Publications in DiVA – Olle Korsgren

[¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44

Cheung, Pierre; Amin, Mohammad A.; Zhang, Bo; Lechi, Francesco et al.

Part of Pharmaceutics, 2023.

DOI for [¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44 Download full text (pdf) of [¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44

A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats

Tegehall, Angelica; Ingvast, Sofie; Melhus, Åsa; Skog, Oskar et al.

Part of Acta Diabetologica, p. 1011-1018, 2022.

DOI for A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats Download full text (pdf) of A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats

Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets

Golec, Ewelina; Ekstrom, Alexander; Noga, Maciej; Omar-Hmeadi, Muhmmad et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2022.

DOI for Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets Download full text (pdf) of Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets

Islet Gene View-a tool to facilitate islet research

Asplund, Olof; Storm, Petter; Chandra, Vikash; Hatem, Gad et al.

Part of Life Science Alliance, 2022.

DOI for Islet Gene View-a tool to facilitate islet research Download full text (pdf) of Islet Gene View-a tool to facilitate islet research

Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

Diamanti, Klev; Cavalli, Marco; Pereira, Maria J.; Pan, Gang et al.

Part of Cell Reports Medicine, 2022.

DOI for Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues Download full text (pdf) of Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

PET imaging of neutrophil elastase with ¹¹C-GW457427 in Acute Respiratory Distress Syndrome in pigs

Puuvuori, Emmi; Chiodaroli, Elena; Estrada, Sergio; Cheung, Pierre et al.

Part of Journal of Nuclear Medicine, 2022.

DOI for PET imaging of neutrophil elastase with ¹¹C-GW457427 in Acute Respiratory Distress Syndrome in pigs

PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE

Puuvuori, Emmi; Liggieri, Francesco; Velikyan, Irina; Chiodaroli, Elena et al.

Part of EJNMMI Research, 2022.

DOI for PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE Download full text (pdf) of PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE

3D imaging of human organs with micrometer resolution-applied to the endocrine pancreas

Hahn, Max; Nord, Christoffer; Eriksson, Maria; Morini, Federico et al.

Part of Communications Biology, 2021.

DOI for 3D imaging of human organs with micrometer resolution-applied to the endocrine pancreas Download full text (pdf) of 3D imaging of human organs with micrometer resolution-applied to the endocrine pancreas

Adenoviral CD40 Ligand Immunotherapy in 32 Canine Malignant Melanomas-Long-Term Follow Up

Saellstrom, Sara; Sadeghi, Arian; Eriksson, Emma; Segall, Thomas et al.

Part of Frontiers in Veterinary Science, 2021.

DOI for Adenoviral CD40 Ligand Immunotherapy in 32 Canine Malignant Melanomas-Long-Term Follow Up Download full text (pdf) of Adenoviral CD40 Ligand Immunotherapy in 32 Canine Malignant Melanomas-Long-Term Follow Up

Autologous regulatory T cells in clinical intraportal allogenic pancreatic islet transplantation

Bergström, Marcus; Yao, Ming; Müller, Malin; Korsgren, Olle et al.

Part of Transplant International, p. 2816-2823, 2021.

DOI for Autologous regulatory T cells in clinical intraportal allogenic pancreatic islet transplantation Download full text (pdf) of Autologous regulatory T cells in clinical intraportal allogenic pancreatic islet transplantation

Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study

Oikarinen, Sami; Krogvold, Lars; Edwin, Bjorn; Buanes, Trond et al.

Part of Diabetologia, p. 2491-2501, 2021.

DOI for Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study Download full text (pdf) of Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study

Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69

Persson, Jonas; Puuvuori, Emmi; Zhang, Bo; Velikyan, Irina et al.

Part of Scientific Reports, 2021.

DOI for Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69 Download full text (pdf) of Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69

Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes

Granlund, Louise; Hedin, Anders; Wahlhuetter, Miriam; Seiron, Peter et al.

Part of BMJ Open Diabetes Research & Care, 2021.

