New publications from IGP

Exercise reduces intramuscular stress and counteracts muscle weakness in mice with breast cancer

Mader, Theresa; Chaillou, Thomas; Alves, Estela Santos; Jude, Baptiste et al.

Part of Journal of Cachexia, Sarcopenia and Muscle, p. 1151-1163, 2022.

DOI for Exercise reduces intramuscular stress and counteracts muscle weakness in mice with breast cancer Download full text (pdf) of Exercise reduces intramuscular stress and counteracts muscle weakness in mice with breast cancer

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Peptide emulsions in incomplete Freund's adjuvant create effective nurseries promoting egress of systemic CD4(+) and CD8(+) T cells for immunotherapy of cancer

Melssen, Marit M.; Fisher, Caroline T.; Slingluff, Craig L.; Melief, Cornelis J. M.

Part of Journal for ImmunoTherapy of Cancer, 2022.

DOI for Peptide emulsions in incomplete Freund's adjuvant create effective nurseries promoting egress of systemic CD4(+) and CD8(+) T cells for immunotherapy of cancer Download full text (pdf) of Peptide emulsions in incomplete Freund's adjuvant create effective nurseries promoting egress of systemic CD4(+) and CD8(+) T cells for immunotherapy of cancer

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A genomic and morphometric analysis of alpine bumblebees: Ongoing reductions in tongue length but no clear genetic component

Christmas, Matthew; Jones, Julia C.; Olsson, Anna; Wallerman, Ola et al.

Part of Molecular Ecology, p. 1111-1127, 2022.

DOI for A genomic and morphometric analysis of alpine bumblebees: Ongoing reductions in tongue length but no clear genetic component Download full text (pdf) of A genomic and morphometric analysis of alpine bumblebees: Ongoing reductions in tongue length but no clear genetic component

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Application of precision medicine in clinical routine in haematology-Challenges and opportunities

Wasterlid, Tove; Cavelier, Lucia; Haferlach, Claudia; Konopleva, Marina et al.

Part of Journal of Internal Medicine, p. 243-261, 2022.

DOI for Application of precision medicine in clinical routine in haematology-Challenges and opportunities Download full text (pdf) of Application of precision medicine in clinical routine in haematology-Challenges and opportunities

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Investigation of multiple populations highlight VEGFA polymorphisms to modulate anterior cruciate ligament injury

Feldmann, Daneil C.; Rahim, Masouda; Suijkerbuijk, Mathijs A. M.; Laguette, Mary-Jessica N. et al.

Part of Journal of Orthopaedic Research, p. 1604-1612, 2022.

DOI for Investigation of multiple populations highlight VEGFA polymorphisms to modulate anterior cruciate ligament injury
Specification of CNS macrophage subsets occurs postnatally in defined niches

Masuda, Takahiro; Amann, Lukas; Monaco, Gianni; Sankowski, Roman et al.

Part of Nature, p. 740-+, 2022.

DOI for Specification of CNS macrophage subsets occurs postnatally in defined niches
Angiocrine polyamine production regulates adiposity

Monelli, Erika; Villacampa, Pilar; Zabala-Letona, Amaia; Martinez-Romero, Anabel et al.

Part of Nature Metabolism, p. 327-+, 2022.

DOI for Angiocrine polyamine production regulates adiposity
Swedish National Guidelines on Urothelial Carcinoma: 2021 update on non-muscle invasive bladder cancer and upper tract urothelial carcinoma

Liedberg, Fredrik; Kjellstrom, Sofia; Lind, Anna-Karin; Sherif, Amir et al.

Part of Scandinavian journal of urology, p. 137-146, 2022.

DOI for Swedish National Guidelines on Urothelial Carcinoma: 2021 update on non-muscle invasive bladder cancer and upper tract urothelial carcinoma Download full text (pdf) of Swedish National Guidelines on Urothelial Carcinoma: 2021 update on non-muscle invasive bladder cancer and upper tract urothelial carcinoma

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Endothelium-derived lactate is required for pericyte function and blood-brain barrier maintenance

Lee, Heon-Woo; Xu, Yanying; Zhu, Xiaolong; Jang, Cholsoon et al.

Part of EMBO Journal, 2022.

DOI for Endothelium-derived lactate is required for pericyte function and blood-brain barrier maintenance
TP53 mutations at codon 234 are associated with chlorambucil treatment in chronic lymphocytic leukemia

Lazarian, Gregory; Theves, Floriane; Hormi, Myriam; Letestu, Remi et al.

Part of American Journal of Hematology, p. E159-E162, 2022.

DOI for TP53 mutations at codon 234 are associated with chlorambucil treatment in chronic lymphocytic leukemia
Dosimetric robustness of lung tumor photon radiotherapy evaluated from multiple event CT imaging

Olofsson, Nils; Wikström, Kenneth; Flejmer, Anna; Ahnesjö, Anders et al.

Part of Physica medica (Testo stampato), 2022.

DOI for Dosimetric robustness of lung tumor photon radiotherapy evaluated from multiple event CT imaging

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Adjuvant capecitabine-containing chemotherapy benefit and homologous recombination deficiency in early-stage triple-negative breast cancer patients

de Boo, Leonora W.; Jozwiak, Katarzyna; Joensuu, Heikki; Lindman, Henrik et al.

Part of British Journal of Cancer, p. 1401-1409, 2022.

DOI for Adjuvant capecitabine-containing chemotherapy benefit and homologous recombination deficiency in early-stage triple-negative breast cancer patients Download full text (pdf) of Adjuvant capecitabine-containing chemotherapy benefit and homologous recombination deficiency in early-stage triple-negative breast cancer patients

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Advances in immune therapies in hematological malignancies

Mazzarella, Luca; Enblad, Gunilla; Olweus, Johanna; Malmberg, Karl-Johan et al.

Part of Journal of Internal Medicine, p. 205-220, 2022.

DOI for Advances in immune therapies in hematological malignancies Download full text (pdf) of Advances in immune therapies in hematological malignancies

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Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC

Hasselblatt, Martin; Thomas, Christian; Federico, Aniello; Bens, Susanne et al.

Part of Neuropathology and Applied Neurobiology, 2022.

DOI for Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC Download full text (pdf) of Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC

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Scandiatransplant acceptable mismatch program-10 years with an effective strategy for transplanting highly sensitized patients.

Weinreich, Ilse; Bengtsson, Mats; Lauronen, Jouni; Naper, Christian et al.

Part of American Journal of Transplantation, 2022.

DOI for Scandiatransplant acceptable mismatch program-10 years with an effective strategy for transplanting highly sensitized patients.
The regulatory role of AP-2 beta in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential

Al-Sabri, Mohamed H.; Nikpour, Maryam; Clemensson, Laura Emily; Attwood, Misty M. et al.

Part of Cell & Bioscience, 2022.

DOI for The regulatory role of AP-2 beta in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential Download full text (pdf) of The regulatory role of AP-2 beta in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential

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Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets

Golec, Ewelina; Ekstrom, Alexander; Noga, Maciej; Omar-Hmeadi, Muhmmad et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2022.

DOI for Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets Download full text (pdf) of Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets

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Patient specific deep learning based segmentation for magnetic resonance guided prostate radiotherapy

Fransson, Samuel; Tilly, David; Strand, Robin

Part of Physics and Imaging in Radiation Oncology, p. 38-42, 2022.

DOI for Patient specific deep learning based segmentation for magnetic resonance guided prostate radiotherapy Download full text (pdf) of Patient specific deep learning based segmentation for magnetic resonance guided prostate radiotherapy

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DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma

Olsen, Thale Kristin; Dyberg, Cecilia; Embaie, Bethel Tesfai; Alchahin, Adele et al.

Part of JCI Insight, 2022.

DOI for DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma Download full text (pdf) of DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma

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Surgery for acute cholecystitis in severely comorbid patients: a population-based study on acute cholecystitis

Osterman, Erik; Helenius, Louise; Larsson, Christina; Jakobsson, Sofia et al.

Part of BMC Gastroenterology, 2022.

DOI for Surgery for acute cholecystitis in severely comorbid patients: a population-based study on acute cholecystitis Download full text (pdf) of Surgery for acute cholecystitis in severely comorbid patients: a population-based study on acute cholecystitis

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A method for Boolean analysis of protein interactions at a molecular level

Raykova, Doroteya; Kermpatsou, Despoina; Malmqvist, Tony; Harrison, Philip J et al.

Part of Nature Communications, 2022.

DOI for A method for Boolean analysis of protein interactions at a molecular level Download full text (pdf) of A method for Boolean analysis of protein interactions at a molecular level

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Fast and accurate gene regulatory network inference by normalized least squares regression

Hillerton, Thomas; Secilmi, Deniz; Nelander, Sven; Sonnhammer, Erik L. L. et al.

Part of Bioinformatics, p. 2263-2268, 2022.

DOI for Fast and accurate gene regulatory network inference by normalized least squares regression Download full text (pdf) of Fast and accurate gene regulatory network inference by normalized least squares regression

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"Randomized phase II study of azacitidine +/- lenalidomide in higher-risk myelodysplastic syndromes and acute myeloid leukemia with a karyotype including Del(5q)"

Rasmussen, Bengt; Gohring, Gudrun; Bernard, Elsa; Nilsson, Lars et al.

Part of Leukemia, p. 1436-1439, 2022.

DOI for "Randomized phase II study of azacitidine +/- lenalidomide in higher-risk myelodysplastic syndromes and acute myeloid leukemia with a karyotype including Del(5q)" Download full text (pdf) of "Randomized phase II study of azacitidine +/- lenalidomide in higher-risk myelodysplastic syndromes and acute myeloid leukemia with a karyotype including Del(5q)"

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Overall survival of patients with metastatic breast cancer in Sweden: a nationwide study

Valachis, Antonis; Carlqvist, Peter; Ma, Yuanjun; Szilcz, Mate et al.

Part of British Journal of Cancer, p. 720-725, 2022.

DOI for Overall survival of patients with metastatic breast cancer in Sweden: a nationwide study Download full text (pdf) of Overall survival of patients with metastatic breast cancer in Sweden: a nationwide study

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A role for the nuclear receptor NR2F6 in peritoneal B cell homeostasis

Olson, William J.; Jakic, Bojana; Labi, Verena; Woelk, Johannes et al.

Part of Frontiers in Immunology, 2022.

DOI for A role for the nuclear receptor NR2F6 in peritoneal B cell homeostasis Download full text (pdf) of A role for the nuclear receptor NR2F6 in peritoneal B cell homeostasis

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Benchmarking ultra-high molecular weight DNA preservation methods for long-read and long-range sequencing

Dahn, Hollis A.; Mountcastle, Jacquelyn; Balacco, Jennifer; Winkler, Sylke et al.

Part of GigaScience, 2022.

DOI for Benchmarking ultra-high molecular weight DNA preservation methods for long-read and long-range sequencing Download full text (pdf) of Benchmarking ultra-high molecular weight DNA preservation methods for long-read and long-range sequencing

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Quartz Crystal Microbalance Measurement of Histidine-Rich Glycoprotein and Stanniocalcin-2 Binding to Each Other and to Inflammatory Cells

Persson Skare, Tor; Kaito, Hiroshi; Durall, Claudia; Aastrup, Teodor et al.

Part of Cells, 2022.

DOI for Quartz Crystal Microbalance Measurement of Histidine-Rich Glycoprotein and Stanniocalcin-2 Binding to Each Other and to Inflammatory Cells Download full text (pdf) of Quartz Crystal Microbalance Measurement of Histidine-Rich Glycoprotein and Stanniocalcin-2 Binding to Each Other and to Inflammatory Cells

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Identifying patients with chronic lymphocytic leukemia without need of treatment: End of endless watch and wait?

Brieghel, Christian; Galle, Veerle; Agius, Rudi; Da Cunha-Bang, Caspar et al.

Part of European Journal of Haematology, p. 369-378, 2022.

DOI for Identifying patients with chronic lymphocytic leukemia without need of treatment: End of endless watch and wait? Download full text (pdf) of Identifying patients with chronic lymphocytic leukemia without need of treatment: End of endless watch and wait?

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Hormonal contraception and risk of breast cancer and breast cancer in situ among Swedish women 15-34 years of age: A nationwide register-based study

Niemeyer Hultstrand, Jenny; Gemzell-Danielsson, Kristina; Kallner, Helena Kopp; Lindman, Henrik et al.

Part of The Lancet Regional Health, 2022.

DOI for Hormonal contraception and risk of breast cancer and breast cancer in situ among Swedish women 15-34 years of age: A nationwide register-based study Download full text (pdf) of Hormonal contraception and risk of breast cancer and breast cancer in situ among Swedish women 15-34 years of age: A nationwide register-based study

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How persons with systemic mastocytosis describe the time between symptom onset and receiving diagnosis

Hamberg Levedahl, Kerstin; Nilsson, Annika; Johansson, Birgitta; Hedström, Mariann

Part of Primary Health Care Research and Development, 2022.

DOI for How persons with systemic mastocytosis describe the time between symptom onset and receiving diagnosis Download full text (pdf) of How persons with systemic mastocytosis describe the time between symptom onset and receiving diagnosis

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Loss of Nexilin function leads to a recessive lethal fetal cardiomyopathy characterized by cardiomegaly and endocardial fibroelastosis

Johansson, Josefin; Frykholm, Carina; Ericson, Katharina; Kazamia, Kalliopi et al.

Part of American Journal of Medical Genetics. Part A, p. 1676-1687, 2022.

DOI for Loss of Nexilin function leads to a recessive lethal fetal cardiomyopathy characterized by cardiomegaly and endocardial fibroelastosis Download full text (pdf) of Loss of Nexilin function leads to a recessive lethal fetal cardiomyopathy characterized by cardiomegaly and endocardial fibroelastosis

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Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases

Lundtoft, Christian; Pucholt, Pascal; Martin, Myriam; Bianchi, Matteo et al.

Part of Arthritis & Rheumatology, p. 1440-1450, 2022.

DOI for Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases Download full text (pdf) of Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases

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Reply to Assoc. Prof. Kocak: ARTICLE COMMENTARIES: CLINICAL ONCOLOGY

Willén, Linda; Berglund, Anders; Bergström, Stefan; Isaksson, Johan et al.

Part of Acta Oncologica, p. 320-320, 2022.

DOI for Reply to Assoc. Prof. Kocak: ARTICLE COMMENTARIES: CLINICAL ONCOLOGY
Distribution of E- and N-cadherin in subgroups of non-functioning pituitary neuroendocrine tumours

Oystese, Kristin Astrid B.; Casar Borota, Olivera; Berg-Johnsen, Jon; Berg, Jens Petter et al.

Part of Endocrine (Basingstoke), p. 151-159, 2022.

DOI for Distribution of E- and N-cadherin in subgroups of non-functioning pituitary neuroendocrine tumours Download full text (pdf) of Distribution of E- and N-cadherin in subgroups of non-functioning pituitary neuroendocrine tumours

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The genomic architecture of the passerine MHC region: High repeat content and contrasting evolutionary histories of single copy and tandemly duplicated MHC genes

Westerdahl, Helena; Mellinger, Samantha; Sigeman, Hanna; Kutschera, Verena E. et al.

Part of Molecular Ecology Resources, p. 2379-2395, 2022.

DOI for The genomic architecture of the passerine MHC region: High repeat content and contrasting evolutionary histories of single copy and tandemly duplicated MHC genes Download full text (pdf) of The genomic architecture of the passerine MHC region: High repeat content and contrasting evolutionary histories of single copy and tandemly duplicated MHC genes

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Glioblastoma CD105(+) cells define a SOX2(-) cancer stem cell-like subpopulation in the pre-invasive niche

Li, Jiaxin; Ek, Fredrik; Olsson, Roger; Belting, Mattias et al.

Part of Acta neuropathologica communications, 2022.

DOI for Glioblastoma CD105(+) cells define a SOX2(-) cancer stem cell-like subpopulation in the pre-invasive niche Download full text (pdf) of Glioblastoma CD105(+) cells define a SOX2(-) cancer stem cell-like subpopulation in the pre-invasive niche

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An Adaptable Antibody-Based Platform for Flexible Synthetic Peptide Delivery Built on Agonistic CD40 Antibodies

Eltahir, Mohamed; Lauren, Ida; Lord, Martin; Chourlia, Aikaterini et al.

Part of Advanced Therapeutics, 2022.

DOI for An Adaptable Antibody-Based Platform for Flexible Synthetic Peptide Delivery Built on Agonistic CD40 Antibodies Download full text (pdf) of An Adaptable Antibody-Based Platform for Flexible Synthetic Peptide Delivery Built on Agonistic CD40 Antibodies

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Precision radiation of immune checkpoint therapy resistant melanoma metastases (PROMMEL study): study protocol for a phase II open-label multicenter trial

Backlund, Ellen; Yang, Muyi; Grozman, Vitali; Masucci, Giuseppe et al.

Part of Acta Oncologica, p. 869-873, 2022.

DOI for Precision radiation of immune checkpoint therapy resistant melanoma metastases (PROMMEL study): study protocol for a phase II open-label multicenter trial
Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19

Hultström, Michael; Frithiof, Robert; Grip, Jonathan; Lindelöf, Linnea et al.

Part of Nature Immunology, p. 861-864, 2022.

DOI for Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19
Experimental HER2-Targeted Therapy Using ADAPT6-ABD-mcDM1 in Mice Bearing SKOV3 Ovarian Cancer Xenografts: Efficacy and Selection of Companion Imaging Counterpart

Garousi, Javad; Xu, Tianqi; Liu, Yongsheng; Vorontsova, Olga et al.

Part of Pharmaceutics, 2022.

DOI for Experimental HER2-Targeted Therapy Using ADAPT6-ABD-mcDM1 in Mice Bearing SKOV3 Ovarian Cancer Xenografts: Efficacy and Selection of Companion Imaging Counterpart Download full text (pdf) of Experimental HER2-Targeted Therapy Using ADAPT6-ABD-mcDM1 in Mice Bearing SKOV3 Ovarian Cancer Xenografts: Efficacy and Selection of Companion Imaging Counterpart

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Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion

Papadakos, Konstantinos S.; Lundgren, Sebastian; Gialeli, Chrysostomi; Micke, Patrick et al.

Part of Oncoimmunology, 2022.

DOI for Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion Download full text (pdf) of Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion

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Complement C3 inhibition in severe COVID-19 using compstatin AMY-101

Skendros, Panagiotis; Germanidis, Georgios; Mastellos, Dimitrios C.; Antoniadou, Christina et al.

Part of Science Advances, 2022.

DOI for Complement C3 inhibition in severe COVID-19 using compstatin AMY-101 Download full text (pdf) of Complement C3 inhibition in severe COVID-19 using compstatin AMY-101

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CD44 Depletion in Glioblastoma Cells Suppresses Growth and Stemness and Induces Senescence

Kolliopoulos, Constantinos; Ali, Mohamad Moustafa; Castillejo-Lopez, Casimiro; Heldin, Carl-Henrik et al.

Part of Cancers, 2022.

DOI for CD44 Depletion in Glioblastoma Cells Suppresses Growth and Stemness and Induces Senescence Download full text (pdf) of CD44 Depletion in Glioblastoma Cells Suppresses Growth and Stemness and Induces Senescence

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RNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer

Staaf, Johan; Häkkinen, Jari; Hegardt, Cecilia; Saal, Lao H. et al.

Part of npj Breast Cancer, 2022.

DOI for RNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer Download full text (pdf) of RNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer

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Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression

Korhonen, Emilia A.; Murtomäki, Aino; Jha, Sawan Kumar; Anisimov, Andrey et al.

Part of Journal of Clinical Investigation, 2022.

DOI for Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression Download full text (pdf) of Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression

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PDGFR beta(+) cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny

da Bandeira, Diana Sa; Kilpatrick, Alastair Morris; Marques, Madalena; Gomez-Salazar, Mario et al.

Part of Cell reports, 2022.

DOI for PDGFR beta(+) cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny Download full text (pdf) of PDGFR beta(+) cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny

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Hospital factors and metastatic surgery in colorectal cancer patients, a population-based cohort study

Ljunggren, Malin; Weibull, Caroline E.; Rosander, Emma; Palmer, Gabriella et al.

Part of BMC Cancer, 2022.

DOI for Hospital factors and metastatic surgery in colorectal cancer patients, a population-based cohort study Download full text (pdf) of Hospital factors and metastatic surgery in colorectal cancer patients, a population-based cohort study

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NOX4 regulates TGF beta-induced proliferation and self-renewal in glioblastoma stem cells

Garcia-Gomez, Pedro; Golan, Irene; Dadras, Mahsa Shahidi; Mezheyeuski, Artur et al.

Part of Molecular Oncology, p. 1891-1912, 2022.

DOI for NOX4 regulates TGF beta-induced proliferation and self-renewal in glioblastoma stem cells Download full text (pdf) of NOX4 regulates TGF beta-induced proliferation and self-renewal in glioblastoma stem cells

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Islet Gene View-a tool to facilitate islet research

Asplund, Olof; Storm, Petter; Chandra, Vikash; Hatem, Gad et al.

Part of Life Science Alliance, 2022.

DOI for Islet Gene View-a tool to facilitate islet research Download full text (pdf) of Islet Gene View-a tool to facilitate islet research

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High-Throughput immunogenetics for precision medicine in cancer

Agathangelidis, Andreas; Vlachonikola, Elisavet; Davi, Frederic; Langerak, Anton W. et al.

Part of Seminars in Cancer Biology, p. 80-88, 2022.

DOI for High-Throughput immunogenetics for precision medicine in cancer Download full text (pdf) of High-Throughput immunogenetics for precision medicine in cancer

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CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers

Jin, Chuan; Ma, Jing; Ramachandran, Mohanraj; Yu, Di et al.

Part of Nature Biomedical Engineering, p. 830-841, 2022.

DOI for CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers Download full text (pdf) of CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers

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Complement activation prior to symptom onset in myeloperoxidase ANCA-associated vasculitis but not proteinase 3 ANCA associated vasculitis-A Swedish biobank study

Johansson, L.; Berglin, E.; Eriksson, Oskar; Mohammad, A. J. et al.

Part of Scandinavian Journal of Rheumatology, p. 214-219, 2022.

DOI for Complement activation prior to symptom onset in myeloperoxidase ANCA-associated vasculitis but not proteinase 3 ANCA associated vasculitis-A Swedish biobank study Download full text (pdf) of Complement activation prior to symptom onset in myeloperoxidase ANCA-associated vasculitis but not proteinase 3 ANCA associated vasculitis-A Swedish biobank study

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A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats

Tegehall, Angelica; Ingvast, Sofie; Melhus, Åsa; Skog, Oskar et al.

Part of Acta Diabetologica, p. 1011-1018, 2022.

DOI for A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats Download full text (pdf) of A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats

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Outcome in PCNSL patients and its association with PD-L1+leukocytes in the tumor microenvironment

Abdulla, Maysaa; Hollander, Peter; Lindskog, Cecilia; Sundström, Christer et al.

Part of Acta Oncologica, p. 824-829, 2022.

DOI for Outcome in PCNSL patients and its association with PD-L1+leukocytes in the tumor microenvironment
Cardiovascular disease in patients with chronic lymphocytic leukemia: A Swedish nationwide register study with matched comparators

Larsson, Karin; Soderling, Jonas; Höglund, Martin; Glimelius, Ingrid et al.

Part of American Journal of Hematology, p. E255-E257, 2022.

DOI for Cardiovascular disease in patients with chronic lymphocytic leukemia: A Swedish nationwide register study with matched comparators
PTEN inhibits AMPK to control collective migration

Peglion, Florent; Capuana, Lavinia; Perfettini, Isabelle; Boucontet, Laurent et al.

Part of Nature Communications, 2022.

DOI for PTEN inhibits AMPK to control collective migration Download full text (pdf) of PTEN inhibits AMPK to control collective migration

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Chemotherapeutic Activities of Dietary Phytoestrogens against Prostate Cancer: From Observational to Clinical Studies

Sohel, Md; Sultana, Habiba; Sultana, Tayeba; Al Mamun, Abdullah et al.

Part of Current pharmaceutical design, p. 1561-1580, 2022.

DOI for Chemotherapeutic Activities of Dietary Phytoestrogens against Prostate Cancer: From Observational to Clinical Studies
A human adipose tissue cell-type transcriptome atlas

Norreen-Thorsen, Marthe; Struck, Eike Christopher; Oling, Sofia; Zwahlen, Martin et al.

Part of Cell reports, 2022.

DOI for A human adipose tissue cell-type transcriptome atlas Download full text (pdf) of A human adipose tissue cell-type transcriptome atlas

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Oral Contraceptives, Hormone Replacement Therapy, and Stroke Risk

Johansson, Therese; Fowler, Philip; Ek, Weronica E.; Karlsson, Torgny et al.

Part of Stroke, 2022.

DOI for Oral Contraceptives, Hormone Replacement Therapy, and Stroke Risk

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Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation

Gerogianni, Alexandra; Dimitrov, Jordan D.; Zarantonello, Alessandra; Poillerat, Victoria et al.

Part of Frontiers in Immunology, 2022.

DOI for Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation Download full text (pdf) of Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation

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Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow

Orlich, Michael M.; Dieguez-Hurtado, Rodrigo; Muehlfriedel, Regine; Sothilingam, Vithiyanjali et al.

Part of Circulation Research, p. 308-327, 2022.

DOI for Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow Download full text (pdf) of Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow

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CD49b identifies functionally and epigenetically distinct subsets of lineage-biased hematopoietic stem cells

Somuncular, Ece; Hauenstein, Julia; Khalkar, Prajakta; Johansson, Anne-Sofie et al.

Part of Stem Cell Reports, p. 1546-1560, 2022.

DOI for CD49b identifies functionally and epigenetically distinct subsets of lineage-biased hematopoietic stem cells Download full text (pdf) of CD49b identifies functionally and epigenetically distinct subsets of lineage-biased hematopoietic stem cells

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Autoantibodies Associated with Autoimmune Liver Diseases in a Healthy Population: Evaluation of a Commercial Immunoblot Test

Ahmad, Awais; Dahle, Charlotte; Rönnelid, Johan; Sjowall, Christopher et al.

Part of Diagnostics, 2022.

DOI for Autoantibodies Associated with Autoimmune Liver Diseases in a Healthy Population: Evaluation of a Commercial Immunoblot Test Download full text (pdf) of Autoantibodies Associated with Autoimmune Liver Diseases in a Healthy Population: Evaluation of a Commercial Immunoblot Test

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Regeneration in the Auditory Organ in Cuban and African Dwarf Crocodiles (Crocodylus rhombifer and Osteolaemus tetraspis) Can We Learn From the Crocodile How to Restore Our Hearing?

Li, Hao; Staxäng, Karin; Hodik, Monika; Melkersson, Karl-Gunnar et al.

Part of Frontiers in Cell and Developmental Biology, 2022.

DOI for Regeneration in the Auditory Organ in Cuban and African Dwarf Crocodiles (Crocodylus rhombifer and Osteolaemus tetraspis) Can We Learn From the Crocodile How to Restore Our Hearing? Download full text (pdf) of Regeneration in the Auditory Organ in Cuban and African Dwarf Crocodiles (Crocodylus rhombifer and Osteolaemus tetraspis) Can We Learn From the Crocodile How to Restore Our Hearing?

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Plasma protein biomarker profiling reveals major differences between acute leukaemia, lymphoma patients and controls

Sabaa, Amal Abu; Shen, Qiujin; Lennmyr, Emma; Enblad, Anna Pia et al.

Part of New Biotechnology, p. 21-29, 2022.

DOI for Plasma protein biomarker profiling reveals major differences between acute leukaemia, lymphoma patients and controls Download full text (pdf) of Plasma protein biomarker profiling reveals major differences between acute leukaemia, lymphoma patients and controls

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Preclinical Evaluation of a New Format of Ga-68- and In-111-Labeled Affibody Molecule Z(IGF-1R:4551) for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT

Liu, Yongsheng; Yu, Shengze; Xu, Tianqi; Bodenko, Vitalina et al.

Part of Pharmaceutics, 2022.

DOI for Preclinical Evaluation of a New Format of Ga-68- and In-111-Labeled Affibody Molecule Z(IGF-1R:4551) for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT Download full text (pdf) of Preclinical Evaluation of a New Format of Ga-68- and In-111-Labeled Affibody Molecule Z(IGF-1R:4551) for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT

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Acute healthcare utilization in end-of-life among Swedish brain tumor patients - a population based register study

Lindskog, Magnus; Schultz, Torbjorn; Strang, Peter

Part of BMC Palliative Care, 2022.

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Variation of Complement Protein Levels in Maternal Plasma and Umbilical Cord Blood during Normal Pregnancy: An Observational Study

Saleh, Muna; Compagno, Michele; Pihl, Sofia; Strevens, Helena et al.

Part of Journal of Clinical Medicine, 2022.

DOI for Variation of Complement Protein Levels in Maternal Plasma and Umbilical Cord Blood during Normal Pregnancy: An Observational Study Download full text (pdf) of Variation of Complement Protein Levels in Maternal Plasma and Umbilical Cord Blood during Normal Pregnancy: An Observational Study

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Investigating the Effect of Estradiol Levels on the Risk of Breast, Endometrial, and Ovarian Cancer

Johansson, Åsa; Schmitz, Daniel; Höglund, Julia; Hadizadeh, Fatemeh et al.

Part of Journal of the Endocrine Society, 2022.

DOI for Investigating the Effect of Estradiol Levels on the Risk of Breast, Endometrial, and Ovarian Cancer Download full text (pdf) of Investigating the Effect of Estradiol Levels on the Risk of Breast, Endometrial, and Ovarian Cancer

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Affibody-Mediated PNA-Based Pretargeted Cotreatment Improves Survival of Trastuzumab-Treated Mice Bearing HER2-Expressing Xenografts

Oroujeni, Maryam; Tano, Hanna; Vorobyeva, Anzhelika; Liu, Yongsheng et al.

Part of Journal of Nuclear Medicine, p. 1046-1051, 2022.

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mafba and mafbb differentially regulate lymphatic endothelial cell migration in topographically distinct manners

Arnold, Hannah; Panara, Virginia; Hussmann, Melina; Gorniok, Beata Filipek et al.

Part of Cell reports, 2022.

