Publications in DiVA – Magnus Essand
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Complementarity-determining region clustering may cause CAR-T cell dysfunction
Part of Nature Communications, 2023.
DOI for Complementarity-determining region clustering may cause CAR-T cell dysfunction Download full text (pdf) of Complementarity-determining region clustering may cause CAR-T cell dysfunction
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Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer
Part of Frontiers in Immunology, 2023.
DOI for Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer Download full text (pdf) of Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer
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Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
Part of Cancer Cell, p. 1134-1151, 2023.
DOI for Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma Download full text (pdf) of Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
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CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers
Part of Nature Biomedical Engineering, p. 830-841, 2022.
DOI for CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers Download full text (pdf) of CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers
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CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation
Part of Molecular Therapy Nucleic Acids, p. 450-461, 2022.
DOI for CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation Download full text (pdf) of CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation
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Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response
Part of Oncoimmunology, 2022.
DOI for Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response Download full text (pdf) of Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response
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Ixovex-1, a novel oncolytic E1B-mutated adenovirus
Part of Cancer Gene Therapy, p. 1628-1635, 2022.
DOI for Ixovex-1, a novel oncolytic E1B-mutated adenovirus Download full text (pdf) of Ixovex-1, a novel oncolytic E1B-mutated adenovirus
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Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy
Part of Cancer Imaging, 2022.
DOI for Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy Download full text (pdf) of Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy
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ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
Part of Frontiers in Immunology, 2022.
DOI for ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression Download full text (pdf) of ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
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Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma
Part of Nature Communications, 2021.
DOI for Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma Download full text (pdf) of Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma
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Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy
Part of Nanomaterials, 2021.
DOI for Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy Download full text (pdf) of Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy
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IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma
Part of MOLECULAR THERAPY-ONCOLYTICS, p. 37-46, 2021.
DOI for IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma Download full text (pdf) of IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma
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Perivascular macrophages regulate blood flow following tissue damage
Part of Circulation Research, p. 1694-1707, 2021.
DOI for Perivascular macrophages regulate blood flow following tissue damage
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Tertiary Lymphoid Structures in the Central Nervous System: Implications for Glioblastoma
Part of Frontiers in Immunology, 2021.
DOI for Tertiary Lymphoid Structures in the Central Nervous System: Implications for Glioblastoma Download full text (pdf) of Tertiary Lymphoid Structures in the Central Nervous System: Implications for Glioblastoma
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Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain
Part of Journal of Neuroinflammation, 2020.
DOI for Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain Download full text (pdf) of Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain
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Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer
Part of Cell Death and Disease, 2020.
DOI for Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer Download full text (pdf) of Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer
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TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment
Part of Haematologica, p. 1306-1316, 2020.
DOI for TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment Download full text (pdf) of TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment
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Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy
Part of Oncoimmunology, 2020.
DOI for Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy Download full text (pdf) of Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy
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Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
Part of Cell Stem Cell, p. 855-870, 2019.
DOI for Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy Download full text (pdf) of Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
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LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients
Part of Journal of Pathology, p. 228-240, 2019.
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A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia
Part of Clinical Cancer Research, p. 6185-6194, 2018.
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Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models
Part of Oncoimmunology, 2018.
DOI for Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models Download full text (pdf) of Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models
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CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis
Part of Journal of Clinical Investigation, p. 3280-3297, 2018.
DOI for CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis Download full text (pdf) of CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis
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Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity
Part of Molecular Cancer Therapeutics, p. 1961-1972, 2018.
DOI for Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity Download full text (pdf) of Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity
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Modifying melanoma immune microenvironment by heterologous prime-boost vaccination with adenovirus and Modified Vaccinia Ankara virus vectors
Part of Experimental dermatology, p. E54-E55, 2018.
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Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth
Part of Proceedings of the National Academy of Sciences of the United States of America, p. E3808-E3816, 2018.
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Perivascular macrophages regulate blood flow following tissue damage
Part of European Journal of Clinical Investigation, p. 44-45, 2018.
DOI for Perivascular macrophages regulate blood flow following tissue damage
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Adenovirus, Semliki Forest virus and vaccinia virus-induced immunogenic cell death augments oncolytic virus immunotherapy
Part of Scandinavian Journal of Immunology, p. 341-341, 2017.
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CAR T-Cells with Induced Secretion of Helicobacter Pylori Neutrophil-Activating Protein (HP-NAP) Yields Improved Anti-Tumor Activity and Reduced Immunosuppression
Part of Molecular Therapy, p. 288-288, 2017.
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Immunological biomarkers correlate to survival in CAR19-treated patients
Part of Scandinavian Journal of Immunology, p. 337-337, 2017.
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PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c
Part of Nucleic Acids Research, p. 2408-2422, 2017.
DOI for PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c
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Preclinical Evaluation of AdVince, an Oncolytic Adenovirus Adapted for Treatment of Liver Metastases from Neuroendocrine Cancer
Part of Neuroendocrinology, p. 54-66, 2017.
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Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus
Part of Clinical Cancer Research, p. 1519-1530, 2017.
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The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells
Part of Seminars in Cancer Biology, p. 23-35, 2017.
DOI for The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells Download full text (pdf) of The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells
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A Clinical Trial Using Third Generation CD19 Targeting CAR T Cells for Relapsed Lymphoma and Leukemia
Part of Molecular Therapy, p. S295-S296, 2016.
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Avidity characterization of genetically engineered T-cells with novel and established approaches
Part of BMC Immunology, 2016.
DOI for Avidity characterization of genetically engineered T-cells with novel and established approaches Download full text (pdf) of Avidity characterization of genetically engineered T-cells with novel and established approaches
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CD19-targeting third generation CAR T cells for relapsed and refractory lymphoma and leukemia: report from the Swedish phase Ulla trial
Part of CANCER IMMUNOLOGY RESEARCH, 2016.
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Heparanase Promotes Glioma Progression and is Inversely Correlated with Patient Survival.
Part of Molecular Cancer Research, p. 1243-1253, 2016.
DOI for Heparanase Promotes Glioma Progression and is Inversely Correlated with Patient Survival.
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miR-196a Is Specifically Regulated in FDG-PET Positive and Negative Small Intestinal Neuroendocrine Tumor Patients at Late Stage of Disease
Part of Neuroendocrinology, p. 115-115, 2016.
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Prospects to improve chimeric antigen receptor T-cell therapy for solid tumors
Part of Immunotherapy, p. 1355-1361, 2016.
DOI for Prospects to improve chimeric antigen receptor T-cell therapy for solid tumors
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Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer
Part of EMBO Molecular Medicine, p. 702-711, 2016.
DOI for Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer Download full text (pdf) of Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer
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Chimeric Antigen Receptor-Engineered T Cells for the Treatment of Metastatic Prostate Cancer
Part of BioDrugs, p. 75-89, 2015.
DOI for Chimeric Antigen Receptor-Engineered T Cells for the Treatment of Metastatic Prostate Cancer Download full text (pdf) of Chimeric Antigen Receptor-Engineered T Cells for the Treatment of Metastatic Prostate Cancer
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Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival
Part of Cancer Research, p. 4504-4516, 2015.
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Immunological shielding by induced recruitment of regulatory T lymphocytes delays rejection of islets transplanted to muscle
Part of Cell Transplantation, p. 263-276, 2015.
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Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle
Part of Cell Transplantation, p. 263-276, 2015.
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Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model
Part of Regenerative Medicine Research, 2015.
DOI for Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model Download full text (pdf) of Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model
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Other Novel Therapies: Biomarkers, microRNAs and microRNA Inhibitors, DNA Methylation, Epigenetics, Immunotherapy and Virotherapy
Part of Neuroendocrine Tumors, p. 248-262, 2015.
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A Hexon and Fiber-modified Adenovirus Expressing CD40L Improves the Antigen Presentation Capacity of Dendritic Cells
Part of Journal of immunotherapy (1997), p. 155-162, 2014.
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Adenovirus Encoded Helicobacter pylori Neutrophil Activating Protein Promotes Maturation of DCs with Th-1 Polarization, Improved Antigen Presentation and Migration
Part of Molecular Therapy, p. S242-S243, 2014.
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Allogeneic lymphocyte-licensed DCs expand T cells withimproved antitumor activity and resistance to oxidative stress andimmunosuppressive factors
Part of Molecular Therapy Methods & Clinical Development, 2014.
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Allogeneic Lymphocyte-Licensed DCs Expand TCR/CAR-Engineered T Cells, Which Are Insensitive To Oxidative Stress and Immunosuppressive Factors
Part of Molecular Therapy, p. S62-S62, 2014.
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Engineering Regulatory Cells With a T Cell Receptor for Controlled Activation
Part of Molecular Therapy, p. S180-S180, 2014.
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Histidine-Rich Glycoprotein (HRG): A Novel Gene-Therapy Effector for the Treatment of Cancer
Part of Molecular Therapy, p. S243-S244, 2014.
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Long-term episomal gene transfer for safe engineering of T-cells for adoptive cell therapy of cancer
Part of Human Gene Therapy, p. A50-A50, 2014.
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Preclinical Safety Assessment of Ad[I/PPT-E1A], a Novel Oncolytic Adenovirus for Prostate Cancer
Part of Human Gene Therapy Clinical Development, p. 7-15, 2014.
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Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice
Part of BMC Cancer, p. 30-, 2014.
DOI for Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice Download full text (pdf) of Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice
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Vector-Encoded Helicobacter pylori Neutrophil-Activating Protein Promotes Maturation of Dendritic Cells with Th1 Polarization and Improved Migration
Part of Journal of Immunology, p. 2287-2296, 2014.
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Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures
Part of PLOS ONE, p. e54952-, 2013.
DOI for Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures Download full text (pdf) of Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures
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An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors
Part of Molecular Therapy, p. 2008-2018, 2013.
DOI for An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors Download full text (pdf) of An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors
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Genetically engineered T cells for the treatment of cancer
Part of Journal of Internal Medicine, p. 166-181, 2013.
DOI for Genetically engineered T cells for the treatment of cancer
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Histidine-Rich Glycoprotein (HRG): A Novel Gene-Therapy Effector for the Treatment of Cancer
Part of Molecular Therapy, p. S241-S241, 2013.
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Islet Engraftment and Revascularization in Clinical and Experimental Transplantation
Part of Cell Transplantation, p. 243-251, 2013.
DOI for Islet Engraftment and Revascularization in Clinical and Experimental Transplantation
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Strategic recruitment of proangiogenic leukocytes to the ischemic hindlimb increases functional tissue perfusion
Part of European Journal of Clinical Investigation, p. 27-27, 2013.
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Tat‐PTD‐modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy
Part of Human Gene Therapy, p. 766-775, 2013.
DOI for Tat‐PTD‐modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy Download full text (pdf) of Tat‐PTD‐modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy
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Virotherapy of Neuroendocrine Tumors
Part of Neuroendocrinology, p. 26-34, 2013.
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Age-related somatic structural changes in the nuclear genome of human blood cells
Part of American Journal of Human Genetics, p. 217-228, 2012.
DOI for Age-related somatic structural changes in the nuclear genome of human blood cells
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CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery
Part of Journal of Neuroinflammation, p. 112-, 2012.
DOI for CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery Download full text (pdf) of CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery
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T cells engineered with a T cell receptor against the prostate antigen TARP specifically kill HLA-A2+ prostate and breast cancer cells
Part of Proceedings of the National Academy of Sciences of the United States of America, p. 15877-15881, 2012.
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Adenovirus with Hexon Tat-Protein Transduction Domain Modification Exhibits Increased Therapeutic Effect in Experimental Neuroblastoma and Neuroendocrine Tumors
Part of Journal of Virology, p. 13114-13123, 2011.
DOI for Adenovirus with Hexon Tat-Protein Transduction Domain Modification Exhibits Increased Therapeutic Effect in Experimental Neuroblastoma and Neuroendocrine Tumors Download full text (pdf) of Adenovirus with Hexon Tat-Protein Transduction Domain Modification Exhibits Increased Therapeutic Effect in Experimental Neuroblastoma and Neuroendocrine Tumors
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Oncolytic Viruses for the Treatment of Neuroendocrine Tumors
Part of Hormone and Metabolic Research, p. 877-883, 2011.
DOI for Oncolytic Viruses for the Treatment of Neuroendocrine Tumors
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Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors
Part of Cancer Research, p. 1805-1815, 2011.
DOI for Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors
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An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood
Part of Gene Therapy, p. 752-762, 2010.
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Clinical Adenoviral Gene Therapy for Prostate Cancer
Part of Human Gene Therapy, p. 807-813, 2010.
DOI for Clinical Adenoviral Gene Therapy for Prostate Cancer
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Generation of antigen-specific cytolytic T cells for prostate cancer therapy
Part of Human Gene Therapy, p. 1422-1422, 2010.
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High frequency of prostate antigen-directed T cells in cancer patients compared to healthy age-matched individuals
Part of The Prostate, p. 70-81, 2009.
DOI for High frequency of prostate antigen-directed T cells in cancer patients compared to healthy age-matched individuals Download full text (pdf) of High frequency of prostate antigen-directed T cells in cancer patients compared to healthy age-matched individuals
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Midgut carcinoid patients display increased numbers of regulatory T cells in peripheral blood with infiltration into tumor tissue
Part of Acta Oncologica, p. 391-400, 2009.
DOI for Midgut carcinoid patients display increased numbers of regulatory T cells in peripheral blood with infiltration into tumor tissue Download full text (pdf) of Midgut carcinoid patients display increased numbers of regulatory T cells in peripheral blood with infiltration into tumor tissue
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CD8(+) T cells against multiple tumor-associated antigens in peripheral blood of midgut carcinoid patients
Part of Cancer Immunology and Immunotherapy, p. 399-409, 2008.
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CpG oligonucleotides demonstrate increased therapeutic efficacy compared to BCG in an aggressive orthotopic bladder cancer model
Part of Journal of immunotherapy (1997), p. 34-42, 2008.
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CpG Therapy is Superior to BCG in an Orthotopic Bladder Cancer Model and Generates CD4+ T-cell Immunity
Part of Journal of immunotherapy (1997), p. 34-42, 2008.
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Increased therapeutic efficacy of the prostate-specific oncolytic adenovirus Ad[I/PPT-E1A] by reduction of the insulator size and introduction of the full-length E3 region
Part of Cancer Gene Therapy, p. 203-213, 2008.
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Strategic use of an adenoviral vector for rapid and efficient ex vivo-generation of cytomegalovirus pp65-reactive cytolytic and helper T cells
Part of British Journal of Haematology, p. 188-199, 2008.
DOI for Strategic use of an adenoviral vector for rapid and efficient ex vivo-generation of cytomegalovirus pp65-reactive cytolytic and helper T cells Download full text (pdf) of Strategic use of an adenoviral vector for rapid and efficient ex vivo-generation of cytomegalovirus pp65-reactive cytolytic and helper T cells