Publications in DiVA – Fredrik Pontén

An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers

Mezheyeuski, Artur; Backman, Max; Mattsson, Johanna Sofia Margareta; Martin-Bernabe, Alfonso et al.

Part of EBioMedicine, 2023.

DOI for An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers Download full text (pdf) of An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers

Next generation pan-cancer blood proteome profiling using proximity extension assay

Alvez, Maria Bueno; Edfors, Fredrik; von Feilitzen, Kalle; Zwahlen, Martin et al.

Part of Nature Communications, 2023.

DOI for Next generation pan-cancer blood proteome profiling using proximity extension assay Download full text (pdf) of Next generation pan-cancer blood proteome profiling using proximity extension assay

Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer

Backman, Max; Strell, Carina; Lindberg, Amanda; Mattsson, Johanna Sofia Margareta et al.

Part of European Journal of Cancer, p. 40-52, 2023.

DOI for Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer Download full text (pdf) of Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer

A human adipose tissue cell-type transcriptome atlas

Norreen-Thorsen, Marthe; Struck, Eike Christopher; Oling, Sofia; Zwahlen, Martin et al.

Part of Cell reports, 2022.

DOI for A human adipose tissue cell-type transcriptome atlas Download full text (pdf) of A human adipose tissue cell-type transcriptome atlas

Antibody Validation for Estrogen Receptor Beta

Birgersson, Madeleine; Katona, Borbala; Lindskog, Cecilia; Pontén, Fredrik et al.

Part of Estrogen Receptors. Methods in Molecular Biology, p. 1-23, 2022.

DOI for Antibody Validation for Estrogen Receptor Beta

Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors

Bergman-Larsson, Julia; Gustafsson, Sofie; Méar, Loren; Huvila, Jutta et al.

Part of Annals of Diagnostic Pathology, 2022.

DOI for Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors Download full text (pdf) of Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors

Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level

Wang, Fei; Ding, Peiwen; Liang, Xue; Ding, Xiangning et al.

Part of Nature Communications, 2022.

DOI for Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level Download full text (pdf) of Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level

Genome-wide annotation of protein-coding genes in pig

Karlsson, Max; Sjöstedt, Evelina; Oksvold, Per; Sivertsson, Asa et al.

Part of BMC Biology, 2022.

DOI for Genome-wide annotation of protein-coding genes in pig Download full text (pdf) of Genome-wide annotation of protein-coding genes in pig

A single-cell type transcriptomics map of human tissues

Karlsson, Max; Zhang, Cheng; Méar, Loren; Zhong, Wen et al.

Part of Science Advances, 2021.

DOI for A single-cell type transcriptomics map of human tissues Download full text (pdf) of A single-cell type transcriptomics map of human tissues

Annotation of pituitary neuroendocrine tumors with genome-wide expression analysis

Tebani, Abdellah; Jotanovic, Jelena; Hekmati, Neda; Sivertsson, Åsa et al.

Part of Acta neuropathologica communications, 2021.

DOI for Annotation of pituitary neuroendocrine tumors with genome-wide expression analysis

ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.

Huang, Hua; Georganaki, Maria; Conze, Lei Liu; Laviña, Bàrbara et al.

Part of Neuro-Oncology, p. 398-411, 2021.

DOI for ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma. Download full text (pdf) of ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.

Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer

Backman, Max; La Fleur, Linnea; Kurppa, Pinja; Djureinovic, Dijana et al.

Part of Journal of Pathology, p. 243-256, 2021.

DOI for Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer Download full text (pdf) of Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer

Spatiotemporal dissection of the cell cycle with single-cell proteogenomics

Mahdessian, Diana; Cesnik, Anthony J.; Gnann, Christian; Danielsson, Frida et al.

Part of Nature, p. 649-654, 2021.

DOI for Spatiotemporal dissection of the cell cycle with single-cell proteogenomics

The Immune Landscape of Colorectal Cancer

Mezheyeuski, Artur; Micke, Patrick; Martin-Bernabe, Alfonso; Backman, Max et al.

Part of Cancers, 2021.

DOI for The Immune Landscape of Colorectal Cancer Download full text (pdf) of The Immune Landscape of Colorectal Cancer

The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor beta signaling

Papoutsoglou, Panagiotis; Rodrigues Junior, Dorival Mendes; Morén, Anita; Bergman, Andrew et al.

Part of Oncogene, p. 3748-3765, 2021.

DOI for The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor beta signaling Download full text (pdf) of The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor beta signaling

The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types

Micke, Patrick; Strell, Carina; Mattsson, Johanna Sofia Margareta; Martin-Bernabe, Alfonso et al.

Part of EBioMedicine, 2021.

DOI for The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types Download full text (pdf) of The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types

An atlas of the protein-coding genes in the human, pig, and mouse brain

Sjostedt, Evelina; Zhong, Wen; Fagerberg, Linn; Karlsson, Max et al.

Part of Science, p. 1090-+, 2020.

DOI for An atlas of the protein-coding genes in the human, pig, and mouse brain

Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy

Strandberg, Kristin; Ayoglu, Burcu; Roos, Andreas; Reza, Mojgan et al.

Part of JOURNAL OF NEUROMUSCULAR DISEASES, p. 231-246, 2020.

DOI for Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy Download full text (pdf) of Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy

CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup

Aasebo, Kristine; Dragomir, Anca; Sundström, Magnus; Mezheyeuski, Artur et al.

Part of Frontiers in Oncology, 2020.

DOI for CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup Download full text (pdf) of CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup

Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study

Mezheyeuski, Artur; Pontén, Fredrik; Edqvist, Per-Henrik D; Sundström, Magnus et al.

Part of Acta Oncologica, p. 284-290, 2020.

DOI for Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study Download full text (pdf) of Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study

Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis

Nunes, Luís; Aasebø, Kristine; Mathot, Lucy; Ljungström, Viktor et al.

Part of Acta Oncologica, p. 417-426, 2020.

DOI for Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis Download full text (pdf) of Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis

Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues

Lindskog, Cecilia; Backman, Max; Zieba, Agata; Asplund, Anna et al.

Part of Journal of Histochemistry and Cytochemistry, p. 515-529, 2020.

DOI for Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues

A deep proteome and transcriptome abundance atlas of 29 healthy human tissues

Wang, Dongxue; Eraslan, Basak; Wieland, Thomas; Hallstrom, Bjorn et al.

Part of Molecular Systems Biology, 2019.

DOI for A deep proteome and transcriptome abundance atlas of 29 healthy human tissues Download full text (pdf) of A deep proteome and transcriptome abundance atlas of 29 healthy human tissues

A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

Uhlen, Mathias; Karlsson, Max J.; Zhong, Wen; Tebani, Abdellah et al.

Part of Science, p. 1471-+, 2019.

DOI for A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients

Aasebö, Kristine Ö.; Dragomir, Anca; Sundström, Magnus; Mezheyeuski, Artur et al.

Part of Cancer Medicine, p. 3623-3635, 2019.

DOI for Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients Download full text (pdf) of Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients

LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer

Cadenas, Cristina; Vosbeck, Sonja; Edlund, Karolina; Grgas, Katharina et al.

Part of International Journal of Cancer, p. 901-915, 2019.

DOI for LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer Download full text (pdf) of LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer

Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC

Edlund, Karolina; Madjar, Katrin; Mattsson, Johanna Sofia Margareta; Djureinovic, Dijana et al.

Part of Journal of Thoracic Oncology, p. 628-640, 2019.

DOI for Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC Download full text (pdf) of Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC

Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues

Eraslan, Basak; Wang, Dongxue; Gusic, Mirjana; Prokisch, Holger et al.

Part of Molecular Systems Biology, 2019.

DOI for Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues Download full text (pdf) of Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues

Stroma-normalised vessel density predicts benefit from adjuvant fluorouracil-based chemotherapy in patients with stage II/III colon cancer

Mezheyeuski, Artur; Hrynchyk, Ina; Herrera, Mercedes; Karlberg, Mia et al.

Part of British Journal of Cancer, p. 303-311, 2019.

DOI for Stroma-normalised vessel density predicts benefit from adjuvant fluorouracil-based chemotherapy in patients with stage II/III colon cancer

Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles

Fredolini, Claudia; Byström, Sanna; Sanchez-Rivera, Laura; Ioannou, Marina et al.

Part of Scientific Reports, 2019.

DOI for Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles Download full text (pdf) of Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles

The human secretome

Uhlen, Mathias; Karlsson, Max J.; Hober, Andreas; Svensson, Anne-Sophie et al.

Part of Science Signaling, 2019.

DOI for The human secretome

Tumoral pyruvate kinase L/R as a predictive marker for the treatment of renal cancer patients with sunitinib and sorafenib

Niinivirta, Marjut; Enblad, Gunilla; Lindskog, Cecilia; Pontén, Fredrik et al.

Part of Journal of Cancer, p. 3224-3231, 2019.

DOI for Tumoral pyruvate kinase L/R as a predictive marker for the treatment of renal cancer patients with sunitinib and sorafenib Download full text (pdf) of Tumoral pyruvate kinase L/R as a predictive marker for the treatment of renal cancer patients with sunitinib and sorafenib

Combined ASRGL1 and p53 immunohistochemistry as an independent predictor of survival in endometrioid endometrial carcinoma

Huvila, Jutta; Laajala, Teemu D.; Edqvist, Per-Henrik D; Mardinoglu, Adil et al.

Part of Gynecologic Oncology, p. 173-180, 2018.

DOI for Combined ASRGL1 and p53 immunohistochemistry as an independent predictor of survival in endometrioid endometrial carcinoma

Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer

Djureinovic, Dijana; Dodig-Crnkovic, Tea; Hellström, Cecilia; Holgersson, Georg et al.

Part of Lung Cancer, p. 157-163, 2018.

DOI for Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer

Immunohistochemistry for transcription factor T-Pit as a tool in diagnostics of corticotroph pituitary tumours

Casar Borota, Olivera; Bollerslev, Jens; Pontén, Fredrik

Part of Pituitary, p. 443-443, 2018.

DOI for Immunohistochemistry for transcription factor T-Pit as a tool in diagnostics of corticotroph pituitary tumours

In situ protein detection with enhanced specificity using DNA-conjugated antibodies and proximity ligation

Zieba, Agata; Ponten, Fredrik; Uhlen, Mathias; Landegren, Ulf

Part of Modern Pathology, p. 253-263, 2018.

DOI for In situ protein detection with enhanced specificity using DNA-conjugated antibodies and proximity ligation

Mining the Human Tissue Proteome for Protein Citrullination

Lee, Chien-Yun; Wang, Dongxue; Wilhelm, Mathias; Zolg, Daniel P. et al.

Part of Molecular & Cellular Proteomics, p. 1378-1391, 2018.

DOI for Mining the Human Tissue Proteome for Protein Citrullination

Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage

Matic, Ljubica Perisic; Iglesias, Maria Jesus; Vesterlund, Mattias; Lengquist, Mariette et al.

Part of JACC-BASIC TO TRANSLATIONAL SCIENCE, p. 464-480, 2018.

DOI for Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage Download full text (pdf) of Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage

U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Glimelius, Bengt; Melin, Beatrice; Enblad, Gunilla; Alafuzoff, Irina et al.

Part of Acta Oncologica, p. 187-194, 2018.

DOI for U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden. Download full text (pdf) of U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

A nonsense mutation in CEP55 defines a new locus for a Meckel-like syndrome, an autosomal recessive lethal fetal ciliopathy.

Bondeson, Marie-Louise; Ericson, Katharina; Gudmundsson, Sanna; Ameur, Adam et al.

Part of Clinical Genetics, p. 510-516, 2017.

DOI for A nonsense mutation in CEP55 defines a new locus for a Meckel-like syndrome, an autosomal recessive lethal fetal ciliopathy.

A pathology atlas of the human cancer transcriptome

Uhlen, Mathias; Zhang, Cheng; Lee, Sunjae; Sjöstedt, Evelina et al.

Part of Science, 2017.

DOI for A pathology atlas of the human cancer transcriptome

A specific antibody to detect transcription factor T-Pit: a reliable marker of corticotroph cell differentiation and a tool to improve the classification of pituitary neuroendocrine tumours

Sjöstedt, Evelina; Bollerslev, Jens; Mulder, Jan; Lindskog, Cecilia et al.

Part of Acta Neuropathologica, p. 675-677, 2017.

DOI for A specific antibody to detect transcription factor T-Pit: a reliable marker of corticotroph cell differentiation and a tool to improve the classification of pituitary neuroendocrine tumours

A subcellular map of the human proteome

Thul, Peter J.; åkesson, Lovisa; Wiking, Mikaela; Mahdessian, Diana et al.

Part of Science, 2017.

DOI for A subcellular map of the human proteome

A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma

Gremel, Gabriela; Djureinovic, Dijana; Niinivirta, Marjut; Laird, Alexander et al.

Part of BMC Cancer, 2017.

DOI for A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma Download full text (pdf) of A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma

Affinity Proteomics Exploration of Melanoma Identifies Proteins in Serum with Associations to T-Stage and Recurrence

Byström, Sanna; Fredolini, Claudia; Edqvist, Per-Henrik D; Nyaiesh, Etienne-Nicholas et al.

Part of Translational Oncology, p. 385-395, 2017.

DOI for Affinity Proteomics Exploration of Melanoma Identifies Proteins in Serum with Associations to T-Stage and Recurrence

Breast cancer in young women and prognosis: How important are proliferation markers?

Fredholm, Hanna; Magnusson, Kristina; Lindstrom, Linda S.; Tobin, Nicholas P. et al.

Part of European Journal of Cancer, p. 278-289, 2017.

DOI for Breast cancer in young women and prognosis: How important are proliferation markers?

Cetuximab sensitivity of head and neck squamous cell carcinoma xenografts is associated with treatment-induced reduction in EGFR, pEGFR, and pSrc.

Jedlinski, Adam; Garvin, Stina; Johansson, Ann-Charlotte; Edqvist, Per-Henrik D et al.

Part of Journal of Oral Pathology & Medicine, p. 717-724, 2017.

DOI for Cetuximab sensitivity of head and neck squamous cell carcinoma xenografts is associated with treatment-induced reduction in EGFR, pEGFR, and pSrc.

High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer

Siesing, Christina; Sorbye, Halfdan; Dragomir, Anca; Pfeiffer, Per et al.

Part of PLOS ONE, 2017.

DOI for High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer Download full text (pdf) of High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer

Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential

Roy, Ananya; Libard, Sylwia; Weishaupt, Holger; Gustavsson, Ida et al.

Part of Frontiers in Oncology, 2017.

DOI for Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential Download full text (pdf) of Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential

Principles of Systems Biology, No. 21: Editorial

Cao, Junyue; Packer, Jonathan; Waterston, Robert; Trapnell, Cole et al.

Part of CELL SYSTEMS, p. 158-160, 2017.

DOI for Principles of Systems Biology, No. 21: Editorial

Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters.

Grinberg, Marianna; Djureinovic, Dijana; Brunnström, Hans R R; Mattsson, Johanna Sofia Margareta et al.

Part of Modern Pathology, p. 964-977, 2017.

DOI for Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters.

Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression

Roy, Ananya; Attarha, Sanaz; Weishaupt, Holger; Edqvist, Per-Henrik et al.

Part of OncoTarget, p. 24815-24827, 2017.

DOI for Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression Download full text (pdf) of Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression

Serotonin, ATRX, and DAXX Expression in Pituitary Adenomas: Markers in the Differential Diagnosis of Neuroendocrine Tumors of the Sellar Region.

Casar Borota, Olivera; Botling, Johan; Granberg, Dan; Stigare, Jerker et al.

Part of American Journal of Surgical Pathology, p. 1238-1246, 2017.

DOI for Serotonin, ATRX, and DAXX Expression in Pituitary Adenomas: Markers in the Differential Diagnosis of Neuroendocrine Tumors of the Sellar Region.

The human adrenal gland proteome defined by transcriptomics and antibody-based profiling

Bergman, Julia; Botling, Johan; Fagerberg, Linn; Hallström, Björn M. et al.

Part of Endocrinology, p. 239-251, 2017.

DOI for The human adrenal gland proteome defined by transcriptomics and antibody-based profiling

Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients

Niinivirta, Marjut; Enblad, Gunilla; Edqvist, Per-Henrik D; Pontén, Fredrik et al.

Part of Journal of Cancer, p. 3975-3983, 2017.

DOI for Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients Download full text (pdf) of Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients

Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib

Niinivirta, Marjut; Enblad, Gunilla; Edqvist, Per-Henrik; Pontén, Fredrik et al.

Part of Journal of Cancer Research and Clinical Oncology, p. 961-970, 2017.

DOI for Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib Download full text (pdf) of Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib

A stromal cell population in the large intestine identified by tissue factor expression that is lost during colorectal cancer progression

Eriksson, Oskar; Asplund, Anna; Hegde, Geeta; Edqvist, Per-Henrik D et al.

Part of Thrombosis and Haemostasis, p. 1050-1059, 2016.

DOI for A stromal cell population in the large intestine identified by tissue factor expression that is lost during colorectal cancer progression

Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome.

Butler, Lynn Marie; Hallström, Björn Mikael; Fagerberg, Linn; Pontén, Fredrik C et al.

Part of Cell systems, p. 287-301.e3, 2016.

DOI for Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome.

ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer

Magnusson, Kristina; Gremel, Gabriela; Rydén, Lisa; Pontén, Victor et al.

Part of BMC Cancer, 2016.

DOI for ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer Download full text (pdf) of ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer

Extension of diffuse low-grade gliomas beyond radiological borders as shown by the coregistration of histopathological and magnetic resonance imaging data

Zetterling, Maria; Roodakker, Kenney Roy; Berntsson, Shala Ghaderi; Edqvist, Per-Henrik D et al.

Part of Journal of Neurosurgery, p. 1155-1166, 2016.

DOI for Extension of diffuse low-grade gliomas beyond radiological borders as shown by the coregistration of histopathological and magnetic resonance imaging data

Gene-specific correlation of RNA and protein levels in human cells and tissues

Edfors, Fredrik; Danielsson, Frida; Hallström, Björn M.; Käll, Lukas et al.

Part of Molecular Systems Biology, 2016.

DOI for Gene-specific correlation of RNA and protein levels in human cells and tissues Download full text (pdf) of Gene-specific correlation of RNA and protein levels in human cells and tissues

GPR44 is a pancreatic protein restricted to the human beta cell

Hellström-Lindahl, Ewa; Danielsson, Angelika; Pontén, Fredrik; Czernichow, Paul et al.

Part of Acta Diabetologica, p. 413-421, 2016.

DOI for GPR44 is a pancreatic protein restricted to the human beta cell

Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages

Wallerius, Majken; Wallmann, Tatjana; Bartish, Margarita; Ostling, Jeanette et al.

Part of Cancer Research, p. 3166-3178, 2016.

DOI for Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages

Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer

Mattsson, Johanna Sofia Margareta; Brunnström, Hans; Jabs, Verena; Edlund, Karolina et al.

Part of BMC Cancer, 2016.

DOI for Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer Download full text (pdf) of Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer

Long-term outcome in young women with breast cancer: a population-based study

Fredholm, Hanna; Magnusson, Kristina; Lindström, Linda S.; Garmo, Hans et al.

Part of Breast Cancer Research and Treatment, p. 131-143, 2016.

DOI for Long-term outcome in young women with breast cancer: a population-based study Download full text (pdf) of Long-term outcome in young women with breast cancer: a population-based study

Oncogene-Induced Senescence in Pituitary Adenomas-an Immunohistochemical Study.

Manojlovic-Gacic, Emilija; Skender-Gazibara, Milica; Popovic, Vera; Soldatovic, Ivan et al.

Part of Endocrine pathology, p. 1-11, 2016.

DOI for Oncogene-Induced Senescence in Pituitary Adenomas-an Immunohistochemical Study.

Profiling cancer testis antigens in non-small-cell lung cancer

Djureinovic, Dijana; Hallström, Bjorn M.; Horie, Masafumi; Mattsson, Johanna Sofia Margareta et al.

Part of JCI INSIGHT, 2016.

DOI for Profiling cancer testis antigens in non-small-cell lung cancer

PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.

Roodakker, Kenney R.; Elsir, Tamador; Edqvist, Per-Henrik D; Hägerstrand, Daniel et al.

Part of OncoTarget, p. 72431-72442, 2016.

DOI for PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status. Download full text (pdf) of PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.

SATB2 is expressed in Merkel cell carcinoma

Fukuhara, Mari; Agnarsdottir, Margret; Edqvist, Per-Henrik; Coter, Anna et al.

Part of Archives of Dermatological Research, p. 449-454, 2016.

DOI for SATB2 is expressed in Merkel cell carcinoma

Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer

Mezheyeuski, Artur; Lindh, Maja Bradic; Guren, Tormod Kyrre; Dragomir, Anca et al.

Part of OncoTarget, p. 41948-41958, 2016.

DOI for Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer

System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis

Pozniak, Yair; Balint-Lahat, Nora; Rudolph, Jan Daniel; Lindskog, Cecilia et al.

Part of CELL SYSTEMS, p. 172-184, 2016.

DOI for System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis

The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene

van Kempen, Leon C. L.; Redpath, Margaret; Elchebly, Mounib; Klein, Kathleen Oros et al.

Part of Science Translational Medicine, 2016.

DOI for The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene

Transcriptomics resources of human tissues and organs

Uhlen, Mathias; Hallstrom, Bjorn M.; Lindskog Bergström, Cecilia; Mardinoglu, Adil et al.

Part of Molecular Systems Biology, 2016.

DOI for Transcriptomics resources of human tissues and organs Download full text (pdf) of Transcriptomics resources of human tissues and organs

Visualization and analysis of gene expression in tissue sections by spatial transcriptomics

Stahl, Patrik L.; Salmen, Fredrik; Vickovic, Sanja; Lundmark, Anna et al.

Part of Science, p. 78-82, 2016.

DOI for Visualization and analysis of gene expression in tissue sections by spatial transcriptomics

A prognosis based classification of undifferentiated uterine sarcomas: Identification of mitotic index, hormone receptors and YWHAE-FAM22 translocation status as predictors of survival

Gremel, Gabriela; Liew, Markus; Hamzei, Farzaneh; Hardell, Elin et al.

Part of International Journal of Cancer, p. 1608-1618, 2015.

DOI for A prognosis based classification of undifferentiated uterine sarcomas: Identification of mitotic index, hormone receptors and YWHAE-FAM22 translocation status as predictors of survival

A Tissue-Based Map of the Human Proteome

Pontén, Fredrik

Part of Scandinavian Journal of Immunology, p. 329-329, 2015.

ALK Rearrangements in Non-Small Cell Lung Cancer: Comprehensive Integration of Genomic, Gene Expression and Protein Analysis

Mattsson, Johanna S. M.; Svensson, Maria A.; Hallström, Björn; Koyi, Hirsh et al.

Part of Journal of Thoracic Oncology, p. S298-S298, 2015.

Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer

O'Hurley, Gillian; Busch, Christer; Fagerberg, Linn; Hallstrom, Bjorn M. et al.

Part of PLOS ONE, 2015.

DOI for Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer Download full text (pdf) of Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer

Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium

Yu, Nancy Yiu-Lin; Hallstrom, Bjorn M.; Fagerberg, Linn; Pontén, Fredrik et al.

Part of Nucleic Acids Research, p. 6787-6798, 2015.

DOI for Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium Download full text (pdf) of Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium

Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex

Sjöstedt, Evelina; Fagerberg, Linn; Hallstrom, Bjorn M.; Haggmark, Anna et al.

Part of PLOS ONE, 2015.

DOI for Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex Download full text (pdf) of Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex

Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Langenkamp, Elise; Zhang, Lei; Lugano, Roberta; Huang, Hua et al.

Part of Cancer Research, p. 4504-4516, 2015.

DOI for Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

Vizoso, Miguel; Ferreira, Humberto J.; Lopez-Serra, Paula; Javier Carmona, F. et al.

Part of Nature Medicine, p. 741-+, 2015.

DOI for Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

Expression of Human Skin-Specific Genes Defined by Transcriptomics and Antibody-Based Profiling

Edqvist, Per-Henrik D; Fagerberg, Linn; Hallström, Björn M; Danielsson, Angelika et al.

Part of Journal of Histochemistry and Cytochemistry, p. 129-141, 2015.

DOI for Expression of Human Skin-Specific Genes Defined by Transcriptomics and Antibody-Based Profiling

FGF2 as a potential prognostic biomarker for proneural glioma patients

Sooman, Linda; Freyhult, Eva; Jaiswal, Archita; Navani, Sanjay et al.

Part of Acta Oncologica, p. 385-394, 2015.

DOI for FGF2 as a potential prognostic biomarker for proneural glioma patients

Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier

Reyahi, Azadeh; Nik, Ali M.; Ghiami, Mozhgan; Gritli-Linde, Amel et al.

Part of Developmental Cell, p. 19-32, 2015.

DOI for Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier

Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells

Roy, Ananya; Coum, Antoine; Marinescu, Voichita D; Põlajeva, Jelena et al.

Part of OncoTarget, p. 23647-23661, 2015.

DOI for Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells Download full text (pdf) of Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells

High BRAF Mutation Frequency and Marked Survival Differences in Subgroups According to KRAS/BRAF Mutation Status and Tumor Tissue Availability in a Prospective Population-Based Metastatic Colorectal Cancer Cohort

Sorbye, Halfdan; Dragomir, Anca; Sundström, Magnus; Pfeiffer, Per et al.

Part of PLOS ONE, 2015.

DOI for High BRAF Mutation Frequency and Marked Survival Differences in Subgroups According to KRAS/BRAF Mutation Status and Tumor Tissue Availability in a Prospective Population-Based Metastatic Colorectal Cancer Cohort

High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes

Dijksterhuis, Jacomijn P.; Arthofer, Elisa; Marinescu, Voichita D.; Nelander, Sven et al.

Part of Experimental Cell Research, p. 280-288, 2015.

DOI for High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes

Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma

Edqvist, Per-Henrik D.; Huvila, Jutta; Forsstrom, Bjorn; Talve, Lauri et al.

Part of Gynecologic Oncology, p. 529-537, 2015.

DOI for Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Zhang, Lei; Kundu, Soumi; Feenstra, Tjerk; Li, Xiujuan et al.

Part of Science Signaling, 2015.

DOI for Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Prognostic impact of COX-2 in non-small cell lung cancer: A comprehensive compartment-specific evaluation of tumor and stromal cell expression

Mattsson, Johanna Sofia Margareta; Bergman, Bengt; Grinberg, Marianna; Edlund, Karolina et al.

Part of Cancer Letters, p. 837-845, 2015.

DOI for Prognostic impact of COX-2 in non-small cell lung cancer: A comprehensive compartment-specific evaluation of tumor and stromal cell expression

The Crux of Molecular Prognostications in NSCLC: An Optimized Biomarker Panel Fails to Outperform Clinical Parameters

Djureinovic, Dijana; Grinberg, Marianna; Mattsson, Johanna Sofia Margareta; Edlund, Karolina et al.

Part of Journal of Thoracic Oncology, p. S712-S713, 2015.

The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling

Lindskog, Cecilia; Linné, Jerker; Fagerberg, Linn; Hallstrom, Bjorn M. et al.

Part of BMC Genomics, 2015.

DOI for The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling Download full text (pdf) of The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling

The Human Endometrium-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling

Zieba, Agata; Sjöstedt, Evelina; Olovsson, Matts; Fagerberg, Linn et al.

Part of Omics, p. 659-668, 2015.

DOI for The Human Endometrium-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling

The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling.

Gremel, Gabriela; Wanders, Alkwin; Cedernaes, Jonathan; Fagerberg, Linn et al.

Part of Journal of gastroenterology, p. 46-57, 2015.

DOI for The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling.

The Identification of Therapeutic Targets in Lung Cancer Based on Transcriptomic and Proteomic Characterization of Cancer-Testis Antigens

Djureinovic, Dijana; Hallström, Björn; Mattsson, Johanna Sofia Margareta; La Fleur, Linnea et al.

Part of Journal of Thoracic Oncology, p. S256-S256, 2015.

The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling

Habuka, Masato; Fagerberg, Linn; Hallström, Björn M.; Pontén, Fredrik et al.

Part of PLOS ONE, 2015.

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Tissue-based map of the human proteome

Uhlen, Mathias; Fagerberg, Linn; Hallstroem, Bjoern M.; Lindskog, Cecilia et al.

Part of Science, p. 394-+, 2015.

DOI for Tissue-based map of the human proteome

Tumor Vessel Up-Regulation of INSR Revealed by Single-Cell Expression Analysis of the Tyrosine Kinome and Phosphatome in Human Cancers

Kiflemariam, Sara; Ljungström, Viktor; Pontén, Fredrik; Sjöblom, Tobias

Part of American Journal of Pathology, p. 1600-1609, 2015.

DOI for Tumor Vessel Up-Regulation of INSR Revealed by Single-Cell Expression Analysis of the Tyrosine Kinome and Phosphatome in Human Cancers

A study of embryonic stem cell-related proteins in human astrocytomas: Identification of Nanog as a predictor of survival

Elsir, Tamador; Edqvist, Per-Henrik; Carlson, Joseph; Ribom, Dan et al.

Part of International Journal of Cancer, p. 1123-1131, 2014.

DOI for A study of embryonic stem cell-related proteins in human astrocytomas: Identification of Nanog as a predictor of survival