Publications in DiVA – Pontus Aspenström

Altered cytoskeletal status in the transition from proneural to mesenchymal glioblastoma subtypes

Keller, Maureen; Blom, Magdalena; Liu Conze, Lei; Guo, Min et al.

Part of Scientific Reports, 2022.

DOI for Altered cytoskeletal status in the transition from proneural to mesenchymal glioblastoma subtypes Download full text (pdf) of Altered cytoskeletal status in the transition from proneural to mesenchymal glioblastoma subtypes

Diabetes downregulates the antimicrobial peptide psoriasin and increases E. coli burden in the urinary bladder

Mohanty, Soumitra; Kamolvit, Witchuda; Scheffschick, Andrea; Björklund, Anneli et al.

Part of Nature Communications, 2022.

DOI for Diabetes downregulates the antimicrobial peptide psoriasin and increases E. coli burden in the urinary bladder Download full text (pdf) of Diabetes downregulates the antimicrobial peptide psoriasin and increases E. coli burden in the urinary bladder

The Role of Fast-Cycling Atypical RHO GTPases in Cancer

Aspenström, Pontus

Part of Cancers, 2022.

DOI for The Role of Fast-Cycling Atypical RHO GTPases in Cancer Download full text (pdf) of The Role of Fast-Cycling Atypical RHO GTPases in Cancer

Cytoskeletal Organization Correlates to Motility and Invasiveness of Malignant Mesothelioma Cells

Keller, Maureen; Reis, Katarina; Hjerpe, Anders; Dobra, Katalin et al.

Part of Cancers, 2021.

DOI for Cytoskeletal Organization Correlates to Motility and Invasiveness of Malignant Mesothelioma Cells Download full text (pdf) of Cytoskeletal Organization Correlates to Motility and Invasiveness of Malignant Mesothelioma Cells

Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium

Sainz-Jaspeado, Miguel; Smith, Ross O.; Plunde, Oscar; Pawelzik, Sven-Christian et al.

Part of Circulation, p. 1629-1645, 2021.

DOI for Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium Download full text (pdf) of Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium

Syndecan-1 Overexpressing Mesothelioma Cells Inhibit Proliferation, Wound Healing, and Tube Formation of Endothelial Cells

Javadi, Joman; Heidari-Hamedani, Ghazal; Schmalzl, Angelika; Szatmari, Tunde et al.

Part of Cancers, 2021.

DOI for Syndecan-1 Overexpressing Mesothelioma Cells Inhibit Proliferation, Wound Healing, and Tube Formation of Endothelial Cells Download full text (pdf) of Syndecan-1 Overexpressing Mesothelioma Cells Inhibit Proliferation, Wound Healing, and Tube Formation of Endothelial Cells

Inhibitors of cytoskeletal dynamics in malignant mesothelioma.

Reis, Katarina; Arbiser, Jack L; Hjerpe, Anders; Dobra, Katalin et al.

Part of OncoTarget, p. 4637-4647, 2020.

DOI for Inhibitors of cytoskeletal dynamics in malignant mesothelioma. Download full text (pdf) of Inhibitors of cytoskeletal dynamics in malignant mesothelioma.

The Intrinsic GDP/GTP Exchange Activities of Cdc42 and Rac1 Are A Critical Determinants for Their Specific Effects on Mobilization of the Actin Filament System

Aspenström, Pontus

Part of Cells, 2019.

DOI for The Intrinsic GDP/GTP Exchange Activities of Cdc42 and Rac1 Are A Critical Determinants for Their Specific Effects on Mobilization of the Actin Filament System Download full text (pdf) of The Intrinsic GDP/GTP Exchange Activities of Cdc42 and Rac1 Are A Critical Determinants for Their Specific Effects on Mobilization of the Actin Filament System

Activated Rho GTPases in Cancer-The Beginning of a New Paradigm

Aspenström, Pontus

Part of International Journal of Molecular Sciences, 2018.

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Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses.

MacAskill, Andrew F.; Rinholm, Johanne E.; Twelvetrees, Alison E.; Arancibia-Carcamo, I. Lorena et al.

Part of Neuron, p. 541-555, 2009.

DOI for Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses.

Roles of F-BAR/PCH Proteins in the Regulation of Membrane Dynamics and Actin Reorganization

Aspenström, Pontus

Part of International Review of Cell and Molecular Biology, p. 1-31, 2009.

DOI for Roles of F-BAR/PCH Proteins in the Regulation of Membrane Dynamics and Actin Reorganization

WAFL, a new protein involved in regulation of early endocytictransport at the intersection of actin and microtubule dynamics

Viklund, Ing-Marie; Aspenström, Pontus; Meas-Yedid, Vannary; Zhang, Bo et al.

Part of Experimental Cell Research, p. 1040-1052, 2009.

DOI for WAFL, a new protein involved in regulation of early endocytictransport at the intersection of actin and microtubule dynamics

Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase

Saotome, Masao; Safiulina, Dzhamilja; Szabadkai, György; Das, Sudipto et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 20728-20733, 2008.

DOI for Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase

Characterization of RhoBTB-dependent Cul3 ubiquitin ligase complexes--evidence for an autoregulatory mechanism

Berthold, Jessica; Schenková, Kristína; Ramos, Sonia; Miura, Yoshie et al.

Part of Experimental Cell Research, p. 3453-3465, 2008.

DOI for Characterization of RhoBTB-dependent Cul3 ubiquitin ligase complexes--evidence for an autoregulatory mechanism

The atypical Rho GTPase Wrch1 collaborates with the nonreceptor tyrosine kinases Pyk2 and Src in regulating cytoskeletal dynamics

Ruusala, Aino; Aspenström, Pontus

Part of Molecular and Cellular Biology, p. 1802-14, 2008.

DOI for The atypical Rho GTPase Wrch1 collaborates with the nonreceptor tyrosine kinases Pyk2 and Src in regulating cytoskeletal dynamics

Angiomotin regulates endothelial cell migration during embryonic angiogenesis

Aase, Karin; Ernkvist, Mira; Ebarasi, Lwaki; Jakobsson, Lars et al.

Part of Genes & Development, p. 2055-2068, 2007.

DOI for Angiomotin regulates endothelial cell migration during embryonic angiogenesis

Oleic acid and docosahexaenoic acid cause an increase in the paracellular absorption of hydrophilic compounds in an experimental model of human absorptive enterocytes

Aspenström-Fagerlund, Bitte; Ring, Linda; Aspenström, Pontus; Tallkvist, Jonas et al.

Part of Toxicology, p. 12-23, 2007.

DOI for Oleic acid and docosahexaenoic acid cause an increase in the paracellular absorption of hydrophilic compounds in an experimental model of human absorptive enterocytes

Taking Rho GTPases to the next level: the cellular functions of atypical Rho GTPases

Aspenström, Pontus; Ruusala, Aino; Pacholsky, Dirk

Part of Experimental Cell Research, p. 3673-3679, 2007.

DOI for Taking Rho GTPases to the next level: the cellular functions of atypical Rho GTPases

Pombe Cdc15 homology proteins: regulators of membrane dynamics and the actin cytoskeleton

Aspenström, Pontus; Fransson, Åsa; Richnau, Ninna

Part of TIBS -Trends in Biochemical Sciences. Regular ed., p. 670-679, 2006.

DOI for Pombe Cdc15 homology proteins: regulators of membrane dynamics and the actin cytoskeleton

The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics

Aspenström, Pontus; Richnau, Ninna; Johansson, Ann-Sofi

Part of Experimental Cell Research, p. 2180-2194, 2006.

DOI for The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics

The verprolins as regulators of actin dynamics.

Aspenström, Pontus

Part of Actin-monomer-binding proteins., p. 97-106, 2006.

DOI for The verprolins as regulators of actin dynamics.

Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis

Edlund, Sofia; Lee, So Young; Grimsby, Susanne; Zhang, Shouthing et al.

Part of Molecular and Cellular Biology, p. 1475-1488, 2005.

DOI for Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis

The verprolin family of proteins: Regulators of cell morphogenesis and endocytosis

Aspenström, Pontus

Part of FEBS Letters, p. 5253-5259, 2005.

DOI for The verprolin family of proteins: Regulators of cell morphogenesis and endocytosis

A gain of function mutation in the activation loop of platelet-derived growth factor beta-receptor deregulates its kinase activity

Chiara, Federica; Goumans, Marie-José; Forsberg, Henrik; Åhgrén, Aive et al.

Part of Journal of Biological Chemistry, p. 42516-42527, 2004.

DOI for A gain of function mutation in the activation loop of platelet-derived growth factor beta-receptor deregulates its kinase activity

Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways

Jaffe, Aron B; Aspenström, Pontus; Hall, Alan

Part of Molecular and Cellular Biology, p. 1736-1746, 2004.

DOI for Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways

Integration of signalling pathways regulated by small GTPases and calcium

Aspenström, Pontus

Part of Biochimica et Biophysica Acta, p. 51-58, 2004.

DOI for Integration of signalling pathways regulated by small GTPases and calcium

Isolation and characterisation of DOCK8, a member of the DOCK180-related regulators of cell morphology

Ruusala, Aino; Aspenström, Pontus

Part of FEBS Letters, p. 159-166, 2004.

DOI for Isolation and characterisation of DOCK8, a member of the DOCK180-related regulators of cell morphology

Rho GTPases have diverse effects on the organization of the actin filament system

Aspenström, Pontus; Fransson, Åsa; Saras, Jan

Part of Biochemical Journal, p. 327-337, 2004.

RICH-1 has a BIN/Amphiphysin/Rvsp domain responsible for binding to membrane lipids and tubulation of liposomes

Richnau, Ninna; Fransson, Åsa; Farsad, Khashayar; Aspenström, Pontus

Part of Biochemical and Biophysical Research Communications - BBRC, p. 1034-1042, 2004.

DOI for RICH-1 has a BIN/Amphiphysin/Rvsp domain responsible for binding to membrane lipids and tubulation of liposomes

Smad7 is required for TGF-ß-induced activation of the small GTPase Cdc42

Edlund, Sofia; Landström, Maréne; Heldin, Carl-Henrik; Aspenström, Pontus

Part of Journal of Cell Science, p. 1835-1847, 2004.

DOI for Smad7 is required for TGF-ß-induced activation of the small GTPase Cdc42

The mammalian verprolin homologue WIRE participates in receptor-mediated endocytosis and regulation of the actin filament system by distinct mechanisms

Aspenström, Pontus

Part of Experimental Cell Research, p. 485-498, 2004.

DOI for The mammalian verprolin homologue WIRE participates in receptor-mediated endocytosis and regulation of the actin filament system by distinct mechanisms

Vilse, a conserved Rac/Cdc42 GAP mediating Robo repulsion in tracheal cells and axons

Lundström, Annika; Gallio, Marco; Englund, Camilla; Steneberg, Pär et al.

Part of Genes & Development, p. 2161-2171, 2004.

DOI for Vilse, a conserved Rac/Cdc42 GAP mediating Robo repulsion in tracheal cells and axons

Wrch1 is a GTPase-deficient Cdc42-like protein with unusual binding characteristics and cellular effects.

Saras, Jan; Wollberg, Patrick; Aspenström, Pontus

Part of Exp Cell Res, p. 356-69, 2004.

Down-regulation of Rac activity during beta 2 integrin-mediated adhesion of human neutrophils

Dib, Karim; Melander, Fredrik; Axelsson, Lena; Dagher, Marie-Claire et al.

Part of Journal of Biological Chemistry, p. 24181-24188, 2003.

DOI for Down-regulation of Rac activity during beta 2 integrin-mediated adhesion of human neutrophils

Effect of transforming growth factor-beta on calcium homeostasis inprostate carcinoma cells.

Gizatullina, Zemfira Z.; Grapengiesser, Eva; Shabalina, Irina G.; Nedergaard, Jan et al.

Part of Biochem Biophys Res Commun, p. 643-, 2003.

Transforming growth factor-beta1-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3

Edlund, Sofia; Bu, Shizhong; Schuster, Norbert; Aspenström, Pontus et al.

Part of Molecular Biology of the Cell, p. 529-544, 2003.

DOI for Transforming growth factor-beta1-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3

The WASP-binding protein WIRE has a role in the regulation of the actin filament system downstream of the platelet-derived growth factor receptor

Aspenström, Pontus

Part of Experimental Cell Research, p. 21-33, 2002.

DOI for The WASP-binding protein WIRE has a role in the regulation of the actin filament system downstream of the platelet-derived growth factor receptor

Transforming growth factor-beta-induced mobilization of actin cytoskeleton required signaling by small GTPases Cdc42 and RhoA

Edlund, Sofia; Landström, Maréne; Heldin, Carl-Henrik; Aspenström, Pontus

Part of Molecular Biology of the Cell, p. 902-914, 2002.

DOI for Transforming growth factor-beta-induced mobilization of actin cytoskeleton required signaling by small GTPases Cdc42 and RhoA

Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes.

Westerberg, Lisa; Greicius, Gediminas; Snapper, Scott B.; Aspenström, Pontus et al.

Part of Blood, p. 1086-1094, 2001.

DOI for Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes.