Magnus Essand – Cancerimmunterapi

CD4⁺ T cell-induced inflammatory cell death controls immune-evasive tumours

Kruse, Bastian; Buzzai, Anthony C.; Shridhar, Naveen; Braun, Andreas D. et al.

Ingår i Nature, s. 1033-1040, 2023

• DOI för CD4⁺ T cell-induced inflammatory cell death controls immune-evasive tumours
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Complementarity-determining region clustering may cause CAR-T cell dysfunction

Sarén, Tina; Saronio, Giulia; Marti Torrell, Paula; Zhu, Xu et al.

Ingår i Nature Communications, 2023

• DOI för Complementarity-determining region clustering may cause CAR-T cell dysfunction
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Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer

Vaccaro, Alessandra; van de Walle, Tiarne; Ramachandran, Mohanraj; Essand, Magnus et al.

Ingår i Frontiers in Immunology, 2023

• DOI för Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer
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Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients

Sarén, Tina; Ramachandran, Mohanraj; Gammelgård, Gustav; Lövgren, Tanja et al.

Ingår i Clinical Cancer Research, s. 4139-4152, 2023

• DOI för Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients
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Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Ramachandran, Mohanraj; Vaccaro, Alessandra; van de Walle, Tiarne; Georganaki, Maria et al.

Ingår i Cancer Cell, s. 1134-1151, 2023

• DOI för Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
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CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers

Jin, Chuan; Ma, Jing; Ramachandran, Mohanraj; Yu, Di et al.

Ingår i Nature Biomedical Engineering, s. 830-841, 2022

• DOI för CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers
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CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation

Konstantinidis, Evangelos; Molisak, Agnieszka; Perrin, Florian; Streubel-Gallasch, Linn et al.

Ingår i Molecular Therapy Nucleic Acids, s. 450-461, 2022

• DOI för CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation
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Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response

Jin, Chuan; Ali, Arwa; Iskantar, Alexandros; Fotaki, Grammatiki et al.

Ingår i Oncoimmunology, 2022

• DOI för Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response
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Ixovex-1, a novel oncolytic E1B-mutated adenovirus

Anwar, Mohiemen; Arendt, Maja-Louise; Ramachandran, Mohanraj; Carlsson, Anette et al.

Ingår i Cancer Gene Therapy, s. 1628-1635, 2022

• DOI för Ixovex-1, a novel oncolytic E1B-mutated adenovirus
• Ladda ner fulltext (pdf) av Ixovex-1, a novel oncolytic E1B-mutated adenovirus

Targeting circulating monocytes with CCL2-loaded liposomes armed with an oncolytic adenovirus

Iscaro, Alessandra; Jones, Christian; Forbes, Neil; Mughal, Amina et al.

Ingår i Nanomedicine, 2022

• DOI för Targeting circulating monocytes with CCL2-loaded liposomes armed with an oncolytic adenovirus

Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy

Sjöholm, Therese; Korenyushkin, Alexander; Gammelgård, Gustav; Sarén, Tina et al.

Ingår i Cancer Imaging, 2022

• DOI för Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy
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ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression

Darweesh, Mahmoud; Younis, Shady; Hajikhezri, Zamaneh; Ali, Arwa et al.

Ingår i Frontiers in Immunology, 2022

• DOI för ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
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Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma

van Hooren, Luuk; Vaccaro, Alessandra; Ramachandran, Mohanraj; Vazaios, Konstantinos et al.

Ingår i Nature Communications, 2021

• DOI för Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma
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Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy

Deng, Siyuan; Iscaro, Alessandra; Zambito, Giorgia; Mijiti, Yimin et al.

Ingår i Nanomaterials, 2021

• DOI för Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy
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IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma

Martikainen, Miika; Ramachandran, Mohanraj; Lugano, Roberta; Ma, Jing et al.

Ingår i MOLECULAR THERAPY-ONCOLYTICS, s. 37-46, 2021

• DOI för IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma
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Perivascular macrophages regulate blood flow following tissue damage

Vågesjö, Evelina; Parv, Kristel; Ahl, David; Seignez, Cedric et al.

