Genes associated with hearing loss visualised in new study
2021-12-06
Researchers at IGP and the Department of Surgical Sciences have shown in a new study that differences in the risk of age-related hearing loss is partly due to genetic factors that affect structures and functions in the human inner ear. The study was recently published in BMC Medicine.
Age-related hearing loss is the most common form of hearing loss. In the new study, IGP researchers Mathias Rask-Andersen and Åsa Johansson, together with Wei Liu and Helge Rask-Andersen at the Department of Surgical Sciences, have performed functional follow-up studies of candidate genes identified in from genome-wide association studies by analysis in the human inner ear. Using high-resolution microscopy, they could detect and visualize proteins associated with hearing loss. The study shows that age-related hearing loss is to some extent caused by genetic factors.
More information:
Uppsala University web news
Mathias Rask-Andersen's and Åsa Johansson’s research
Article in BMC Medicine
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