Publications in DiVA – Fredrik Pontén
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An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers
Part of EBioMedicine, 2023.
DOI for An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers Download full text (pdf) of An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers
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Next generation pan-cancer blood proteome profiling using proximity extension assay
Part of Nature Communications, 2023.
DOI for Next generation pan-cancer blood proteome profiling using proximity extension assay Download full text (pdf) of Next generation pan-cancer blood proteome profiling using proximity extension assay
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Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer
Part of European Journal of Cancer, p. 40-52, 2023.
DOI for Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer Download full text (pdf) of Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer
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Antibody Validation for Estrogen Receptor Beta
Part of Estrogen Receptors. Methods in Molecular Biology, p. 1-23, 2022.
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Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors
Part of Annals of Diagnostic Pathology, 2022.
DOI for Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors Download full text (pdf) of Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors
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Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level
Part of Nature Communications, 2022.
DOI for Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level Download full text (pdf) of Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level
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Annotation of pituitary neuroendocrine tumors with genome-wide expression analysis
Part of Acta neuropathologica communications, 2021.
DOI for Annotation of pituitary neuroendocrine tumors with genome-wide expression analysis
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ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.
Part of Neuro-Oncology, p. 398-411, 2021.
DOI for ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma. Download full text (pdf) of ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.
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Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer
Part of Journal of Pathology, p. 243-256, 2021.
DOI for Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer Download full text (pdf) of Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer
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The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor beta signaling
Part of Oncogene, p. 3748-3765, 2021.
DOI for The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor beta signaling Download full text (pdf) of The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor beta signaling
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The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types
Part of EBioMedicine, 2021.
DOI for The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types Download full text (pdf) of The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types
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Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy
Part of JOURNAL OF NEUROMUSCULAR DISEASES, p. 231-246, 2020.
DOI for Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy Download full text (pdf) of Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy
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CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup
Part of Frontiers in Oncology, 2020.
DOI for CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup Download full text (pdf) of CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup
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Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study
Part of Acta Oncologica, p. 284-290, 2020.
DOI for Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study Download full text (pdf) of Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study
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Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis
Part of Acta Oncologica, p. 417-426, 2020.
DOI for Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis Download full text (pdf) of Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis
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Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues
Part of Journal of Histochemistry and Cytochemistry, p. 515-529, 2020.
DOI for Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues
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A deep proteome and transcriptome abundance atlas of 29 healthy human tissues
Part of Molecular Systems Biology, 2019.
DOI for A deep proteome and transcriptome abundance atlas of 29 healthy human tissues Download full text (pdf) of A deep proteome and transcriptome abundance atlas of 29 healthy human tissues
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Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients
Part of Cancer Medicine, p. 3623-3635, 2019.
DOI for Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients Download full text (pdf) of Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients
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LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer
Part of International Journal of Cancer, p. 901-915, 2019.
DOI for LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer Download full text (pdf) of LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer
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Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC
Part of Journal of Thoracic Oncology, p. 628-640, 2019.
DOI for Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC Download full text (pdf) of Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC
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Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues
Part of Molecular Systems Biology, 2019.
DOI for Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues Download full text (pdf) of Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues
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Stroma-normalised vessel density predicts benefit from adjuvant fluorouracil-based chemotherapy in patients with stage II/III colon cancer
Part of British Journal of Cancer, p. 303-311, 2019.
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Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles
Part of Scientific Reports, 2019.
DOI for Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles Download full text (pdf) of Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles
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Tumoral pyruvate kinase L/R as a predictive marker for the treatment of renal cancer patients with sunitinib and sorafenib
Part of Journal of Cancer, p. 3224-3231, 2019.
DOI for Tumoral pyruvate kinase L/R as a predictive marker for the treatment of renal cancer patients with sunitinib and sorafenib Download full text (pdf) of Tumoral pyruvate kinase L/R as a predictive marker for the treatment of renal cancer patients with sunitinib and sorafenib
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Combined ASRGL1 and p53 immunohistochemistry as an independent predictor of survival in endometrioid endometrial carcinoma
Part of Gynecologic Oncology, p. 173-180, 2018.