DOI for Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes Download full text (pdf) of Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes

Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes

Espes, Daniel; Carlsson, Per-Ola; Selvaraju, Ram Kumar; Rosestedt, Maria et al.

Part of Diabetes, p. 966-975, 2021.

DOI for Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes

Perivascular macrophages regulate blood flow following tissue damage

Vågesjö, Evelina; Parv, Kristel; Ahl, David; Seignez, Cedric et al.

Part of Circulation Research, p. 1694-1707, 2021.

DOI for Perivascular macrophages regulate blood flow following tissue damage

PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Cheung, Pierre; Zhang, Bo; Puuvuori, Emmi; Estrada, Sergio et al.

Part of Biomedicines, 2021.

DOI for PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs Download full text (pdf) of PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Phase 3 trial of human islet-after-kidney transplantation in type 1 diabetes

Markmann, James F.; Rickels, Michael R.; Eggerman, Thomas L.; Bridges, Nancy D. et al.

Part of American Journal of Transplantation, p. 1477-1492, 2021.

DOI for Phase 3 trial of human islet-after-kidney transplantation in type 1 diabetes

Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1

Rosestedt, Maria; Velikyan, Irina; Rosenström, Ulrika; Estrada, Sergio et al.

Part of Nuclear Medicine and Biology, p. 54-62, 2021.

DOI for Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1 Download full text (pdf) of Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1

Transcriptional analysis of islets of Langerhans from organ donors of different ages

Seiron, Peter; Stenwall, Per-Anton; Hedin, Anders; Granlund, Louise et al.

Part of PLOS ONE, 2021.

DOI for Transcriptional analysis of islets of Langerhans from organ donors of different ages

US food and drug administration (FDA) panel endorses islet cell treatment for type 1 diabetes: A pyrrhic victory?

Piemonti, Lorenzo; Andres, Axel; Casey, John; de Koning, Eelco et al.

Part of Transplant International, p. 1182-1186, 2021.

DOI for US food and drug administration (FDA) panel endorses islet cell treatment for type 1 diabetes: A pyrrhic victory?

Heterogeneity of Human Pancreatic Islet Isolation Around Europe: Results of a Survey Study

Nano, Rita; Kerr-Conte, Julie A.; Scholz, Hanne; Engelse, Marten et al.

Part of Transplantation, p. 190-196, 2020.

DOI for Heterogeneity of Human Pancreatic Islet Isolation Around Europe: Results of a Survey Study

Inhibition of the prostaglandin D₂-GPR44/DP2 axis improves human islet survival and function

Abadpour, Shadab; Tyrberg, Bjorn; Schive, Simen W.; Huldt, Charlotte Wennberg et al.

Part of Diabetologia, p. 1355-1367, 2020.

DOI for Inhibition of the prostaglandin D₂-GPR44/DP2 axis improves human islet survival and function Download full text (pdf) of Inhibition of the prostaglandin D₂-GPR44/DP2 axis improves human islet survival and function

Mesoscopic 3D imaging of pancreatic cancer and Langerhans islets based on tissue autofluorescence

Hahn, Max; Nord, Christoffer; Franklin, Oskar; Alanentalo, Tomas et al.

Part of Scientific Reports, 2020.

DOI for Mesoscopic 3D imaging of pancreatic cancer and Langerhans islets based on tissue autofluorescence Download full text (pdf) of Mesoscopic 3D imaging of pancreatic cancer and Langerhans islets based on tissue autofluorescence

Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells

Neiman, Daniel; Gillis, David; Piyanzin, Sheina; Cohen, Daniel et al.

Part of JCI Insight, 2020.

DOI for Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells

On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes

Skog, Oskar; Korsgren, Olle

Part of Acta Diabetologica, p. 503-511, 2020.

DOI for On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes Download full text (pdf) of On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes

Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Type 1 Diabetes

Maffi, Paola; Lundgren, Torbjorn; Tufveson, Gunnar; Rafael, Ehab et al.