Ingår i Circulation Research, s. 1694-1707, 2021

• DOI för Perivascular macrophages regulate blood flow following tissue damage

Tertiary Lymphoid Structures in the Central Nervous System: Implications for Glioblastoma

van de Walle, Tiarne; Vaccaro, Alessandra; Ramachandran, Mohanraj; Pietilä, Ilkka et al.

Ingår i Frontiers in Immunology, 2021

• DOI för Tertiary Lymphoid Structures in the Central Nervous System: Implications for Glioblastoma
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Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain

Rostami, Jinar; Fotaki, Grammatiki; Sirois, Julien; Mzezewa, Ropafadzo et al.

Ingår i Journal of Neuroinflammation, 2020

• DOI för Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain
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Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer

Ma, Jing; Ramachandran, Mohanraj; Jin, Chuan; Quijano-Rubio, Clara et al.

Ingår i Cell Death and Disease, 2020

• DOI för Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer
• Ladda ner fulltext (pdf) av Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer

TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment

Depreter, Barbara; Weening, Karin E.; Vandepoele, Karl; Essand, Magnus et al.

Ingår i Haematologica, s. 1306-1316, 2020

• DOI för TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment
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Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

Georganaki, Maria; Ramachandran, Mohanraj; Tuit, Sander; Nunez, Nicolas Gonzalo et al.

Ingår i Oncoimmunology, 2020

• DOI för Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy
• Ladda ner fulltext (pdf) av Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

Čančer, Matko; Hutter, Sonja; Holmberg Olausson, Karl; Rosén, Gabriela et al.

Ingår i Cell Stem Cell, s. 855-870, 2019

• DOI för Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
• Ladda ner fulltext (pdf) av Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Xie, Yuan; Sundström, Anders; Maturi, Naga P; Tan, E-Jean et al.

Ingår i Journal of Pathology, s. 228-240, 2019

• DOI för LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Virus-Based Immunotherapy of Glioblastoma

Martikainen, Miika; Essand, Magnus

Ingår i Cancers, 2019

• DOI för Virus-Based Immunotherapy of Glioblastoma
• Ladda ner fulltext (pdf) av Virus-Based Immunotherapy of Glioblastoma

A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia

Enblad, Gunilla; Karlsson, Hannah; Gammelgård, Gustav; Wenthe, Jessica et al.

Ingår i Clinical Cancer Research, s. 6185-6194, 2018

• DOI för A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia

Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models

Fotaki, Grammatiki; Jin, Chuan; Kerzeli, Iliana Kyriaki; Ramachandran, Mohanraj et al.

Ingår i Oncoimmunology, 2018

• DOI för Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models
• Ladda ner fulltext (pdf) av Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models

CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis

Lugano, Roberta; Vemuri, Kalyani; Yu, Di; Bergqvist, Michael et al.

Ingår i Journal of Clinical Investigation, s. 3280-3297, 2018

• DOI för CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis
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Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

Roche, Francis P.; Pietilä, Ilkka; Kaito, Hiroshi; Sjöström, Elisabet O. et al.

Ingår i Molecular Cancer Therapeutics, s. 1961-1972, 2018

• DOI för Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity
• Ladda ner fulltext (pdf) av Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

Modifying melanoma immune microenvironment by heterologous prime-boost vaccination with adenovirus and Modified Vaccinia Ankara virus vectors

Shridhar, N.; Ruotsalainen, J.; van der Sluis, T.; Rogava, M. et al.

Ingår i Experimental dermatology, 2018

Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth

Younis, Shady; Kamel, Wael; Falkeborn, Tina; Wang, Hao et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2018

• DOI för Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth

Perivascular macrophages regulate blood flow following tissue damage

Vågesjö, Evelina; Seignez, Cedric; Christoffersson, Gustaf; Herrera Hidalgo, Carmen et al.

Ingår i European Journal of Clinical Investigation, s. 44-45, 2018

• DOI för Perivascular macrophages regulate blood flow following tissue damage

Pro-inflammatory allogeneic DCs promote activation of bystander immune cells and thereby license antigen-specific T-cell responses

Fotaki, Grammatiki; Jin, Chuan; Ramachandran, Mohanraj; Kerzeli, Iliana Kyriaki et al.

Ingår i Oncoimmunology, 2018

• DOI för Pro-inflammatory allogeneic DCs promote activation of bystander immune cells and thereby license antigen-specific T-cell responses

Adenovirus, Semliki Forest virus and vaccinia virus-induced immunogenic cell death augments oncolytic virus immunotherapy

Ma, Jing; Ramachandran, Mohanraj; Jin, Chuan; Essand, Magnus et al.

Ingår i Scandinavian Journal of Immunology, s. 341-341, 2017

CAR T-Cells with Induced Secretion of Helicobacter Pylori Neutrophil-Activating Protein (HP-NAP) Yields Improved Anti-Tumor Activity and Reduced Immunosuppression

Essand, Magnus; Ma, Jing; Jin, Chuan; Ramachandran, Mohanraj et al.

Ingår i Molecular Therapy, s. 288-288, 2017

Immunological biomarkers correlate to survival in CAR19-treated patients

Lövgren, Tanja; Wenthe, Jessica; Karlsson, S. C. Hannah; Gammelgård, Gustav et al.

Ingår i Scandinavian Journal of Immunology, s. 337-337, 2017

Multiple viruses rely on the stress-induced protein ZC3H11A for efficient replication

Younis, Shady; Kamel, Wael; Wang, Hao; Yu, Di et al.

2017

Oncolytic alphavirus SFV-VA7 efficiently eradicates subcutaneous and orthotopic human prostate tumours in mice

Martikainen, Miika; Ruotsalainen, Janne; Tuomela, Johanna; Harkonen, Pirkko et al.

Ingår i British Journal of Cancer, s. 51-55, 2017

• DOI för Oncolytic alphavirus SFV-VA7 efficiently eradicates subcutaneous and orthotopic human prostate tumours in mice

PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c

Pan, Gang; Ameur, Adam; Enroth, Stefan; Bysani, Madhusudhan et al.

Ingår i Nucleic Acids Research, s. 2408-2422, 2017

• DOI för PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c

Preclinical Evaluation of AdVince, an Oncolytic Adenovirus Adapted for Treatment of Liver Metastases from Neuroendocrine Cancer

Yu, Di; Leja, Justyna; Loskog, Angelica S.; Hellman, Per et al.

Ingår i Neuroendocrinology, s. 54-66, 2017

• DOI för Preclinical Evaluation of AdVince, an Oncolytic Adenovirus Adapted for Treatment of Liver Metastases from Neuroendocrine Cancer

Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus

Ramachandran, Mohanraj; Yu, Di; Dyczynski, Matheus; Baskaran, Sathishkumar et al.

Ingår i Clinical Cancer Research, s. 1519-1530, 2017

• DOI för Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus

The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells

Ramachandran, Mohanraj; Dimberg, Anna; Essand, Magnus

Ingår i Seminars in Cancer Biology, s. 23-35, 2017

• DOI för The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells
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A Clinical Trial Using Third Generation CD19 Targeting CAR T Cells for Relapsed Lymphoma and Leukemia

Enblad, Gunilla; Karlsson, Hannah; Wenthe, Jessica; Wikström, Kristina I. et al.

Ingår i Molecular Therapy, 2016

Allogeneic dendritic cells (AlloDCs) transduced with an infection enhanced adenovirus as adjuvant for cancer immunotherapy

Fotaki, Grammatiki; Jin, Chuan; Karlsson-Parra, Alex; Yu, Di et al.

Ingår i CANCER IMMUNOLOGY RESEARCH, 2016

• DOI för Allogeneic dendritic cells (AlloDCs) transduced with an infection enhanced adenovirus as adjuvant for cancer immunotherapy

Avidity characterization of genetically engineered T-cells with novel and established approaches

Hillerdal, Victoria; Boura, Vanessa F.; Björkelund, Hanna; Andersson, Karl et al.

Ingår i BMC Immunology, 2016

• DOI för Avidity characterization of genetically engineered T-cells with novel and established approaches
• Ladda ner fulltext (pdf) av Avidity characterization of genetically engineered T-cells with novel and established approaches

CD19-targeting third generation CAR T cells for relapsed and refractory lymphoma and leukemia: report from the Swedish phase Ulla trial

Enblad, Gunilla; Karlsson, Hannah; Wikström, Kristina I.; Essand, Magnus et al.

Ingår i CANCER IMMUNOLOGY RESEARCH, 2016

• DOI för CD19-targeting third generation CAR T cells for relapsed and refractory lymphoma and leukemia: report from the Swedish phase Ulla trial

HAdV-2-suppressed growth of SV40 T antigen-transformed mouse mammary epithelial cell-induced tumours in SCID mice

Wu, Chengjun; Cao, Xiaofang; Yu, Di; Huijbers, Elisabeth J. M. et al.

Ingår i Virology, s. 44-50, 2016

• DOI för HAdV-2-suppressed growth of SV40 T antigen-transformed mouse mammary epithelial cell-induced tumours in SCID mice

Heparanase Promotes Glioma Progression and is Inversely Correlated with Patient Survival.

Kundu, Soumi; Xiong, Anqi; Spyrou, Argyris; Wicher, Grzegorz et al.

Ingår i Molecular Cancer Research, s. 1243-1253, 2016

• DOI för Heparanase Promotes Glioma Progression and is Inversely Correlated with Patient Survival.

Long-term episomal gene transfer for safe engineering of T cells for adoptive cell therapy of cancer

Jin, Chuan; Ramachandran, Mohanraj; Fotaki, Grammatiki; Nilsson, Berith et al.

Ingår i CANCER IMMUNOLOGY RESEARCH, 2016

• DOI för Long-term episomal gene transfer for safe engineering of T cells for adoptive cell therapy of cancer

miR-196a Is Specifically Regulated in FDG-PET Positive and Negative Small Intestinal Neuroendocrine Tumor Patients at Late Stage of Disease

Giandomenico, V; Li, Su-Chen; Lind, Thomas; Boccherini, M. et al.

Ingår i Neuroendocrinology, s. 115-115, 2016

Prospects to improve chimeric antigen receptor T-cell therapy for solid tumors

Jin, Chuan; Yu, Di; Essand, Magnus

Ingår i Immunotherapy, s. 1355-1361, 2016

• DOI för Prospects to improve chimeric antigen receptor T-cell therapy for solid tumors

Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer

Jin, Chuan; Fotaki, Grammatiki; Ramachandran, Mohanraj; Nilsson, Berith et al.

Ingår i EMBO Molecular Medicine, s. 702-711, 2016

• DOI för Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer
• Ladda ner fulltext (pdf) av Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer

Chimeric Antigen Receptor-Engineered T Cells for the Treatment of Metastatic Prostate Cancer

Hillerdal, Victoria; Essand, Magnus

Ingår i BioDrugs, s. 75-89, 2015

• DOI för Chimeric Antigen Receptor-Engineered T Cells for the Treatment of Metastatic Prostate Cancer
• Ladda ner fulltext (pdf) av Chimeric Antigen Receptor-Engineered T Cells for the Treatment of Metastatic Prostate Cancer

Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Langenkamp, Elise; Zhang, Lei; Lugano, Roberta; Huang, Hua et al.

Ingår i Cancer Research, s. 4504-4516, 2015

• DOI för Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Immunological shielding by induced recruitment of regulatory T lymphocytes delays rejection of islets transplanted to muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Waldén, Tomas B; Carlsson, Per-Ola et al.

Ingår i Cell Transplantation, s. 263-276, 2015

• DOI för Immunological shielding by induced recruitment of regulatory T lymphocytes delays rejection of islets transplanted to muscle

Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Waldén, Tomas B; Carlsson, Per-Ola et al.

Ingår i Cell Transplantation, s. 263-276, 2015

• DOI för Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle

Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model

Fransson, Moa; Brännström, Johan; Duprez, Ida; Essand, Magnus et al.

Ingår i Regenerative Medicine Research, 2015

• DOI för Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model
• Ladda ner fulltext (pdf) av Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model

Other Novel Therapies: Biomarkers, microRNAs and microRNA Inhibitors, DNA Methylation, Epigenetics, Immunotherapy and Virotherapy

Giandomenico, Valeria; Thirlwell, Chrissie; Essand, Magnus

Ingår i Neuroendocrine Tumors, s. 248-262, S. Karger, 2015

• DOI för Other Novel Therapies: Biomarkers, microRNAs and microRNA Inhibitors, DNA Methylation, Epigenetics, Immunotherapy and Virotherapy

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Zhang, Lei; Kundu, Soumi; Feenstra, Tjerk; Li, Xiujuan et al.

Ingår i Science Signaling, 2015

• DOI för Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Third Generation CD19-CAR T Cells for Relapsed and Refractory Lymphoma and Leukemia Report from the Swedish Phase I/IIa Trial

Enblad, Gunilla; Karlsson, Hannah; Wikström, Kristina; Essand, Magnus et al.

Ingår i Blood, 2015

A Hexon and Fiber-modified Adenovirus Expressing CD40L Improves the Antigen Presentation Capacity of Dendritic Cells

Liljenfeldt, Lina; Yu, Di; Chen, Liye; Essand, Magnus et al.

Ingår i Journal of immunotherapy (1997), s. 155-162, 2014

• DOI för A Hexon and Fiber-modified Adenovirus Expressing CD40L Improves the Antigen Presentation Capacity of Dendritic Cells

Adenovirus Encoded Helicobacter pylori Neutrophil Activating Protein Promotes Maturation of DCs with Th-1 Polarization, Improved Antigen Presentation and Migration

Ramachandran, Mohanraj; Jin, Chuan; Yu, Di; Eriksson, Fredrik et al.

Ingår i Molecular Therapy, 2014

Allogeneic lymphocyte-licensed DCs expand T cells withimproved antitumor activity and resistance to oxidative stress andimmunosuppressive factors

Jin, Chuan; Yu, Di; Hillerdal, Victoria; Wallgren, AnnaCarin et al.

Ingår i Molecular Therapy Methods & Clinical Development, 2014

• DOI för Allogeneic lymphocyte-licensed DCs expand T cells withimproved antitumor activity and resistance to oxidative stress andimmunosuppressive factors

Allogeneic Lymphocyte-Licensed DCs Expand TCR/CAR-Engineered T Cells, Which Are Insensitive To Oxidative Stress and Immunosuppressive Factors

Jin, Chuan; Yu, Di; Karlsson-Parra, Alex; Essand, Magnus

Ingår i Molecular Therapy, 2014

Engineering Regulatory Cells With a T Cell Receptor for Controlled Activation

Hillerdal, Victoria; Berglund, David; Boura, Vanessa; Jin, Chuan et al.

Ingår i Molecular Therapy, 2014

Histidine-Rich Glycoprotein (HRG): A Novel Gene-Therapy Effector for the Treatment of Cancer

Roche, Francis P.; Ohlin, Elisabet K.; Essand, Magnus; Claesson-Welsh, Lena

Ingår i Molecular Therapy, 2014

Long-term episomal gene transfer for safe engineering of T-cells for adoptive cell therapy of cancer

Jin, Chuan; Ramachandran, Mohanraj; Fotaki, Grammatiki; Nilsson, Bo et al.

Ingår i Human Gene Therapy, 2014

Preclinical Safety Assessment of Ad[I/PPT-E1A], a Novel Oncolytic Adenovirus for Prostate Cancer

Schenk, Ellen; Essand, Magnus; Kraaij, Robert; Adamson, Rachel et al.

Ingår i Human Gene Therapy Clinical Development, s. 7-15, 2014

• DOI för Preclinical Safety Assessment of Ad[I/PPT-E1A], a Novel Oncolytic Adenovirus for Prostate Cancer

Strategical steering of the immune system: induction of leukocyte vascular chaperoning increases functional blood flow responses in ischemic muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Korsgren, Olle; Essand, Magnus et al.

Ingår i The FASEB Journal, 2014

Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice

Hillerdal, Victoria; Ramachandran, Mohanraj; Leja, Justyna; Essand, Magnus

Ingår i BMC Cancer, s. 30, 2014

• DOI för Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice
• Ladda ner fulltext (pdf) av Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice

Vector-Encoded Helicobacter pylori Neutrophil-Activating Protein Promotes Maturation of Dendritic Cells with Th1 Polarization and Improved Migration

Ramachandran, Mohanraj; Jin, Chuan; Yu, Di; Eriksson, Fredrik et al.

Ingår i Journal of Immunology, s. 2287-2296, 2014

• DOI för Vector-Encoded Helicobacter pylori Neutrophil-Activating Protein Promotes Maturation of Dendritic Cells with Th1 Polarization and Improved Migration

Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures

Yu, Di; Jin, Chuan; Ramachandran, Mohanraj; Xu, Jing et al.

Ingår i PLOS ONE, 2013

• DOI för Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures
• Ladda ner fulltext (pdf) av Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures

An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors

Ramachandran, Mohanraj; Yu, Di; Wanders, Alkwin; Essand, Magnus et al.

Ingår i Molecular Therapy, s. 2008-2018, 2013

• DOI för An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors
• Ladda ner fulltext (pdf) av An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors

Combining CAR T cells and the Bcl-2 family apoptosis inhibitor ABT-737 for treating B-cell malignancy

Karlsson, S. C. Hannah; Lindqvist, A. C.; Fransson, Moa; Paul-Wetterberg, Gabriella et al.

Ingår i Cancer Gene Therapy, s. 386-393, 2013

• DOI för Combining CAR T cells and the Bcl-2 family apoptosis inhibitor ABT-737 for treating B-cell malignancy

Genetically engineered T cells for the treatment of cancer

Essand, Magnus; Loskog, Angelica S I

Ingår i Journal of Internal Medicine, s. 166-181, 2013

• DOI för Genetically engineered T cells for the treatment of cancer

Histidine-Rich Glycoprotein (HRG): A Novel Gene-Therapy Effector for the Treatment of Cancer

Roche, Francis P.; Ohlin, Elisabet; Essand, Magnus; Claesson-Welsh, Lena

Ingår i Molecular Therapy, 2013

Islet Engraftment and Revascularization in Clinical and Experimental Transplantation

Molnár, Christian; Essand, Magnus; Wennberg, Lars; Berne, Christian et al.

Ingår i Cell Transplantation, s. 243-251, 2013

• DOI för Islet Engraftment and Revascularization in Clinical and Experimental Transplantation

Macrophage delivery of an oncolytic virus abolishes tumor regrowth and metastasis after chemotherapy or irradiation

Muthana, M.; Rodrigues, S.; Chen, Y. -Y; Welford, A. et al.

Ingår i Cancer Research, s. 490-495, 2013

• DOI för Macrophage delivery of an oncolytic virus abolishes tumor regrowth and metastasis after chemotherapy or irradiation

Strategic recruitment of proangiogenic leukocytes to the ischemic hindlimb increases functional tissue perfusion

Vågesjö, Evalina; Christoffersson, Gustaf; Korsgren, Olle; Essand, Magnus et al.

Ingår i European Journal of Clinical Investigation, s. 27-27, 2013

Tat‐PTD‐modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy

Jin, Chuan; Yu, Di; Čančer, Matko; Nilsson, Berith et al.

Ingår i Human Gene Therapy, s. 766-775, 2013

• DOI för Tat‐PTD‐modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy
• Ladda ner fulltext (pdf) av Tat‐PTD‐modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy

Virotherapy of Neuroendocrine Tumors

Essand, Magnus

Ingår i Neuroendocrinology, s. 26-34, 2013

• DOI för Virotherapy of Neuroendocrine Tumors