Publications Lena Claesson-Welsh

Publications in DiVA 

Publications in PubMed

Selected publications: 

  1. Sjöberg E, Melssen M, Richards M, Ding Y, Chanoca C, Chen D, Nwadozi E, Pal S, Love DT, Ninchoji T, Shibuya M, Simons M, Dimberg A, Claesson-Welsh L. Endothelial VEGFR2-PLCγ signaling regulates vascular permeability and antitumor immunity through eNOS/Src. Clin Invest. 2023, 133(20):e161366.
  2. Jin Y, Ding Y, Richards M, Kaakinen M, Giese W, Baumann E, Szymborska A, Rosa A, Nordling S, Schimmel L, Akmeric EB, Pena A, Nwadozi E, Jamalpour M, Holstein K, Sáinz-Jaspeado M, Bernabeu M, Welsh M, Gordon E, Franco CA, Vestweber D, Eklund L, Gerhardt H, Claesson-Welsh L. Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis. Nat Cardiovasc Res. 2022, 1:1156–1173. See also News and Views “YES to junctions, no to Src” by Simons M and Toomre D, Nat Cardiovasc Res. 2022, 1:1116–1118.
  3. Richards M, Nwadozi E, Pal S, Kaakinen M, Gloger M, Sjoberg E, Betsholz C, Eklund L, Nordling S, Claesson-Welsh L Claudin 5 heterogeneously modifies endothelial cell barrier integrity in the peripheral vascular system. Elife. 2022, 11:e78517.
  4. Sáinz-Jaspead M, Smitm RO, Plunde O, Pawelzik S-C, Jin Y, Nordling S, Ding Y, Aspenström P, Hedlund M, Bastianello G, Ascione F, Li Q, Saygili Demir C, Fernando D, Daniel G, Franco-Cereceda A, Kroon J, Foiani M, Petrova T, Kilimann MW, Bäck M, Claesson-Welsh L. Palmdelphin regulates nuclear resilience to mechanical stress in the endothelium. Circulation. 2021, 144(20):1629-1645.
  5. Richards M, Pal S, Sjöberg E, Martinsson P, Venkatraman L, Claesson-Welsh L. Intra-vessel heterogeneity establishes enhanced sites of macromolecular leakage downstream of laminin α5. Cell Rep. 2021, 35(12):109268.
  6. Claesson-Welsh L, Dejana E, McDonald DM. Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies. Trends Mol Med. 2021, 27(4):314331.
  7. Smith RO, Ninchoji T, Gordon E, André H, Dejana E, Vestweber D, Kvanta A, Claesson-Welsh L. Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin. Elife. 2020, 9. pii: e54056.
  8. Honkura N, Richards M, Lavina B, Sainz Jaspeado M, Betsholtz C, Claesson-Welsh L. Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events. Nat Commun, 2018, 9:2746.
  9. Morin E, Sjöberg E, Tjomsland V, Testini C, Kieflemariam S, Sjöblom T, Claesson-Welsh L. Reduced angiogenesis and tumor proliferation in human pancreatic cancer with VEGF receptor-2/neuropilin1 complex in trans. J Pathol. 2018, 246(3):311-322. See also Commentary Sarabipour S, Mac Gabhann F, “Tumor and endothelial cells collaborate via transcellular receptor complexs.” J. Pathol. Volume 247, Issue 2.
  10. Li X, Padhan N, Sjöström EO, Roche FP, Testini C, Honkura N, Sáinz-Jaspeado M, Gordon E, Bentley K, Philippides A, Tolmachev V, Dejana E, Stan RV, Vestweber D, Ballmer-Hofer K, Betsholtz C, Pietras K, Jansson L, Claesson-Welsh L. VEGFR2 pY949 signalig regulates adherens junction integrity and metastatic spread. Nat Commun. 2016, 7:11017.

Last modified: 2023-11-06