Part of Diabetes Care, p. 710-718, 2020.

DOI for Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Type 1 Diabetes

The role of vitamin D in the aetiology of type 1 diabetes

Korsgren, Olle

Part of Diabetologia, p. 1279-1280, 2020.

DOI for The role of vitamin D in the aetiology of type 1 diabetes

Transcriptional profiles of human islet and exocrine endothelial cells in subjects with or without impaired glucose metabolism

Jonsson, Alexander; Hedin, Anders; Müller, Malin; Skog, Oskar et al.

Part of Scientific Reports, 2020.

DOI for Transcriptional profiles of human islet and exocrine endothelial cells in subjects with or without impaired glucose metabolism Download full text (pdf) of Transcriptional profiles of human islet and exocrine endothelial cells in subjects with or without impaired glucose metabolism

A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development.

Helker, Christian S M; Mullapudi, Sri-Teja; Mueller, Laura M; Preussner, Jens et al.

Part of Development, 2019.

DOI for A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development.

Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced

Seiron, Peter; Wiberg, Anna; Kuric, Enida; Krogvold, Lars et al.

Part of The journal of pathology. Clinical research, p. 248-255, 2019.

DOI for Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced Download full text (pdf) of Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced

Characterization of host defense molecules in the human pancreas

Stenwall, Anton; Ingvast, Sofie; Skog, Oskar; Korsgren, Olle

Part of Islets, p. 89-101, 2019.

DOI for Characterization of host defense molecules in the human pancreas Download full text (pdf) of Characterization of host defense molecules in the human pancreas

Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells

Bergström, Marcus; Müller, Malin; Karlsson, Marie; Scholz, Hanne et al.

Part of Cell Transplantation, p. 1603-1613, 2019.

DOI for Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells Download full text (pdf) of Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells

Comparison of Clostripain and Neutral Protease as Supplementary Enzymes for Human Islet Isolation

Brandhorst, Heide; Johnson, Paul R.; Moench, Johanna; Kurfuerst, Manfred et al.

Part of Cell Transplantation, p. 176-184, 2019.

DOI for Comparison of Clostripain and Neutral Protease as Supplementary Enzymes for Human Islet Isolation Download full text (pdf) of Comparison of Clostripain and Neutral Protease as Supplementary Enzymes for Human Islet Isolation

Imagining a better future for all people with type 1 diabetes mellitus

Korsgren, Olle; Skyler, Jay S; Skog, Oskar; Sundberg, Frida et al.

Part of Nature Reviews Endocrinology, p. 623-624, 2019.

DOI for Imagining a better future for all people with type 1 diabetes mellitus

Islets for Research: Nothing Is Perfect, but We Can Do Better

Nano, Rita; Kerr-Conte, Julie A.; Bosco, Domenico; Karlsson, Marie et al.

Part of Diabetes, p. 1541-1543, 2019.

DOI for Islets for Research: Nothing Is Perfect, but We Can Do Better

Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence

Skog, Oskar; Klingel, Karin; Roivainen, Merja; Korsgren, Olle

Part of Diabetologia, p. 1097-1099, 2019.

DOI for Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence

Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation

von Zur-Mühlen, Bengt; Lundgren, Torbjorn; Bayman, Levent; Berne, Christian et al.

Part of Transplantation, p. 630-637, 2019.

DOI for Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation Download full text (pdf) of Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation

Protein Kinase R Is Constitutively Expressed in the Human Pancreas

Jonsson, Alexander; Yngve, Erik; Karlsson, Marie; Ingvast, Sofie et al.

Part of Journal of Histochemistry and Cytochemistry, p. 99-105, 2019.

DOI for Protein Kinase R Is Constitutively Expressed in the Human Pancreas

Proton MR spectroscopy of human pancreas allografts

Weis, Jan; Ahlström, Håkan; Korsgren, Olle

Part of Magnetic Resonance Materials in Physics, Biology and Medicine, p. 511-517, 2019.

