för Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation Ladda ner fulltext (pdf) av Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation
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The role of dendrin in IgA nephropathy
Ingår i Nephrology, Dialysis and Transplantation, s. 311-321, 2023.
DOI för The role of dendrin in IgA nephropathy Ladda ner fulltext (pdf) av The role of dendrin in IgA nephropathy
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ADAMTS18+ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels
Ingår i Nature Communications, 2022.
DOI för ADAMTS18+ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels Ladda ner fulltext (pdf) av ADAMTS18+ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels
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Adult-induced genetic ablation distinguishes PDGFB roles in blood-brain barrier maintenance and development
Ingår i Journal of Cerebral Blood Flow and Metabolism, s. 264-279, 2022.
DOI för Adult-induced genetic ablation distinguishes PDGFB roles in blood-brain barrier maintenance and development Ladda ner fulltext (pdf) av Adult-induced genetic ablation distinguishes PDGFB roles in blood-brain barrier maintenance and development
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An overlooked subset of Cx3cr1(wt/wt) microglia in the Cx3cr1(CreER-Eyfp/wt) mouse has a repopulation advantage over Cx3cr1(CreER-Eyfp/wt) microglia following microglial depletion
Ingår i Journal of Neuroinflammation, 2022.
DOI för An overlooked subset of Cx3cr1(wt/wt) microglia in the Cx3cr1(CreER-Eyfp/wt) mouse has a repopulation advantage over Cx3cr1(CreER-Eyfp/wt) microglia following microglial depletion Ladda ner fulltext (pdf) av An overlooked subset of Cx3cr1(wt/wt) microglia in the Cx3cr1(CreER-Eyfp/wt) mouse has a repopulation advantage over Cx3cr1(CreER-Eyfp/wt) microglia following microglial depletion
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Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation: A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients
Ingår i Biomedicines, 2022.
DOI för Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation: A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients Ladda ner fulltext (pdf) av Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation: A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients
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Cellular Origin of Sporadic CCMs
Ingår i New England Journal of Medicine, s. 1291-1291, 2022.
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Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner
Ingår i eLIFE, 2022.
DOI för Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner Ladda ner fulltext (pdf) av Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner
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Microvascular stabilization via blood-brain barrier regulation prevents seizure activity
Ingår i Nature Communications, 2022.
DOI för Microvascular stabilization via blood-brain barrier regulation prevents seizure activity Ladda ner fulltext (pdf) av Microvascular stabilization via blood-brain barrier regulation prevents seizure activity
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Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow
Ingår i Circulation Research, s. 308-327, 2022.
DOI för Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow Ladda ner fulltext (pdf) av Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow
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PDGFR beta(+) cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny
Ingår i Cell reports, 2022.
DOI för PDGFR beta(+) cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny Ladda ner fulltext (pdf) av PDGFR beta(+) cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny
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Proper migration of lymphatic endothelial cells requires survival and guidance cues from arterial mural cells
Ingår i eLIFE, 2022.
DOI för Proper migration of lymphatic endothelial cells requires survival and guidance cues from arterial mural cells Ladda ner fulltext (pdf) av Proper migration of lymphatic endothelial cells requires survival and guidance cues from arterial mural cells
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Semaphorin 3G exacerbates joint inflammation through the accumulation and proliferation of macrophages in the synovium
Ingår i Arthritis Research & Therapy, 2022.
DOI för Semaphorin 3G exacerbates joint inflammation through the accumulation and proliferation of macrophages in the synovium Ladda ner fulltext (pdf) av Semaphorin 3G exacerbates joint inflammation through the accumulation and proliferation of macrophages in the synovium
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Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFR alpha signalling in cerebellar development
Ingår i BIOLOGY OPEN, 2022.
DOI för Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFR alpha signalling in cerebellar development Ladda ner fulltext (pdf) av Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFR alpha signalling in cerebellar development
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The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research
Ingår i Stem Cell Reports, s. 1089-1104, 2022.
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Toward a granular molecular-anatomic map of the blood vasculature - single-cell RNA sequencing makes the leap
Ingår i Upsala Journal of Medical Sciences, 2022.
DOI för Toward a granular molecular-anatomic map of the blood vasculature - single-cell RNA sequencing makes the leap Ladda ner fulltext (pdf) av Toward a granular molecular-anatomic map of the blood vasculature - single-cell RNA sequencing makes the leap
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A human cell type similar to murine central nervous system perivascular fibroblasts
Ingår i Experimental Cell Research, 2021.
DOI för A human cell type similar to murine central nervous system perivascular fibroblasts Ladda ner fulltext (pdf) av A human cell type similar to murine central nervous system perivascular fibroblasts
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A novel podocyte protein, R3h domain containing-like, inhibits TGF-β-induced p38 MAPK and regulates the structure of podocytes and glomerular basement membrane
Ingår i Journal of Molecular Medicine, s. 859-876, 2021.
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A Switch from Cell-Associated to Soluble PDGF-B Protects against Atherosclerosis, despite Driving Extramedullary Hematopoiesis
Ingår i Cells, s. 1746-, 2021.
DOI för A Switch from Cell-Associated to Soluble PDGF-B Protects against Atherosclerosis, despite Driving Extramedullary Hematopoiesis Ladda ner fulltext (pdf) av A Switch from Cell-Associated to Soluble PDGF-B Protects against Atherosclerosis, despite Driving Extramedullary Hematopoiesis
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ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.
Ingår i Neuro-Oncology, s. 398-411, 2021.
DOI för ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma. Ladda ner fulltext (pdf) av ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.
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Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing
Ingår i JCI Insight, 2021.
DOI för Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing Ladda ner fulltext (pdf) av Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing
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Lack of Evidence of Angiotensin-Converting Enzyme 2 Expression and Replicative Infection by SARS-CoV-2 in Human Endothelial Cells
Ingår i Circulation, s. 865-868, 2021.
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Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss
Ingår i Circulation Research, s. E46-E62, 2021.
DOI för Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss
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Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes
Ingår i Nature Communications, 2021.
DOI för Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes Ladda ner fulltext (pdf) av Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes
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The infantile myofibromatosis NOTCH3 L1519P mutation leads to hyperactivated ligand-independent Notch signaling and increased PDGFRB expression
Ingår i Disease Models and Mechanisms, 2021.
DOI för The infantile myofibromatosis NOTCH3 L1519P mutation leads to hyperactivated ligand-independent Notch signaling and increased PDGFRB expression Ladda ner fulltext (pdf) av The infantile myofibromatosis NOTCH3 L1519P mutation leads to hyperactivated ligand-independent Notch signaling and increased PDGFRB expression
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Vascular PDGFR-alpha protects against BBB dysfunction after stroke in mice
Ingår i Angiogenesis, s. 35-46, 2021.
DOI för Vascular PDGFR-alpha protects against BBB dysfunction after stroke in mice
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VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration
Ingår i Circulation, s. 65-77, 2021.
DOI för VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration Ladda ner fulltext (pdf) av VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration
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Astrocyte-microglial association and matrix composition are common events in the natural history of primary familial brain calcification
Ingår i Brain Pathology, s. 446-464, 2020.
DOI för Astrocyte-microglial association and matrix composition are common events in the natural history of primary familial brain calcification Ladda ner fulltext (pdf) av Astrocyte-microglial association and matrix composition are common events in the natural history of primary familial brain calcification
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Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier
Ingår i Journal of Clinical Investigation, s. 4055-4068, 2020.
DOI för Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier
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Lung developmental arrest caused by PDGF-A deletion: consequences for the adult mouse lung
Ingår i American Journal of Physiology - Lung cellular and Molecular Physiology, s. L831-L843, 2020.
DOI för Lung developmental arrest caused by PDGF-A deletion: consequences for the adult mouse lung
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Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis
Ingår i International Journal of Cancer, s. 2634-2644, 2020.
DOI för Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis Ladda ner fulltext (pdf) av Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis
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Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis
Ingår i Cancer Research, s. 3345-3358, 2020.
DOI för Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis
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Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain
Ingår i Cell reports, 2020.
DOI för Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain Ladda ner fulltext (pdf) av Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain
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Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis
Ingår i Nature Communications, 2020.
DOI för Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis Ladda ner fulltext (pdf) av Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis
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Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
Ingår i eLIFE, 2020.
DOI för Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta Ladda ner fulltext (pdf) av Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
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Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreER(T2) lines
Ingår i Transgenic research, s. 53-68, 2020.
DOI för Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreER(T2) lines Ladda ner fulltext (pdf) av Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreER(T2) lines
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GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients
Ingår i eLIFE, 2019.
DOI för GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients Ladda ner fulltext (pdf) av GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients
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Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits
Ingår i BMC Medical Genomics, 2019.
DOI för Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits Ladda ner fulltext (pdf) av Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits
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Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFR alpha in Adult Brain
Ingår i Cell reports, s. 1073-1089, 2019.
DOI för Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFR alpha in Adult Brain Ladda ner fulltext (pdf) av Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFR alpha in Adult Brain
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Sprouting and anastomosis in the Drosophila trachea and the vertebrate vasculature: Similarities and differences in cell behaviour
Ingår i Vascular pharmacology, s. 8-16, 2019.
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Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice
Ingår i PLOS ONE, 2018.
DOI för Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice Ladda ner fulltext (pdf) av Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice
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Extracellular retention of PDGF-B directs vascular remodeling in mouse hypoxia-induced pulmonary hypertension
Ingår i American Journal of Physiology - Lung cellular and Molecular Physiology, s. 1593-1605, 2018.
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Global analysis of A-to-I RNA editing reveals association with common disease variants
Ingår i PeerJ, 2018.
DOI för Global analysis of A-to-I RNA editing reveals association with common disease variants Ladda ner fulltext (pdf) av Global analysis of A-to-I RNA editing reveals association with common disease variants
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Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events
Ingår i Nature Communications, 2018.
DOI för Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events Ladda ner fulltext (pdf) av Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events
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Inverse correlation between vascular endothelial growth factor back-filtration and capillary filtration pressures
Ingår i Nephrology, Dialysis and Transplantation, s. 1514-1525, 2018.
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Multiple roles of lymphatic vessels in peripheral lymph node development
Ingår i Journal of Experimental Medicine, s. 2760-2777, 2018.
DOI för Multiple roles of lymphatic vessels in peripheral lymph node development
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Pharmacokinetics of Pericyte Involvement in Small-Molecular Drug Transport Across the Blood-Brain Barrier
Ingår i European Journal of Pharmaceutical Sciences, s. 77-84, 2018.
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Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier
Ingår i Scientific Reports, 2018.
DOI för Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier Ladda ner fulltext (pdf) av Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier
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Rate of Small-Molecular Drug Transport Across the Blood-Brain Barrier in a Pericyte-Deficient State
Ingår i European Journal of Pharmaceutical Sciences, s. 182-187, 2018.
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Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types
Ingår i Scientific Data, 2018.
DOI för Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types Ladda ner fulltext (pdf) av Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types
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Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice
Ingår i Journal of Cerebral Blood Flow and Metabolism, s. 456-468, 2018.
DOI för Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice Ladda ner fulltext (pdf) av Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice
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Claudin 3-Deficient C57BL/6 Mice Display Intact Brain Barriers
Ingår i Journal of Vascular Research, s. 63-63, 2017.
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Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling
Ingår i Nature Cell Biology, s. 639-652, 2017.
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Expression analysis of platelet-derived growth factor receptor alpha and its ligands in the developing mouse lung
Ingår i Physiological Reports, 2017.
DOI för Expression analysis of platelet-derived growth factor receptor alpha and its ligands in the developing mouse lung Ladda ner fulltext (pdf) av Expression analysis of platelet-derived growth factor receptor alpha and its ligands in the developing mouse lung
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Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci
Ingår i Circulation Research, s. 341-+, 2017.
DOI för Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci Ladda ner fulltext (pdf) av Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci
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PDGFR alpha signaling is required for alveolar development in the mouse lung
Ingår i Mechanisms of Development, s. S147-S147, 2017.
DOI för PDGFR alpha signaling is required for alveolar development in the mouse lung
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Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease
Ingår i Journal of the American College of Cardiology, s. 823-836, 2017.
DOI för Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease Ladda ner fulltext (pdf) av Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease
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The role of microglia in microvascular calcification in the brain
Ingår i Glia, s. E509-E509, 2017.
DOI för The role of microglia in microvascular calcification in the brain
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Transcriptomic and Proteomic Profiling Provides Insight into Mesangial Cell Function in IgA Nephropathy
Ingår i Journal of the American Society of Nephrology, s. 2961-2972, 2017.
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A novel podocyte gene, semaphorin 3G, protects glomerular podocyte from lipopolysaccharide-induced inflammation
Ingår i Scientific Reports, 2016.
DOI för A novel podocyte gene, semaphorin 3G, protects glomerular podocyte from lipopolysaccharide-induced inflammation Ladda ner fulltext (pdf) av A novel podocyte gene, semaphorin 3G, protects glomerular podocyte from lipopolysaccharide-induced inflammation
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A role for PDGF-C/PDGFR alpha signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex
Ingår i BIOLOGY OPEN, s. 461-474, 2016.
DOI för A role for PDGF-C/PDGFR alpha signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex Ladda ner fulltext (pdf) av A role for PDGF-C/PDGFR alpha signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex
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An Endothelial Gene Signature Score Predicts Poor Outcome in Patients with Endocrine-Treated, Low Genomic Grade Breast Tumors
Ingår i Clinical Cancer Research, s. 2417-2426, 2016.
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Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci
Ingår i Nature Communications, 2016.
DOI för Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci Ladda ner fulltext (pdf) av Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci
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Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart
Ingår i PLOS ONE, 2016.
DOI för Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart Ladda ner fulltext (pdf) av Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart
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Lack Of Pdgf-B Retention Ameliorates Hypoxia-Induced Pulmonary Hypertension
Ingår i American Journal of Respiratory and Critical Care Medicine, 2016.
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PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice
Ingår i Experimental Cell Research, s. 282-290, 2016.
DOI för PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice Ladda ner fulltext (pdf) av PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice
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Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis
Ingår i Cell Stem Cell, s. 738-751, 2016.
DOI för Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis
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Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier
Ingår i Scientific Reports, 2016.
DOI för Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier Ladda ner fulltext (pdf) av Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier
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Transcriptional control of endothelial energy
Ingår i Nature, s. 160-161, 2016.
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VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread
Ingår i Nature Communications, 2016.
DOI för VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread Ladda ner fulltext (pdf) av VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread