Publications in DiVA – Anna Dimberg

CD93 maintains endothelial barrier function by limiting the phosphorylation and turnover of VE-cadherin

Lugano, Roberta; Vemuri, Kalyani; Barbera, Stefano; Orlandini, Maurizio et al.

Part of The FASEB Journal, 2023.

DOI for CD93 maintains endothelial barrier function by limiting the phosphorylation and turnover of VE-cadherin Download full text (pdf) of CD93 maintains endothelial barrier function by limiting the phosphorylation and turnover of VE-cadherin

Complementarity-determining region clustering may cause CAR-T cell dysfunction

Sarén, Tina; Saronio, Giulia; Marti Torrell, Paula; Zhu, Xu et al.

Part of Nature Communications, 2023.

DOI for Complementarity-determining region clustering may cause CAR-T cell dysfunction Download full text (pdf) of Complementarity-determining region clustering may cause CAR-T cell dysfunction

Dimerization of the C-type lectin-like receptor CD93 promotes its binding to Multimerin-2 in endothelial cells

Barbera, Stefano; Raucci, Luisa; Tassone, Giusy; Tinti, Laura et al.

Part of International Journal of Biological Macromolecules, p. 453-464, 2023.

DOI for Dimerization of the C-type lectin-like receptor CD93 promotes its binding to Multimerin-2 in endothelial cells Download full text (pdf) of Dimerization of the C-type lectin-like receptor CD93 promotes its binding to Multimerin-2 in endothelial cells

Editorial: The blood-brain barrier in brain tumors: molecular mechanisms and therapeutic strategies

Zhang, Lei; Dimberg, Anna; Rasouli, Javad

Part of Frontiers in Neurology, 2023.

DOI for Editorial: The blood-brain barrier in brain tumors: molecular mechanisms and therapeutic strategies Download full text (pdf) of Editorial: The blood-brain barrier in brain tumors: molecular mechanisms and therapeutic strategies

Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Ramachandran, Mohanraj; Vaccaro, Alessandra; van de Walle, Tiarne; Georganaki, Maria et al.

Part of Cancer Cell, p. 1134-1151, 2023.

DOI for Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma Download full text (pdf) of Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Wnt signaling regulates MFSD2A-dependent drug delivery through endothelial transcytosis in glioma

Xie, Yuan; He, Liqun; Zhang, Yanyu; Huang, Hua et al.

Part of Neuro-Oncology, p. 1073-1084, 2023.

DOI for Wnt signaling regulates MFSD2A-dependent drug delivery through endothelial transcytosis in glioma

A method for Boolean analysis of protein interactions at a molecular level

Raykova, Doroteya; Kermpatsou, Despoina; Malmqvist, Tony; Harrison, Philip J et al.

Part of Nature Communications, 2022.

DOI for A method for Boolean analysis of protein interactions at a molecular level Download full text (pdf) of A method for Boolean analysis of protein interactions at a molecular level

Tertiary Lymphoid Structures: From Basic Biology to Translational Impact in Cancer. Editorial

Sautes-Fridman, Catherine; Dimberg, Anna; Verma, Vivek

Part of Frontiers in Immunology, 2022.

DOI for Tertiary Lymphoid Structures: From Basic Biology to Translational Impact in Cancer. Editorial Download full text (pdf) of Tertiary Lymphoid Structures: From Basic Biology to Translational Impact in Cancer. Editorial

Vaccination against galectin-1 promotes cytotoxic T-cell infiltration in melanoma and reduces tumor burden

Femel, Julia; van Hooren, Luuk; Herre, Melanie; Cedervall, Jessica et al.

Part of Cancer Immunology and Immunotherapy, p. 2029-2040, 2022.

DOI for Vaccination against galectin-1 promotes cytotoxic T-cell infiltration in melanoma and reduces tumor burden Download full text (pdf) of Vaccination against galectin-1 promotes cytotoxic T-cell infiltration in melanoma and reduces tumor burden

1p/19q co-deletion status is associated with distinct tumor-associated macrophage infiltration in IDH mutated lower-grade gliomas

Zhang, Yanyu; Xie, Yuan; He, Liqun; Tang, Jiefu et al.

Part of Cellular Oncology, p. 193-204, 2021.