DOI for Proton MR spectroscopy of human pancreas allografts Download full text (pdf) of Proton MR spectroscopy of human pancreas allografts

Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

Eriksson, Jonas; Roy, Tamal; Sawadjoon, Supaporn; Bachmann, Kim et al.

Part of Nuclear Medicine and Biology, p. 1-10, 2019.

DOI for Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass Download full text (pdf) of Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

Teplizumab in Relatives at Risk for Type 1 Diabetes

Korsgren, Olle; Skog, Oskar; Ludvigsson, Johnny

Part of New England Journal of Medicine, p. 1879-1880, 2019.

DOI for Teplizumab in Relatives at Risk for Type 1 Diabetes

Aetiology of type 1 diabetes: Physiological growth in children affects disease progression

Skog, Oskar; Korsgren, Olle

Part of Diabetes, obesity and metabolism, p. 775-785, 2018.

DOI for Aetiology of type 1 diabetes: Physiological growth in children affects disease progression

Calcium: A Crucial Potentiator for Efficient Enzyme Digestion of the Human Pancreas

Eich, Torsten; Ståhle, Magnus U.; Gustafsson, Bengt; Horneland, Rune et al.

Part of Cell Transplantation, p. 1031-1038, 2018.

DOI for Calcium: A Crucial Potentiator for Efficient Enzyme Digestion of the Human Pancreas Download full text (pdf) of Calcium: A Crucial Potentiator for Efficient Enzyme Digestion of the Human Pancreas

Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer

Gotthardt, Martin; Eizirik, Decio L.; Aanstoot, Henk-Jan; Korsgren, Olle et al.

Part of Diabetologia, p. 2516-2519, 2018.

DOI for Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer

Expression profiles of stress-related genes in islets from donors with progressively impaired glucose metabolism.

Lundberg, Marcus; Stenwall, Per-Anton; Tegehall, Angelica; Korsgren, Olle et al.

Part of Islets, p. 69-79, 2018.

DOI for Expression profiles of stress-related genes in islets from donors with progressively impaired glucose metabolism.

In Vivo Visualization of beta-Cells by Targeting of GPR44

Eriksson, Olof; Johnström, Peter; Cselenyi, Zsolt; Jahan, Mahabuba et al.

Part of Diabetes, p. 182-192, 2018.

DOI for In Vivo Visualization of beta-Cells by Targeting of GPR44

Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT

Abadpour, Shadab; Halvorsen, Bente; Sahraoui, Afaf; Korsgren, Olle et al.

Part of Journal of Molecular Endocrinology, p. 171-183, 2018.

DOI for Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.

Fuchs, Anke; Gliwiński, Mateusz; Grageda, Nathali; Spiering, Rachel et al.

Part of Frontiers in Immunology, 2018.

DOI for Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization. Download full text (pdf) of Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.

No Evidence for Presence of Mucosal-Associated Invariant T Cells in the Insulitic Lesions in Patients Recently Diagnosed with Type 1 Diabetes

Kuric, Enida; Krogvold, Lars; Hanssen, Kristian F.; Dahl-Jorgensen, Knut et al.

Part of American Journal of Pathology, p. 1744-1748, 2018.

DOI for No Evidence for Presence of Mucosal-Associated Invariant T Cells in the Insulitic Lesions in Patients Recently Diagnosed with Type 1 Diabetes

Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4

Eriksson, Olof; Korsgren, Olle; Selvaraju, Ram Kumar; Mollaret, Marjorie et al.

Part of Acta Diabetologica, p. 49-57, 2018.

DOI for Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4 Download full text (pdf) of Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4

Perivascular macrophages regulate blood flow following tissue damage

Vågesjö, Evelina; Seignez, Cedric; Christoffersson, Gustaf; Herrera Hidalgo, Carmen et al.

Part of European Journal of Clinical Investigation, p. 44-45, 2018.

