Welcome to IGP
The department conducts advanced research and education in areas such as clinical immunology, medical genetics and genomics, pathology, oncology, neuro-oncology, vascular biology, molecular tools and medical radiation sciences.
- Media highlights for our most recent paper!https://t.co/5LAKOBIJYb#PrecisionMedicine #neuroblastoma #Cancer #systemsbiology #pharmacology #drugdiscovery
- Uppsalaforskare har med hjälp av en datoralgoritm identifierat en ny lovande behandling mot sjukdomen neuroblastom, en nervcancer hos barn som kan vara livshotande. Upptäckten kan på längre sikt leda till en ny form av behandling. https://t.co/WJ7pSnFQDS
- Ulf Gyllensten får Rudbeckmedaljen för sina framgångsrika studier av genetik och molekylär epidemiologi hos människa. https://t.co/VvzworRsM6
New research findings from IGP
Smart algorithm finds possible future treatment for childhood cancer
Using a computer algorithm, scientists at IGP have identified a promising new treatment for neuroblastoma. This form of cancer in children, which occurs in specialised nerve cells in the sympathetic nervous system, may be life-threatening. In the long term the discovery, described in the latest issue of the scientific journal Nature Communications, may result in a new form of treatment for children in whom the disease is severe or at an advanced stage.
Drug against epilepsy inhibits tumour development in the brain
Medication against a certain type of epilepsy can be a new way to treat malignant brain tumours in infants. A specific mTOR inhibitor can cross the blood-brain barrier and both reach and attack the tumour where it is located. This is shown by IGP researchers, in collaboration with American and British colleagues, and the results are published in the scientific journal Cell Stem Cell.
New combination of drugs effective against aggressive brain tumour
Researchers at IGP have identified a certain group of patients with malignant glioblastoma brain tumours that respond to a therapy targeting the cancer gene MYCN. The research findings are published in the scientific journal Cell Death & Disease.
Correlation found between loss of chromosome Y and genetic instability
In an international collaboration, researchers from IGP have shown that loss of chromosome Y in the blood in men can function as an indicator of genetic instability, which in turn can affect the susceptibility for cancer in other parts of the body. The study has been published in the journal Nature.
Analysis using whole genome sequencing gives more accuracy
A new study from IGP shows that whole genome sequencing contributes to increasing the accuracy in genetic studies, which in turn can improve the understanding of how biomarkers can be used to discover diseases. The results are published in the scientific journal Scientific Reports.