DOI for 1p/19q co-deletion status is associated with distinct tumor-associated macrophage infiltration in IDH mutated lower-grade gliomas

Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma

van Hooren, Luuk; Vaccaro, Alessandra; Ramachandran, Mohanraj; Vazaios, Konstantinos et al.

Part of Nature Communications, 2021.

DOI for Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma Download full text (pdf) of Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma

Blockade of the CD93 pathway normalizes tumor vasculature to facilitate drug delivery and immunotherapy

Sun, Yi; Chen, Wei; Torphy, Robert J.; Yao, Sheng et al.

Part of Science Translational Medicine, 2021.

DOI for Blockade of the CD93 pathway normalizes tumor vasculature to facilitate drug delivery and immunotherapy

CD93 Signaling via Rho Proteins Drives Cytoskeletal Remodeling in Spreading Endothelial Cells

Barbera, Stefano; Raucci, Luisa; Lugano, Roberta; Tosi, Gian Marco et al.

Part of International Journal of Molecular Sciences, 2021.

DOI for CD93 Signaling via Rho Proteins Drives Cytoskeletal Remodeling in Spreading Endothelial Cells Download full text (pdf) of CD93 Signaling via Rho Proteins Drives Cytoskeletal Remodeling in Spreading Endothelial Cells

Deletions on Chromosome Y and Downregulation of the SRY Gene in Tumor Tissue Are Associated with Worse Survival of Glioblastoma Patients

Łysiak, Małgorzata; Smits, Anja; Roodakker, Kenney Roy; Sandberg, Elisabeth et al.

Part of Cancers, 2021.

DOI for Deletions on Chromosome Y and Downregulation of the SRY Gene in Tumor Tissue Are Associated with Worse Survival of Glioblastoma Patients Download full text (pdf) of Deletions on Chromosome Y and Downregulation of the SRY Gene in Tumor Tissue Are Associated with Worse Survival of Glioblastoma Patients

ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.

Huang, Hua; Georganaki, Maria; Conze, Lei Liu; Laviña, Bàrbara et al.

Part of Neuro-Oncology, p. 398-411, 2021.

DOI for ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma. Download full text (pdf) of ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.

IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma

Martikainen, Miika; Ramachandran, Mohanraj; Lugano, Roberta; Ma, Jing et al.

Part of MOLECULAR THERAPY-ONCOLYTICS, p. 37-46, 2021.

DOI for IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma Download full text (pdf) of IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma

Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing

Xie, Yuan; He, Liqun; Lugano, Roberta; Zhang, Yanyu et al.

Part of JCI Insight, 2021.

DOI for Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing Download full text (pdf) of Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing

The C-type lectin CD93 controls endothelial cell migration via activation of the Rho family of small GTPases

Barbera, Stefano; Lugano, Roberta; Pedalina, Alessia; Mongiat, Maurizio et al.

Part of Matrix Biology, p. 1-17, 2021.

DOI for The C-type lectin CD93 controls endothelial cell migration via activation of the Rho family of small GTPases

Fgfbp1 promotes blood-brain barrier development by regulating collagen IV deposition and maintaining Wnt/beta-catenin signaling

Cottarelli, Azzurra; Corada, Monica; Beznoussenko, Galina, V; Mironov, Alexander A. et al.

Part of Development, 2020.

DOI for Fgfbp1 promotes blood-brain barrier development by regulating collagen IV deposition and maintaining Wnt/beta-catenin signaling

Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis

Zhang, Yanyu; Cedervall, Jessica; Hamidi, Anahita; Herre, Melanie et al.

Part of Cancer Research, p. 3345-3358, 2020.

DOI for Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis

The Binding of CD93 to Multimerin-2 Promotes Choroidal Neovascularization

Tosi, Gian Marco; Neri, Giovanni; Barbera, Stefano; Mundo, Lucia et al.

Part of Investigative Ophthalmology and Visual Science, 2020.

DOI for The Binding of CD93 to Multimerin-2 Promotes Choroidal Neovascularization Download full text (pdf) of The Binding of CD93 to Multimerin-2 Promotes Choroidal Neovascularization

Tumor angiogenesis: causes, consequences, challenges and opportunities

Lugano, Roberta; Ramachandran, Mohanraj; Dimberg, Anna

Part of Cellular and Molecular Life Sciences (CMLS), p. 1745-1770, 2020.

DOI for Tumor angiogenesis: causes, consequences, challenges and opportunities Download full text (pdf) of Tumor angiogenesis: causes, consequences, challenges and opportunities

Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

Georganaki, Maria; Ramachandran, Mohanraj; Tuit, Sander; Nunez, Nicolas Gonzalo et al.

Part of Oncoimmunology, 2020.

DOI for Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy Download full text (pdf) of Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

Tumor endothelial ELTD1 as a predictive marker for treatment of renal cancer patients with sunitinib

Niinivirta, Marjut; Georganaki, Maria; Enblad, Gunilla; Lindskog, Cecilia et al.

Part of BMC Cancer, 2020.

DOI for Tumor endothelial ELTD1 as a predictive marker for treatment of renal cancer patients with sunitinib Download full text (pdf) of Tumor endothelial ELTD1 as a predictive marker for treatment of renal cancer patients with sunitinib

Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation

Arce, Maximiliano; Pinto, Mauricio P.; Galleguillos, Macarena; Munoz, Catalina et al.

Part of Cancers, 2019.

DOI for Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation Download full text (pdf) of Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation

Region-by-region analysis of PET, MRI, and histology in en bloc-resected oligodendrogliomas reveals intra-tumoral heterogeneity

Roodakker, Kenney Roy; Alhuseinalkhudhur, Ali; Al-Jaff, Mohammed; Georganaki, Maria et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. 569-579, 2019.

DOI for Region-by-region analysis of PET, MRI, and histology in en bloc-resected oligodendrogliomas reveals intra-tumoral heterogeneity

The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/1 integrin complex in endothelial cell adhesion and migration

Barbera, Stefano; Nardi, Federica; Elia, Ines; Realini, Giulia et al.

Part of Cell Communication and Signaling, 2019.

DOI for The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/1 integrin complex in endothelial cell adhesion and migration Download full text (pdf) of The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/1 integrin complex in endothelial cell adhesion and migration

Bones in human CYP26B1 deficiency and rats with hypervitaminosis A phenocopy Vegfa overexpression

Lind, Thomas; Lugano, Roberta; Gustafson, Ann-Marie; Norgård, Maria et al.

Part of Bone Reports, p. 27-36, 2018.

DOI for Bones in human CYP26B1 deficiency and rats with hypervitaminosis A phenocopy Vegfa overexpression Download full text (pdf) of Bones in human CYP26B1 deficiency and rats with hypervitaminosis A phenocopy Vegfa overexpression

CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis

Lugano, Roberta; Vemuri, Kalyani; Yu, Di; Bergqvist, Michael et al.

Part of Journal of Clinical Investigation, p. 3280-3297, 2018.

DOI for CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis Download full text (pdf) of CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis

Consensus guidelines for the use and interpretation of angiogenesis assays

Nowak-Sliwinska, Patrycja; Alitalo, Kari; Allen, Elizabeth; Anisimov, Andrey et al.

Part of Angiogenesis, p. 425-532, 2018.

DOI for Consensus guidelines for the use and interpretation of angiogenesis assays Download full text (pdf) of Consensus guidelines for the use and interpretation of angiogenesis assays

IDH mutation status is associated with distinct vascular gene expression signatures in lower-grade gliomas

Zhang, Lei; He, Liqun; Lugano, Roberta; Roodakker, Kenney Roy et al.

Part of Neuro-Oncology, p. 1505-1516, 2018.

DOI for IDH mutation status is associated with distinct vascular gene expression signatures in lower-grade gliomas Download full text (pdf) of IDH mutation status is associated with distinct vascular gene expression signatures in lower-grade gliomas

Osteoglycin - A switch from angiogenesis to T-cell recruitment?

Dimberg, Anna

Part of EBioMedicine, p. 22-23, 2018.

DOI for Osteoglycin - A switch from angiogenesis to T-cell recruitment? Download full text (pdf) of Osteoglycin - A switch from angiogenesis to T-cell recruitment?

Vascular Targeting to Increase the Efficiency of Immune Checkpoint Blockade in Cancer

Georganaki, Maria; van Hooren, Luuk; Dimberg, Anna

Part of Frontiers in Immunology, 2018.

DOI for Vascular Targeting to Increase the Efficiency of Immune Checkpoint Blockade in Cancer Download full text (pdf) of Vascular Targeting to Increase the Efficiency of Immune Checkpoint Blockade in Cancer

Activating CD40 While Inhibiting IL6R Induces Cytokine Production without PDL1 Upregulation in DCs

Eriksson, Emma; Milenova, Ioanna; Wenthe, Jessica; Moreno, Rafael et al.

Part of Molecular Therapy, p. 54-54, 2017.

Activation of myeloid and endothelial cells by CD40L gene therapy supports T-cell expansion and migration into the tumor microenvironment

Eriksson, Emma; Moreno, R; Milenova, I. Yoanna; Liljenfeldt, L et al.

Part of Gene Therapy, p. 92-103, 2017.

DOI for Activation of myeloid and endothelial cells by CD40L gene therapy supports T-cell expansion and migration into the tumor microenvironment Download full text (pdf) of Activation of myeloid and endothelial cells by CD40L gene therapy supports T-cell expansion and migration into the tumor microenvironment

Local checkpoint inhibition of CTLA-4 as a monotherapy or in combination with anti-PD1 prevents the growth of murine bladder cancer

van Hooren, Luuk; Sandin, Linda C.; Moskalev, Igor; Ellmark, Peter et al.

Part of European Journal of Immunology, p. 385-393, 2017.

DOI for Local checkpoint inhibition of CTLA-4 as a monotherapy or in combination with anti-PD1 prevents the growth of murine bladder cancer

Pharmacological targeting of peptidylarginine deiminase 4 prevents cancer-associated kidney injury in mice.

Cedervall, Jessica; Dragomir, Anca; Saupe, Falk; Zhang, Yanyu et al.

Part of Oncoimmunology, 2017.

DOI for Pharmacological targeting of peptidylarginine deiminase 4 prevents cancer-associated kidney injury in mice.

Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus

Ramachandran, Mohanraj; Yu, Di; Dyczynski, Matheus; Baskaran, Sathishkumar et al.

Part of Clinical Cancer Research, p. 1519-1530, 2017.

DOI for Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus

Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus.

Svensson, Emma; Milenova, Ioanna; Wenthe, Jessica; Ståhle, Magnus et al.

Part of Clinical Cancer Research, p. 5846-5857, 2017.

DOI for Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus.

The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells

Ramachandran, Mohanraj; Dimberg, Anna; Essand, Magnus

Part of Seminars in Cancer Biology, p. 23-35, 2017.

DOI for The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells Download full text (pdf) of The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells

ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer

Magnusson, Kristina; Gremel, Gabriela; Rydén, Lisa; Pontén, Victor et al.

Part of BMC Cancer, 2016.

DOI for ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer Download full text (pdf) of ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer

Heparanase Promotes Glioma Progression and is Inversely Correlated with Patient Survival.

Kundu, Soumi; Xiong, Anqi; Spyrou, Argyris; Wicher, Grzegorz et al.

Part of Molecular Cancer Research, p. 1243-1253, 2016.

DOI for Heparanase Promotes Glioma Progression and is Inversely Correlated with Patient Survival.

Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells

Zhang, Lei; Laaniste, Liisi; Jiang, Yiwen; Alafuzoff, Irina et al.

Part of OncoTarget, p. 80382-80390, 2016.

DOI for Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells Download full text (pdf) of Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells

Pleiotrophin is a driver of vascular abnormalization in glioblastoma

Zhang, Lei; Dimberg, Anna

Part of Molecular & Cellular Oncology, 2016.

DOI for Pleiotrophin is a driver of vascular abnormalization in glioblastoma

Sunitinib enhances the antitumor responses of agonistic CD40-antibody by reducing MDSCs and synergistically improving endothelial activation and T-cell recruitment

van Hooren, Luuk; Georganaki, Maria; Huang, Hua; Mangsbo, Sara M. et al.

Part of OncoTarget, p. 50277-50289, 2016.

DOI for Sunitinib enhances the antitumor responses of agonistic CD40-antibody by reducing MDSCs and synergistically improving endothelial activation and T-cell recruitment Download full text (pdf) of Sunitinib enhances the antitumor responses of agonistic CD40-antibody by reducing MDSCs and synergistically improving endothelial activation and T-cell recruitment

Tumor-induced neutrophil extracellular traps-drivers of systemic inflammation and vascular dysfunction

Cedervall, Jessica; Dimberg, Anna; Olsson, Anna-Karin

Part of Oncoimmunology, 2016.

DOI for Tumor-induced neutrophil extracellular traps-drivers of systemic inflammation and vascular dysfunction

Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Langenkamp, Elise; Zhang, Lei; Lugano, Roberta; Huang, Hua et al.

Part of Cancer Research, p. 4504-4516, 2015.

DOI for Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals

Cedervall, Jessica; Zhang, Yanyu; Huang, Hua; Zhang, Lei et al.

Part of Cancer Research, p. 2653-2662, 2015.

DOI for Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals

Next-Generation Pathology: Surveillance of Tumor Microecology

Koos, Björn; Kamali-Moghaddam, Masood; David, Leonor; Sobrinho-Simoes, Manuel et al.

Part of Journal of Molecular Biology, p. 2013-2022, 2015.

DOI for Next-Generation Pathology: Surveillance of Tumor Microecology

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Zhang, Lei; Kundu, Soumi; Feenstra, Tjerk; Li, Xiujuan et al.

Part of Science Signaling, 2015.

DOI for Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Tumor-Induced Local and Systemic Impact on Blood Vessel Function

Cedervall, Jessica; Dimberg, Anna; Olsson, Anna-Karin

Part of Mediators of Inflammation, 2015.

DOI for Tumor-Induced Local and Systemic Impact on Blood Vessel Function Download full text (pdf) of Tumor-Induced Local and Systemic Impact on Blood Vessel Function

VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through inhibition of NF-κB-induced endothelial activation

Huang, Hua; Langenkamp, Elise; Georganaki, Maria; Loskog, Angelica et al.

Part of The FASEB Journal, p. 227-238, 2015.

DOI for VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through inhibition of NF-κB-induced endothelial activation

CD40L gene therapy tilts the myeloid cell profile and promotes infiltration of activated T lymphocytes

Liljenfeldt, Lina; Dieterich, Lothar C.; Dimberg, Anna; Mangsbo, Sara M. et al.

Part of Cancer Gene Therapy, p. 95-102, 2014.

DOI for CD40L gene therapy tilts the myeloid cell profile and promotes infiltration of activated T lymphocytes

Progression of metastatic breast cancer can be attenuated by therapeutic vaccination against the tumor vascular marker ED-A

Femel, Julia; Huijbers, Elisabeth J. M.; Saupe, Falk; Cedervall, Jessica et al.

Part of Angiogenesis, p. 769-769, 2014.

Subtyping of gliomas of various WHO grades by the application of immunohistochemistry

Popova, Svetlana N; Bergqvist, Michael; Dimberg, Anna; Edqvist, Per-Henrik et al.

Part of Histopathology, p. 365-379, 2014.

DOI for Subtyping of gliomas of various WHO grades by the application of immunohistochemistry

The glioblastoma vasculature as a target for cancer therapy

Dimberg, Anna

Part of Biochemical Society Transactions, p. 1647-1652, 2014.

DOI for The glioblastoma vasculature as a target for cancer therapy

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer.

Femel, Julia; Huijbers, Elisabeth JM; Saupe, Falk; Cedervall, Jessica et al.

Part of OncoTarget, p. 12418-12427, 2014.

Download full text (pdf) of Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer.

alpha B-Crystallin regulates expansion of CD11b(+)Gr-1(+) immature myeloid cells during tumor progression

Dieterich, Lothar C; Schiller, Petter; Huang, Hua; Wawrousek, Eric F et al.

Part of The FASEB Journal, p. 151-162, 2013.

DOI for alpha B-Crystallin regulates expansion of CD11b(+)Gr-1(+) immature myeloid cells during tumor progression

alpha B-crystallin/HspB5 regulates endothelial-leukocyte interactions by enhancing NF-kappa B-induced up-regulation of adhesion molecules ICAM-1, VCAM-1 and E-selectin

Dieterich, Lothar C.; Huang, Hua; Massena, Sara; Golenhofen, Nikola et al.

Part of Angiogenesis, p. 975-983, 2013.

DOI for alpha B-crystallin/HspB5 regulates endothelial-leukocyte interactions by enhancing NF-kappa B-induced up-regulation of adhesion molecules ICAM-1, VCAM-1 and E-selectin Download full text (pdf) of alpha B-crystallin/HspB5 regulates endothelial-leukocyte interactions by enhancing NF-kappa B-induced up-regulation of adhesion molecules ICAM-1, VCAM-1 and E-selectin

VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

Hayashi, Makoto; Majumdar, Arindam; Li, Xiujuan; Adler, Jeremy et al.

Part of Nature Communications, p. 1672-, 2013.

DOI for VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

GABA-A Channel Subunit Expression in Human Glioma Correlates with Tumor Histology and Clinical Outcome

Smits, Anja; Jin, Zhe; Elsir, Tamador; Pedder, Hugo et al.

Part of PLOS ONE, p. e37041-, 2012.

DOI for GABA-A Channel Subunit Expression in Human Glioma Correlates with Tumor Histology and Clinical Outcome Download full text (pdf) of GABA-A Channel Subunit Expression in Human Glioma Correlates with Tumor Histology and Clinical Outcome

Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development

Wallgard, Elisabet; Nitzsche, Anja; Larsson, Jimmy; Guo, Xiaoyuan et al.

Part of Developmental Dynamics, p. 770-786, 2012.

DOI for Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development

Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma

Dimberg, Lina Y.; Dimberg, Anna; Ivarsson, Karolina; Fryknäs, Mårten et al.

Part of BMC Cancer, p. 318-, 2012.

DOI for Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma Download full text (pdf) of Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma

Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization

Dieterich, Lothar C.; Mellberg, Sofie; Langenkamp, Elise; Zhang, Lei et al.

Part of Journal of Pathology, p. 378-390, 2012.

DOI for Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization

Vascular endothelial growth factor receptor 2 (VEGFR-2) signalling activity in paediatric pilocytic astrocytoma is restricted to tumour endothelial cells

Sikkema, A. H.; de Bont, E. S. J. M.; Molema, G.; Dimberg, Anna et al.

Part of Neuropathology and Applied Neurobiology, p. 538-548, 2011.

DOI for Vascular endothelial growth factor receptor 2 (VEGFR-2) signalling activity in paediatric pilocytic astrocytoma is restricted to tumour endothelial cells

Chemokines in Angiogenesis

Dimberg, Anna

Part of Current Topics in Microbiology and Immunology, p. 59-80, 2010.

DOI for Chemokines in Angiogenesis

Activated platelets provide a functional microenvironment for the antiangiogenic fragment of histidine-rich glycoprotein

Thulin, Åsa; Ringvall, Maria; Dimberg, Anna; Kårehed, Karin et al.

Part of Molecular Cancer Research, p. 1792-1802, 2009.

DOI for Activated platelets provide a functional microenvironment for the antiangiogenic fragment of histidine-rich glycoprotein

Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis

Mellberg, Sofie; Dimberg, Anna; Bahram, Fuad; Hayashi, Makoto et al.

Part of The FASEB Journal, p. 1490-1502, 2009.

DOI for Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis

alphaB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis

Dimberg, Anna; Rylova, Svetlana; Dieterich, Lothar C; Olsson, Anna-Karin et al.

Part of Blood, p. 2015-2023, 2008.

DOI for alphaB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis

Ninein Is Expressed in the Cytoplasm of Angiogenic Tip-Cells and Regulates Tubular Morphogenesis of Endothelial Cells

Matsumoto, Taro; Schiller, Petter; Dietrich, Lothar C.; Bahram, Fuad et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 2123-2130, 2008.

DOI for Ninein Is Expressed in the Cytoplasm of Angiogenic Tip-Cells and Regulates Tubular Morphogenesis of Endothelial Cells

Endocan is a VEGF-A and PI3K regulated gene with increased expression in human renal cancer

Rennel, Emma; Mellberg, Sofie; Dimberg, Anna; Petersson, Ludvig et al.

Part of Experimental Cell Research, p. 1285-1294, 2007.

DOI for Endocan is a VEGF-A and PI3K regulated gene with increased expression in human renal cancer

FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin

Magnusson, Peetra U; Dimberg, Anna; Mellberg, Sofie; Lukinius, Agneta et al.

Part of Blood, p. 4214-4222, 2007.

DOI for FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin

IFN-gamma-induced upregulation of Fc gamma-receptor-I during activation of monocytic cells requires the PKR and NF kappa B pathways

Kårehed, Karin; Dimberg, Anna; Dahl, Staffan; Nilsson, Kenneth et al.

Part of Molecular Immunology, p. 615-624, 2007.

DOI for IFN-gamma-induced upregulation of Fc gamma-receptor-I during activation of monocytic cells requires the PKR and NF kappa B pathways

Lentiviral rescue of vascular endothelial growth factor receptor-2 expression in flk1-/- embryonic stem cells shows early priming of endothelial precursors

Li, Xiujuan; Edholm, Dan; Lanner, Fredrik; Breier, Georg et al.

Part of Stem Cells, p. 2987-2995, 2007.

DOI for Lentiviral rescue of vascular endothelial growth factor receptor-2 expression in flk1-/- embryonic stem cells shows early priming of endothelial precursors

Inhibition of monocytic differentiation by phosphorylation-deficient Stat1 is associated with impaired expression of Stat2, ICSBP/IRF8 and C/EBP epsilon

Dimberg, Anna; Kårehed, Karin; Nilsson, Kenneth; Öberg, Fredrik

Part of Scandinavian Journal of Immunology, p. 271-279, 2006.

DOI for Inhibition of monocytic differentiation by phosphorylation-deficient Stat1 is associated with impaired expression of Stat2, ICSBP/IRF8 and C/EBP epsilon

VEGF receptor signalling: in control of vascular function

Olsson, Anna-Karin; Dimberg, Anna; Kreuger, Johan; Claesson-Welsh, Lena

Part of Nature reviews. Molecular cell biology, p. 359-371, 2006.

DOI for VEGF receptor signalling: in control of vascular function

Ectopic and IFN-induced expression of Fas overcomes resistance to Fas-mediated apoptosis in multiple myeloma cells.

Dimberg, Lina; Dimberg, Anna; Ivarsson, Karolina; Strömberg, Thomas et al.

Part of Blood, 2005.

DOI for Ectopic and IFN-induced expression of Fas overcomes resistance to Fas-mediated apoptosis in multiple myeloma cells.

Fibroblast growth factor receptor-1 expression is required for hematopoietic but not endothelial cell development

Magnusson, Peetra Ulrica; Ronca, Roberto; Dell'Era, Patrizia; Carlstedt, Pia et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 944-949, 2005.

DOI for Fibroblast growth factor receptor-1 expression is required for hematopoietic but not endothelial cell development

Proteomic analysis of vascular endothelial growth factor-induced endothelial cell differentiation reveals a role for chloride intracellular channel 4 (CLIC4) in tubular morphogenesis.

Bohman, Svante; Matsumoto, Taro; Suh, Kwang; Dimberg, Anna et al.

Part of J Biol Chem, p. 42397-404, 2005.

VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis.

Matsumoto, Taro; Bohman, Svante; Dixelius, Johan; Berge, Tone et al.

Part of EMBO J, p. 2342-53, 2005.

Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone.

Strömberg, Thomas; Dimberg, Anna; Hammarberg, Anna; Carlson, Kristina et al.

Part of Blood, p. 3138-47, 2004.

Retinoic acid-induced cell cycle arrest of human myeloid cell lines.

Dimberg, A; Oberg, F

Part of Leuk Lymphoma, p. 1641-, 2003.

Ser727/Tyr701-phosphorylated Stat1 is required for the regulation ofc-Myc, cyclins, and p27Kip1 associated with ATRA-induced G0/G1 arrest ofU-937 cells.

Dimberg, A; Karlberg, I; Nilsson, K; Oberg, F

Part of Blood, p. 254-, 2003.

Retinoic acid-induced cell cycle arrest of human myeloid cell lines is associated with sequential down-regulation of c-Myc and cyclin E andposttranscriptional up-regulation of p27(Kip1).

Dimberg, A; Bahram, F; Karlberg, I; Larsson, LG et al.

Part of Blood, p. 2199-, 2002.

Phosphorylation-deficient Stat1 inhibits retinoic acid-induceddifferentiation and cell cycle arrest in U-937 monoblasts.

Dimberg, A; Nilsson, K; Oberg, F

Part of Blood, p. 2870-, 2000.

Stat1 involvement in retinoic acid induced differentiation of myeloid cells

Dimberg, Anna; Nilsson, Kenneth; Oberg, Fredrik

Part of Molecular mechanisms of signal transduction, p. 211-, 2000.