Publications Mats Hellström

Publications in DiVA

Selected publications:

  1. Kundu S, Ali MA, Handin N, Padhan N, Larsson J, Karoutsou M, Ban K, Wiśniewski JR, Artursson P, He L, Hellström M, Sjöblom T. Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells. Genome Med. 2018, 10(1):2.
     
  2. Egaña I, Kaito H, Nitzsche A, Becker L, Ballester-Lopez C, Niaudet C, Petkova M, Liu W, Vanlandewijck M, Vernaleken A, Klopstock T, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Rask-Andersen H, Johansson HJ, Lehtiö J, He L, Yildirim AÖ, Hellström M. Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema. German Mouse Clinic Consortium. Sci Rep. 2017, 7(1):15453.
     
  3. Pandzic T, Rendo V, Lim J, Larsson C, Larsson J, Stoimenov I, Kundu S, Ali MA, Hellström M, He L, Lindroth AM, Sjöblom T. Somatic PRDM2 c.4459delA mutations in colorectal cancers control histone methylation and tumor growth.. Oncotarget, 2017, 8(58):98646-98659.
     
  4. Pandzic T, Larsson J, He L, Kundu S, Ban K, Akhtar-Ali M, Hellström AR, Schuh A, Clifford R, Blakemore SJ, Strefford JC, Bauman TS, Lopez-Guillermo A, Campo E, Ljungström V, Mansouri L, Rosenquist R, Sjöblom T and Hellström M. Transposon mutagenesis reveals fludarabine-resistance mechanisms in chronic lymphocytic leukemia.. Clinical Cancer Research, 2016, 22(24):6217-6227.
     
  5. Wallgard E, Nitzsche A, Larsson J, Guo X, Dieterich LC, Dimberg A, Olofsson T, Pontén FC, Mäkinen T, Kalén M, Hellström M. Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development. Dev Dyn. 2012, 241(4):770-86.
     
  6. Kalén M, Heikura T, Karvinen H, Nitzsche A, Weber H, Esser N, Ylä-Herttuala S and Hellström M. Gamma-Secretase Inhibitor Treatment Promotes VEGF-A-Driven Blood Vessel Growth but Disrupts Neovascular Perfusion. PLoS ONE, 2011, 6(4):e18709.
  7. Kalén M, Wallgard E, Asker N, Nasevicius A, Athley E, Billgren E, Larson JD, Wadman SA, Norseng E, Clark KJ, He L, Karlsson-Lindahl L, Häger AK, Weber H, Augustin H, Samuelsson T, Kemmet CK, Utesch CM, Essner JJ, Hackett PB, Hellström M. Combination of reverse and chemical genetic screens reveals angiogenesis inhibitors and targets. Chem Biol. 2009, 16(4):432-41.
     
  8. Hellström M, Phng LK, Hofmann JJ, Wallgard E, Coultas L, Lindblom P, Alva J, Nilsson AK, Karlsson L, Gaiano N, Yoon K, Rossant J, Iruela-Arispe ML, Kalen M, Gerhardt H, Betsholtz C., Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature. 2007, 445(7129):776-80.
     
  9. Hellström M., Gerhardt H., Kalén M., Li, X. Eriksson U., Wolburg H. and Betsholtz C. Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol. 2001, 153(3):543-53.
     
  10. Hellström, M., Kalén, M., Lindahl, P., Abramsson, A. and Betsholtz, C. Role of PDGF-B and PDGFR-b in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development. 1999, 126(14):3047-3055.