DOI for Perivascular macrophages regulate blood flow following tissue damage

The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass.

Jahan, Mahabuba; Johnström, Peter; Selvaraju, Ramkumar; Svedberg, Marie et al.

Part of EJNMMI Research, 2018.

DOI for The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass. Download full text (pdf) of The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass.

Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus

Carlsson, Per-Ola; Espes, Daniel; Sedigh, Amir; Rotem, Avi et al.

Part of American Journal of Transplantation, p. 1735-1744, 2018.

DOI for Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus Download full text (pdf) of Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus

[(11)C]5-Hydroxy-Tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes

Carlbom, Lina; Espes, Daniel; Lubberink, Mark; Martinell, Mats et al.

Part of Diabetes, p. 1286-1292, 2017.

DOI for [(11)C]5-Hydroxy-Tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes

Characterization of resident lymphocytes in human pancreatic islets

Radenkovic, M; Uvebrant, K; Skog, Oskar; Sarmiento, L et al.

Part of Clinical and Experimental Immunology, p. 418-427, 2017.

DOI for Characterization of resident lymphocytes in human pancreatic islets

Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345

Skog, Oskar; Korsgren, Olle

Part of Diabetes, p. e8-e9, 2017.

DOI for Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345

Cost and clinical outcome of islet transplantation in Norway 2010-2015

Schive, Simen W.; Foss, Aksel; Sahraoui, Afaf; Kloster-Jensen, Kristine et al.

Part of Clinical Transplantation, 2017.

DOI for Cost and clinical outcome of islet transplantation in Norway 2010-2015

Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes

Kuric, Enida; Seiron, Peter; Krogvold, Lars; Edwin, Bjørn et al.

Part of American Journal of Pathology, p. 581-588, 2017.

DOI for Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes

Direct Substrate Delivery into Mitochondrial-Fission Deficient Pancreatic Islets Rescues Insulin Secretion

Kabra, Uma D; Pfuhlmann, Katrin; Migliorini, Adriana; Keipert, Susanne et al.

Part of Diabetes, p. 1247-1257, 2017.

DOI for Direct Substrate Delivery into Mitochondrial-Fission Deficient Pancreatic Islets Rescues Insulin Secretion

Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis

Abadpour, Shadab; Göpel, Sven O.; Schive, Simen W.; Korsgren, Olle et al.

Part of Scientific Reports, 2017.

DOI for Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis Download full text (pdf) of Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis

Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo

Schive, Simen W.; Mirlashari, Mohammad Reza; Hasvold, Grete; Wang, Mengyu et al.

Part of Cell Medicine, p. 103-116, 2017.

DOI for Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo

Insulitis in human diabetes: a histological evaluation of donor pancreases

Lundberg, Marcus; Seiron, Peter; Ingvast, Sofie; Korsgren, Olle et al.

Part of Diabetologia, p. 346-353, 2017.

DOI for Insulitis in human diabetes: a histological evaluation of donor pancreases Download full text (pdf) of Insulitis in human diabetes: a histological evaluation of donor pancreases

Islet Encapsulation: Physiological Possibilities and Limitations

Korsgren, Olle

Part of Diabetes, p. 1748-1754, 2017.

DOI for Islet Encapsulation: Physiological Possibilities and Limitations

Multicenter Assessment of Animal-free Collagenase AF-1 for Human Islet Isolation

Brandhorst, Daniel; Parnaud, Geraldine; Friberg, Andrew; Lavallard, Vanessa et al.

Part of Cell Transplantation, p. 1688-1693, 2017.

DOI for Multicenter Assessment of Animal-free Collagenase AF-1 for Human Islet Isolation Download full text (pdf) of Multicenter Assessment of Animal-free Collagenase AF-1 for Human Islet Isolation

Pancreatectomy and Islet Autotransplantation After Combined Split Liver Transplantation and Pancreaticoduodenectomy: A Case Report

Horneland, R.; Guvag, S.; Korsgren, Olle; Aandahl, E.

