Publications in DiVA – Bo Nilsson

A Robust Method to Store Complement C3 With Superior Ability to Maintain the Native Structure and Function of the Protein

Adler, Anna; Manivel, Vivek Anand; Fromell, Karin; Teramura, Yuji et al.

Part of Frontiers in Immunology, 2022.

DOI for A Robust Method to Store Complement C3 With Superior Ability to Maintain the Native Structure and Function of the Protein Download full text (pdf) of A Robust Method to Store Complement C3 With Superior Ability to Maintain the Native Structure and Function of the Protein

Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation: A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients

Hultström, Michael; Fromell, Karin; Larsson, Anders; Persson, Barbro et al.

Part of Biomedicines, 2022.

DOI for Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation: A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients Download full text (pdf) of Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation: A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients

Blood compatibility of widely used central venous catheters; an experimental study

Thorarinsdottir, Hulda; Kander, Thomas; Johansson, Dorota; Nilsson, Bo et al.

Part of Scientific Reports, 2022.

DOI for Blood compatibility of widely used central venous catheters; an experimental study Download full text (pdf) of Blood compatibility of widely used central venous catheters; an experimental study

Complement C3 activation in the ICU: Disease and therapy as Bonnie and Clyde

Mannes, Marco; Mastellos, Dimitrios C.; Ekdahl, Kristina N.; Nilsson, Bo et al.

Part of Seminars in Immunology, 2022.

DOI for Complement C3 activation in the ICU: Disease and therapy as Bonnie and Clyde

Complement C3 inhibition in severe COVID-19 using compstatin AMY-101

Skendros, Panagiotis; Germanidis, Georgios; Mastellos, Dimitrios C.; Antoniadou, Christina et al.

Part of Science Advances, 2022.

DOI for Complement C3 inhibition in severe COVID-19 using compstatin AMY-101 Download full text (pdf) of Complement C3 inhibition in severe COVID-19 using compstatin AMY-101

Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases

Lundtoft, Christian; Pucholt, Pascal; Martin, Myriam; Bianchi, Matteo et al.

Part of Arthritis & Rheumatology, p. 1440-1450, 2022.

DOI for Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases Download full text (pdf) of Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases

Effect of liposome surface modification with water-soluble phospholipid polymer chain-conjugated lipids on interaction with human plasma proteins

Adler, Anna; Inoue, Yuuki; Nilsson Ekdahl, Kristina; Baba, Teruhiko et al.

Part of Journal of materials chemistry. B, p. 2512-2522, 2022.

DOI for Effect of liposome surface modification with water-soluble phospholipid polymer chain-conjugated lipids on interaction with human plasma proteins

Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19

Hultström, Michael; Frithiof, Robert; Grip, Jonathan; Lindelöf, Linnea et al.

Part of Nature Immunology, p. 861-864, 2022.

DOI for Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19

How the Innate Immune System of the Blood Contributes to Systemic Pathology in COVID-19-Induced ARDS and Provides Potential Targets for Treatment

Nilsson, Bo; Persson, Barbro; Eriksson, Oskar; Fromell, Karin et al.

Part of Frontiers in Immunology, 2022.

DOI for How the Innate Immune System of the Blood Contributes to Systemic Pathology in COVID-19-Induced ARDS and Provides Potential Targets for Treatment Download full text (pdf) of How the Innate Immune System of the Blood Contributes to Systemic Pathology in COVID-19-Induced ARDS and Provides Potential Targets for Treatment

Impact of spontaneous liposome modification with phospholipid polymer-lipid conjugates on protein interactions

Suzuki, Haruna; Adler, Anna; Huang, Tianwei; Kuramochi, Akiko et al.

Part of Science and Technology of Advanced Materials, p. 845-857, 2022.

DOI for Impact of spontaneous liposome modification with phospholipid polymer-lipid conjugates on protein interactions Download full text (pdf) of Impact of spontaneous liposome modification with phospholipid polymer-lipid conjugates on protein interactions

Impaired Antibody Response Is Associated with Histone-Release, Organ Dysfunction and Mortality in Critically Ill COVID-19 Patients.

Lagedal, Rickard; Eriksson, Oskar; Sörman, Anna; Huckriede, Joram B et al.

Part of Journal of clinical medicine, 2022.

DOI for Impaired Antibody Response Is Associated with Histone-Release, Organ Dysfunction and Mortality in Critically Ill COVID-19 Patients. Download full text (pdf) of Impaired Antibody Response Is Associated with Histone-Release, Organ Dysfunction and Mortality in Critically Ill COVID-19 Patients.

Modulation of Neutrophil Activity by Soluble Complement Cleavage Products-An In-Depth Analysis

Wohlgemuth, Lisa; Stratmann, Alexander Elias Paul; Muennich, Frederik; Bernhard, Stefan et al.

Part of Cells, 2022.

DOI for Modulation of Neutrophil Activity by Soluble Complement Cleavage Products-An In-Depth Analysis Download full text (pdf) of Modulation of Neutrophil Activity by Soluble Complement Cleavage Products-An In-Depth Analysis

Variation of Complement Protein Levels in Maternal Plasma and Umbilical Cord Blood during Normal Pregnancy: An Observational Study

Saleh, Muna; Compagno, Michele; Pihl, Sofia; Strevens, Helena et al.

Part of Journal of Clinical Medicine, 2022.

DOI for Variation of Complement Protein Levels in Maternal Plasma and Umbilical Cord Blood during Normal Pregnancy: An Observational Study Download full text (pdf) of Variation of Complement Protein Levels in Maternal Plasma and Umbilical Cord Blood during Normal Pregnancy: An Observational Study

Cell Surface Functionalization with Heparin-Conjugated Lipid to Suppress Blood Activation

Asawa, Kenta; Ishihara, Kazuhiko; Nilsson Ekdahl, Kristina; Nilsson, Bo et al.

Part of Advanced Functional Materials, 2021.

DOI for Cell Surface Functionalization with Heparin-Conjugated Lipid to Suppress Blood Activation

Complement as driver of systemic inflammation and organ failure in trauma, burn, and sepsis

Mannes, Marco; Schmidt, Christoph Q.; Nilsson, Bo; Nilsson Ekdahl, Kristina et al.

Part of Seminars in Immunopathology, p. 773-788, 2021.

DOI for Complement as driver of systemic inflammation and organ failure in trauma, burn, and sepsis Download full text (pdf) of Complement as driver of systemic inflammation and organ failure in trauma, burn, and sepsis

Harnessing hyaluronic acid-based nanoparticles for combination therapy: A novel approach for suppressing systemic inflammation and to promote antitumor macrophage polarization

Rangasami, Vignesh K.; Samanta, Sumanta; Parihar, Vijay Singh; Asawa, Kenta et al.

Part of Carbohydrate Polymers, 2021.

DOI for Harnessing hyaluronic acid-based nanoparticles for combination therapy: A novel approach for suppressing systemic inflammation and to promote antitumor macrophage polarization

Hemocompatibility of Nanotitania-Nanocellulose Hybrid Materials

Svensson, Fredric G.; Manivel, Vivek Anand; Seisenbaeva, Gulaim A.; Kessler, Vadim G. et al.

Part of Nanomaterials, 2021.

DOI for Hemocompatibility of Nanotitania-Nanocellulose Hybrid Materials Download full text (pdf) of Hemocompatibility of Nanotitania-Nanocellulose Hybrid Materials

Immunopathophysiology of trauma-related acute kidney injury

Messerer, David A. C.; Halbgebauer, Rebecca; Nilsson, Bo; Pavenstaedt, Hermann et al.

Part of Nature Reviews Nephrology, p. 91-111, 2021.

DOI for Immunopathophysiology of trauma-related acute kidney injury

Induction of Spontaneous Liposome Adsorption by Exogenous Surface Modification with Cell-Penetrating Peptide-Conjugated Lipids

Sato, Yuya; Asawa, Kenta; Huang, Tianwei; Noiri, Makoto et al.

Part of Langmuir, p. 9711-9723, 2021.

DOI for Induction of Spontaneous Liposome Adsorption by Exogenous Surface Modification with Cell-Penetrating Peptide-Conjugated Lipids

Interdialytic weight gain of less than 2.5% seems to limit cardiac damage during hemodialysis

Goto, Junko; Forsberg, Ulf; Jonsson, Per; Matsuda, Kenichi et al.

Part of International Journal of Artificial Organs, p. 539-550, 2021.

DOI for Interdialytic weight gain of less than 2.5% seems to limit cardiac damage during hemodialysis Download full text (pdf) of Interdialytic weight gain of less than 2.5% seems to limit cardiac damage during hemodialysis

Interleukin 8 Elicits Rapid Physiological Changes in Neutrophils That Are Altered by Inflammatory Conditions

Bernhard, Stefan; Hug, Stefan; Stratmann, Alexander Elias Paul; Erber, Maike et al.

Part of Journal of Innate Immunity, p. 225-241, 2021.

DOI for Interleukin 8 Elicits Rapid Physiological Changes in Neutrophils That Are Altered by Inflammatory Conditions Download full text (pdf) of Interleukin 8 Elicits Rapid Physiological Changes in Neutrophils That Are Altered by Inflammatory Conditions

Pluronic Micelle-Mediated Tissue Factor Silencing Enhances Hemocompatibility, Stemness, Differentiation Potential, and Paracrine Signaling of Mesenchymal Stem Cells

Rangasami, Vignesh K.; Nawale, Ganesh N.; Asawa, Kenta; Kadekar, Sandeep et al.

Part of Biomacromolecules, p. 1980-1989, 2021.

DOI for Pluronic Micelle-Mediated Tissue Factor Silencing Enhances Hemocompatibility, Stemness, Differentiation Potential, and Paracrine Signaling of Mesenchymal Stem Cells Download full text (pdf) of Pluronic Micelle-Mediated Tissue Factor Silencing Enhances Hemocompatibility, Stemness, Differentiation Potential, and Paracrine Signaling of Mesenchymal Stem Cells

Synthesis of poly(2-methacryloyloxyethyl phosphorylcholine)-conjugated lipids and their characterization and surface properties of modified liposomes for protein interactions

Adler, Anna; Inoue, Yuuki; Sato, Yuya; Ishihara, Kazuhiko et al.

Part of Biomaterials Science, p. 5854-5867, 2021.

DOI for Synthesis of poly(2-methacryloyloxyethyl phosphorylcholine)-conjugated lipids and their characterization and surface properties of modified liposomes for protein interactions

The Complex Relationship between C4b-Binding Protein, Warfarin, and Antiphospholipid Antibodies

Grosso, Giorgia; Sandholm, Kerstin; Antovic, Aleksandra; Gunnarsson, Iva et al.

Part of Thrombosis and Haemostasis, p. 1299-1309, 2021.

DOI for The Complex Relationship between C4b-Binding Protein, Warfarin, and Antiphospholipid Antibodies

The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System

Lipcsey, Miklós; Persson, Barbro; Eriksson, Oskar; Blom, Anna M. et al.

Part of Frontiers in Immunology, 2021.

DOI for The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System Download full text (pdf) of The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System

Transcriptome analysis of post-mortem brain tissue reveals up-regulation of the complement cascade in a subgroup of schizophrenia patients

Lindholm Carlström, Eva; Niazi, Adnan; Etemadikhah, Mitra; Halvardson, Jonatan et al.

Part of Genes, 2021.

DOI for Transcriptome analysis of post-mortem brain tissue reveals up-regulation of the complement cascade in a subgroup of schizophrenia patients Download full text (pdf) of Transcriptome analysis of post-mortem brain tissue reveals up-regulation of the complement cascade in a subgroup of schizophrenia patients

Animal-Free Human Whole Blood Sepsis Model to Study Changes in Innate Immunity

Messerer, David Alexander Christian; Vidoni, Laura; Erber, Maike; Stratmann, Alexander Elias Paul et al.

Part of Frontiers in Immunology, 2020.

DOI for Animal-Free Human Whole Blood Sepsis Model to Study Changes in Innate Immunity Download full text (pdf) of Animal-Free Human Whole Blood Sepsis Model to Study Changes in Innate Immunity

Assessment of the Role of C3(H2O) in the Alternative Pathway

Fromell, Karin; Adler, Anna; Åman, Amanda; Manivel, Vivek Anand et al.

Part of Frontiers in Immunology, 2020.

DOI for Assessment of the Role of C3(H2O) in the Alternative Pathway Download full text (pdf) of Assessment of the Role of C3(H2O) in the Alternative Pathway

Blood type A associates with critical COVID-19 and death in a Swedish cohort

Hultström, Michael; Persson, Barbro; Eriksson, Oskar; Lipcsey, Miklós et al.

Part of Critical Care, 2020.

DOI for Blood type A associates with critical COVID-19 and death in a Swedish cohort Download full text (pdf) of Blood type A associates with critical COVID-19 and death in a Swedish cohort

Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy

Mastellos, Dimitrios C.; Pires da Silva, Bruno G. P.; Fonseca, Benedito A. L.; Fonseca, Natasha P. et al.

Part of Clinical Immunology, 2020.

DOI for Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy

Complement deposition, C4d, on platelets is associated with vascular events in systemic lupus erythematosus

Svenungsson, Elisabet; Gustafsson, Johanna T.; Grosso, Giorgia; Rossides, Marios et al.

Part of Rheumatology, p. 3264-3274, 2020.

DOI for Complement deposition, C4d, on platelets is associated with vascular events in systemic lupus erythematosus Download full text (pdf) of Complement deposition, C4d, on platelets is associated with vascular events in systemic lupus erythematosus

Discrepancies in plasma levels of complement components measured by a newly introduced commercially available magnetic bead technique compared to presently available clinical reference intervals

Sandholm, Kerstin; Carlsson, Hanna; Persson, Barbro; Skattum, Lillemor et al.

Part of Scandinavian Journal of Immunology, 2020.

DOI for Discrepancies in plasma levels of complement components measured by a newly introduced commercially available magnetic bead technique compared to presently available clinical reference intervals

Identification of Metal-Binding Peptides and Their Conjugation onto Nanoparticles of Superparamagnetic Iron Oxides and Liposomes

Kodama, Tomonobu; Yoshihara, Akifumi; Goel, Isha; Sekino, Masaki et al.

Part of ACS Applied Materials and Interfaces, p. 24623-24634, 2020.

DOI for Identification of Metal-Binding Peptides and Their Conjugation onto Nanoparticles of Superparamagnetic Iron Oxides and Liposomes

Mannose-Binding Lectin is Associated with Thrombosis and Coagulopathy in Critically Ill COVID-19 Patients

Eriksson, Oskar; Hultström, Michael; Persson, Barbro; Lipcsey, Miklós et al.

Part of Thrombosis and haemostasis, p. 1720-1724, 2020.

DOI for Mannose-Binding Lectin is Associated with Thrombosis and Coagulopathy in Critically Ill COVID-19 Patients

Poly(2-aminoethyl methacrylate)-based polyampholyte brush surface with carboxylic groups to improve blood compatibility

Azuma, Tomoyuki; Matsushita, Taishi; Manivel, Vivek Anand; Nilsson Ekdahl, Kristina et al.

Part of Journal of Biomaterials Science. Polymer Edition, p. 679-693, 2020.

DOI for Poly(2-aminoethyl methacrylate)-based polyampholyte brush surface with carboxylic groups to improve blood compatibility

Potential of Cell Surface Engineering with Biocompatible Polymers for Biomedical Applications

Teramura, Yuji; Nilsson Ekdahl, Kristina; Fromell, Karin; Nilsson, Bo et al.

Part of Langmuir, p. 12088-12106, 2020.

DOI for Potential of Cell Surface Engineering with Biocompatible Polymers for Biomedical Applications

Promotion of cell membrane fusion by cell-cell attachment through cell surface modification with functional peptide-PEG-lipids

Yoshihara, Akifumi; Watanabe, Sayumi; Goel, Isha; Ishihara, Kazuhiko et al.

Part of Biomaterials, 2020.

DOI for Promotion of cell membrane fusion by cell-cell attachment through cell surface modification with functional peptide-PEG-lipids

Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock

Halbgebauer, Rebecca; Karasu, Ebru; Braun, Christian K.; Palmer, Annette et al.

Part of Frontiers in Immunology, 2020.

DOI for Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock Download full text (pdf) of Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock

A case of systemic lupus erythematosus with C1q deficiency, increased serum interferon-a levels and high serum interferogenic activity

Bolin, Karin; Eloranta, Maija-Leena; Kozyrev, Sergey V.; Dahlqvist, Johanna et al.

Part of Rheumatology, p. 918-919, 2019.

DOI for A case of systemic lupus erythematosus with C1q deficiency, increased serum interferon-a levels and high serum interferogenic activity

A human whole-blood model to study the activation of innate immunity system triggered by nanoparticles as a demonstrator for toxicity

N.Ekdahl, Kristina; Fromell, Karin; Mohlin, Camilla; Teramura, Yuji et al.

Part of Science and Technology of Advanced Materials, p. 688-698, 2019.

DOI for A human whole-blood model to study the activation of innate immunity system triggered by nanoparticles as a demonstrator for toxicity Download full text (pdf) of A human whole-blood model to study the activation of innate immunity system triggered by nanoparticles as a demonstrator for toxicity

C3-Glomerulopathy Autoantibodies Mediate Distinct Effects on Complement C3-and C5-Convertases

Zhao, Fei; Afonso, Sara; Lindner, Susanne; Hartmann, Andrea et al.

Part of Frontiers in Immunology, 2019.

DOI for C3-Glomerulopathy Autoantibodies Mediate Distinct Effects on Complement C3-and C5-Convertases Download full text (pdf) of C3-Glomerulopathy Autoantibodies Mediate Distinct Effects on Complement C3-and C5-Convertases

Current and Future Approaches for Monitoring Responses to Anti-complement Therapeutics

Mohebnasab, Maedeh; Eriksson, Oskar; Persson, Barbro; Sandholm, Kerstin et al.

Part of Frontiers in Immunology, 2019.

DOI for Current and Future Approaches for Monitoring Responses to Anti-complement Therapeutics Download full text (pdf) of Current and Future Approaches for Monitoring Responses to Anti-complement Therapeutics

Evaluation of a Novel Immunoassay for Quantification of C1q for Clinical Diagnostic Use

Sandholm, Kerstin; Persson, Barbro; Skattum, Lillemor; Eggertsen, Gosta et al.

Part of Frontiers in Immunology, 2019.

DOI for Evaluation of a Novel Immunoassay for Quantification of C1q for Clinical Diagnostic Use Download full text (pdf) of Evaluation of a Novel Immunoassay for Quantification of C1q for Clinical Diagnostic Use

Exposure of von Willebrand Factor on Isolated Hepatocytes Promotes Tethering of Platelets to the Cell Surface

Gustafson, Elisabet K.; Hamad, Osama A.; Deckmyn, Hans; Barbu, Andreea R et al.

Part of Transplantation, p. 1630-1638, 2019.

DOI for Exposure of von Willebrand Factor on Isolated Hepatocytes Promotes Tethering of Platelets to the Cell Surface

Is generation of C3(H₂O) necessary for activation of the alternative pathway in real life?

Nilsson Ekdahl, Kristina; Mohlin, Camilla; Adler, Anna; Åman, Amanda et al.

Part of Molecular Immunology, p. 353-361, 2019.

DOI for Is generation of C3(H₂O) necessary for activation of the alternative pathway in real life? Download full text (pdf) of Is generation of C3(H₂O) necessary for activation of the alternative pathway in real life?

Modification of human MSC surface with oligopeptide-PEG-lipids for selective binding to activated endothelium

Noiri, Makoto; Asawa, Kenta; Okada, Naoya; Kodama, Tomonobu et al.

Part of Journal of Biomedical Materials Research. Part A, p. 1779-1792, 2019.

DOI for Modification of human MSC surface with oligopeptide-PEG-lipids for selective binding to activated endothelium

Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation

von Zur-Mühlen, Bengt; Lundgren, Torbjorn; Bayman, Levent; Berne, Christian et al.

Part of Transplantation, p. 630-637, 2019.

DOI for Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation Download full text (pdf) of Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation

Optimization of Islet Microencapsulation with Thin Polymer Membranes for Long-Term Stability

Toda, Shota; Fattah, Artin; Asawa, Kenta; Nakamura, Naoko et al.

Part of Micromachines, 2019.

DOI for Optimization of Islet Microencapsulation with Thin Polymer Membranes for Long-Term Stability Download full text (pdf) of Optimization of Islet Microencapsulation with Thin Polymer Membranes for Long-Term Stability

Polyvinylalcohol-carbazate (PVAC) reduces red blood cell hemolysis

Sellberg, Felix; Fredriksson, Fanny; Engstrand, Thomas; Bowden, Tim et al.

Part of PLOS ONE, 2019.

DOI for Polyvinylalcohol-carbazate (PVAC) reduces red blood cell hemolysis Download full text (pdf) of Polyvinylalcohol-carbazate (PVAC) reduces red blood cell hemolysis

PROTECTIVE EFFECTS OF THE COMPLEMENT INHIBITOR COMPSTATIN CP40 IN HEMORRHAGIC SHOCK

van Griensven, Martijn; Ricklin, Daniel; Denk, Stephanie; Halbgebauer, Rebecca et al.

Part of Shock, p. 78-87, 2019.

DOI for PROTECTIVE EFFECTS OF THE COMPLEMENT INHIBITOR COMPSTATIN CP40 IN HEMORRHAGIC SHOCK

'Stealth' corporate innovation: an emerging threat for therapeutic drug development

Mastellos, Dimitrios C.; Blom, Anna M.; Connolly, E. Sander; Daha, Mohamed R. et al.

Part of Nature Immunology, p. 1409-1413, 2019.

DOI for 'Stealth' corporate innovation: an emerging threat for therapeutic drug development

Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction

Karasu, Ebru; Nilsson, Bo; Köhl, Jörg; Lambris, John D. et al.

Part of Frontiers in Immunology, 2019.

DOI for Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction Download full text (pdf) of Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction

The Human Platelet as an Innate Immune Cell: Interactions Between Activated Platelets and the Complement System

Eriksson, Oskar; Mohlin, Camilla; Nilsson, Bo; N. Ekdahl, Kristina

Part of Frontiers in Immunology, 2019.

DOI for The Human Platelet as an Innate Immune Cell: Interactions Between Activated Platelets and the Complement System Download full text (pdf) of The Human Platelet as an Innate Immune Cell: Interactions Between Activated Platelets and the Complement System

Two subgroups in systemic lupus erythematosus with features of antiphospholipid or Sjogren's syndrome differ in molecular signatures and treatment perspectives

Idborg, Helena; Zandian, Arash; Sandberg, Ann-Sofi; Nilsson, Bo et al.

Part of Arthritis Research & Therapy, 2019.

DOI for Two subgroups in systemic lupus erythematosus with features of antiphospholipid or Sjogren's syndrome differ in molecular signatures and treatment perspectives Download full text (pdf) of Two subgroups in systemic lupus erythematosus with features of antiphospholipid or Sjogren's syndrome differ in molecular signatures and treatment perspectives

Validation of an MPC polymer coating to attenuate surface- induced cross-talk between the complement and coagulation systems in whole blood in in vitro and in vivo models

Asif, Sana; Asawa, Kenta; Yuuki, Inoue; Ishihara, Kazuhiko et al.

Part of Macromolecular Bioscience, 2019.

DOI for Validation of an MPC polymer coating to attenuate surface- induced cross-talk between the complement and coagulation systems in whole blood in in vitro and in vivo models

Author Correction: Dispersion of TiO₂ nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins

Seisenbaeva, Gulaim A.; Fromell, Karin; Vinogradov, Vasiliy V.; Terekhov, Aleksey N. et al.

Part of Scientific Reports, 2018.

DOI for Author Correction: Dispersion of TiO₂ nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins Download full text (pdf) of Author Correction: Dispersion of TiO₂ nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins

Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions

Huber-Lang, Markus; Nilsson Ekdahl, Kristina; Wiegner, Rebecca; Fromell, Karin et al.

Part of Seminars in Immunopathology, p. 87-102, 2018.

DOI for Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions Download full text (pdf) of Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions

Contact (kallikrein/kinin) system activation in whole human blood induced by low concentrations of α-Fe2O3 nanoparticles.

Nilsson Ekdahl, Kristina; Davoodpour, Padideh; Ekstrand-Hammarström, Barbro; Fromell, Karin et al.

Part of Nanomedicine, p. 735-744, 2018.

DOI for Contact (kallikrein/kinin) system activation in whole human blood induced by low concentrations of α-Fe2O3 nanoparticles.

Generation of an alternative pathway convertase by contact-activated C3 is dependent on the conformation of C3

Fromell, Karin; Johansson, Ulrika; Dührkop, Claudia; Adler, Anna et al.

Part of Molecular Immunology, p. 193-193, 2018.

DOI for Generation of an alternative pathway convertase by contact-activated C3 is dependent on the conformation of C3

Interpretation of Serological Complement Biomarkers in Disease

Nilsson Ekdahl, Kristina; Persson, Barbro; Mohlin, Camilla; Sandholm, Kerstin et al.

Part of Frontiers in Immunology, 2018.

DOI for Interpretation of Serological Complement Biomarkers in Disease Download full text (pdf) of Interpretation of Serological Complement Biomarkers in Disease

Is the polarized secretion of complement factor H of importance in age-related macular degeneration?

Mohlin, Camilla; Petrus-Reurer, Sandra; Lanner, Fredrik; Sandholm, Kerstin et al.

Part of Investigative Ophthalmology and Visual Science, 2018.

PROTECTIVE EFFECTS OF THE COMPLEMENT INHIBITOR COMPSTATIN CP40 IN HEMORRHAGIC SHOCK

van Griensven, Martijn; Ricklin, Daniel; Denk, Stephanie; Halbgebauer, Rebecca et al.

Part of Shock, p. 117-118, 2018.

DOI for PROTECTIVE EFFECTS OF THE COMPLEMENT INHIBITOR COMPSTATIN CP40 IN HEMORRHAGIC SHOCK

Safety profile after prolonged C3 inhibition

Reis, Edimara S.; Berger, Nadja; Wang, Xin; Koutsogiannaki, Sophia et al.

Part of Clinical Immunology, p. 96-106, 2018.

DOI for Safety profile after prolonged C3 inhibition

Shiga toxin 2a binds antithrombin and heparin, but does not directly activate platelets

Knabl, Ludwig; Berktold, Michael; Hamad, Osama A.; Fromell, Karin et al.

Part of International Journal of Medical Microbiology, p. 969-976, 2018.

DOI for Shiga toxin 2a binds antithrombin and heparin, but does not directly activate platelets

The lectin pathway of complement and the contact/kallikrein system are integrated

Fromell, Karin; Dührkop, Claudia; Kozarcanin, Huda; Johansson, Ulrika et al.

Part of Molecular Immunology, p. 151-152, 2018.

DOI for The lectin pathway of complement and the contact/kallikrein system are integrated

The multifaceted role of complement in kidney transplantation

Biglarnia, Ali-Reza; Huber-Lang, Markus; Mohlin, Camilla; Nilsson Ekdahl, Kristina et al.

Part of Nature Reviews Nephrology, p. 767-781, 2018.

DOI for The multifaceted role of complement in kidney transplantation

The Optimization of the Hepatocyte Surface Modification Procedures in Terms of Heparin and Apyrase for Improving Hepatocyte Engraftment

Ogasawara, Hiroyuki; Teramura, Yuji; Imura, Takehiro; Inagaki, Akiko et al.

Part of Transplantation, p. S727-S727, 2018.

DOI for The Optimization of the Hepatocyte Surface Modification Procedures in Terms of Heparin and Apyrase for Improving Hepatocyte Engraftment

A protective role of complement regulators linked to a PEG phospholipid construct in reducing ischemic reperfusion injury in transplantation

Nilsson, Bo; Asif, Sana; Ekdahl N., Kristina; Manell, Elin et al.

Part of Molecular Immunology, p. 208-208, 2017.

DOI for A protective role of complement regulators linked to a PEG phospholipid construct in reducing ischemic reperfusion injury in transplantation

Absence of conformational change in complement factor 3 and factor XII adsorbed to acrylate polymers is related to a high degree of polymer backbone flexibility

Fromell, Karin; Yang, Yi; Nilsson Ekdahl, Kristina; Nilsson, Bo et al.

Part of Biointerphases, 2017.

DOI for Absence of conformational change in complement factor 3 and factor XII adsorbed to acrylate polymers is related to a high degree of polymer backbone flexibility Download full text (pdf) of Absence of conformational change in complement factor 3 and factor XII adsorbed to acrylate polymers is related to a high degree of polymer backbone flexibility

Cardiovascular disease in haemodialysis: role of the intravascular innate immune system.

Ekdahl, Kristina N; Soveri, Inga; Hilborn, Jöns; Fellström, Bengt et al.

Part of Nature Reviews Nephrology, p. 285-296, 2017.

DOI for Cardiovascular disease in haemodialysis: role of the intravascular innate immune system.

Cell Adhesion Induced Using Surface Modification with Cell-Penetrating Peptide-Conjugated Poly(ethylene glycol)-Lipid: A New Cell Glue for 3D Cell-Based Structures

Teramura, Yuji; Asif, Sana; Nilsson Ekdahl, Kristina; Gustafson, Elisabet K. et al.

Part of ACS Applied Materials and Interfaces, p. 244-254, 2017.

DOI for Cell Adhesion Induced Using Surface Modification with Cell-Penetrating Peptide-Conjugated Poly(ethylene glycol)-Lipid: A New Cell Glue for 3D Cell-Based Structures

Complement C5a Functions as a Master Switch for the pH Balance in Neutrophils Exerting Fundamental Immunometabolic Effects

Denk, Stephanie; Neher, Miriam D.; Messerer, David A. C.; Wiegner, Rebecca et al.

Part of Journal of Immunology, p. 4846-4854, 2017.

DOI for Complement C5a Functions as a Master Switch for the pH Balance in Neutrophils Exerting Fundamental Immunometabolic Effects

Complement system proteins in human embryonic stem cell-derived retinal pigment epithelial cells co-cultured with or without porcine retina

Mohlin, C.; Petrus-Reurer, S.; Lanner, F.; Sandholm, K. et al.

Part of Molecular Immunology, p. 162-163, 2017.

DOI for Complement system proteins in human embryonic stem cell-derived retinal pigment epithelial cells co-cultured with or without porcine retina

Control of IBMIR induced by fresh and cryopreserved hepatocytes by low molecular weight dextran sulfate

Gustafson, Elisabet; Asif, Sana; Kozarcanin, Huda; Meurling, Staffan et al.

Part of Cell Transplantation, p. 71-81, 2017.

DOI for Control of IBMIR induced by fresh and cryopreserved hepatocytes by low molecular weight dextran sulfate Download full text (pdf) of Control of IBMIR induced by fresh and cryopreserved hepatocytes by low molecular weight dextran sulfate

Dispersion of TiO₂ nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins

Seisenbaeva, Gulaim A.; Fromell, Karin; Vinogradov, Vasiliy V.; Terekhov, Aleksey N. et al.

Part of Scientific Reports, 2017.

DOI for Dispersion of TiO₂ nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins Download full text (pdf) of Dispersion of TiO₂ nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins

Forms of contact-activated C3 associated with AP convertase formation

Fromell, Karin; Dührkop, Claudia; Johansson, Ulrika; Nilsson Ekdahl, Kristina et al.

Part of Molecular Immunology, p. 141-141, 2017.

DOI for Forms of contact-activated C3 associated with AP convertase formation

Method development and validation for the quantitation of the complement inhibitor Cp40 in human and cynomolgus monkey plasma by UPLC-ESI-MS

Primikyri, Alexandra; Papanastasiou, Malvina; Sarigiannis, Yiannis; Koutsogiannaki, Sophia et al.

Part of Journal of chromatography. B, p. 19-26, 2017.

DOI for Method development and validation for the quantitation of the complement inhibitor Cp40 in human and cynomolgus monkey plasma by UPLC-ESI-MS

The innate immunity response: A key factor in biocompatibility

Ekdahl, Kristina N; Fromell, Karin; Hilborn, Jöns; Nilsson, Bo

Part of Bioresorbable Polymers for Biomedical Applications, p. 85-94, 2017.

The link between morphology and complement in ocular disease

Mohlin, Camilla; Sandholm, Kerstin; Nilsson Ekdahl, Kristina; Nilsson, Bo

Part of Molecular Immunology, p. 84-99, 2017.

DOI for The link between morphology and complement in ocular disease

Activation of Complement C3 Does NotHamper the Outcome of Experimental Intramuscular Islet Transplantation

Espes, Daniel; Pekna, Marcela; Nilsson, Bo; Carlsson, Per-Ola

Part of Transplantation, p. E6-E7, 2016.

DOI for Activation of Complement C3 Does NotHamper the Outcome of Experimental Intramuscular Islet Transplantation

Characterization of innate immunity in an extended whole blood model of human islet allotransplantation

Hårdstedt, Maria; Lindblom, Susanne; Karlsson-Para, Alex; Nilsson, Bo et al.

Part of Cell Transplantation, p. 503-515, 2016.

DOI for Characterization of innate immunity in an extended whole blood model of human islet allotransplantation

Chondroitin sulfate coated gold nanoparticles: a new strategy to resolve multidrug resistance and thromboinflammation

Gurav, Deepanjali; Varghese, Oommen P.; Hamad, Osama A.; Nilsson, Bo et al.

Part of Chemical Communications, p. 966-969, 2016.

DOI for Chondroitin sulfate coated gold nanoparticles: a new strategy to resolve multidrug resistance and thromboinflammation

Complement analysis 2016: Clinical indications, laboratory diagnostics and quality control

Prohaszka, Zoltan; Nilsson, Bo; Frazer-Abel, Ashley; Kirschfink, Michael

Part of Immunobiology, p. 1247-1258, 2016.

DOI for Complement analysis 2016: Clinical indications, laboratory diagnostics and quality control

Complement inhibition in biomaterial- and biosurface-induced thromboinflammation

Ekdahl, Kristina N.; Huang, Shan; Nilsson, Bo; Teramura, Yuji

Part of Seminars in Immunology, p. 268-277, 2016.

DOI for Complement inhibition in biomaterial- and biosurface-induced thromboinflammation

Complement Receptor 2 is increased in cerebrospinal fluid of multiple sclerosis patients and regulates C3 function

Lindblom, Rickard; Aeinehband, Shahin; Ström, Mikael; Al Nimer, Faiez et al.

Part of Clinical Immunology, p. 89-95, 2016.

DOI for Complement Receptor 2 is increased in cerebrospinal fluid of multiple sclerosis patients and regulates C3 function Download full text (pdf) of Complement Receptor 2 is increased in cerebrospinal fluid of multiple sclerosis patients and regulates C3 function

Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation

Nilsson Ekdahl, Kristina; Teramura, Yuji; Hamad, Osama A.; Asif, Sana et al.

Part of Immunological Reviews, p. 245-269, 2016.

DOI for Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation

Development and characterization of an innovtive heparin coating to stabilize and protect liposomes against adverse immune reactions

Duehrkop, Claudia; Leneweit, Gero; Heyder, Christoph; Fromell, Karin et al.

Part of Colloids and Surfaces B, p. 576-583, 2016.

DOI for Development and characterization of an innovtive heparin coating to stabilize and protect liposomes against adverse immune reactions

Evidence of contact activation in patients suffering from ST-elevation myocardial infarction

Christensen, Kjeld; Kozarcanin, Huda; Ekdahl, Kristina N.; Nilsson, Bo

Part of Thrombosis Research, p. 158-162, 2016.

DOI for Evidence of contact activation in patients suffering from ST-elevation myocardial infarction

Heparinization of cell surfaces with short pepetide-conjugated PEG-lipid regulates thromboinflammation in thransplantation of human MSCs and hepatocytes

Asif, Sana; Ekdahl, Kristina N; Fromell, Karin; Gustafson, Elisabet et al.

Part of Acta Biomaterialia, p. 194-205, 2016.

DOI for Heparinization of cell surfaces with short pepetide-conjugated PEG-lipid regulates thromboinflammation in thransplantation of human MSCs and hepatocytes

Multifunctional Hyaluronic Acid and Chondroitin Sulfate Nanoparticles: Impact of Glycosaminoglycan Presentation on Receptor Mediated Cellular Uptake and Immune Activation

Oommen, Oommen Podiyan; Duehrkop, Claudia; Nilsson, Bo; Hilborn, Jöns et al.

Part of ACS Applied Materials and Interfaces, p. 20614-20624, 2016.

DOI for Multifunctional Hyaluronic Acid and Chondroitin Sulfate Nanoparticles: Impact of Glycosaminoglycan Presentation on Receptor Mediated Cellular Uptake and Immune Activation

Reciprocal relationship between contact and complement system activation on artificial polymers exposed to whole human blood

Huang, Shan; Engberg, Anna E.; Jonsson, Nina; Sandholm, Kerstin et al.

Part of Biomaterials, p. 111-119, 2016.

DOI for Reciprocal relationship between contact and complement system activation on artificial polymers exposed to whole human blood

The lectin complement pathway inhibitor MAP-1 is an upstream regulator of the coagulation cascade

Skjoedt, Mikkel-Ole; Pavlov, Vasile; Kozarcanin, Huda; Willer, Anton et al.

Part of Immunobiology, p. 1209-1209, 2016.

DOI for The lectin complement pathway inhibitor MAP-1 is an upstream regulator of the coagulation cascade

The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation

Kozarcanin, Huda; Lood, Christian; Munthe-Fog, Lea; Sandholm, Kerstin et al.

Part of Journal of Thrombosis and Haemostasis, p. 531-545, 2016.

DOI for The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation

Type 1 Diabetes Mellitus Donor Mesenchymal. Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro

Davies, Lindsay C.; Alm, Jessica J.; Heldring, Nina; Moll, Guido et al.

Part of Stem Cells Translational Medicine, p. 1485-1495, 2016.

DOI for Type 1 Diabetes Mellitus Donor Mesenchymal. Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro

A novel model for studies of blood-mediated long-term responses to cellular transplants

Hårdstedt, Maria; Lindblom, Susanne; Hong, Jaan; Nilsson, Bo et al.

Part of Upsala Journal of Medical Sciences, p. 28-39, 2015.

DOI for A novel model for studies of blood-mediated long-term responses to cellular transplants

Cell Surface Engineering for Regulation of Immune Reactions in Cell Therapy

Teramura, Yuji; Asif, Sana; Nilsson Ekdahl, Kristina; Nilsson, Bo

Part of Advances in Experimental Medicine and Biology, p. 189-209, 2015.

DOI for Cell Surface Engineering for Regulation of Immune Reactions in Cell Therapy

Complement and platelets: Mutual interference in the immune network

Speth, Cornelia; Rambach, Guenter; Wuerzner, Reinhard; Lass-Floerl, Cornelia et al.

Part of Molecular Immunology, p. 108-118, 2015.

DOI for Complement and platelets: Mutual interference in the immune network

Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

Aeinehband, Shahin; Lindblom, Rickard P F; Al Nimer, Faiez; Vijayaraghavan, Swetha et al.

Part of PLOS ONE, 2015.

DOI for Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis Download full text (pdf) of Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response

Lindblom, Rickard P. F.; Berg, Alexander; Strom, Mikael; Aeinehband, Shahin et al.

Part of Journal of Neuroinflammation, 2015.

DOI for Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response Download full text (pdf) of Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response

Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention

Mastellos, Dimitrios C.; Yancopoulou, Despina; Kokkinos, Petros; Huber-Lang, Markus et al.

Part of European Journal of Clinical Investigation, p. 423-440, 2015.

DOI for Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention