Publikationer i DiVA – Christer Betsholtz

A single-cell transcriptomic inventory of murine smooth muscle cells

Muhl, Lars; Mocci, Giuseppe; Pietilä, Riikka; Liu, Jianping et al.

Ingår i Developmental Cell, s. 2426-+, 2022.

DOI för A single-cell transcriptomic inventory of murine smooth muscle cells Ladda ner fulltext (pdf) av A single-cell transcriptomic inventory of murine smooth muscle cells

ADAMTS18⁺ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels

Bernier-Latmani, Jeremiah; Mauri, Cristina; Marcone, Rachel; Renevey, Francois et al.

Ingår i Nature Communications, 2022.

DOI för ADAMTS18⁺ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels Ladda ner fulltext (pdf) av ADAMTS18⁺ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels

Adult-induced genetic ablation distinguishes PDGFB roles in blood-brain barrier maintenance and development

Vazquez-Liebanas, Elisa; Nahar, Khayrun; Bertuzzi, Giacomo; Keller, Annika et al.

Ingår i Journal of Cerebral Blood Flow and Metabolism, s. 264-279, 2022.

DOI för Adult-induced genetic ablation distinguishes PDGFB roles in blood-brain barrier maintenance and development Ladda ner fulltext (pdf) av Adult-induced genetic ablation distinguishes PDGFB roles in blood-brain barrier maintenance and development

An overlooked subset of Cx3cr1(wt/wt) microglia in the Cx3cr1(CreER-Eyfp/wt) mouse has a repopulation advantage over Cx3cr1(CreER-Eyfp/wt) microglia following microglial depletion

Zhou, Kai; Han, Jinming; Lund, Harald; Boggavarapu, Nageswara Rao et al.

Ingår i Journal of Neuroinflammation, 2022.

DOI för An overlooked subset of Cx3cr1(wt/wt) microglia in the Cx3cr1(CreER-Eyfp/wt) mouse has a repopulation advantage over Cx3cr1(CreER-Eyfp/wt) microglia following microglial depletion Ladda ner fulltext (pdf) av An overlooked subset of Cx3cr1(wt/wt) microglia in the Cx3cr1(CreER-Eyfp/wt) mouse has a repopulation advantage over Cx3cr1(CreER-Eyfp/wt) microglia following microglial depletion

Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation: A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients

Hultström, Michael; Fromell, Karin; Larsson, Anders; Persson, Barbro et al.

Ingår i Biomedicines, 2022.

DOI för Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation: A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients Ladda ner fulltext (pdf) av Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation: A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients

Cellular Origin of Sporadic CCMs

Betsholtz, Christer; Gängel, Konstantin; Mäkinen, Taija

Ingår i New England Journal of Medicine, s. 1291-1291, 2022.

DOI för Cellular Origin of Sporadic CCMs

Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner

Richards, Mark; Nwadozi, Emmanuel; Pal, Sagnik; Martinsson, Pernilla et al.

Ingår i eLIFE, 2022.

DOI för Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner Ladda ner fulltext (pdf) av Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner

Identification, discrimination and heterogeneity of fibroblasts

Lendahl, Urban; Muhl, Lars; Betsholtz, Christer

Ingår i Nature Communications, 2022.

DOI för Identification, discrimination and heterogeneity of fibroblasts Ladda ner fulltext (pdf) av Identification, discrimination and heterogeneity of fibroblasts

KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling

Ando, Koji; Tong, Lei; Peng, Di; Vazquez-Liebanas, Elisa et al.

Ingår i Developmental Cell, s. 1383-1399.e7, 2022.

DOI för KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling

Microvascular stabilization via blood-brain barrier regulation prevents seizure activity

Greene, Chris; Hanley, Nicole; Reschke, Cristina R.; Reddy, Avril et al.

Ingår i Nature Communications, 2022.

DOI för Microvascular stabilization via blood-brain barrier regulation prevents seizure activity Ladda ner fulltext (pdf) av Microvascular stabilization via blood-brain barrier regulation prevents seizure activity

Molecular insights into the early stage of glomerular injury in IgA nephropathy using single-cell RNA sequencing

Zambrano, Sonia; He, Liqun; Kano, Toshiki; Sun, Ying et al.

Ingår i Kidney International, s. 752-765, 2022.

DOI för Molecular insights into the early stage of glomerular injury in IgA nephropathy using single-cell RNA sequencing

Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow

Orlich, Michael M.; Dieguez-Hurtado, Rodrigo; Muehlfriedel, Regine; Sothilingam, Vithiyanjali et al.

Ingår i Circulation Research, s. 308-327, 2022.

DOI för Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow Ladda ner fulltext (pdf) av Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow

PDGFR beta(+) cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny

da Bandeira, Diana Sa; Kilpatrick, Alastair Morris; Marques, Madalena; Gomez-Salazar, Mario et al.

Ingår i Cell reports, 2022.

DOI för PDGFR beta(+) cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny Ladda ner fulltext (pdf) av PDGFR beta(+) cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny

Proper migration of lymphatic endothelial cells requires survival and guidance cues from arterial mural cells

Peng, Di; Ando, Koji; Hussmann, Melina; Gloger, Marleen et al.

Ingår i eLIFE, 2022.

DOI för Proper migration of lymphatic endothelial cells requires survival and guidance cues from arterial mural cells Ladda ner fulltext (pdf) av Proper migration of lymphatic endothelial cells requires survival and guidance cues from arterial mural cells

Semaphorin 3G exacerbates joint inflammation through the accumulation and proliferation of macrophages in the synovium

Shoda, Jumpei; Tanaka, Shigeru; Etori, Keishi; Hattori, Koto et al.

Ingår i Arthritis Research & Therapy, 2022.

DOI för Semaphorin 3G exacerbates joint inflammation through the accumulation and proliferation of macrophages in the synovium Ladda ner fulltext (pdf) av Semaphorin 3G exacerbates joint inflammation through the accumulation and proliferation of macrophages in the synovium

Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFR alpha signalling in cerebellar development

Gillnäs, Sara; Gallini, Radiosa; He, Liqun; Betsholtz, Christer et al.

Ingår i BIOLOGY OPEN, 2022.

DOI för Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFR alpha signalling in cerebellar development Ladda ner fulltext (pdf) av Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFR alpha signalling in cerebellar development

Specification of CNS macrophage subsets occurs postnatally in defined niches

Masuda, Takahiro; Amann, Lukas; Monaco, Gianni; Sankowski, Roman et al.

Ingår i Nature, s. 740-+, 2022.

DOI för Specification of CNS macrophage subsets occurs postnatally in defined niches

The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research

Muhl, Lars; He, Liqun; Sun, Ying; Andaloussi Mäe, Maarja et al.

Ingår i Stem Cell Reports, s. 1089-1104, 2022.

DOI för The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research

Toward a granular molecular-anatomic map of the blood vasculature - single-cell RNA sequencing makes the leap

Betsholtz, Christer

Ingår i Upsala Journal of Medical Sciences, 2022.

DOI för Toward a granular molecular-anatomic map of the blood vasculature - single-cell RNA sequencing makes the leap Ladda ner fulltext (pdf) av Toward a granular molecular-anatomic map of the blood vasculature - single-cell RNA sequencing makes the leap

A human cell type similar to murine central nervous system perivascular fibroblasts

Liu, Jianping; He, Liqun; Muhl, Lars; Mocci, Giuseppe et al.

Ingår i Experimental Cell Research, 2021.

DOI för A human cell type similar to murine central nervous system perivascular fibroblasts Ladda ner fulltext (pdf) av A human cell type similar to murine central nervous system perivascular fibroblasts

A novel podocyte protein, R3h domain containing-like, inhibits TGF-β-induced p38 MAPK and regulates the structure of podocytes and glomerular basement membrane

Ishikawa, Takahiro; Takemoto, Minoru; Akimoto, Yoshihiro; Takada-Watanabe, Aki et al.

Ingår i Journal of Molecular Medicine, s. 859-876, 2021.

DOI för A novel podocyte protein, R3h domain containing-like, inhibits TGF-β-induced p38 MAPK and regulates the structure of podocytes and glomerular basement membrane

A Switch from Cell-Associated to Soluble PDGF-B Protects against Atherosclerosis, despite Driving Extramedullary Hematopoiesis

Tillie, Renee J. H. A.; Theelen, Thomas L.; van Kuijk, Kim; Temmerman, Lieve et al.

Ingår i Cells, s. 1746-, 2021.

DOI för A Switch from Cell-Associated to Soluble PDGF-B Protects against Atherosclerosis, despite Driving Extramedullary Hematopoiesis Ladda ner fulltext (pdf) av A Switch from Cell-Associated to Soluble PDGF-B Protects against Atherosclerosis, despite Driving Extramedullary Hematopoiesis

Conserved and context-dependent roles for pdgfrb signaling during zebrafish vascular mural cell development

Ando, Koji; Shih, Yu-Huan; Ebarasi, Lwaki; Grosse, Ann et al.

Ingår i Developmental Biology, s. 11-22, 2021.

DOI för Conserved and context-dependent roles for pdgfrb signaling during zebrafish vascular mural cell development

Elevated Angiopoietin-2 inhibits thrombomodulin-mediated anticoagulation in critically ill COVID-19 patients

Hultström, Michael; Fromell, Karin; Larsson, Anders; Quaggin, Susan E et al.

Ingår i medRxiv, s. 1-27, 2021.

DOI för Elevated Angiopoietin-2 inhibits thrombomodulin-mediated anticoagulation in critically ill COVID-19 patients

ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.

Huang, Hua; Georganaki, Maria; Conze, Lei Liu; Laviña, Bàrbara et al.

Ingår i Neuro-Oncology, s. 398-411, 2021.

DOI för ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma. Ladda ner fulltext (pdf) av ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.

Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing

Xie, Yuan; He, Liqun; Lugano, Roberta; Zhang, Yanyu et al.

Ingår i JCI Insight, 2021.

DOI för Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing Ladda ner fulltext (pdf) av Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing

Lack of Evidence of Angiotensin-Converting Enzyme 2 Expression and Replicative Infection by SARS-CoV-2 in Human Endothelial Cells

McCracken, Ian R.; Saginc, Gaye; He, Liqun; Huseynov, Alik et al.

Ingår i Circulation, s. 865-868, 2021.

DOI för Lack of Evidence of Angiotensin-Converting Enzyme 2 Expression and Replicative Infection by SARS-CoV-2 in Human Endothelial Cells

Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss

Mäe, Maarja Andaloussi; He, Liqun; Nordling, Sofia; Vazquez-Liebanas, Elisa et al.

Ingår i Circulation Research, s. E46-E62, 2021.

DOI för Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss

Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes

He, Bing; Chen, Ping; Zambrano, Sonia; Dabaghie, Dina et al.

Ingår i Nature Communications, 2021.

DOI för Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes Ladda ner fulltext (pdf) av Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes

The infantile myofibromatosis NOTCH3 L1519P mutation leads to hyperactivated ligand-independent Notch signaling and increased PDGFRB expression

Wu, Dan; Wang, Sailan; Oliveira, Daniel V.; Del Gaudio, Francesca et al.

Ingår i Disease Models and Mechanisms, 2021.

DOI för The infantile myofibromatosis NOTCH3 L1519P mutation leads to hyperactivated ligand-independent Notch signaling and increased PDGFRB expression Ladda ner fulltext (pdf) av The infantile myofibromatosis NOTCH3 L1519P mutation leads to hyperactivated ligand-independent Notch signaling and increased PDGFRB expression

Vascular PDGFR-alpha protects against BBB dysfunction after stroke in mice

Nguyen, Quang Linh; Okuno, Noriko; Hamashima, Takeru; Dang, Son Tung et al.

Ingår i Angiogenesis, s. 35-46, 2021.

DOI för Vascular PDGFR-alpha protects against BBB dysfunction after stroke in mice

VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration

Räsänen, Markus; Sultan, Ibrahim; Paech, Jennifer; Hemanthakumar, Karthik Amudhala et al.

Ingår i Circulation, s. 65-77, 2021.

DOI för VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration Ladda ner fulltext (pdf) av VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration

Astrocyte-microglial association and matrix composition are common events in the natural history of primary familial brain calcification

Nahar, Khayrun; Lebouvier, Thibaud; Andaloussi Mäe, Maarja; Konzer, Anne et al.

Ingår i Brain Pathology, s. 446-464, 2020.

DOI för Astrocyte-microglial association and matrix composition are common events in the natural history of primary familial brain calcification Ladda ner fulltext (pdf) av Astrocyte-microglial association and matrix composition are common events in the natural history of primary familial brain calcification

Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier

Santander, Nicolas; Lizama, Carlos O.; Meky, Eman; McKinsey, Gabriel L. et al.

Ingår i Journal of Clinical Investigation, s. 4055-4068, 2020.

DOI för Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier

Lung developmental arrest caused by PDGF-A deletion: consequences for the adult mouse lung

Gouveia, Maria Leonor Seguardo; Kraut, Simone; Hadzic, Stefan; Vazquez-Liebanas, Elisa et al.

Ingår i American Journal of Physiology - Lung cellular and Molecular Physiology, s. L831-L843, 2020.

DOI för Lung developmental arrest caused by PDGF-A deletion: consequences for the adult mouse lung

Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis

He, Qi; Li, Xiujuan; He, Liqun; Li, Yousheng et al.

Ingår i International Journal of Cancer, s. 2634-2644, 2020.

DOI för Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis Ladda ner fulltext (pdf) av Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis

Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis

Zhang, Yanyu; Cedervall, Jessica; Hamidi, Anahita; Herre, Melanie et al.

Ingår i Cancer Research, s. 3345-3358, 2020.

DOI för Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis

Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain

Osman, Ahmed M.; Sun, Ying; Burns, Terry C.; He, Liqun et al.

Ingår i Cell reports, 2020.

DOI för Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain Ladda ner fulltext (pdf) av Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain

Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis

Wang, Guangxia; Muhl, Lars; Padberg, Yvonne; Dupont, Laura et al.

Ingår i Nature Communications, 2020.

DOI för Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis Ladda ner fulltext (pdf) av Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis

Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization

Yanagida, Keisuke; Engelbrecht, Eric; Niaudet, Colin; Jung, Bongnam et al.

Ingår i Developmental Cell, s. 779-+, 2020.

DOI för Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization

Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta

Engelbrecht, Eric; Levesque, Michel, V; He, Liqun; Vanlandewijck, Michael et al.

Ingår i eLIFE, 2020.

DOI för Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta Ladda ner fulltext (pdf) av Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta

Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreER(T2) lines

Alvarez, Alberto; Martinez-Corral, Ines; Daubel, Nina; Betsholtz, Christer et al.

Ingår i Transgenic research, s. 53-68, 2020.

DOI för Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreER(T2) lines Ladda ner fulltext (pdf) av Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreER(T2) lines

The Ion Channel and GPCR Toolkit of Brain Capillary Pericytes

Hariharan, Ashwini; Weir, Nick; Robertson, Colin; He, Liqun et al.

Ingår i Frontiers in Cellular Neuroscience, 2020.

DOI för The Ion Channel and GPCR Toolkit of Brain Capillary Pericytes Ladda ner fulltext (pdf) av The Ion Channel and GPCR Toolkit of Brain Capillary Pericytes

Adgrf5 contributes to patterning of the endothelial deep layer in retina

Niaudet, Colin; Petkova, Milena; Jung, Bongnam; Lu, S. et al.

Ingår i Angiogenesis, s. 491-505, 2019.

DOI för Adgrf5 contributes to patterning of the endothelial deep layer in retina Ladda ner fulltext (pdf) av Adgrf5 contributes to patterning of the endothelial deep layer in retina

CDC42 deletion elicits cerebral vascular malformations via increased MEKK3-dependent KLF4 expression

Castro, Marco; Laviña, Bàrbara; Ando, Koji; Alvarez-Aznar, Alberto et al.

Ingår i Circulation Research, s. 1240-1252, 2019.

DOI för CDC42 deletion elicits cerebral vascular malformations via increased MEKK3-dependent KLF4 expression

Claudin-3-deficient C57BL/6J mice display intact brain barriers

Dias, Mariana Castro; Coisne, Caroline; Lazarevic, Ivana; Baden, Pascale et al.

Ingår i Scientific Reports, 2019.

DOI för Claudin-3-deficient C57BL/6J mice display intact brain barriers Ladda ner fulltext (pdf) av Claudin-3-deficient C57BL/6J mice display intact brain barriers

Emerging links between cerebrovascular and neurodegenerative diseases-a special role for pericytes

Lendahl, Urban; Nilsson, Per; Betsholtz, Christer

Ingår i EMBO Reports, 2019.

DOI för Emerging links between cerebrovascular and neurodegenerative diseases-a special role for pericytes

GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients

Hu, Xuchen; Matsumoto, Ken; Jung, Rachel S.; Weston, Thomas A. et al.

Ingår i eLIFE, 2019.

DOI för GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients Ladda ner fulltext (pdf) av GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients

Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single-cell sequencing

van Kuijk, Kim; Kuppe, Christoph; Betsholtz, Christer; Vanlandewijck, Michael et al.

Ingår i Cardiovascular Research, s. 1705-1715, 2019.

DOI för Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single-cell sequencing

Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits

Glicksberg, Benjamin S.; Amadori, Letizia; Akers, Nicholas K.; Sukhavasi, Katyayani et al.

Ingår i BMC Medical Genomics, 2019.

DOI för Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits Ladda ner fulltext (pdf) av Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits

PDGF-B Is Required for Development of the Glymphatic System

Munk, Anne Sofie; Wang, Wei; Bechet, Nicholas Burdon; Eltanahy, Ahmed M. et al.

Ingår i Cell reports, s. 2955-+, 2019.

DOI för PDGF-B Is Required for Development of the Glymphatic System Ladda ner fulltext (pdf) av PDGF-B Is Required for Development of the Glymphatic System

Peri-arterial specification of vascular mural cells from naive mesenchyme requires Notch signaling

Ando, Koji; Wang, Weili; Peng, Di; Chiba, Ayano et al.

Ingår i Development, 2019.

DOI för Peri-arterial specification of vascular mural cells from naive mesenchyme requires Notch signaling

Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFR alpha in Adult Brain

Dang, Thanh Chung; Ishii, Yoko; Nguyen, Van De; Yamamoto, Seiji et al.

Ingår i Cell reports, s. 1073-1089, 2019.

DOI för Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFR alpha in Adult Brain Ladda ner fulltext (pdf) av Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFR alpha in Adult Brain

R3hdml regulates satellite cell proliferation and differentiation

Sakamoto, Kenichi; Furuichi, Yasuro; Yamamoto, Masashi; Takahashi, Megumi et al.

Ingår i EMBO Reports, 2019.

DOI för R3hdml regulates satellite cell proliferation and differentiation

Sprouting and anastomosis in the Drosophila trachea and the vertebrate vasculature: Similarities and differences in cell behaviour

Kotini, Maria Paraskevi; Mäe, Maarja Andaloussi; Belting, Heinz-Georg; Betsholtz, Christer et al.

Ingår i Vascular pharmacology, s. 8-16, 2019.

DOI för Sprouting and anastomosis in the Drosophila trachea and the vertebrate vasculature: Similarities and differences in cell behaviour

A molecular atlas of cell types and zonation in the brain vasculature

Vanlandewijck, Michael; He, Liqun; Mäe, Maarja Andaloussi; Andrae, Johanna et al.

Ingår i Nature, s. 475-480, 2018.

DOI för A molecular atlas of cell types and zonation in the brain vasculature

Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice

Loganathan, Krishnapriya; Salem Said, Ebtisam; Winterrowd, Emily; Orebrand, Martina et al.

Ingår i PLOS ONE, 2018.

DOI för Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice Ladda ner fulltext (pdf) av Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice

Cell-cell signaling in blood vessel development and function

Betsholtz, Christer

Ingår i EMBO Molecular Medicine, 2018.

DOI för Cell-cell signaling in blood vessel development and function Ladda ner fulltext (pdf) av Cell-cell signaling in blood vessel development and function

Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations

Laviña, Bàrbara; Castro, Marco; Niaudet, Colin; Cruys, Bert et al.

Ingår i Development, 2018.

DOI för Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations

Extracellular retention of PDGF-B directs vascular remodeling in mouse hypoxia-induced pulmonary hypertension

Tannenberg, Philip; Chang, Ya-Ting; Muhl, Lars; Laviña, Bàrbara et al.

Ingår i American Journal of Physiology - Lung cellular and Molecular Physiology, s. 1593-1605, 2018.

DOI för Extracellular retention of PDGF-B directs vascular remodeling in mouse hypoxia-induced pulmonary hypertension

Global analysis of A-to-I RNA editing reveals association with common disease variants

Franzen, Oscar; Ermel, Raili; Sukhavasi, Katyayani; Jain, Rajeev et al.

Ingår i PeerJ, 2018.

DOI för Global analysis of A-to-I RNA editing reveals association with common disease variants Ladda ner fulltext (pdf) av Global analysis of A-to-I RNA editing reveals association with common disease variants

Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events

Honkura, Naoki; Richards, Mark; Laviña, Bàrbara; Sainz-Jaspeado, Miguel et al.

Ingår i Nature Communications, 2018.

DOI för Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events Ladda ner fulltext (pdf) av Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events

Inverse correlation between vascular endothelial growth factor back-filtration and capillary filtration pressures

Kuppe, Christoph; Rohlfs, Wilko; Grepl, Martin; Schulte, Kevin et al.

Ingår i Nephrology, Dialysis and Transplantation, s. 1514-1525, 2018.

DOI för Inverse correlation between vascular endothelial growth factor back-filtration and capillary filtration pressures

Multiple roles of lymphatic vessels in peripheral lymph node development

Bovay, Esther; Sabine, Amelie; Prat-Luri, Borja; Kim, Sudong et al.

Ingår i Journal of Experimental Medicine, s. 2760-2777, 2018.

DOI för Multiple roles of lymphatic vessels in peripheral lymph node development

PDGF-A signaling is required for secondary alveolar septation and controls epithelial proliferation in the developing lung

Gouveia, Leonor; Betsholtz, Christer; Andrae, Johanna

Ingår i Development, 2018.

DOI för PDGF-A signaling is required for secondary alveolar septation and controls epithelial proliferation in the developing lung

Pharmacokinetics of Pericyte Involvement in Small-Molecular Drug Transport Across the Blood-Brain Barrier

Mihajlica, Nebojsa; Betsholtz, Christer; Hammarlund-Udenaes, Margareta

Ingår i European Journal of Pharmaceutical Sciences, s. 77-84, 2018.

DOI för Pharmacokinetics of Pericyte Involvement in Small-Molecular Drug Transport Across the Blood-Brain Barrier

Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier

Mäe, Maarja Andaloussi; Li, Tian; Bertuzzi, Giacomo; Raschperger, Elisabeth et al.

Ingår i Scientific Reports, 2018.

DOI för Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier Ladda ner fulltext (pdf) av Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier

Rate of Small-Molecular Drug Transport Across the Blood-Brain Barrier in a Pericyte-Deficient State

Mihajlica, Nebojsa; Betsholtz, Christer; Hammarlund-Udenaes, Margareta

Ingår i European Journal of Pharmaceutical Sciences, s. 182-187, 2018.

DOI för Rate of Small-Molecular Drug Transport Across the Blood-Brain Barrier in a Pericyte-Deficient State

Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

He, Liqun; Vanlandewijck, Michael; Mäe, Maarja Andaloussi; Andrae, Johanna et al.

Ingår i Scientific Data, 2018.

DOI för Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types Ladda ner fulltext (pdf) av Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice

Jung, Bongnam; Arnold, Thomas D.; Raschperger, Elisabeth; Gaengel, Konstantin et al.

Ingår i Journal of Cerebral Blood Flow and Metabolism, s. 456-468, 2018.

DOI för Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice Ladda ner fulltext (pdf) av Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice

Claudin 3-Deficient C57BL/6 Mice Display Intact Brain Barriers

Dias, Mariana; Coisne, Caroline; Baden, Pascale; Lazarevic, Ivana et al.

Ingår i Journal of Vascular Research, s. 63-63, 2017.

Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling

Jin, Yi; Muhl, Lars; Burmakin, Mikhail; Wang, Yixin et al.

Ingår i Nature Cell Biology, s. 639-652, 2017.

DOI för Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling

Expression analysis of platelet-derived growth factor receptor alpha and its ligands in the developing mouse lung

Gouveia, Leonor; Betsholtz, Christer; Andrae, Johanna

Ingår i Physiological Reports, 2017.

DOI för Expression analysis of platelet-derived growth factor receptor alpha and its ligands in the developing mouse lung Ladda ner fulltext (pdf) av Expression analysis of platelet-derived growth factor receptor alpha and its ligands in the developing mouse lung

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

Jones, Gregory T.; Tromp, Gerard; Kuivaniemi, Helena; Gretarsdottir, Solveig et al.

Ingår i Circulation Research, s. 341-+, 2017.

DOI för Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci Ladda ner fulltext (pdf) av Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

PDGFR alpha signaling is required for alveolar development in the mouse lung

Andrae, Johanna; Betsholtz, Christer; Gouveia, Maria Leonor Seguardo

Ingår i Mechanisms of Development, s. S147-S147, 2017.

DOI för PDGFR alpha signaling is required for alveolar development in the mouse lung

Pericytes promote the generation of oligodendrocytes during remyelination

Guzman, A.; Lange, S.; Silva, M. E.; Gonzalez, G. A. et al.

Ingår i Glia, s. E541-E542, 2017.

DOI för Pericytes promote the generation of oligodendrocytes during remyelination

Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination

De La Fuente, Alerie Guzman; Lange, Simona; Silva, Maria Elena; Gonzalez, Ginez A. et al.

Ingår i Cell reports, s. 1755-1764, 2017.

DOI för Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination

Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity

Wang, Yixin; Jin, Yi; Mäe, Maarja Andaloussi; Zhang, Yang et al.

Ingår i Development, s. 3590-3601, 2017.

DOI för Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

Webb, Thomas R.; Erdmann, Jeanette; Stirrups, Kathleen E.; Stitziel, Nathan O. et al.

Ingår i Journal of the American College of Cardiology, s. 823-836, 2017.

DOI för Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease Ladda ner fulltext (pdf) av Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

The role of microglia in microvascular calcification in the brain

Keller, A.; Zarb, Y.; Johannson, B.; Betsholtz, Christer et al.

Ingår i Glia, s. E509-E509, 2017.

DOI för The role of microglia in microvascular calcification in the brain

Transcriptomic and Proteomic Profiling Provides Insight into Mesangial Cell Function in IgA Nephropathy

Liu, Peidi; Lassen, Emelie; Nair, Viji; Berthier, Celine C. et al.

Ingår i Journal of the American Society of Nephrology, s. 2961-2972, 2017.

DOI för Transcriptomic and Proteomic Profiling Provides Insight into Mesangial Cell Function in IgA Nephropathy

A novel podocyte gene, semaphorin 3G, protects glomerular podocyte from lipopolysaccharide-induced inflammation

Ishibashi, Ryoichi; Takemoto, Minoru; Akimoto, Yoshihiro; Ishikawa, Takahiro et al.

Ingår i Scientific Reports, 2016.

DOI för A novel podocyte gene, semaphorin 3G, protects glomerular podocyte from lipopolysaccharide-induced inflammation Ladda ner fulltext (pdf) av A novel podocyte gene, semaphorin 3G, protects glomerular podocyte from lipopolysaccharide-induced inflammation

A role for PDGF-C/PDGFR alpha signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex

Andrae, Johanna; Gouveia, Leonor; Gallini, Radiosa; He, Liqun et al.

Ingår i BIOLOGY OPEN, s. 461-474, 2016.

DOI för A role for PDGF-C/PDGFR alpha signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex Ladda ner fulltext (pdf) av A role for PDGF-C/PDGFR alpha signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex

Age-dependent modulation of vascular niches for haematopoietic stem cells

Kusumbe, Anjali P.; Ramasamy, Saravana K.; Itkin, Tomer; Mae, Maarja Andaloussi et al.

Ingår i Nature, s. 380-+, 2016.

DOI för Age-dependent modulation of vascular niches for haematopoietic stem cells

An Endothelial Gene Signature Score Predicts Poor Outcome in Patients with Endocrine-Treated, Low Genomic Grade Breast Tumors

Tobin, Nicholas P.; Wennmalm, Kristian; Lindstrom, Linda S.; Foukakis, Theodoros et al.

Ingår i Clinical Cancer Research, s. 2417-2426, 2016.

DOI för An Endothelial Gene Signature Score Predicts Poor Outcome in Patients with Endocrine-Treated, Low Genomic Grade Breast Tumors

Analysis of the brain mural cell transcriptome

He, Liqun; Vanlandewijck, Michael; Raschperger, Elisabeth; Mae, Maarja Andaloussi et al.

Ingår i Scientific Reports, 2016.

DOI för Analysis of the brain mural cell transcriptome Ladda ner fulltext (pdf) av Analysis of the brain mural cell transcriptome

Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci

Miller, Clint L.; Pjanic, Milos; Wang, Ting; Nguyen, Trieu et al.

Ingår i Nature Communications, 2016.

DOI för Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci Ladda ner fulltext (pdf) av Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci

Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart

Gallini, Radiosa; Huusko, Jenni; Yla-Herttuala, Seppo; Betsholtz, Christer et al.

Ingår i PLOS ONE, 2016.

DOI för Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart Ladda ner fulltext (pdf) av Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart

Lack Of Pdgf-B Retention Ameliorates Hypoxia-Induced Pulmonary Hypertension

Tannenberg, P.; Folestad, E.; Chang, Y. -T; Gladh, H. et al.

Ingår i American Journal of Respiratory and Critical Care Medicine, 2016.

Mice Lacking Platelet-Derived Growth Factor D Display a Mild Vascular Phenotype

Gladh, Hanna; Folestad, Erika Bergsten; Muhl, Lars; Ehnman, Monika et al.

Ingår i PLOS ONE, 2016.

DOI för Mice Lacking Platelet-Derived Growth Factor D Display a Mild Vascular Phenotype Ladda ner fulltext (pdf) av Mice Lacking Platelet-Derived Growth Factor D Display a Mild Vascular Phenotype

Oligodendrocytes follow blood vessel trails in the brain Brain microvasculature is a scaffold for neuroglial migration

Dejana, Elisabetta; Betsholtz, Christer

Ingår i Science, s. 341-342, 2016.

DOI för Oligodendrocytes follow blood vessel trails in the brain Brain microvasculature is a scaffold for neuroglial migration

PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice

Gallini, Radiosa; Lindblom, Per; Bondjers, Cecilia; Betsholtz, Christer et al.

Ingår i Experimental Cell Research, s. 282-290, 2016.

DOI för PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice Ladda ner fulltext (pdf) av PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice

Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis

Rivera-Gonzalez, Guillermo C.; Shook, Brett A.; Andrae, Johanna; Holtrup, Brandon et al.

Ingår i Cell Stem Cell, s. 738-751, 2016.

DOI för Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis

Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier

Villasenor, Roberto; Ozmen, Laurence; Messaddeq, Nadia; Gruninger, Fiona et al.

Ingår i Scientific Reports, 2016.

DOI för Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier Ladda ner fulltext (pdf) av Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier

Transcriptional control of endothelial energy

Betsholtz, Christer

Ingår i Nature, s. 160-161, 2016.

DOI för Transcriptional control of endothelial energy

VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread

Li, Xiujuan; Padhan, Narendra; Sjöström, Elisabet O.; Roche, Francis P. et al.

Ingår i Nature Communications, 2016.

DOI för VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread Ladda ner fulltext (pdf) av VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

Zeisel, Amit; Munoz-Manchado, Ana B.; Codeluppi, Simone; Lonnerberg, Peter et al.

Ingår i Science, s. 1138-1142, 2015.

DOI för Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels

Stanczuk, Lukas; Martinez-Corral, Ines; Ulvmar, Maria H.; Zhang, Yang et al.

Ingår i Cell reports, s. 1708-1721, 2015.

DOI för cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels Ladda ner fulltext (pdf) av cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels

Establishment and Dysfunction of the Blood-Brain Barrier

Zhao, Zhen; Nelson, Amy R.; Betsholtz, Christer; Zlokovic, Berislav V.

Ingår i Cell, s. 1064-1078, 2015.

DOI för Establishment and Dysfunction of the Blood-Brain Barrier

Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification

Vanlandewijck, Michael; Lebouvier, Thibaud; Mae, Maarja Andaloussi; Nahar, Khayrun et al.

Ingår i PLOS ONE, 2015.

DOI för Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification Ladda ner fulltext (pdf) av Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification