Research and education at IGP
News
Newsletter
Recent research papers from IGP
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Al-Amin, Rasel A.; Gallant, Caroline J.; Muthelo, Phathutshedzo M.; Landegren, Ulf
Sensitive Measurement of Drug-Target Engagement by a Cellular Thermal Shift Assay with Multiplex Proximity Extension Readout
2021
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Mulder, Jan; Lindqvist, Isa; Rasmusson, Annica; Husen, Evelina; Rönnelid, Johan; Kumlien, Eva; Rostami, Elham; Virhammar, Johan; Cunningham, Janet L.
Indirect immunofluorescence for detecting anti-neuronal autoimmunity in CSF after COVID-19-Possibilities and pitfalls
2021
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Secilmis, Deniz; Hillerton, Thomas; Nelander, Sven; Sonnhammer, Erik L. L.
Inferring the experimental design for accurate gene regulatory network inference
2021
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Zhao, Linxuan; Xing, Pengwei; Polavarapu, Vamsi Krishna; Zhao, Miao; Valero-Martínez, Blanca; Dang, Yonglong; Maturi, Naga Prathyusha; Mathot, Lucy; Neves, Inês; Yildirim, Irem; Swartling, Fredrik J.; Sjöblom, Tobias; Uhrbom, Lene; Chen, Xingqi
FACT-seq: profiling histone modifications in formalin-fixed paraffin-embedded samples with low cell numbers
2021
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Tillmar, Andreas; Sturk-Andreaggi, Kimberly; Daniels-Higginbotham, Jennifer; Tyler Thomas, Jacqueline; Marshall, Charla
The FORCE Panel: An All-in-One SNP Marker Set for Confirming Investigative Genetic Genealogy Leads and for General Forensic Applications
2021
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Karlsson Sundbaum, Johanna; Baecklund, Eva; Eriksson, Niclas; Kohnke, Hugo; Wallenberg, Matilda; Cavalli, Marco; Wadelius, Claes; Wadelius, Mia; Hallberg, Pär
Genome-wide association study of liver enzyme elevation in rheumatoid arthritis patients starting methotrexate.
2021
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Bauer, Wolfgang; Weber, Marcus; Diehl-Wiesenecker, Eva; Galtung, Noa; Prpic, Monika; Somasundaram, Rajan; Tauber, Rudolf; Schwenk, Jochen M.; Micke, Patrick; Kappert, Kai
Plasma Proteome Fingerprints Reveal Distinctiveness and Clinical Outcome of SARS-CoV-2 Infection
2021
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Tsakonas, Georgios; Martin-Bernabe, Alfonso; Rounis, Konstantinos; Moreno-Ruiz, Pablo; Botling, Johan; De Petris, Luigi; Ylipää, Antti; Mezheyeuski, Artur; Micke, Patrick; Östman, Arne; Ekman, Simon
High Density of NRF2 Expression in Malignant Cells Is Associated with Increased Risk of CNS Metastasis in Early-Stage NSCLC
2021
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Yamaguchi, Yoko; Saito, Akira; Horie, Masafumi; Aoki, Akira; Micke, Patrick; Ohshima, Mitsuhiro; Kappert, Kai
Targeting hepatocyte growth factor in epithelial-stromal interactions in an in vitro experimental model of human periodontitis.
2021
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Backman, Max; La Fleur, Linnea; Kurppa, Pinja; Djureinovic, Dijana; Elfving, Hedvig; Brunnström, Hans; Mattsson, Johanna S M; Lindberg, Amanda; Pontén, Victor; Eltahir, Mohamed; Mangsbo, Sara; Gulyas, Miklos; Isaksson, Johan; Jirström, Karin; Kärre, Klas; Leandersson, Karin; Mezheyeuski, Artur; Ponten, Fredrik; Strell, Carina; Lindskog, Cecilia; Botling, Johan; Micke, Patrick
Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer
2021
Welcome to IGP
The department conducts advanced research and education in areas such as clinical immunology, medical genetics and genomics, pathology, oncology, neuro-oncology, vascular biology, molecular tools and medical radiation sciences.
Some of our activities are integrated with clinics at Uppsala University Hospital.
Find examples of research at the Department in Our research in images.
Follow us on Twitter: @IgpUu
New research findings from IGP
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New technology to study DNA in archived tissue samples
2022-01-19
Researchers at IGP have developed a technology that allows studies of DNA profiles in archived tissue samples. The technology permits investigators to better understand regulation of gene activity in cancer and precision medicine.
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New genes associated with relapse of acute myeloid leukemia
2022-01-13
In the blood cancer type acute myeloid leukemia, it is common that patients relapse some time after treatment. Researchers from IGP have in a new study identified genes that seem to be associated with the risk of relapse. The findings may form the basis for new treatment strategies and contribute to better survival for patients with acute myeloid leukemia.
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Fish embryos and AI can replace some mouse experiments in cancer research
2021-12-20
Researchers at IGP have used AI to develop a new method to study brain cancer. The method is based on transplanting tumour cells from patients to fish embryos, followed by observation with AI. The method, which is described in the scientific journal Neuro-Oncology, can partly replace current mouse models for studying tumour growth and treatment.