Publications in DiVA Mats Hellström

Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC

Hasselblatt, Martin; Thomas, Christian; Federico, Aniello; Bens, Susanne et al.

Part of Neuropathology and Applied Neurobiology, 2022.

DOI for Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC Download full text (pdf) of Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC

Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma

Simonds, Erin F.; Lu, Edbert D.; Badillo, Oscar; Karimi, Shokoufeh et al.

Part of Journal for ImmunoTherapy of Cancer, 2021.

DOI for Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma Download full text (pdf) of Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma

Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis

Nitzsche, Anja; Pietilä, Riikka; Love, Dominic T.; Testini, Chiara et al.

Part of EMBO Reports, 2021.

DOI for Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis Download full text (pdf) of Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis

Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2

Testini, Chiara; Smith, Ross O.; Jin, Yi; Martinsson, Pernilla et al.

Part of EMBO Reports, 2019.

DOI for Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2 Download full text (pdf) of Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2

Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells

Kundu, Snehangshu; Ali, Muhammad Akhtar; Handin, Niklas; Padhan, Narendra et al.

Part of Genome Medicine, 2018.

DOI for Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells

Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema

Egaña, Isabel; Kaito, Hiroshi; Nitzsche, Anja; Becker, Lore et al.

Part of Scientific Reports, 2017.

DOI for Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema Download full text (pdf) of Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema

Somatic PRDM2 c.4467delA mutations in colorectal cancers control histone methylation and tumor growth

Pandzic, Tatjana; Rendo, Verónica; Lim, Jinyeong; Larsson, Chatarina et al.

Part of OncoTarget, p. 98646-98659, 2017.

DOI for Somatic PRDM2 c.4467delA mutations in colorectal cancers control histone methylation and tumor growth

Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia

Pandzic, Tatjana; Larsson, Jimmy; He, Liqun; Kundu, Snehangshu et al.

Part of Clinical Cancer Research, p. 6217-6227, 2016.

DOI for Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia

Endothelial cell spheroids as a versatile tool to study angiogenesis in vitro

Heiss, Maximilian; Hellstrom, Mats; Kalen, Mattias; May, Tobias et al.

Part of The FASEB Journal, p. 3076-3084, 2015.

DOI for Endothelial cell spheroids as a versatile tool to study angiogenesis in vitro

Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia

Mansouri, Larry; Sutton, Lesley-Ann; Ljungström, Viktor; Bondza, Sina et al.

Part of Journal of Experimental Medicine, p. 833-843, 2015.

DOI for Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia Download full text (pdf) of Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia

Improving Pancreatic Islet Engraftment after Islet Transplantation through Administration of Gamma-Secretase Inhibitor DAPT

Hjelmqvist, Daisy; Hellström, Mats; Lau, Joey

Part of Journal of endocrinology and diabetes mellitus, p. 65-69, 2014.

DOI for Improving Pancreatic Islet Engraftment after Islet Transplantation through Administration of Gamma-Secretase Inhibitor DAPT Download full text (pdf) of Improving Pancreatic Islet Engraftment after Islet Transplantation through Administration of Gamma-Secretase Inhibitor DAPT

Recurrent Mutations within the Nfkbie gene: A Novel Mechanism for NF-kappa B Deregulation in Aggressive Chronic Lymphocytic Leukemia

Mansouri, Larry; Sutton, Lesley-Ann; Ljungström, Viktor; Bondza, Sina et al.

Part of Blood, 2014.

Notch as a hub for signaling in angiogenesis

Benedito, Rui; Hellström, Mats

Part of Experimental Cell Research, p. 1281-1288, 2013.

DOI for Notch as a hub for signaling in angiogenesis

Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development

Wallgard, Elisabet; Nitzsche, Anja; Larsson, Jimmy; Guo, Xiaoyuan et al.

Part of Developmental Dynamics, p. 770-786, 2012.

DOI for Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development

The Sphingosine-1-Phosphate Receptor S1PR1 Restricts Sprouting Angiogenesis by Regulating the Interplay between VE-Cadherin and VEGFR2

Gaengel, Konstantin; Niaudet, Colin; Hagikura, Kazuhiro; Siemsen, Barbara Lavina et al.

Part of Developmental Cell, p. 587-599, 2012.

DOI for The Sphingosine-1-Phosphate Receptor S1PR1 Restricts Sprouting Angiogenesis by Regulating the Interplay between VE-Cadherin and VEGFR2

Gamma-Secretase Inhibitor Treatment Promotes VEGF-A-Driven Blood Vessel Growth and Vascular Leakage but Disrupts Neovascular Perfusion

Kalén, Mattias; Heikura, Tommi; Karvinen, Henna; Nitzsche, Anja et al.

Part of PLOS ONE, p. e18709-, 2011.

DOI for Gamma-Secretase Inhibitor Treatment Promotes VEGF-A-Driven Blood Vessel Growth and Vascular Leakage but Disrupts Neovascular Perfusion

Therapeutic efficacy of a DNA vaccine targeting the endothelial tip cell antigen delta-like ligand 4 in mammary carcinoma.

Haller, B K; Bråve, A; Wallgard, Elisabet; Roswall, P et al.

Part of Oncogene, p. 4276-86, 2010.

DOI for Therapeutic efficacy of a DNA vaccine targeting the endothelial tip cell antigen delta-like ligand 4 in mammary carcinoma.

Combination of reverse and chemical genetic screens reveals angiogenesis inhibitors and targets.

Kalén, Mattias; Wallgard, Elisabet; Asker, Noomi; Nasevicius, Aidas et al.

Part of Chemistry and Biology, p. 432-41, 2009.

DOI for Combination of reverse and chemical genetic screens reveals angiogenesis inhibitors and targets.

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation.

Tammela, Tuomas; Zarkada, Georgia; Wallgard, Elisabet; Murtomäki, Aino et al.

Part of Nature, p. 656-60, 2008.

DOI for Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation.

Identification of a core set of 58 gene transcripts with broad and specific expression in the microvasculature.

Wallgard, Elisabet; Larsson, Erik; He, Liqun; Hellström, Mats et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 1469-76, 2008.

DOI for Identification of a core set of 58 gene transcripts with broad and specific expression in the microvasculature.

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.

Hellström, Mats; Phng, Li-Kun; Hofmann, Jennifer J; Wallgard, Elisabet et al.

Part of Nature, p. 776-80, 2007.

DOI for Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.

Paladin (Pald1) regulates endothelial sprouting, VE-cadherin junction stability and vascular permeability

Nitzsche, Anja; Testini, Chiara; Ekvärn, Elisabet; Larsson, Jimmy et al.