Part of American Journal of Transplantation, p. 693-694, 2017.

DOI for Pancreatectomy and Islet Autotransplantation After Combined Split Liver Transplantation and Pancreaticoduodenectomy: A Case Report

Pre-transplantation ³¹P-magnetic resonance spectroscopy for quality assessment of human pancreatic grafts: A feasibility study

Carlbom, Lina; Weis, Jan; Johansson, Lars; Korsgren, Olle et al.

Part of Magnetic Resonance Imaging, p. 98-102, 2017.

DOI for Pre-transplantation ³¹P-magnetic resonance spectroscopy for quality assessment of human pancreatic grafts: A feasibility study

Quantifying the Effects of Different Neutral Proteases on Human Islet Integrity

Brandhorst, Heide; Johnson, Paul R. V.; Korsgren, Olle; Brandhorst, Daniel

Part of Cell Transplantation, p. 1733-1741, 2017.

DOI for Quantifying the Effects of Different Neutral Proteases on Human Islet Integrity Download full text (pdf) of Quantifying the Effects of Different Neutral Proteases on Human Islet Integrity

Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Reply to Campbell-Thompson ML, Atkinson MA, Butler AE et al [letter].

Lundberg, Marcus; Seiron, Peter; Ingvast, Sofie; Korsgren, Olle et al.

Part of Diabetologia, p. 756-757, 2017.

DOI for Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Reply to Campbell-Thompson ML, Atkinson MA, Butler AE et al [letter].

An Apparent Deficiency of Lymphatic Capillaries in the Islets of Langerhans in the Human Pancreas

Korsgren, Erik; Korsgren, Olle

Part of Diabetes, p. 1004-1008, 2016.

DOI for An Apparent Deficiency of Lymphatic Capillaries in the Islets of Langerhans in the Human Pancreas

An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets

Domsgen, Erna; Lind, Katharina; Kong, Lingjia; Huhn, Michael H. et al.

Part of Scientific Reports, 2016.

DOI for An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets Download full text (pdf) of An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets

Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs

Rydén, Anneli; Nyman, Gorel; Nalin, Lovisa; Andreasson, Susanne et al.

Part of Nuclear Medicine and Biology, p. 397-402, 2016.

DOI for Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs

Characterization of innate immunity in an extended whole blood model of human islet allotransplantation

Hårdstedt, Maria; Lindblom, Susanne; Karlsson-Para, Alex; Nilsson, Bo et al.

Part of Cell Transplantation, p. 503-515, 2016.

DOI for Characterization of innate immunity in an extended whole blood model of human islet allotransplantation

Comparison of Neutral Proteases and Collagenase Class I as Essential Enzymes for Human Islet Isolation

Brandhorst, Heide; Kurfuerst, Manfred; Johnson, Paul R.; Korsgren, Olle et al.

Part of TRANSPLANTATION DIRECT, 2016.

DOI for Comparison of Neutral Proteases and Collagenase Class I as Essential Enzymes for Human Islet Isolation Download full text (pdf) of Comparison of Neutral Proteases and Collagenase Class I as Essential Enzymes for Human Islet Isolation

Evaluation of Perfluorohexyloctane/Polydimethylsiloxane for Pancreas Preservation for Clinical Islet Isolation and Transplantation

Ståhle, Magnus; Foss, Aksel; Gustafsson, Bengt; Lempinen, Marko et al.

Part of Cell Transplantation, p. 2269-2276, 2016.

DOI for Evaluation of Perfluorohexyloctane/Polydimethylsiloxane for Pancreas Preservation for Clinical Islet Isolation and Transplantation Download full text (pdf) of Evaluation of Perfluorohexyloctane/Polydimethylsiloxane for Pancreas Preservation for Clinical Islet Isolation and Transplantation

Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of beta-Cell Replacement

Markmann, James F.; Bartlett, Stephen T.; Johnson, Paul; Korsgren, Olle et al.

Part of Transplantation, p. E25-E31, 2016.

DOI for Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of beta-Cell Replacement

Factors impeding the discovery of an intervention-based treatment for type 1 diabetes

von Herrath, M. G.; Korsgren, Olle; Atkinson, M. A.

Part of Clinical and Experimental Immunology, p. 1-7, 2016.

DOI for Factors impeding the discovery of an intervention-based treatment for type 1 diabetes

First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes - Chapter 4: pre-clinical efficacy and complication data required to justify a clinical trial

Cooper, David K. C.; Bottino, Rita; Gianello, Pierre; Graham, Melanie et al.

Part of Xenotransplantation, p. 46-52, 2016.

DOI for First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes - Chapter 4: pre-clinical efficacy and complication data required to justify a clinical trial

Glucose Effectiveness: The Mouse Trap in the Development of Novel beta-Cell Replacement Therapies

Korsgren, Erik; Korsgren, Olle

Part of Transplantation, p. 111-115, 2016.

DOI for Glucose Effectiveness: The Mouse Trap in the Development of Novel beta-Cell Replacement Therapies

GPR44 is a pancreatic protein restricted to the human beta cell

Hellström-Lindahl, Ewa; Danielsson, Angelika; Pontén, Fredrik; Czernichow, Paul et al.

Part of Acta Diabetologica, p. 413-421, 2016.

DOI for GPR44 is a pancreatic protein restricted to the human beta cell

Identification of proliferative and mature beta-cells in the islets of Langerhans

Bader, Erik; Migliorini, Adriana; Gegg, Moritz; Moruzzi, Noah et al.

Part of Nature, p. 430-+, 2016.

DOI for Identification of proliferative and mature beta-cells in the islets of Langerhans

Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes

Krogvold, Lars; Wiberg, Anna; Edwin, Bjørn; Buanes, Trond et al.

Part of Diabetologia, p. 492-501, 2016.

DOI for Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes

National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities

Ricordi, Camillo; Goldstein, Julia S.; Balamurugan, A. N.; Szot, Gregory L. et al.

Part of Diabetes, p. 3418-3428, 2016.

DOI for National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities

Pancreatic perfusion and subsequent response to glucose in healthy individuals and patients with type 1 diabetes

Carlbom, Lina; Espes, Daniel; Lubberink, Mark; Eriksson, Olof et al.

Part of Diabetologia, p. 1968-1972, 2016.

DOI for Pancreatic perfusion and subsequent response to glucose in healthy individuals and patients with type 1 diabetes

Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia

Hering, Bernhard J.; Clarke, William R.; Bridges, Nancy D.; Eggerman, Thomas L. et al.

Part of Diabetes Care, p. 1230-1240, 2016.

DOI for Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia

Positron Emission Tomography to assess the outcome of intraportal islet transplantation

Eriksson, Olof; Selvaraju, Ramkumar; Eich, Torsten; Willny, Mariam et al.

Part of Diabetes, p. 2482-2489, 2016.

DOI for Positron Emission Tomography to assess the outcome of intraportal islet transplantation

Report from IPITA-TTS Opinion Leaders Meeting on the Future of beta-Cell Replacement

Bartlett, Stephen T.; Markmann, James F.; Johnson, Paul; Korsgren, Olle et al.

Part of Transplantation, p. S1-S44, 2016.

DOI for Report from IPITA-TTS Opinion Leaders Meeting on the Future of beta-Cell Replacement Download full text (pdf) of Report from IPITA-TTS Opinion Leaders Meeting on the Future of beta-Cell Replacement

Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids

Kloster-Jensen, Kristine; Sahraoui, Afaf; Vethe, Nils Tore; Korsgren, Olle et al.

Part of Journal of Diabetes Research, 2016.

DOI for Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids Download full text (pdf) of Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids

Type 1 Diabetes Mellitus Donor Mesenchymal. Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro

Davies, Lindsay C.; Alm, Jessica J.; Heldring, Nina; Moll, Guido et al.

Part of Stem Cells Translational Medicine, p. 1485-1495, 2016.

DOI for Type 1 Diabetes Mellitus Donor Mesenchymal. Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro

A novel model for studies of blood-mediated long-term responses to cellular transplants

Hårdstedt, Maria; Lindblom, Susanne; Hong, Jaan; Nilsson, Bo et al.

Part of Upsala Journal of Medical Sciences, p. 28-39, 2015.

DOI for A novel model for studies of blood-mediated long-term responses to cellular transplants

Characterization of human organ donors testing positive for type 1 diabetes-associated autoantibodies

Wiberg, Anna; Granstam, Anna; Ingvast, Sofie; Harkonen, T. et al.

Part of Clinical and Experimental Immunology, p. 278-288, 2015.

DOI for Characterization of human organ donors testing positive for type 1 diabetes-associated autoantibodies

Clostripain, the Missing Link in the Enzyme Blend for Efficient Human Islet Isolation

Ståhle, Magnus; Foss, Aksel; Gustafsson, Bengt; Lempinen, Marko et al.

Part of Transplantation Direct, p. 1-6, 2015.

DOI for Clostripain, the Missing Link in the Enzyme Blend for Efficient Human Islet Isolation

Detection of a low-grade enteroviral infection in the islets of Langerhans of living patients newly diagnosed with type 1 diabetes

Krogvold, Lars; Edwin, Bjørn; Buanes, Trond; Frisk, Gun et al.

Part of Diabetes, p. 1682-1687, 2015.

DOI for Detection of a low-grade enteroviral infection in the islets of Langerhans of living patients newly diagnosed with type 1 diabetes

Expression of Human Leukocyte Antigen Class I in Endocrine and Exocrine Pancreatic Tissue at Onset of Type 1 Diabetes

Skog, Oskar; Korsgren, Stella; Wiberg, Anna; Danielsson, Angelika et al.

Part of American Journal of Pathology, p. 129-138, 2015.

DOI for Expression of Human Leukocyte Antigen Class I in Endocrine and Exocrine Pancreatic Tissue at Onset of Type 1 Diabetes

Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: Results From the DiViD Study

Krogvold, Lars; Skog, Oskar; Sundström, Görel; Edwin, Bjorn et al.

Part of Diabetes, p. 2506-2512, 2015.

DOI for Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: Results From the DiViD Study

Graft function 1 year after pregnancy in an islet-transplanted patient

Schive, Simen W.; Scholz, Hanne; Sahraoui, Afaf; Kloster-Jensen, Kristine et al.

Part of Transplant International, p. 1235-1239, 2015.

DOI for Graft function 1 year after pregnancy in an islet-transplanted patient

Human islet distribution programme for basic research: activity over the last 5 years

Nano, Rita; Bosco, Domenico; Kerr-Conte, Julie A.; Karlsson, Marie et al.

Part of Diabetologia, p. 1138-1140, 2015.

DOI for Human islet distribution programme for basic research: activity over the last 5 years

Identification of potential circulating beta cell biomarkers

Hansson, S. F.; Vachet, P.; Hammar, M.; Korsgren, Olle et al.

Part of Diabetologia, p. S149-S150, 2015.

Immunological shielding by induced recruitment of regulatory T lymphocytes delays rejection of islets transplanted to muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Waldén, Tomas B; Carlsson, Per-Ola et al.

Part of Cell Transplantation, p. 263-276, 2015.

DOI for Immunological shielding by induced recruitment of regulatory T lymphocytes delays rejection of islets transplanted to muscle

Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Waldén, Tomas B; Carlsson, Per-Ola et al.

Part of Cell Transplantation, p. 263-276, 2015.

DOI for Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle

In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome

Simonson, Oscar E.; Mougiakakos, Dimitrios; Heldring, Nina; Bassi, Giulio et al.

Part of Stem Cells Translational Medicine, p. 1199-1213, 2015.

DOI for In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome