About the STorM program
Cancer arises as a consequence of a series of genetic alterations in any of the more than 200 specialized cell types of our body. Through these genetic changes, cancer cells may evade the strict control of cell division and form a tumor. Recent studies highlight the importance of communication between cancer cells and their surrounding tissue (the tumor microenvironment) to enable a tumor to develop into a clinically manifested disease. Various cell types in the tumor microenvironment provide a range of factors that promote the initiation of cancer, fuel the growth of malignant cells, facilitate the spread of the disease and make tumors resistant to treatment.
The Swedish Tumor Microenvironment (STorM) network leverages the power of thirty internationally leading research groups in the field spanning across the entire country. The overarching aim of the program is to identify novel communication pathways within the tumor microenvironment that can be exploited as cancer drug targets and biomarkers. The program will foster cross-disciplinary studies which optimally combines experimental studies in cell and animal models, correlative analyses of clinical samples, and cutting-edge technology.
Presently the STorM program consolidates many research groups and supports a strong integration with methodology-based SciLifeLab units. It is expected that there will be a significant synergistic effect through this format where the biomedical- and technology-based research groups will support each other.