An international research team, where Marcel den Hoed has participated, has identified hundreds of genetic variants that are linked with age at first sex and birth of the first child. The study shows that a combination of genetics, social predictors and the environment drives early or late reproductive onset and that it can be related to later life diseases.

Researchers at IGP have discovered lymph node-like structures close to the tumour in brain cancer patients, where immune cells can be activated to attack the tumour. They also found that immunotherapy enhanced the formation of these structures in a mouse model. This discovery suggests new opportunities to regulate the anti-tumour response of the immune system.

Tumour cells can affect immune cells in the body so that the tumour is not attacked by the immune defence. In a new research paper from IGP, the researchers show that some types of immune cells are more common in more aggressive tumours of the cancer form mantle cell lymphoma. The findings suggest a possibility to develop drugs that can improve the prognosis for mantle cell lymphoma patients.