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Single-cell transcriptional pharmacodynamics of trifluridine in a tumor-immune model

Selvin, Tove; Fasterius, Erik; Jarvius, Malin; Fryknäs, Mårten et al.

Part of Scientific Reports, 2022.

DOI for Single-cell transcriptional pharmacodynamics of trifluridine in a tumor-immune model Download full text (pdf) of Single-cell transcriptional pharmacodynamics of trifluridine in a tumor-immune model

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Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response

Jin, Chuan; Ali, Arwa; Iskantar, Alexandros; Fotaki, Grammatiki et al.

Part of Oncoimmunology, 2022.

DOI for Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response Download full text (pdf) of Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response

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Migrating to Long-Read Sequencing for Clinical Routine BCR-ABL1 TKI Resistance Mutation Screening

Schaal, Wesley; Ameur, Adam; Olsson-Strömberg, Ulla; Hermansson, Monica et al.

Part of Cancer Informatics, p. 1-8, 2022.

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Impact of autoimmune serology test results on RA classification and diagnosis

Van Hoovels, Lieve; Studenic, Paul; Sieghart, Daniela; Steiner, Günter et al.

Part of Journal of Translational Autoimmunity, 2022.

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KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling

Ando, Koji; Tong, Lei; Peng, Di; Vazquez-Liebanas, Elisa et al.

Part of Developmental Cell, p. 1383-1399.e7, 2022.

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ADAMTS18⁺ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels

Bernier-Latmani, Jeremiah; Mauri, Cristina; Marcone, Rachel; Renevey, Francois et al.

Part of Nature Communications, 2022.

DOI for ADAMTS18⁺ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels Download full text (pdf) of ADAMTS18⁺ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels

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Iron Chelator VLX600 Inhibits Mitochondrial Respiration and Promotes Sensitization of Neuroblastoma Cells in Nutrition-Restricted Conditions

Westergren Jakobsson, Amanda; Kundu, Snehangshu; Guo, Jing; Chowdhury, Azazul Islam et al.

Part of Cancers, 2022.

DOI for Iron Chelator VLX600 Inhibits Mitochondrial Respiration and Promotes Sensitization of Neuroblastoma Cells in Nutrition-Restricted Conditions Download full text (pdf) of Iron Chelator VLX600 Inhibits Mitochondrial Respiration and Promotes Sensitization of Neuroblastoma Cells in Nutrition-Restricted Conditions

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Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules

Rinne, Sara S.; Yin, Wen; Borras, Anna Mestre; Abouzayed, Ayman et al.

Part of Biomedicines, 2022.

DOI for Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules Download full text (pdf) of Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules

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Range-shifter effects on the stray field in proton therapy measured with the variance–covariance method

Eliasson, Linda; Lillhök, Jan; Bäck, Torbjörn; Billnert-Maróti, Robert et al.

Part of Frontiers in Oncology, 2022.

DOI for Range-shifter effects on the stray field in proton therapy measured with the variance–covariance method Download full text (pdf) of Range-shifter effects on the stray field in proton therapy measured with the variance–covariance method

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Prolonged deprivation of arginine or leucine induces PI3K/ Akt-dependent reactivation of mTORC1

Buel, Gwen R.; Dang, Huy Q.; Asara, John M.; Blenis, John et al.

Part of Journal of Biological Chemistry, 2022.

DOI for Prolonged deprivation of arginine or leucine induces PI3K/ Akt-dependent reactivation of mTORC1 Download full text (pdf) of Prolonged deprivation of arginine or leucine induces PI3K/ Akt-dependent reactivation of mTORC1

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A murine model of cerebral cavernous malformations with acute hemorrhage

Maderna, Claudio; Pisati, Federica; Tripodo, Claudio; Dejana, Elisabetta et al.

Part of iScience, 2022.

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Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality

Sano, Soichi; Horitani, Keita; Ogawa, Hayato; Halvardson, Jonatan et al.

Part of Science, p. 292-297, 2022.

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Cellular Origin of Sporadic CCMs

Betsholtz, Christer; Gängel, Konstantin; Mäkinen, Taija

Part of New England Journal of Medicine, p. 1291-1291, 2022.

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Limited benefit in patients with MDS receiving venetoclax and azacitidine as a bridge to allogeneic stem cell transplantation

Jadersten, Martin; Boriskina, Ksenia; Lindholm, Carolin; Weström, Simone et al.

Part of Leukemia and Lymphoma, p. 755-758, 2022.

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International Forum on Home-Based Blood Transfusion: Responses

Shaw, Briony; Wood, Erica; McQuilten, Zoe; Callum, Jeannie et al.

Part of Vox Sanguinis, p. E44-E57, 2022.

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Inflammation and neutrophil extracellular traps in cerebral cavernous malformation (vol 79, 206, 2022)

Yau, Anthony C. Y.; Globisch, Maria A.; Onyeogaziri, Favour; Conze, Lei L. et al.

Part of Cellular and Molecular Life Sciences (CMLS), 2022.

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Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level

Wang, Fei; Ding, Peiwen; Liang, Xue; Ding, Xiangning et al.

Part of Nature Communications, 2022.

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High prevalence of somatic PIK3CA and TP53 pathogenic variants in the normal mammary gland tissue of sporadic breast cancer patients revealed by duplex sequencing

Kostecka, Anna; Nowikiewicz, Tomasz; Olszewski, Pawel; Koczkowska, Magdalena et al.

Part of npj Breast Cancer, 2022.

DOI for High prevalence of somatic PIK3CA and TP53 pathogenic variants in the normal mammary gland tissue of sporadic breast cancer patients revealed by duplex sequencing Download full text (pdf) of High prevalence of somatic PIK3CA and TP53 pathogenic variants in the normal mammary gland tissue of sporadic breast cancer patients revealed by duplex sequencing

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LymphoTrack Is Equally Sensitive as PCR GeneScan and Sanger Sequencing for Detection of Clonal Rearrangements in ALL Patients

Paulsen, Karin; Marincevic, Millaray; Cavelier, Lucia; Hollander, Peter et al.

Part of Diagnostics, 2022.

DOI for LymphoTrack Is Equally Sensitive as PCR GeneScan and Sanger Sequencing for Detection of Clonal Rearrangements in ALL Patients Download full text (pdf) of LymphoTrack Is Equally Sensitive as PCR GeneScan and Sanger Sequencing for Detection of Clonal Rearrangements in ALL Patients

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Unexpected short- and long-term effects of chronic adolescent HU-210 exposure on emotional behavior

Farinha-Ferreira, Miguel; Rei, Nadia; Fonseca-Gomes, Joao; Miranda-Lourenco, Catarina et al.

Part of Neuropharmacology, 2022.

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Clonal haematopoiesis as a risk factor for therapy-related myeloid neoplasms in patients with chronic lymphocytic leukaemia treated with chemo-(immuno)therapy

Voso, Maria-Teresa; Pandzic, Tatjana; Falconi, Giulia; Dencic-Fekete, Marija et al.

Part of British Journal of Haematology, p. 103-113, 2022.

DOI for Clonal haematopoiesis as a risk factor for therapy-related myeloid neoplasms in patients with chronic lymphocytic leukaemia treated with chemo-(immuno)therapy
Late relapses in Hodgkin lymphoma - should we search for the needle in the haystack?

El-Galaly, Tarec Christoffer; Glimelius, Ingrid

Part of British Journal of Haematology, p. 11-13, 2022.

DOI for Late relapses in Hodgkin lymphoma - should we search for the needle in the haystack? Download full text (pdf) of Late relapses in Hodgkin lymphoma - should we search for the needle in the haystack?

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Survival in mantle cell lymphoma after frontline treatment with R-bendamustine, R-CHOP and the Nordic MCL2 regimen - a real world study on patients diagnosed in Sweden 2007-2017

Albertsson-Lindblad, Alexandra; Palsdottir, Thorgerdur; Smedby, Karin E.; Weibull, Caroline E. et al.

Part of Haematologica, p. 740-743, 2022.

DOI for Survival in mantle cell lymphoma after frontline treatment with R-bendamustine, R-CHOP and the Nordic MCL2 regimen - a real world study on patients diagnosed in Sweden 2007-2017
Distribution of five clinically important neuroglial proteins in the human brain.

Sjölin, Karl; Kultima, Kim; larsson, Anders; Freyhult, Eva et al.

Part of Molecular brain, 2022.

DOI for Distribution of five clinically important neuroglial proteins in the human brain. Download full text (pdf) of Distribution of five clinically important neuroglial proteins in the human brain.

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Phase I Clinical Trial Using [Tc-99m]Tc-1-thio-D-glucose for Diagnosis of Lymphoma Patients

Chernov, Vladimir; Dudnikova, Ekaterina; Zelchan, Roman; Medvedeva, Anna et al.

Part of Pharmaceutics, 2022.

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Secondary resistance to idelalisib is characterized by upregulation of IGF1R rather than by MAPK/ERK pathway mutations

Tausch, Eugen; Ljungström, Viktor; Agathangelidis, Andreas; Zapatka, Marc et al.

Part of Blood, p. 3340-3344, 2022.

DOI for Secondary resistance to idelalisib is characterized by upregulation of IGF1R rather than by MAPK/ERK pathway mutations
Identification, discrimination and heterogeneity of fibroblasts

Lendahl, Urban; Muhl, Lars; Betsholtz, Christer

Part of Nature Communications, 2022.

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Caspase-2 is a mediator of apoptotic signaling in response to gemtuzumab ozogamicin in acute myeloid leukemia

Haag, Petra; Olsson, Magnus; Forsberg, Jeremy; Lindberg, Marita Lagergren et al.

Part of Cell Death Discovery, 2022.

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Real World Evaluation of the Prosigna/PAM50 Test in a Node-Negative Postmenopausal Swedish Population: A Multicenter Study

Kjallquist, Una; Acs, Balazs; Margolin, Sara; Karlsson, Emelie et al.

Part of Cancers, 2022.

DOI for Real World Evaluation of the Prosigna/PAM50 Test in a Node-Negative Postmenopausal Swedish Population: A Multicenter Study Download full text (pdf) of Real World Evaluation of the Prosigna/PAM50 Test in a Node-Negative Postmenopausal Swedish Population: A Multicenter Study

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Last modified: 2022-09-07