Research and education at IGP
News
Newsletter
Recent research papers from IGP
-
Mazzarella, Luca; Enblad, Gunilla; Olweus, Johanna; Malmberg, Karl-Johan; Jerkeman, Mats
Advances in immune therapies in hematological malignancies
2022
-
Hasselblatt, Martin; Thomas, Christian; Federico, Aniello; Bens, Susanne; Hellström, Mats; Casar Borota, Olivera; Kordes, Uwe; Neumann, Julia E.; Dottermusch, Matthias; Rodriguez, Fausto J.; Lo, Andrea C.; Cheng, Sylvia; Hendson, Glenda; Hukin, Juliette; Hartmann, Christian; Koch, Arend; Capper, David; Siebert, Reiner; Paulus, Werner; Nemes, Karolina; Johann, Pascal D.; Fruehwald, Michael C.; Kool, Marcel
Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC
2022
-
Weinreich, Ilse; Bengtsson, Mats; Lauronen, Jouni; Naper, Christian; Lokk, Kaie; Helanterä, Ilkka; Andrésdóttir, Margrét Birna; Sørensen, Søren Schwartz; Wennberg, Lars; Reisaeter, Anna Varberg; Møller, Bjarne; Koefoed-Nielsen, Pernille
Scandiatransplant acceptable mismatch program-10 years with an effective strategy for transplanting highly sensitized patients.
2022
-
Al-Sabri, Mohamed H.; Nikpour, Maryam; Clemensson, Laura Emily; Attwood, Misty M.; Williams, Michael J.; Rask-Andersen, Mathias; Mwinyi, Jessica; Schiöth, Helgi B.
The regulatory role of AP-2 beta in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential
2022
-
Golec, Ewelina; Ekstrom, Alexander; Noga, Maciej; Omar-Hmeadi, Muhmmad; Lund, Per-Eric; Villoutreix, Bruno O.; Krus, Ulrika; Wozniak, Katarzyna; Korsgren, Olle; Renstrom, Erik; Barg, Sebastian; King, Ben C.; Blom, Anna M.
Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets
2022
-
Fransson, Samuel; Tilly, David; Strand, Robin
Patient specific deep learning based segmentation for magnetic resonance guided prostate radiotherapy
2022
-
Olsen, Thale Kristin; Dyberg, Cecilia; Embaie, Bethel Tesfai; Alchahin, Adele; Milosevic, Jelena; Ding, Jane; Otte, Jörg; Tümmler, Conny; Myrberg, Ida Hed; Westerhout, Ellen M.; Koster, Jan; Versteeg, Rogier; Ding, Han-Fei; Kogner, Per; Johnsen, John Inge; Sykes, David B.; Baryawno, Ninib
DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma
2022
-
Osterman, Erik; Helenius, Louise; Larsson, Christina; Jakobsson, Sofia; Majumder, Tamali; Blomberg, Anders; Wickenberg, Jennie; Linder, Fredrik
Surgery for acute cholecystitis in severely comorbid patients: a population-based study on acute cholecystitis
2022
-
Raykova, Doroteya; Kermpatsou, Despoina; Malmqvist, Tony; Harrison, Philip J; Rubin Sander, Marie; Stiller, Christiane; Heldin, Johan; Leino, Mattias; Ricardo, Sara; Klemm, Anna H; David, Leonor; Spjuth, Ola; Vemuri, Kalyani; Dimberg, Anna; Sundqvist, Anders; Norlin, Maria; Klaesson, Axel; Kampf, Caroline; Söderberg, Ola
A method for Boolean analysis of protein interactions at a molecular level
2022
-
Hillerton, Thomas; Secilmi, Deniz; Nelander, Sven; Sonnhammer, Erik L. L.; Valencia, Alfonso
Fast and accurate gene regulatory network inference by normalized least squares regression
2022
Welcome to IGP
The department conducts advanced research and education in areas such as clinical immunology, medical genetics and genomics, pathology, oncology, neuro-oncology, vascular biology, molecular tools and medical radiation sciences.
Some of our activities are integrated with clinics at Uppsala University Hospital.
Find examples of research at the Department in Our research in images.
Follow us on Twitter: @IgpUu
New research findings from IGP
-
Genetic background associated with physically active lifestyle
2022-09-08
In a large international study, researchers at IGP have identified DNA regions that are associated with physical activity or leisure screen time. The findings confirm that physical activity is beneficial for health and suggest that a more sedentary lifestyle can be due to how the muscles respond to exercise.
-
Blood clot formation in cerebral cavernous malformations
2022-08-23
Blood coagulation and blood clot formation are relevant for the disease cerebral cavernoma, CCM. Therefore, antithrombotic therapy may be beneficial for cavernoma patients. This is shown in a new study from IGP.
-
Y chromosome loss causes heart failure and death from cardiovascular disease
2022-07-14
Loss of the Y chromosome in blood cells of men is associated with disease and mortality, but no clear causal relationship has previously been identified. Now, researchers from IGP show in an international study in the journal Science that loss of the Y chromosome in white blood cells causes development of fibrosis in the heart, impaired heart function and death from cardiovascular diseases in men.