Publications – Marcel den Hoed

Publications in DiVA

Publications in PubMed

Selected publications:

  1. Wang Z, Emmerich A, Pillon NJ, Moore T, Hemerich D, Cornelis MC, Mazzaferro E, Broos S, [205 co-authors], Hevener AL, Krook A, Zierath JR, Thomis MAI, Loos RJF, den Hoed M. Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention. Nat Genet, 54: 1332-44, 2022.
  2. Höijer I, Emmanouilidou A, Östlund R, van Schendel R, Bozorgpana S, Tijsterman M, Feuk L, Gyllensten U, den Hoed M* and Ameur A* CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations. Nat Commun, 13:627, 2022.
  3. Mills MC, Tropf FC, Brazel DM, van Zuydam N, Vaez A, eQTLGen Consortium, BIOS Consortium, Human Reproductive Behaviour Consortium, Pers TH, Snieder H, Perry JRB, Ong KK, den Hoed M*, Barban N* and Day FR*. Identification of 371 genetic loci for age at first sex and birth linked to externalizing behaviour. Nat Hum Behav, 5: 1717-1730 2021.
  4. von der Heyde B, Emmanouilidou A, Klingström T, Mazzaferro E, Vicenzi S, Jumaa S, Dethlefsen O, Snieder H, de Geus E, Ingelsson E, Allalou A, Brooke HL, den Hoed M. Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo, image-based, large-scale genetic screen in zebrafish. Sci Rep, 10: 11831, 2020.
  5. Barban N, Jansen R, de Vlaming R, Vaez A, Mandemakers JJ, Tropf FC, [246 co-authors], den Hoed M*, Snieder H*, Mills MC*. Genome-wide analysis identified 12 loci influencing human reproductive behavior. Nat Genet, 48: 1462-1472, 2016 (146).
  6. den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, [253 co-authors], Sibon OC, Milan DJ, Snieder H, Samani NJ, Loos RJ. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet, 45: 621-31, 2013.
  7. Elks CE, den Hoed M, Zhao JH, Sharp SJ, Wareham NJ, Loos RJF and Ong KK. Variability in the heritability of body mass index: a systematic review and meta-regression. Front Endocrinol, 3(29) fendo. 2012.0029, 2012.
  8. den Hoed M, Ekelund U, Brage S, Grøntved A, Zhao J-H, Sharp S, Ong KK, Wareham NJ and Loos RJF. Genetic susceptibility to obesity and related traits in childhood and adolescence; influence of loci identified by genome-wide association studies. Diabetes, 59: 2980-88, 2010.
  9. den Hoed M, Westerterp-Plantenga MS, Bouwman FG, Mariman ECM and Westerterp KR. Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO. Am J Clin Nutr 90:1426-32, 2009.

Last modified: 2023-01-11