Bondeson and Annerén – Next-Generation Sequencing for exploratory research and clinical implementation
The overall aim of our projects is to enable translational research into disease mechanism and improved diagnostics of inherited disorders.
Our research interest is focused on genomic medicine, specifically discovery of genes associated with fundamental developmental processes. Currently we are using Next-Generation Sequencing (NGS) to discover genes associated with unresolved cases of intrauterine fetal death (IUFD) and intellectual disability (ID) disorders.
Knowledge about the underlying genetic causes is important for diagnosis, prognosis, proper treatment and estimation of risk for recurrence. It will also increase our understanding of the molecular processes behind the disorders, which enables future development of novel improved therapies.