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Mining the Human Tissue Proteome for Protein Citrullination
Part of Molecular & Cellular Proteomics, p. 1378-1391, 2018.
DOI for Mining the Human Tissue Proteome for Protein Citrullination
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Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage
Part of JACC-BASIC TO TRANSLATIONAL SCIENCE, p. 464-480, 2018.
DOI for Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage Download full text (pdf) of Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage
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U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.
Part of Acta Oncologica, p. 187-194, 2018.
DOI for U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden. Download full text (pdf) of U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.
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A nonsense mutation in CEP55 defines a new locus for a Meckel-like syndrome, an autosomal recessive lethal fetal ciliopathy.
Part of Clinical Genetics, p. 510-516, 2017.
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A specific antibody to detect transcription factor T-Pit: a reliable marker of corticotroph cell differentiation and a tool to improve the classification of pituitary neuroendocrine tumours
Part of Acta Neuropathologica, p. 675-677, 2017.
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A subcellular map of the human proteome
Part of Science, 2017.
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A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma
Part of BMC Cancer, 2017.
DOI for A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma Download full text (pdf) of A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma
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Breast cancer in young women and prognosis: How important are proliferation markers?
Part of European Journal of Cancer, p. 278-289, 2017.
DOI for Breast cancer in young women and prognosis: How important are proliferation markers?
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Cetuximab sensitivity of head and neck squamous cell carcinoma xenografts is associated with treatment-induced reduction in EGFR, pEGFR, and pSrc.
Part of Journal of Oral Pathology & Medicine, p. 717-724, 2017.
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High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer
Part of PLOS ONE, 2017.
DOI for High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer Download full text (pdf) of High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer
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Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential
Part of Frontiers in Oncology, 2017.
DOI for Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential Download full text (pdf) of Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential
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Principles of Systems Biology, No. 21: Editorial
Part of CELL SYSTEMS, p. 158-160, 2017.
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Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters.
Part of Modern Pathology, p. 964-977, 2017.
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Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression
Part of OncoTarget, p. 24815-24827, 2017.
DOI for Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression Download full text (pdf) of Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression
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Serotonin, ATRX, and DAXX Expression in Pituitary Adenomas: Markers in the Differential Diagnosis of Neuroendocrine Tumors of the Sellar Region.
Part of American Journal of Surgical Pathology, p. 1238-1246, 2017.
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Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients
Part of Journal of Cancer, p. 3975-3983, 2017.
DOI for Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients Download full text (pdf) of Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients
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Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib
Part of Journal of Cancer Research and Clinical Oncology, p. 961-970, 2017.
DOI for Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib Download full text (pdf) of Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib
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A stromal cell population in the large intestine identified by tissue factor expression that is lost during colorectal cancer progression
Part of Thrombosis and Haemostasis, p. 1050-1059, 2016.
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ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer
Part of BMC Cancer, 2016.
DOI for ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer Download full text (pdf) of ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer
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Extension of diffuse low-grade gliomas beyond radiological borders as shown by the coregistration of histopathological and magnetic resonance imaging data
Part of Journal of Neurosurgery, p. 1155-1166, 2016.
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Gene-specific correlation of RNA and protein levels in human cells and tissues
Part of Molecular Systems Biology, 2016.
DOI for Gene-specific correlation of RNA and protein levels in human cells and tissues Download full text (pdf) of Gene-specific correlation of RNA and protein levels in human cells and tissues
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GPR44 is a pancreatic protein restricted to the human beta cell
Part of Acta Diabetologica, p. 413-421, 2016.
DOI for GPR44 is a pancreatic protein restricted to the human beta cell
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Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages
Part of Cancer Research, p. 3166-3178, 2016.
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Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer
Part of BMC Cancer, 2016.
DOI for Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer Download full text (pdf) of Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer
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Long-term outcome in young women with breast cancer: a population-based study
Part of Breast Cancer Research and Treatment, p. 131-143, 2016.
DOI for Long-term outcome in young women with breast cancer: a population-based study Download full text (pdf) of Long-term outcome in young women with breast cancer: a population-based study
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Oncogene-Induced Senescence in Pituitary Adenomas-an Immunohistochemical Study.
Part of Endocrine pathology, p. 1-11, 2016.
DOI for Oncogene-Induced Senescence in Pituitary Adenomas-an Immunohistochemical Study.
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PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.
Part of OncoTarget, p. 72431-72442, 2016.
DOI for PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status. Download full text (pdf) of PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.
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SATB2 is expressed in Merkel cell carcinoma
Part of Archives of Dermatological Research, p. 449-454, 2016.
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A prognosis based classification of undifferentiated uterine sarcomas: Identification of mitotic index, hormone receptors and YWHAE-FAM22 translocation status as predictors of survival
Part of International Journal of Cancer, p. 1608-1618, 2015.
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A Tissue-Based Map of the Human Proteome
Part of Scandinavian Journal of Immunology, p. 329-329, 2015.
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ALK Rearrangements in Non-Small Cell Lung Cancer: Comprehensive Integration of Genomic, Gene Expression and Protein Analysis
Part of Journal of Thoracic Oncology, p. S298-S298, 2015.
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Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer
Part of PLOS ONE, 2015.
DOI for Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer Download full text (pdf) of Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer
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Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium
Part of Nucleic Acids Research, p. 6787-6798, 2015.
DOI for Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium Download full text (pdf) of Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium
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Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex
Part of PLOS ONE, 2015.
DOI for Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex Download full text (pdf) of Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex
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Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival
Part of Cancer Research, p. 4504-4516, 2015.
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Expression of Human Skin-Specific Genes Defined by Transcriptomics and Antibody-Based Profiling
Part of Journal of Histochemistry and Cytochemistry, p. 129-141, 2015.
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FGF2 as a potential prognostic biomarker for proneural glioma patients
Part of Acta Oncologica, p. 385-394, 2015.
DOI for FGF2 as a potential prognostic biomarker for proneural glioma patients
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Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
Part of OncoTarget, p. 23647-23661, 2015.
DOI for Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells Download full text (pdf) of Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
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Prognostic impact of COX-2 in non-small cell lung cancer: A comprehensive compartment-specific evaluation of tumor and stromal cell expression
Part of Cancer Letters, p. 837-845, 2015.
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The Crux of Molecular Prognostications in NSCLC: An Optimized Biomarker Panel Fails to Outperform Clinical Parameters
Part of Journal of Thoracic Oncology, p. S712-S713, 2015.
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The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling
Part of BMC Genomics, 2015.
DOI for The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling Download full text (pdf) of The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling
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The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling.
Part of Journal of gastroenterology, p. 46-57, 2015.
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The Identification of Therapeutic Targets in Lung Cancer Based on Transcriptomic and Proteomic Characterization of Cancer-Testis Antigens
Part of Journal of Thoracic Oncology, p. S256-S256, 2015.
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The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling
Part of PLOS ONE, 2015.
DOI for The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling Download full text (pdf) of The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling
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Tissue-based map of the human proteome
Part of Science, p. 394-+, 2015.
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Tumor Vessel Up-Regulation of INSR Revealed by Single-Cell Expression Analysis of the Tyrosine Kinome and Phosphatome in Human Cancers
Part of American Journal of Pathology, p. 1600-1609, 2015.
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A study of embryonic stem cell-related proteins in human astrocytomas: Identification of Nanog as a predictor of survival
Part of International Journal of Cancer, p. 1123-1131, 2014.